Chemical Formula: C7H8N2O2
Chemical Formula C7H8N2O2
Found 226 metabolite its formula value is C7H8N2O2
N1-Methyl-4-pyridone-3-carboxamide
N1-Methyl-4-pyridone-3-carboxamide is a normal human metabolite (one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation). Its concentration in serum is elevated in non-dialyzed chronic renal failure (CRF) patients when compared with controls. (PMID 12694300). N1-Methyl-4-pyridone-3-carboxamide has been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). N1-Methyl-4-pyridone-5-carboxamide (4PY ) is a normal human metabolite (one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation). 4PY concentration in serum is elevated in non-dialyzed chronic renal failure (CRF) patients when compared with controls. (PMID 12694300) [HMDB]
N1-Methyl-2-pyridone-5-carboxamide
N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin. (PMID 12694300). 2PY has been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin. (PMID 12694300) [HMDB] Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE0; CorrDec
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE10; CorrDec
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE30; CorrDec
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE0; MS2Dec
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE10; MS2Dec
N1-Methyl-4-pyridone-3-carboxamide; AIF; CE30; MS2Dec
1H-1,2-Diazepine-1-carboxylicacid,methylester(9CI)
2,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid
6,8-dihydro-5H-imidazo[2,1-c][1,4]oxazine-2-carbaldehyde
6,7-dihydro-5h-pyrrolo[1,2-a]imidazole-3-carboxylic acid
(6Z)-6-[amino-(hydroxyamino)methylidene]cyclohexa-2,4-dien-1-one
1H-Imidazole-5-carboxylicacid,1-(2-propenyl)-(9CI)
1H-Imidazole-2-carboxylicacid,1-ethenyl-,methylester(9CI)
1H-Imidazole-4-carboxylicacid,2-ethenyl-,methylester(9CI)
1H-Imidazole-5-carboxylicacid,1-ethenyl-,methylester(9CI)
1H-Imidazole-4-carboxylicacid,1-ethenyl-,methylester(9CI)
6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carbaldehyde
6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carbaldehyde
Cyclopropanecarboxylic acid, 2-(1H-imidazol-4-yl)- (9CI)
2-PYRIMIDINECARBOXYLIC ACID,4,6-DIMETHYL-(6CI,9CI)
1H-Imidazole-1-carboxylicacid,2-propenylester(9CI)
1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid
5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid
5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].
N-Methyl-4-pyridone-3-carboxamide
A member of the class of 4-pyridones that is 4-pyridone substituted with a carboxamide group at C-3 and a methyl group at N-1.
N-methyl-6-pyridone-3-carboxamide
A pyridone that is 2-pyridone substituted with a carboxamide group at C-5 and a methyl group at N-1.