Chemical Formula: C28H32N4O2S

Chemical Formula C28H32N4O2S

Found 1 metabolite its formula value is C28H32N4O2S

JNJ-47965567

JNJ-47965567

C28H32N4O2S (488.2245852)


JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].