Exact Mass: 438.2101
Exact Mass Matches: 438.2101
Found 500 metabolites which its exact mass value is equals to given mass value 438.2101
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Kurarinone
(2S)-(-)-kurarinone is a trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2 and 4, a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a trihydroxyflavanone, a monomethoxyflavanone and a member of 4-hydroxyflavanones. It is functionally related to a (2S)-flavanone. 7,2,4-Trihydroxy-8-lavandulyl-5-methoxyflavanone is a natural product found in Albizia julibrissin, Cunila, and other organisms with data available. A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2 and 4, a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation[1]. Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation[1].
Quinapril
Quinapril is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to quinaprilat (quinapril diacid) following oral administration. Quinaprilat is a competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Quinapril may be used to treat essential hypertension and congestive heart failure. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone
1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is a member of xanthones. 3,6-Dimethylmangostin is a natural product found in Garcinia cowa, Cratoxylum arborescens, and Garcinia mangostana with data available. 1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is found in fruits. 1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is a constituent of Garcinia mangostana (mangosteen). Constituent of Garcinia mangostana (mangosteen). 1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is found in fruits. Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca[1]. Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca[1].
Kanzonol G
Kanzonol G is found in herbs and spices. Kanzonol G is a constituent of Glycyrrhiza uralensis (Chinese licorice). Constituent of Glycyrrhiza uralensis (Chinese licorice). Kanzonol G is found in herbs and spices.
Kurarinone
Isokurarinone
Isokurarinone is a natural product found in Sophora davidii and Sophora flavescens with data available.
25-O-Methylarugosin A
Exiguaflavanone B
A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 2 and 6, a lavandulyl group at position 8 and a methoxy group at position 7. Isolated from Sophora exigua and Artemisia indica, it exhibits antimalarial activity.
Hiravanone
isosophoranone
Sophoraisoflavanone B
Amoradicin
(2S)-5,7,4-Trihydroxy-2-methoxy-8-prenyl-5-(1,1-dimethylallyl)flavanone
Homoflemingin
5,7,3-trihydroxy-4-methoxy-8,2-di(3-methyl-2-butenyl)-(2S)-flavanone
A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7 and 3, a methoxy group at position 4 and prenyl groups at positions 8 and 2. Isolated from Dendrolobium lanceolatum, it exhibits cytotoxic activity.
1-[3-(7-hydroperoxy-3,7-dimethylocta-2,5-dienyl)-2-hydroxy-4-methoxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
3-lavandulyl-4-methoxyl-2,2,4,6-tetrahydroxylchalcone
1-[2,4-dihydroxy-6-methoxy-3-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)phenyl]-3-(2,4-dihydroxyphenyl)prop-2-en-1-one
1-[3-(6-hydroperoxy-3,7-dimethylocta-2,7-dienyl)-2-hydroxy-4-methoxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
4,7-dihydroxy-5-methoxy-6,3-diprenylisoflavanquinone|licoriquinone B
3,4-Dihydro-5-hydroxy-7-methoxy-2,3-dimethyl-6-(3-methyl-2-butenyl)-4-oxo-beta-phenyl-2H-1-benzopyran-8-propanoic acid
3,5,7-Trihydroxy-2-(3-prenyl-4-methoxyphenyl)-8-prenyl-2,3-dihydro-4H-1-benzopyran-4-one
(2R,3R)-6-methyl-3-geranyl-2,3-trans-5,7,4-trihydroxyflavonol
2S-3-(2-hydroxy-3-methylbut-3-enyl)licoflavone-4-methyl ether
3-(3,7-dimethyl-octa-2,6-dienyl)-2,5,2,4-tetrahydroxy-5-methoxy-chalcone|3-(3,7-Dimethyl-octa-2,6-dienyl)-2,5,2,4-tetrahydroxy-5-methoxy-chalkon|Homoflemingin|Homoflemingin, 2.4-Dihydroxy-3-geranyl-5-<3-(2.5-dihydroxy-phenyl)-trans-acryloyl>-anisol
3,5,7-Trihydroxy-4-methoxy-5,6-diprenylisoflavanone
(1S,4aS,8aR)-7-[(1,4,4a,6,6,8a-Hexahydro-2,5,5,8a-tetramethyl-6-oxo-1-naphthalenyl)methoxy]-6,8-dimethoxy-2H-1-benzopyran-2-one
leachianoneA
Leachianone A is a trihydroxyflavanone that is (2S)-flavanone substituted by a lavandulyl group at position 8, hydroxy groups at positions 5, 7 and 4 and a methoxy group at position 2. Isolated from the roots of Sophora flavescens and Sophora leachiana, it exhibits antineoplastic and antimalarial activity. It has a role as a metabolite, an antineoplastic agent and an antimalarial. It is a monomethoxyflavanone, a trihydroxyflavanone and a member of 4-hydroxyflavanones. It is functionally related to a (2S)-flavanone. leachianone A is a natural product found in Sophora stenophylla, Sophora alopecuroides, and other organisms with data available. A trihydroxyflavanone that is (2S)-flavanone substituted by a lavandulyl group at position 8, hydroxy groups at positions 5, 7 and 4 and a methoxy group at position 2. Isolated from the roots of Sophora flavescens and Sophora leachiana, it exhibits antineoplastic and antimalarial activity. Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent[1]. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways[2]. Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent[1]. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways[2].
5,7-dihydroxy-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
5,7-dihydroxy-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
Ferocaulicin
Origin: Plant, Coumarins, Coumarin terpenoids, Sesquiterpenoids, Ferula terpenoids
Ala Phe Thr Thr
Ala Ser Val Tyr
Ala Ser Tyr Val
Ala Thr Phe Thr
Ala Thr Thr Phe
Ala Val Ser Tyr
Ala Val Tyr Ser
Ala Tyr Ser Val
Ala Tyr Val Ser
Glu Pro Pro Pro
Phe Ala Thr Thr
Phe Ser Ser Val
Phe Ser Val Ser
Phe Thr Ala Thr
Phe Thr Thr Ala
Phe Val Ser Ser
Gly Ile Ser Tyr
Gly Ile Tyr Ser
Gly Leu Ser Tyr
Gly Leu Tyr Ser
Gly Ser Ile Tyr
Gly Ser Leu Tyr
Gly Ser Tyr Ile
Gly Ser Tyr Leu
Gly Thr Val Tyr
Gly Thr Tyr Val
Gly Val Thr Tyr
Gly Val Tyr Thr
Gly Tyr Ile Ser
Gly Tyr Leu Ser
Gly Tyr Ser Ile
Gly Tyr Ser Leu
Gly Tyr Thr Val
Gly Tyr Val Thr
His Pro Ser Val
His Pro Val Ser
His Ser Pro Val
His Ser Val Pro
His Val Pro Ser
His Val Ser Pro
Ile Gly Ser Tyr
Ile Gly Tyr Ser
Ile Ser Gly Tyr
Ile Ser Tyr Gly
Ile Tyr Gly Ser
Ile Tyr Ser Gly
Leu Gly Ser Tyr
Leu Gly Tyr Ser
Leu Ser Gly Tyr
Leu Ser Tyr Gly
Leu Tyr Gly Ser
Leu Tyr Ser Gly
Pro Glu Pro Pro
Pro His Ser Val
Pro His Val Ser
Pro Pro Glu Pro
Pro Pro Pro Glu
Pro Ser His Val
Pro Ser Val His
Pro Val His Ser
Pro Val Ser His
Ser Ala Val Tyr
Ser Ala Tyr Val
Ser Phe Ser Val
Ser Phe Val Ser
Ser Gly Ile Tyr
Ser Gly Leu Tyr
Ser Gly Tyr Ile
Ser Gly Tyr Leu
Ser His Pro Val
Ser His Val Pro
Ser Ile Gly Tyr
Ser Ile Tyr Gly
Ser Leu Gly Tyr
Ser Leu Tyr Gly
Ser Pro His Val
Ser Pro Val His
Ser Ser Phe Val
Ser Ser Val Phe
Ser Val Ala Tyr
Ser Val Phe Ser
Ser Val His Pro
Ser Val Pro His
Ser Val Ser Phe
Ser Val Tyr Ala
Ser Tyr Ala Val
Ser Tyr Gly Ile
Ser Tyr Gly Leu
Ser Tyr Ile Gly
Ser Tyr Leu Gly
Ser Tyr Val Ala
Thr Ala Phe Thr
Thr Ala Thr Phe
Thr Phe Ala Thr
Thr Phe Thr Ala
Thr Gly Val Tyr
Thr Gly Tyr Val
Thr Thr Ala Phe
Thr Thr Phe Ala
Thr Val Gly Tyr
Thr Val Tyr Gly
Thr Tyr Gly Val
Thr Tyr Val Gly
Val Ala Ser Tyr
Val Ala Tyr Ser
Val Phe Ser Ser
Val Gly Thr Tyr
Val Gly Tyr Thr
Val His Pro Ser
Val His Ser Pro
Val Pro His Ser
Val Pro Ser His
Val Ser Ala Tyr
Val Ser Phe Ser
Val Ser His Pro
Val Ser Pro His
Val Ser Ser Phe
Val Ser Tyr Ala
Val Thr Gly Tyr
Val Thr Tyr Gly
Val Tyr Ala Ser
Val Tyr Gly Thr
Val Tyr Ser Ala
Val Tyr Thr Gly
Tyr Ala Ser Val
Tyr Ala Val Ser
Tyr Gly Ile Ser
Tyr Gly Leu Ser
Tyr Gly Ser Ile
Tyr Gly Ser Leu
Tyr Gly Thr Val
Tyr Gly Val Thr
Tyr Ile Gly Ser
Tyr Ile Ser Gly
Tyr Leu Gly Ser
Tyr Leu Ser Gly
Tyr Ser Ala Val
Tyr Ser Gly Ile
Tyr Ser Gly Leu
Tyr Ser Ile Gly
Tyr Ser Leu Gly
Tyr Ser Val Ala
Tyr Thr Gly Val
Tyr Thr Val Gly
Tyr Val Ala Ser
Tyr Val Gly Thr
Tyr Val Ser Ala
Tyr Val Thr Gly
EPOXY (1,2α)-7-DEACETOXY-7-OXO-DEOXYDIHYDROGEDUNIN
Leachianone A
Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent[1]. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways[2]. Leachianone A, isolated from Radix Sophorae, has anti-malarial, anti-inflammatory, and cytotoxic potent[1]. Leachianone A induces apoptosis involved both extrinsic and intrinsic pathways[2].
Fuscaxanthone C
Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca[1]. Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca[1].
Kanzonol G
glas#1
An ascarosyloxycarboxylic acid beta-D-glucopyranosyl ester resulting from the formal esterification of the carboxy group of ascr#1 with the anomeric hydroxy group of beta-D-glucopyranose. It is a metabolite of the nematode Caenorhabditis elegans.
5S-HYDROXY-6R-(S-(2-OXO-3-THIOPROPIONYL))-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID
3,6-diethyl-1-N,4-N-bis(3-methoxyphenyl)-1,2,4,5-tetrazine-1,4-dicarboxamide
4-(4-((4-Chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid
1,3-diisocyanato-2-methylbenzene,hexanedioic acid,hexane-1,6-diol
5-(2-(4-(2-(DIMETHYLAMINO)ETHOXY)PHENYL)-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)-2,3-DIHYDRO-1H-INDEN-1-ONE
butane-1,3-diol,2,2-dimethylpropane-1,3-diol,furan-2,5-dione,hexanedioic acid
3-(1H-Indol-3-YL)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-YL)-1H-pyrrole-2,5-dione
3-(1h-Indol-3-Yl)-4-{1-[2-(1-Methylpyrrolidin-2-Yl)ethyl]-1h-Indol-3-Yl}-1h-Pyrrole-2,5-Dione
beta-D-glucopyranosyl (6R)-6-[(3,6-dideoxy-alpha-L-arabino-hexopyranosyl)oxy]heptanoate
2-p-Chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol
10-[2-(morpholin-4-yl)ethyl]-12-phenyl-10,12-dihydro-11H-benzo[5,6]chromeno[2,3-d]pyrimidin-11-imine
3-[2-(1-adamantyl)ethylsulfamoyl]-N-phenylbenzamide
9-(2-Morpholin-4-yl-ethyl)-7-phenyl-7,9-dihydro-12-oxa-9,11-diaza-benzo[a]anthracen-8-ylideneamine
7-[3-[4-(2-Ethoxyphenyl)-1-piperazinyl]-2-hydroxypropoxy]-4-methyl-1-benzopyran-2-one
(1R)-N-(2-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1-spiro[1,2,3,9-tetrahydropyrido[3,4-b]indole-4,4-piperidine]carboxamide
N-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[(2S,3S,6R)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[(2S,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)triazol-1-yl]ethyl]oxan-3-yl]pyrazine-2-carboxamide
N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[(2R,3R,6S)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-2-pyrazinecarboxamide
N-[2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
N-[2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(4-methylphenyl)sulfonylamino]-2-oxanyl]ethyl]cyclohexanecarboxamide
(1S)-N-(2-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1-spiro[1,2,3,9-tetrahydropyrido[3,4-b]indole-4,4-piperidine]carboxamide
(1R)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-1-spiro[1,2,3,9-tetrahydropyrido[3,4-b]indole-4,4-piperidine]carboxamide
1-(3-Methoxypropyl)-4-[2-methyl-4-(2-methylpropoxy)benzoyl]-5-pyridin-3-ylpyrrolidine-2,3-dione
Quinapril
C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
5,7-diethyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3,4-dihydro-1,6-naphthyridin-2-one
D057911 - Angiotensin Receptor Antagonists > D047228 - Angiotensin II Type 1 Receptor Blockers
KT182
KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1].