Chemical Formula: C3H6O4

Chemical Formula C3H6O4

Found 14 metabolite its formula value is C3H6O4

Glycerate

(2R)-2,3-dihydroxypropanoic acid

C3H6O4 (106.0266076)


Glyceric acid is a colourless syrupy acid, obtained from oxidation of glycerol. It is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria, an inborn error of metabolism, and D-glycerate anemia. Deficiency of human glycerate kinase leads to D-glycerate acidemia/D-glyceric aciduria. Symptoms of the disease include progressive neurological impairment, hypotonia, seizures, failure to thrive, and metabolic acidosis. At sufficiently high levels, glyceric acid can act as an acidogen and a metabotoxin. An acidogen is an acidic compound that induces acidosis, which has multiple adverse effects on many organ systems. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Glyceric acid is an organic acid. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis. Acidosis typically occurs when arterial pH falls below 7.35. In infants with acidosis, the initial symptoms include poor feeding, vomiting, loss of appetite, weak muscle tone (hypotonia), and lack of energy (lethargy). These can progress to heart abnormalities, seizures, coma, and possibly death. These are also the characteristic symptoms of untreated glyceric aciduria. Many affected children with organic acidemias experience intellectual disability or delayed development. In adults, acidosis or acidemia is characterized by headaches, confusion, feeling tired, tremors, sleepiness, and seizures. Elevated values may also be due to microbial sources such as yeast (Aspergillus, Penicillium, probably Candida) or due to dietary sources containing glycerol (glycerine). Glyceric acid is isolated from various plants (e.g. brassicas, pulses, and Vicia faba). A colorless syrupy acid, obtained from oxidation of glycerol. It is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria and D-glycerate anemia. Deficiency of human glycerate kinase leads to D-glycerate acidemia/D-glyceric aciduria. Symptoms of the disease include progressive neurological impairment, hypotonia, seizures, failure to thrive and metabolic acidosis.; Glyceric acid is a natural three-carbon sugar acid. Salts and esters of glyceric acid are known as glycerates. Glyceric acid is found in many foods, some of which are peanut, common grape, garden tomato (variety), and french plantain. Glyceric acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=473-81-4 (retrieved 2024-06-29) (CAS RN: 473-81-4). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

Glycerate

(2S)-2,3-Dihydroxy-propanoic acid

C3H6O4 (106.0266076)


L-glyceric acid is a human urinary metabolite present in patients with L-Glyceric aciduria. The formation of L-glyceric acid from accumulated hydroxypyruvate is due to deficiency of human glyoxylate reductase/hydroxypyruvate reductase (GRHPR, EC 1.1.1.81), a D-2-hydroxy-acid dehydrogenase that plays a critical role in the removal of the metabolic by-product glyoxylate from within the liver. Deficiency of this enzyme is the underlying cause of primary hyperoxaluria type 2 (PH2) and leads to increased urinary oxalate levels, formation of kidney stones and renal failure. (PMID: 16756993) [HMDB] L-glyceric acid is a human urinary metabolite present in patients with L-Glyceric aciduria. The formation of L-glyceric acid from accumulated hydroxypyruvate is due to deficiency of human glyoxylate reductase/hydroxypyruvate reductase (GRHPR, EC 1.1.1.81), a D-2-hydroxy-acid dehydrogenase that plays a critical role in the removal of the metabolic by-product glyoxylate from within the liver. Deficiency of this enzyme is the underlying cause of primary hyperoxaluria type 2 (PH2) and leads to increased urinary oxalate levels, formation of kidney stones and renal failure. (PMID: 16756993).

   

Propaneperoxoic acid, 2-hydroxy-

Propaneperoxoic acid, 2-hydroxy-

C3H6O4 (106.0266076)


   

2-(Hydroxymethoxy)acetic acid

2-(Hydroxymethoxy)acetic acid

C3H6O4 (106.0266076)


   

Glycerate

GLYCERIC ACID

C3H6O4 (106.0266076)


   

D-Glyceric acid

D-Glyceric acid

C3H6O4 (106.0266076)


The D-enantiomer of glyceric acid.

   

GLYCERIC ACID

D-(+)-Glyceric acid hemicalcium salt

C3H6O4 (106.0266076)


A trionic acid that consists of propionic acid substituted at positions 2 and 3 by hydroxy groups.

   

D-2,3-Dihydroxypropanoic acid

D-2,3-Dihydroxypropanoic acid

C3H6O4 (106.0266076)


   

Glyceric acid; LC-tDDA; CE10

Glyceric acid; LC-tDDA; CE10

C3H6O4 (106.0266076)


   

Glyceric acid; LC-tDDA; CE20

Glyceric acid; LC-tDDA; CE20

C3H6O4 (106.0266076)


   

L-Glyceric acid

2S,3-dihydroxy-propanoic acid

C3H6O4 (106.0266076)


An optically active form of glyceric acid having L-configuration.

   

Propaneperoxoic acid, 2-hydroxy-

Propaneperoxoic acid, 2-hydroxy-

C3H6O4 (106.0266076)


   

(2S)-2,3-dihydroxypropanoic acid

(2S)-2,3-dihydroxypropanoic acid

C3H6O4 (106.0266076)


   

(2R)-2,3-Dihydroxypropanoic acid

(2R)-2,3-Dihydroxypropanoic acid

C3H6O4 (106.0266076)