Exact Mass: 488.22575059999997
Exact Mass Matches: 488.22575059999997
Found 500 metabolites which its exact mass value is equals to given mass value 488.22575059999997
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Vardenafil
Vardenafil (Levitra) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. The cGMP in turn triggers smooth muscle relaxation, allowing increased blood flow into the penis, resulting in erection. The tissue concentration of cGMP is regulated by both the rates of synthesis and degradation via phosphodiesterases (PDEs). The most abundant PDE in the human corpus cavernosum is the cGMPspecific phosphodiesterase type 5 (PDE5); therefore, the inhibition of PDE5 enhances erectile function by increasing the amount of cGMP. G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Kanzonol L
Kanzonol L is found in herbs and spices. Kanzonol L is a constituent of Glycyrrhiza uralensis (Chinese licorice). Constituent of Glycyrrhiza uralensis (Chinese licorice). Kanzonol L is found in herbs and spices.
Rubraflavone D
Rubraflavone D is found in fruits. Rubraflavone D is a constituent of Morus rubra (red mulberry)
Homosildenafil
1-Ethyl-5-(5-piperazin-1-ylsulfonyl-2-propoxyphenyl)-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
Flemiphilippinin
Flemiphilippinin A is a natural product found in Flemingia prostrata and Flemingia macrophylla with data available.
Fruticolide (sesquiterpene dimer)
Sanggenone K
Euchrenone a12
Flemiphilippinin A
Artelastin
dorsilurin C
homosildenafil
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
2-acetyldihydropenstemide|2-O-acetyldihydropenstemide
(4E)-1,5-bis(4-hydroxyphenyl)-1-[(2E)-3-(4-acetoxyphenyl)-2-propenoxy]-2-(methoxymethyl)-4-pentene
5-allyl-3-(4-allyl-2-methoxyphenoxymethyl)-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrobenzofuran|tulsinol C
7,6-(2,2-dimethylpyrano)-5-hydroxy-3,4-(3,3-dimethylallyloxy)flavone|afzelin C
4-methoxy-2-methyl-5-(1-methylethyl)phenyl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside|5-methoxycarvacrol 2-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
2,3-Dihydro-6,8-dihydroxy-4,11,11,15,15-pentamethyl-5-(3-methyl-2-butenyl)-7H-13c,2-(epoxymethano)-11H-1,10-dioxa-1H-dibenzo[a,kl]anthracene-7-one
2-[2-(2-Methoxy-4-allylphenoxy)-4-allyl-6-methoxyphenoxy]-4-allyl-6-methoxyphenol
6-allyl-3-(4-allyl-2-methoxyphenoxy)-3,8-dimethoxyflavan-4-ol|tulsinol B
2-(2,4-Dihydroxyphenyl)-3,10-bis(3-methyl-2-butenyl)-8,8-dimethyl-5-hydroxy-4H,8H-benzo[1,2-b:5,4-b]dipyran-4-one
Ala Asn Glu Arg
Ala Glu Asn Arg
Vardenafil
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents CONFIDENCE standard compound; INTERNAL_ID 2359 CONFIDENCE standard compound; INTERNAL_ID 8528
Ala Asp Gln Arg
Ala Asp Arg Gln
Ala Glu Arg Asn
Ala His Val Tyr
Ala His Tyr Val
Ala Asn Arg Glu
Ala Asn Val Trp
Ala Asn Trp Val
Ala Gln Asp Arg
Ala Gln Arg Asp
Ala Arg Asp Gln
Ala Arg Glu Asn
Ala Arg Asn Glu
Ala Arg Gln Asp
Ala Val His Tyr
Ala Val Asn Trp
Ala Val Trp Asn
Ala Val Tyr His
Ala Trp Asn Val
Ala Trp Val Asn
Ala Tyr His Val
Ala Tyr Val His
Cys Asn Pro Arg
Cys Asn Arg Pro
Cys Pro Asn Arg
Cys Pro Arg Asn
Cys Arg Asn Pro
Cys Arg Pro Asn
Asp Ala Gln Arg
Asp Ala Arg Gln
Asp Ile Asn Gln
Asp Ile Gln Asn
Asp Leu Asn Gln
Asp Leu Gln Asn
Asp Asn Ile Gln
Asp Asn Leu Gln
Asp Asn Gln Ile
Asp Asn Gln Leu
Asp Gln Ala Arg
Asp Gln Ile Asn
Asp Gln Leu Asn
Asp Gln Asn Ile
Asp Gln Asn Leu
Asp Gln Gln Val
Asp Gln Arg Ala
Asp Gln Val Gln
Asp Arg Ala Gln
Asp Arg Gln Ala
Asp Val Gln Gln
Glu Ala Asn Arg
Glu Ala Arg Asn
Glu Phe Pro Pro
Glu Gly Gln Arg
Glu Gly Arg Gln
Glu Ile Met Pro
Glu Ile Asn Asn
Glu Ile Pro Met
Glu Leu Met Pro
Glu Leu Asn Asn
Glu Leu Pro Met
Glu Met Ile Pro
Glu Met Leu Pro
Glu Met Pro Ile
Glu Met Pro Leu
Glu Asn Ala Arg
Glu Asn Ile Asn
Glu Asn Leu Asn
Glu Asn Asn Ile
Glu Asn Asn Leu
Glu Asn Gln Val
Glu Asn Arg Ala
Glu Asn Val Gln
Glu Pro Phe Pro
Glu Pro Ile Met
Glu Pro Leu Met
Glu Pro Met Ile
Glu Pro Met Leu
Glu Pro Pro Phe
Glu Gln Gly Arg
Glu Gln Asn Val
Glu Gln Arg Gly
Glu Gln Val Asn
Glu Arg Ala Asn
Glu Arg Gly Gln
Glu Arg Asn Ala
Glu Arg Gln Gly
Glu Val Asn Gln
Glu Val Gln Asn
Phe Glu Pro Pro
Phe His Ser Val
Phe His Val Ser
Phe Pro Glu Pro
Phe Pro Pro Glu
Phe Ser His Val
Phe Ser Val His
Phe Val His Ser
Phe Val Ser His
Gly Glu Gln Arg
Gly Glu Arg Gln
Gly His Ile Tyr
Gly His Leu Tyr
Gly His Tyr Ile
Gly His Tyr Leu
Gly Ile His Tyr
Gly Ile Asn Trp
Gly Ile Trp Asn
Gly Ile Tyr His
Gly Leu His Tyr
Gly Leu Asn Trp
Gly Leu Trp Asn
Gly Leu Tyr His
Gly Asn Ile Trp
Gly Asn Leu Trp
Gly Asn Trp Ile
Gly Asn Trp Leu
Gly Gln Glu Arg
Gly Gln Arg Glu
Gly Gln Val Trp
Gly Gln Trp Val
Gly Arg Glu Gln
Gly Arg Gln Glu
Gly Val Gln Trp
Gly Val Trp Gln
Gly Trp Ile Asn
Gly Trp Leu Asn
Gly Trp Asn Ile
Gly Trp Asn Leu
Gly Trp Gln Val
Gly Trp Val Gln
Gly Tyr His Ile
Gly Tyr His Leu
Gly Tyr Ile His
Gly Tyr Leu His
His Ala Val Tyr
His Ala Tyr Val
His Phe Ser Val
His Phe Val Ser
His Gly Ile Tyr
His Gly Leu Tyr
His Gly Tyr Ile
His Gly Tyr Leu
His Ile Gly Tyr
His Ile Tyr Gly
His Leu Gly Tyr
His Leu Tyr Gly
His Ser Phe Val
His Ser Val Phe
His Val Ala Tyr
His Val Phe Ser
His Val Ser Phe
His Val Tyr Ala
His Tyr Ala Val
Ile Asp Asn Gln
Ile Asp Gln Asn
Ile Glu Met Pro
Ile Glu Asn Asn
Ile Glu Pro Met
Ile Met Glu Pro
Ile Met Pro Glu
Ile Asn Asp Gln
Ile Asn Glu Asn
Ile Asn Asn Glu
Ile Asn Gln Asp
Ile Pro Glu Met
Ile Pro Met Glu
Ile Gln Asp Asn
Ile Gln Asn Asp
Lys Asn Asn Asn
Leu Asp Asn Gln
Leu Asp Gln Asn
Leu Glu Met Pro
Leu Glu Asn Asn
Leu Glu Pro Met
Leu Met Glu Pro
Leu Met Pro Glu
Leu Asn Asp Gln
Leu Asn Glu Asn
Leu Asn Asn Glu
Leu Asn Gln Asp
Leu Pro Glu Met
Leu Pro Met Glu
Leu Gln Asp Asn
Leu Gln Asn Asp
Met Glu Ile Pro
Met Glu Leu Pro
Met Glu Pro Ile
Met Glu Pro Leu
Met Ile Glu Pro
Met Ile Pro Glu
Met Leu Glu Pro
Met Leu Pro Glu
Met Pro Glu Ile
Met Pro Glu Leu
Met Pro Ile Glu
Met Pro Leu Glu
Asn Ala Glu Arg
Asn Ala Arg Glu
Asn Cys Pro Arg
Asn Cys Arg Pro
Asn Asp Ile Gln
Asn Asp Leu Gln
Asn Asp Gln Ile
Asn Asp Gln Leu
Asn Glu Ala Arg
Asn Glu Ile Asn
Asn Glu Leu Asn
Asn Glu Asn Ile
Asn Glu Asn Leu
Asn Glu Gln Val
Asn Glu Arg Ala
Asn Glu Val Gln
Asn Ile Asp Gln
Asn Ile Glu Asn
Asn Ile Asn Glu
Asn Ile Gln Asp
Asn Lys Asn Asn
Asn Leu Asp Gln
Asn Leu Glu Asn
Asn Leu Asn Glu
Asn Leu Gln Asp
Asn Asn Glu Ile
Asn Asn Glu Leu
Asn Asn Ile Glu
Asn Asn Lys Asn
Asn Asn Leu Glu
Asn Asn Asn Lys
Asn Pro Cys Arg
Asn Pro Arg Cys
Asn Gln Asp Ile
Asn Gln Asp Leu
Asn Gln Glu Val
Asn Gln Ile Asp
Asn Gln Leu Asp
Asn Gln Val Glu
Asn Arg Ala Glu
Asn Arg Cys Pro
Asn Arg Glu Ala
Asn Arg Pro Cys
Asn Val Glu Gln
Asn Val Gln Glu
Pro Cys Asn Arg
Pro Cys Arg Asn
Pro Glu Phe Pro
Pro Glu Ile Met
Pro Glu Leu Met
Pro Glu Met Ile
Pro Glu Met Leu
Pro Glu Pro Phe
Pro Phe Glu Pro
Pro Phe Pro Glu
Pro Ile Glu Met
Pro Ile Met Glu
Pro Leu Glu Met
Pro Leu Met Glu
Pro Met Glu Ile
Pro Met Glu Leu
Pro Met Ile Glu
Pro Met Leu Glu
Pro Asn Cys Arg
Pro Asn Arg Cys
Pro Pro Glu Phe
Pro Pro Phe Glu
Pro Arg Cys Asn
Pro Arg Asn Cys
Gln Ala Asp Arg
Gln Ala Arg Asp
Gln Asp Ala Arg
Gln Asp Ile Asn
Gln Asp Leu Asn
Gln Asp Asn Ile
Gln Asp Asn Leu
Gln Asp Gln Val
Gln Asp Arg Ala
Gln Asp Val Gln
Gln Glu Gly Arg
Gln Glu Asn Val
Gln Glu Arg Gly
Gln Glu Val Asn
Gln Gly Glu Arg
Gln Gly Arg Glu
Gln Ile Asp Asn
Gln Ile Asn Asp
Gln Leu Asp Asn
Gln Leu Asn Asp
Gln Asn Asp Ile
Gln Asn Asp Leu
Gln Asn Glu Val
Gln Asn Ile Asp
Gln Asn Leu Asp
Gln Asn Val Glu
Gln Gln Asp Val
Gln Gln Val Asp
Gln Arg Ala Asp
Gln Arg Asp Ala
Gln Arg Glu Gly
Gln Arg Gly Glu
Gln Val Asp Gln
Gln Val Glu Asn
Gln Val Asn Glu
Gln Val Gln Asp
Arg Ala Asp Gln
Arg Ala Glu Asn
Arg Ala Asn Glu
Arg Ala Gln Asp
Arg Cys Asn Pro
Arg Cys Pro Asn
Arg Asp Ala Gln
Arg Asp Gln Ala
Arg Glu Ala Asn
Arg Glu Gly Gln
Arg Glu Asn Ala
Arg Glu Gln Gly
Arg Gly Glu Gln
Arg Gly Gln Glu
Arg Asn Ala Glu
Arg Asn Cys Pro
Arg Asn Glu Ala
Arg Asn Pro Cys
Arg Pro Cys Asn
Arg Pro Asn Cys
Arg Gln Ala Asp
Arg Gln Asp Ala
Arg Gln Glu Gly
Arg Gln Gly Glu
Val Asp Gln Gln
Val Glu Asn Gln
Val Glu Gln Asn
Val Asn Glu Gln
Val Asn Gln Glu
Val Gln Asp Gln
Val Gln Glu Asn
Val Gln Asn Glu
Val Gln Gln Asp
Kanzonol L
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-(2-methylpropyl)-4H-pyrazolo[4,3-d]pyrimidin-7-one
diphenoxylate hydrochloride
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics C78276 - Agent Affecting Digestive System or Metabolism > C266 - Antidiarrheal Agent D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D005765 - Gastrointestinal Agents > D000930 - Antidiarrheals
ALLYL-2,3-DI-O-BENZYL-4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE
N4,N4-di([1,1-biphenyl]-4-yl)-[1,1-biphenyl]-4,4-diamine
4-o-acetyl-2,5-anhydro-1,3-o-isopropylidene-6-o-trityl-d-glucitol
2-[(1S,3S,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
3-({2-[(4-{[6-(Cyclohexylmethoxy)-9H-purin-2-YL]amino}phenyl)sulfonyl]ethyl}amino)propan-1-OL
N-(4-(4-(4-Morpholinyl)-6-(3-oxa-8-azabicyclo(3.2.1)oct-8-yl)-1,3,5-triazin-2-yl)phenyl)-N-4-pyridinylurea
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
sodium(E)-((1R,4aS,4bS,8aS,10aS)-4b,8,8,10a-tetramethyl-1-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydrophenanthren-2(1H,3H,4bH)-ylidene)methyl sulfate
A natural product found in Coscinoderma species.
4-[[[1-[[2-(3-Chlorophenyl)-5-methyl-4-oxazolyl]methyl]-3-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride
2-[(1R,3R,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3R,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1R,3S,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
(2R,3R,3aS,9bS)-N-cyclobutyl-7-(4-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-2-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(1R,9S,10S,11S)-N-(cyclopropylmethyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(1S,9R,10R,11R)-10-(hydroxymethyl)-6-oxo-12-N-phenyl-11-N-propyl-5-pyrimidin-5-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11,12-dicarboxamide
(2S)-2-[(4R,5S)-8-[2-(2-fluorophenyl)ethynyl]-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-2-yl]-1-propanol
1-(4-chlorophenyl)-3-[(4S,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(2-chlorophenyl)-3-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5S,6S,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5R,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
N-[2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
(1R,9S,10S,11S)-12-(cyclopropylmethyl)-N-[(3-fluorophenyl)methyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(1R,9S,10S,11S)-10-(hydroxymethyl)-6-oxo-12-N-phenyl-11-N-propyl-5-pyrimidin-5-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11,12-dicarboxamide
1-(4-chlorophenyl)-3-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(4R,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(3-chlorophenyl)-3-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5R,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5S,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
1-(4-chlorophenyl)-3-[(5S,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea
N-[2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
N-[2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]ethyl]-2-(4-morpholinyl)acetamide
2-[(1R,3R,4aS,9aR)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3S,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
2-[(1S,3R,4aR,9aS)-6-(dimethylamino)-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(4-phenoxyphenyl)methyl]acetamide
(1S,9R,10R,11R)-12-(cyclopropylmethyl)-N-[(3-fluorophenyl)methyl]-10-(hydroxymethyl)-6-oxo-5-pyridin-3-yl-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(2S,3S,3aR,9bR)-N-cyclobutyl-7-(4-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(2-pyridinylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(1S,9R,10R,11R)-N-(cyclopropylmethyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
BF 4
An organic heterotetracyclic compound that is 2,3,10,12-tetrahydro-4H,11H-pyrano[2,3-a]xanthene-4,11-dione substituted by methyl groups at positions 6, 8, 10, and 10, and by hydroxy, isopropyl, methoxy, phenyl, and groups at positions 5, 12, 9, and 2, respectively (the S,S-enantiomer). It is isolated from the leaves of Baeckea frutescens and exhibits cytotoxicity against leukemia cells.
BF 5
An organic heterotetracyclic compound that is 2,3,10,12-tetrahydro-4H,11H-pyrano[2,3-a]xanthene-4,11-dione substituted by methyl groups at positions 6, 8, 10, and 10, and by hydroxy, isopropyl, methoxy, phenyl, and groups at positions 5, 12, 9, and 2, respectively (the S,R-enantiomer). It is isolated from the leaves of Baeckea frutescens and exhibits cytotoxicity against leukemia cells.
3-deamino-3-hydroxykanamycin X(2+)
An organic cation obtained by protonation of the primary amino groups of 3-deamino-3-hydroxykanamycin X.
JNJ-47965567
JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].