Exact Mass: 488.22304280000003
Exact Mass Matches: 488.22304280000003
Found 357 metabolites which its exact mass value is equals to given mass value 488.22304280000003
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Vardenafil
Vardenafil (Levitra) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. The cGMP in turn triggers smooth muscle relaxation, allowing increased blood flow into the penis, resulting in erection. The tissue concentration of cGMP is regulated by both the rates of synthesis and degradation via phosphodiesterases (PDEs). The most abundant PDE in the human corpus cavernosum is the cGMPspecific phosphodiesterase type 5 (PDE5); therefore, the inhibition of PDE5 enhances erectile function by increasing the amount of cGMP. G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Kanzonol L
Kanzonol L is found in herbs and spices. Kanzonol L is a constituent of Glycyrrhiza uralensis (Chinese licorice). Constituent of Glycyrrhiza uralensis (Chinese licorice). Kanzonol L is found in herbs and spices.
Rubraflavone D
Rubraflavone D is found in fruits. Rubraflavone D is a constituent of Morus rubra (red mulberry)
Homosildenafil
1-Ethyl-5-(5-piperazin-1-ylsulfonyl-2-propoxyphenyl)-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
Flemiphilippinin
Flemiphilippinin A is a natural product found in Flemingia prostrata and Flemingia macrophylla with data available.
Fruticolide (sesquiterpene dimer)
Amorin
Sanggenone K
Euchrenone a12
Flemiphilippinin A
Artelastin
dorsilurin C
homosildenafil
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
2-acetyldihydropenstemide|2-O-acetyldihydropenstemide
C23H36O11 (488.22575059999997)
(4E)-1,5-bis(4-hydroxyphenyl)-1-[(2E)-3-(4-acetoxyphenyl)-2-propenoxy]-2-(methoxymethyl)-4-pentene
5-allyl-3-(4-allyl-2-methoxyphenoxymethyl)-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrobenzofuran|tulsinol C
7,6-(2,2-dimethylpyrano)-5-hydroxy-3,4-(3,3-dimethylallyloxy)flavone|afzelin C
4-methoxy-2-methyl-5-(1-methylethyl)phenyl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside|5-methoxycarvacrol 2-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
C23H36O11 (488.22575059999997)
2,3-Dihydro-6,8-dihydroxy-4,11,11,15,15-pentamethyl-5-(3-methyl-2-butenyl)-7H-13c,2-(epoxymethano)-11H-1,10-dioxa-1H-dibenzo[a,kl]anthracene-7-one
2-[2-(2-Methoxy-4-allylphenoxy)-4-allyl-6-methoxyphenoxy]-4-allyl-6-methoxyphenol
6-allyl-3-(4-allyl-2-methoxyphenoxy)-3,8-dimethoxyflavan-4-ol|tulsinol B
2-(2,4-Dihydroxyphenyl)-3,10-bis(3-methyl-2-butenyl)-8,8-dimethyl-5-hydroxy-4H,8H-benzo[1,2-b:5,4-b]dipyran-4-one
Vardenafil
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents CONFIDENCE standard compound; INTERNAL_ID 2359 CONFIDENCE standard compound; INTERNAL_ID 8528
Cys Asn Pro Arg
C18H32N8O6S (488.21654120000005)
Cys Asn Arg Pro
C18H32N8O6S (488.21654120000005)
Cys Pro Asn Arg
C18H32N8O6S (488.21654120000005)
Cys Pro Arg Asn
C18H32N8O6S (488.21654120000005)
Cys Arg Asn Pro
C18H32N8O6S (488.21654120000005)
Cys Arg Pro Asn
C18H32N8O6S (488.21654120000005)
Asp Ile Asn Gln
C19H32N6O9 (488.22306619999995)
Asp Ile Gln Asn
C19H32N6O9 (488.22306619999995)
Asp Leu Asn Gln
C19H32N6O9 (488.22306619999995)
Asp Leu Gln Asn
C19H32N6O9 (488.22306619999995)
Asp Asn Ile Gln
C19H32N6O9 (488.22306619999995)
Asp Asn Leu Gln
C19H32N6O9 (488.22306619999995)
Asp Asn Gln Ile
C19H32N6O9 (488.22306619999995)
Asp Asn Gln Leu
C19H32N6O9 (488.22306619999995)
Asp Gln Ile Asn
C19H32N6O9 (488.22306619999995)
Asp Gln Leu Asn
C19H32N6O9 (488.22306619999995)
Asp Gln Asn Ile
C19H32N6O9 (488.22306619999995)
Asp Gln Asn Leu
C19H32N6O9 (488.22306619999995)
Asp Gln Gln Val
C19H32N6O9 (488.22306619999995)
Asp Gln Val Gln
C19H32N6O9 (488.22306619999995)
Asp Val Gln Gln
C19H32N6O9 (488.22306619999995)
Glu Phe Pro Pro
C24H32N4O7 (488.22708819999997)
Glu Ile Met Pro
Glu Ile Asn Asn
C19H32N6O9 (488.22306619999995)
Glu Ile Pro Met
Glu Leu Met Pro
Glu Leu Asn Asn
C19H32N6O9 (488.22306619999995)
Glu Leu Pro Met
Glu Met Ile Pro
Glu Met Leu Pro
Glu Met Pro Ile
Glu Met Pro Leu
Glu Asn Ile Asn
C19H32N6O9 (488.22306619999995)
Glu Asn Leu Asn
C19H32N6O9 (488.22306619999995)
Glu Asn Asn Ile
C19H32N6O9 (488.22306619999995)
Glu Asn Asn Leu
C19H32N6O9 (488.22306619999995)
Glu Asn Gln Val
C19H32N6O9 (488.22306619999995)
Glu Asn Val Gln
C19H32N6O9 (488.22306619999995)
Glu Pro Phe Pro
C24H32N4O7 (488.22708819999997)
Glu Pro Ile Met
Glu Pro Leu Met
Glu Pro Met Ile
Glu Pro Met Leu
Glu Pro Pro Phe
C24H32N4O7 (488.22708819999997)
Glu Gln Asn Val
C19H32N6O9 (488.22306619999995)
Glu Gln Val Asn
C19H32N6O9 (488.22306619999995)
Glu Val Asn Gln
C19H32N6O9 (488.22306619999995)
Glu Val Gln Asn
C19H32N6O9 (488.22306619999995)
Phe Glu Pro Pro
C24H32N4O7 (488.22708819999997)
Phe Pro Glu Pro
C24H32N4O7 (488.22708819999997)
Phe Pro Pro Glu
C24H32N4O7 (488.22708819999997)
Ile Asp Asn Gln
C19H32N6O9 (488.22306619999995)
Ile Asp Gln Asn
C19H32N6O9 (488.22306619999995)
Ile Glu Met Pro
Ile Glu Asn Asn
C19H32N6O9 (488.22306619999995)
Ile Glu Pro Met
Ile Met Glu Pro
Ile Met Pro Glu
Ile Asn Asp Gln
C19H32N6O9 (488.22306619999995)
Ile Asn Glu Asn
C19H32N6O9 (488.22306619999995)
Ile Asn Asn Glu
C19H32N6O9 (488.22306619999995)
Ile Asn Gln Asp
C19H32N6O9 (488.22306619999995)
Ile Pro Glu Met
Ile Pro Met Glu
Ile Gln Asp Asn
C19H32N6O9 (488.22306619999995)
Ile Gln Asn Asp
C19H32N6O9 (488.22306619999995)
Leu Asp Asn Gln
C19H32N6O9 (488.22306619999995)
Leu Asp Gln Asn
C19H32N6O9 (488.22306619999995)
Leu Glu Met Pro
Leu Glu Asn Asn
C19H32N6O9 (488.22306619999995)
Leu Glu Pro Met
Leu Met Glu Pro
Leu Met Pro Glu
Leu Asn Asp Gln
C19H32N6O9 (488.22306619999995)
Leu Asn Glu Asn
C19H32N6O9 (488.22306619999995)
Leu Asn Asn Glu
C19H32N6O9 (488.22306619999995)
Leu Asn Gln Asp
C19H32N6O9 (488.22306619999995)
Leu Pro Glu Met
Leu Pro Met Glu
Leu Gln Asp Asn
C19H32N6O9 (488.22306619999995)
Leu Gln Asn Asp
C19H32N6O9 (488.22306619999995)
Met Glu Ile Pro
Met Glu Leu Pro
Met Glu Pro Ile
Met Glu Pro Leu
Met Ile Glu Pro
Met Ile Pro Glu
Met Leu Glu Pro
Met Leu Pro Glu
Met Pro Glu Ile
Met Pro Glu Leu
Met Pro Ile Glu
Met Pro Leu Glu
Asn Cys Pro Arg
C18H32N8O6S (488.21654120000005)
Asn Cys Arg Pro
C18H32N8O6S (488.21654120000005)
Asn Asp Ile Gln
C19H32N6O9 (488.22306619999995)
Asn Asp Leu Gln
C19H32N6O9 (488.22306619999995)
Asn Asp Gln Ile
C19H32N6O9 (488.22306619999995)
Asn Asp Gln Leu
C19H32N6O9 (488.22306619999995)
Asn Glu Ile Asn
C19H32N6O9 (488.22306619999995)
Asn Glu Leu Asn
C19H32N6O9 (488.22306619999995)
Asn Glu Asn Ile
C19H32N6O9 (488.22306619999995)
Asn Glu Asn Leu
C19H32N6O9 (488.22306619999995)
Asn Glu Gln Val
C19H32N6O9 (488.22306619999995)
Asn Glu Val Gln
C19H32N6O9 (488.22306619999995)
Asn Ile Asp Gln
C19H32N6O9 (488.22306619999995)
Asn Ile Glu Asn
C19H32N6O9 (488.22306619999995)
Asn Ile Asn Glu
C19H32N6O9 (488.22306619999995)
Asn Ile Gln Asp
C19H32N6O9 (488.22306619999995)
Asn Leu Asp Gln
C19H32N6O9 (488.22306619999995)
Asn Leu Glu Asn
C19H32N6O9 (488.22306619999995)
Asn Leu Asn Glu
C19H32N6O9 (488.22306619999995)
Asn Leu Gln Asp
C19H32N6O9 (488.22306619999995)
Asn Asn Glu Ile
C19H32N6O9 (488.22306619999995)
Asn Asn Glu Leu
C19H32N6O9 (488.22306619999995)
Asn Asn Ile Glu
C19H32N6O9 (488.22306619999995)
Asn Asn Leu Glu
C19H32N6O9 (488.22306619999995)
Asn Pro Cys Arg
C18H32N8O6S (488.21654120000005)
Asn Pro Arg Cys
C18H32N8O6S (488.21654120000005)
Asn Gln Asp Ile
C19H32N6O9 (488.22306619999995)
Asn Gln Asp Leu
C19H32N6O9 (488.22306619999995)
Asn Gln Glu Val
C19H32N6O9 (488.22306619999995)
Asn Gln Ile Asp
C19H32N6O9 (488.22306619999995)
Asn Gln Leu Asp
C19H32N6O9 (488.22306619999995)
Asn Gln Val Glu
C19H32N6O9 (488.22306619999995)
Asn Arg Cys Pro
C18H32N8O6S (488.21654120000005)
Asn Arg Pro Cys
C18H32N8O6S (488.21654120000005)
Asn Val Glu Gln
C19H32N6O9 (488.22306619999995)
Asn Val Gln Glu
C19H32N6O9 (488.22306619999995)
Pro Cys Asn Arg
C18H32N8O6S (488.21654120000005)
Pro Cys Arg Asn
C18H32N8O6S (488.21654120000005)
Pro Glu Phe Pro
C24H32N4O7 (488.22708819999997)
Pro Glu Ile Met
Pro Glu Leu Met
Pro Glu Met Ile
Pro Glu Met Leu
Pro Glu Pro Phe
C24H32N4O7 (488.22708819999997)
Pro Phe Glu Pro
C24H32N4O7 (488.22708819999997)
Pro Phe Pro Glu
C24H32N4O7 (488.22708819999997)
Pro Ile Glu Met
Pro Ile Met Glu
Pro Leu Glu Met
Pro Leu Met Glu
Pro Met Glu Ile
Pro Met Glu Leu
Pro Met Ile Glu
Pro Met Leu Glu
Pro Asn Cys Arg
C18H32N8O6S (488.21654120000005)
Pro Asn Arg Cys
C18H32N8O6S (488.21654120000005)
Pro Pro Glu Phe
C24H32N4O7 (488.22708819999997)
Pro Pro Phe Glu
C24H32N4O7 (488.22708819999997)
Pro Arg Cys Asn
C18H32N8O6S (488.21654120000005)
Pro Arg Asn Cys
C18H32N8O6S (488.21654120000005)
Gln Asp Ile Asn
C19H32N6O9 (488.22306619999995)
Gln Asp Leu Asn
C19H32N6O9 (488.22306619999995)
Gln Asp Asn Ile
C19H32N6O9 (488.22306619999995)
Gln Asp Asn Leu
C19H32N6O9 (488.22306619999995)
Gln Asp Gln Val
C19H32N6O9 (488.22306619999995)
Gln Asp Val Gln
C19H32N6O9 (488.22306619999995)
Gln Glu Asn Val
C19H32N6O9 (488.22306619999995)
Gln Glu Val Asn
C19H32N6O9 (488.22306619999995)
Gln Ile Asp Asn
C19H32N6O9 (488.22306619999995)
Gln Ile Asn Asp
C19H32N6O9 (488.22306619999995)
Gln Leu Asp Asn
C19H32N6O9 (488.22306619999995)
Gln Leu Asn Asp
C19H32N6O9 (488.22306619999995)
Gln Asn Asp Ile
C19H32N6O9 (488.22306619999995)
Gln Asn Asp Leu
C19H32N6O9 (488.22306619999995)
Gln Asn Glu Val
C19H32N6O9 (488.22306619999995)
Gln Asn Ile Asp
C19H32N6O9 (488.22306619999995)
Gln Asn Leu Asp
C19H32N6O9 (488.22306619999995)
Gln Asn Val Glu
C19H32N6O9 (488.22306619999995)
Gln Gln Asp Val
C19H32N6O9 (488.22306619999995)
Gln Gln Val Asp
C19H32N6O9 (488.22306619999995)
Gln Val Asp Gln
C19H32N6O9 (488.22306619999995)
Gln Val Glu Asn
C19H32N6O9 (488.22306619999995)
Gln Val Asn Glu
C19H32N6O9 (488.22306619999995)
Gln Val Gln Asp
C19H32N6O9 (488.22306619999995)
Arg Cys Asn Pro
C18H32N8O6S (488.21654120000005)
Arg Cys Pro Asn
C18H32N8O6S (488.21654120000005)
Arg Asn Cys Pro
C18H32N8O6S (488.21654120000005)
Arg Asn Pro Cys
C18H32N8O6S (488.21654120000005)
Arg Pro Cys Asn
C18H32N8O6S (488.21654120000005)
Arg Pro Asn Cys
C18H32N8O6S (488.21654120000005)
Val Asp Gln Gln
C19H32N6O9 (488.22306619999995)
Val Glu Asn Gln
C19H32N6O9 (488.22306619999995)
Val Glu Gln Asn
C19H32N6O9 (488.22306619999995)
Val Asn Glu Gln
C19H32N6O9 (488.22306619999995)
Val Asn Gln Glu
C19H32N6O9 (488.22306619999995)
Val Gln Asp Gln
C19H32N6O9 (488.22306619999995)
Val Gln Glu Asn
C19H32N6O9 (488.22306619999995)
Val Gln Asn Glu
C19H32N6O9 (488.22306619999995)
Val Gln Gln Asp
C19H32N6O9 (488.22306619999995)
Kanzonol L
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-(2-methylpropyl)-4H-pyrazolo[4,3-d]pyrimidin-7-one
diphenoxylate hydrochloride
C30H33ClN2O2 (488.22304280000003)
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics C78276 - Agent Affecting Digestive System or Metabolism > C266 - Antidiarrheal Agent D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D005765 - Gastrointestinal Agents > D000930 - Antidiarrheals
ALLYL-2,3-DI-O-BENZYL-4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE
N4,N4-di([1,1-biphenyl]-4-yl)-[1,1-biphenyl]-4,4-diamine
4-o-acetyl-2,5-anhydro-1,3-o-isopropylidene-6-o-trityl-d-glucitol
2-[(1S,3S,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
3-({2-[(4-{[6-(Cyclohexylmethoxy)-9H-purin-2-YL]amino}phenyl)sulfonyl]ethyl}amino)propan-1-OL
N-(4-(4-(4-Morpholinyl)-6-(3-oxa-8-azabicyclo(3.2.1)oct-8-yl)-1,3,5-triazin-2-yl)phenyl)-N-4-pyridinylurea
C25H28N8O3 (488.22842579999997)
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
sodium(E)-((1R,4aS,4bS,8aS,10aS)-4b,8,8,10a-tetramethyl-1-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydrophenanthren-2(1H,3H,4bH)-ylidene)methyl sulfate
C25H37NaO6S (488.22084220000005)
A natural product found in Coscinoderma species.
4-[[[1-[[2-(3-Chlorophenyl)-5-methyl-4-oxazolyl]methyl]-3-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester
C25H33ClN4O4 (488.21902080000007)
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride
C30H33ClN2O2 (488.22304280000003)
2-[(1R,3R,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3R,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1R,3S,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
(2R,3R,3aS,9bS)-N-cyclobutyl-7-(4-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-2-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(1R,9S,10S,11S)-N-(cyclopropylmethyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(1S,9R,10R,11R)-10-(hydroxymethyl)-6-oxo-12-N-phenyl-11-N-propyl-5-pyrimidin-5-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11,12-dicarboxamide
(2S)-2-[(4R,5S)-8-[2-(2-fluorophenyl)ethynyl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-2-yl]-1-propanol
C26H33FN2O4S (488.21449500000006)
1-(4-chlorophenyl)-3-[(4S,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(2-chlorophenyl)-3-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5S,6S,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5R,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
N-[2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
(1R,9S,10S,11S)-12-(cyclopropylmethyl)-N-[(3-fluorophenyl)methyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(1R,9S,10S,11S)-10-(hydroxymethyl)-6-oxo-12-N-phenyl-11-N-propyl-5-pyrimidin-5-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11,12-dicarboxamide
1-(4-chlorophenyl)-3-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(4R,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(3-chlorophenyl)-3-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5R,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5S,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
1-(4-chlorophenyl)-3-[(5S,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
C25H33ClN4O4 (488.21902080000007)
N-[2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
2-[(1R,3R,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3S,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3R,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
(1S,9R,10R,11R)-12-(cyclopropylmethyl)-N-[(3-fluorophenyl)methyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(2S,3S,3aR,9bR)-N-cyclobutyl-7-(4-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(2-pyridinylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(1S,9R,10R,11R)-N-(cyclopropylmethyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
BF 4
An organic heterotetracyclic compound that is 2,3,10,12-tetrahydro-4H,11H-pyrano[2,3-a]xanthene-4,11-dione substituted by methyl groups at positions 6, 8, 10, and 10, and by hydroxy, isopropyl, methoxy, phenyl, and groups at positions 5, 12, 9, and 2, respectively (the S,S-enantiomer). It is isolated from the leaves of Baeckea frutescens and exhibits cytotoxicity against leukemia cells.
BF 5
An organic heterotetracyclic compound that is 2,3,10,12-tetrahydro-4H,11H-pyrano[2,3-a]xanthene-4,11-dione substituted by methyl groups at positions 6, 8, 10, and 10, and by hydroxy, isopropyl, methoxy, phenyl, and groups at positions 5, 12, 9, and 2, respectively (the S,R-enantiomer). It is isolated from the leaves of Baeckea frutescens and exhibits cytotoxicity against leukemia cells.
3-deamino-3-hydroxykanamycin X(2+)
An organic cation obtained by protonation of the primary amino groups of 3-deamino-3-hydroxykanamycin X.
JNJ-47965567
JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].
7-(2,4-dihydroxyphenyl)-4-hydroxy-6,9-bis(3-methylbut-2-en-1-yl)-2-(prop-1-en-2-yl)-2h,3h-furo[3,2-g]chromen-5-one
2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3,10-bis(3-methylbut-2-en-1-yl)pyrano[3,2-g]chromen-4-one
2-methoxy-4-{7-methoxy-3-[2-methoxy-4-(prop-2-en-1-yl)phenoxymethyl]-5-(prop-2-en-1-yl)-2,3-dihydro-1-benzofuran-2-yl}phenol
3-[2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)phenyl]-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)pyrano[2,3-h]chromen-4-one
(2s,3r,4s,5s,6r)-2-(5-isopropyl-4-methoxy-2-methylphenoxy)-6-({[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxane-3,4,5-triol
C23H36O11 (488.22575059999997)
(2r,12s)-5-hydroxy-12-isopropyl-9-methoxy-6,8,10,10-tetramethyl-2-phenyl-3,12-dihydro-2h-1,7-dioxatetraphene-4,11-dione
(2s)-5-hydroxy-2-(8-hydroxy-2,2-dimethylchromen-6-yl)-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-2h,3h-pyrano[2,3-f]chromen-4-one
(1s,19r)-10,14-dihydroxy-6,6,16,20,20-pentamethyl-15-(3-methylbut-2-en-1-yl)-7,21,23-trioxahexacyclo[11.8.1.1¹,¹⁹.0²,¹¹.0³,⁸.0¹⁷,²²]tricosa-2,4,8,10,13,15,17(22)-heptaen-12-one
(2r)-5-hydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-8,8-dimethyl-10-(3-methylbut-2-en-1-yl)-2h,3h-pyrano[3,2-g]chromen-4-one
(1r,9r,16r,18s,21s)-18-hydroxy-4,5-dimethoxy-2,18-bis(methoxycarbonyl)-2,12-diazahexacyclo[14.2.2.1⁹,¹².0¹,⁹.0³,⁸.0¹⁶,²¹]henicosa-3(8),4,6-trien-12-ium-12-olate
C25H32N2O8 (488.21585519999996)
n-(4-aminobutyl)-2,6-bis({[(2,3-dihydroxyphenyl)(hydroxy)methylidene]amino})hexanimidic acid
C24H32N4O7 (488.22708819999997)
(2s)-5-hydroxy-2-(8-hydroxy-2,2-dimethylchromen-6-yl)-8,8-dimethyl-10-(3-methylbut-2-en-1-yl)-2h,3h-pyrano[3,2-g]chromen-4-one
4-({[3-(acetyloxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-7-(hydroxymethyl)-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl 3-methylbutanoate
C23H36O11 (488.22575059999997)
(1r,18s,21s)-18-hydroxy-4,5-dimethoxy-2,18-bis(methoxycarbonyl)-2,12-diazahexacyclo[14.2.2.1⁹,¹².0¹,⁹.0³,⁸.0¹⁶,²¹]henicosa-3(8),4,6-trien-12-ium-12-olate
C25H32N2O8 (488.21585519999996)
20-hydroxy-18-(1h-indol-3-ylmethyl)-8,15,16-trimethyl-4,14-dioxa-19-azapentacyclo[10.8.0.0¹,¹⁷.0³,⁵.0¹³,¹⁵]icosa-10,19-diene-2,6-dione
(1s,3r,5r,8s,10e,12r,13s,15r,16s,17r)-20-hydroxy-18-(1h-indol-3-ylmethyl)-8,15,16-trimethyl-4,14-dioxa-19-azapentacyclo[10.8.0.0¹,¹⁷.0³,⁵.0¹³,¹⁵]icosa-10,19-diene-2,6-dione
10,14-dihydroxy-6,6,16,20,20-pentamethyl-15-(3-methylbut-2-en-1-yl)-7,21,23-trioxahexacyclo[11.8.1.1¹,¹⁹.0²,¹¹.0³,⁸.0¹⁷,²²]tricosa-2,4,8,10,13,15,17(22)-heptaen-12-one
2-methoxy-4-[(2s,3r)-7-methoxy-3-[2-methoxy-4-(prop-2-en-1-yl)phenoxymethyl]-5-(prop-2-en-1-yl)-2,3-dihydro-1-benzofuran-2-yl]phenol
2-methoxy-4-[(2r,3s)-8-methoxy-3-[2-methoxy-4-(prop-2-en-1-yl)phenoxy]-6-(prop-2-en-1-yl)-3,4-dihydro-2h-1-benzopyran-2-yl]phenol
(1'r,3s,3'r,3ar,7'r,8as,9'r,9ar,11'r)-5,8a,9',14'-tetramethyl-4'-methylidene-3a,4,9,9a-tetrahydro-6'-oxaspiro[naphtho[2,3-b]furan-3,12'-tetracyclo[9.2.2.0¹,⁹.0³,⁷]pentadecan]-14'-ene-2,5',6,10'-tetrone
(2r,12r)-5-hydroxy-12-isopropyl-6,8,8,10,10-pentamethyl-2-phenyl-3,12-dihydro-2h-1,7-dioxatetraphene-4,9,11-trione
5-hydroxy-12-isopropyl-6,8,8,10,10-pentamethyl-2-phenyl-3,12-dihydro-2h-1,7-dioxatetraphene-4,9,11-trione
2-(5-isopropyl-4-methoxy-2-methylphenoxy)-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxane-3,4,5-triol
C23H36O11 (488.22575059999997)
(2r)-5-hydroxy-2-(7-hydroxy-2,2-dimethylchromen-6-yl)-8,8-dimethyl-6-(3-methylbut-2-en-1-yl)-2h,3h-pyrano[2,3-f]chromen-4-one
(1s,4as,7s,7as)-4-({[(2r,3r,4s,5s,6r)-3-(acetyloxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-7-(hydroxymethyl)-1h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyran-1-yl 3-methylbutanoate
C23H36O11 (488.22575059999997)