Exact Mass: 393.21112780000004

Tylophorine

(+/-)-Tylophorine

2,2-Dimethyl-3-(4-methoxyphenyl)-4-ethyl-6-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol

2,2-Dimethyl-3-(4-methoxyphenyl)-4-ethyl-8-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol

Cyenopyrafen

(1E)-2-CYANO-2-[4-(1,1-DIMETHYLETHYL)PHENYL]-1-(1,3,4-TRIMETHYL-1H-PYRAZOL-5-YL)ETHENYL 2,2-DIMETHYLPROPANOATE

Branaplam

C22H27N5O2 (393.2164642)

C78272 - Agent Affecting Nervous System

Acidissiminol

N-[2-(4-{[(2E)-4-hydroxy-3,7-dimethylocta-2,6-dien-1-yl]oxy}phenyl)ethyl]benzenecarboximidate

C22H23N3O4 (393.16884780000004)

Acidissiminol is found in beverages. Acidissiminol is an alkaloid from the fruit of Limonia acidissima (wood apple). Alkaloid from the fruit of Limonia acidissima (wood apple). Acidissiminol is found in beverages and fruits.

Erlotinib

[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine

Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EB - Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163952 - EGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents

6'-Apiosyllotaustralin

2-{[6-({[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-2-methylbutanenitrile

C16H27NO10 (393.16348819999996)

6-Apiosyllotaustralin is found in root vegetables. 6-Apiosyllotaustralin is a constituent of the roots of Manihot esculenta (cassava). Constituent of the roots of Manihot esculenta (cassava). 6-Apiosyllotaustralin is found in root vegetables.

Epoxyfumitremorgin C

8-methoxy-13-(2-methylprop-1-en-1-yl)-2-oxa-11,14,20-triazahexacyclo[12.7.0.0¹,³.0⁴,¹².0⁵,¹⁰.0¹⁶,²⁰]henicosa-4(12),5(10),6,8-tetraene-15,21-dione

C22H23N3O4 (393.16884780000004)

Epoxyfumitremorgin C is from Aspergillus fumigatus. From Aspergillus fumigatus

(-)-Tylophorine

4,5,10,11-tetramethoxy-16-azapentacyclo[12.7.0.0²,⁷.0⁸,¹³.0¹⁶,²⁰]henicosa-1(14),2,4,6,8,10,12-heptaene

Adaphostin

adamantan-1-yl 4-{[(2,5-dihydroxyphenyl)methyl]amino}benzoate

C19H27N3O4S (393.17221820000003)

Daprodustat

2-(1,3-Dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic acid

C19H27N3O6 (393.1899762)

B - Blood and blood forming organs > B03 - Antianemic preparations C78275 - Agent Affecting Blood or Body Fluid Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.

1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulfonyl)amino)ethyl)-4-piperidinyl)methyl ester

1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulphonyl)amino)ethyl)-4-piperidinyl)methyl ester

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists GR 113808 is a potent and highly selective 5-HT4?receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors[1].

Lumateperone

1-(4-fluorophenyl)-4-{4-methyl-1,4,12-triazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-5,7,9(16)-trien-12-yl}butan-1-one

C24H28FN3O (393.221629)

N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AD - Butyrophenone derivatives C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent

1-(2-Methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine

2-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-2,3-dihydro-1H-isoindole-1,3-dione

C23H27N3O3 (393.20523120000007)

Pirenperone

3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

C23H24FN3O2 (393.1852456)

2-{[(1r,2s)-2-Aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-Triazol-2-Yl)phenyl]amino}pyrimidine-5-Carboxamide

2-[(2-Aminocyclohexyl)amino]-6-{[3-(2H-1,2,3-triazol-2-yl)phenyl]imino}-1,6-dihydropyrimidine-5-carboximidate

C19H23N9O (393.2025468)

10-(2-(Diethylamino)ethyl)-9(10H)-acridinone (4,5-dihydro-2-thiazolyl)hydrazone

(2-{9-[2-(4,5-dihydro-1,3-thiazol-2-yl)hydrazin-1-ylidene]-9,10-dihydroacridin-10-yl}ethyl)diethylamine

C22H27N5S (393.19870620000006)

Estradiol 17-dihydrotrigonelline

5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-14-yl 1-methyl-1,4-dihydropyridine-3-carboxylate

Buxifoliadine B

C20H27NO7 (393.17874320000004)

Acetylgynuramine

Gynuramine 19-O-acetate

An indole alkaloid isolated from a marine-derived fungal strain Aspergillus sydowii PFW1-13 and has been shown to exhibit cytotoxic activity.

Oprea1_721939

Maybridge3_002245

ADAMANTYL-THPINACA

ZINC575631098