Exact Mass: 393.1419

Exact Mass Matches: 393.1419

Found 500 metabolites which its exact mass value is equals to given mass value 393.1419, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

amsacrine

C21H19N3O3S (393.1147)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D000970 - Antineoplastic Agents

Dihydromacarpine

13,14-Dihydro-5,7-dimethoxy-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3- dioxolo[4,5-i]phenanthridine

C22H19NO6 (393.1212)

A benzophenanthridine alkaloid that is dihydrosanguinarine bearing two methoxy substituents.

Latifoline

(+)-Latifoline

C20H27NO7 (393.1787)

Tifluadom

N-{[5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl}thiophene-3-carboximidate

C22H20FN3OS (393.1311)

C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D045283 - Natriuretic Agents > D004232 - Diuretics Same as: D02694

Fruquintinib

C21H19N3O5 (393.1325)

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C93259 - VEGFR Tyrosine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163953 - VEGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor

(S)-N1-(2-(tert-butyl)-4-methyl-[4,5-bithiazol]-2-yl)pyrrolidine-1,2-dicarboxamide

C17H23N5O2S2 (393.1293)

gamma-L-Glutamyl-S-(2-carboxy-1-propyl)cysteinylglycine

2-Amino-4-({2-[(2-carboxy-2-methylethyl)sulphanyl]-1-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl}-C-hydroxycarbonimidoyl)butanoic acid

C14H23N3O8S (393.1206)

gamma-L-Glutamyl-S-(2-carboxy-1-propyl)cysteinylglycine is found in onion-family vegetables. gamma-L-Glutamyl-S-(2-carboxy-1-propyl)cysteinylglycine is a constituent of onion (Allium cepa) and garlic (Allium sativum) Constituent of onion (Allium cepa) and garlic (Allium sativum). gamma-L-Glutamyl-S-(2-carboxy-1-propyl)cysteinylglycine is found in garden onion, garlic, and onion-family vegetables.

Amsacrine

N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide

C21H19N3O3S (393.1147)

Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. [PubChem] C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D000970 - Antineoplastic Agents

(gamma-Glutamyl-gamma-glutamyl)-S-methylcysteine

2-Amino-4-[(1-carboxy-3-{[1-carboxy-2-(methylsulphanyl)ethyl]-C-hydroxycarbonimidoyl}propyl)-C-hydroxycarbonimidoyl]butanoic acid

C14H23N3O8S (393.1206)

(gamma-Glutamyl-gamma-glutamyl)-S-methylcysteine is found in pulses. (gamma-Glutamyl-gamma-glutamyl)-S-methylcysteine is a constituent of the seeds of Vigna radiata (mung bean). Constituent of the seeds of Vigna radiata (mung bean). (gamma-Glutamyl-gamma-glutamyl)-S-methylcysteine is found in pulses.

Erlotinib

[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine

C22H23N3O4 (393.1688)

Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EB - Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163952 - EGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents

6'-Apiosyllotaustralin

2-{[6-({[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-2-methylbutanenitrile

C16H27NO10 (393.1635)

6-Apiosyllotaustralin is found in root vegetables. 6-Apiosyllotaustralin is a constituent of the roots of Manihot esculenta (cassava). Constituent of the roots of Manihot esculenta (cassava). 6-Apiosyllotaustralin is found in root vegetables.

Epoxyfumitremorgin C

8-methoxy-13-(2-methylprop-1-en-1-yl)-2-oxa-11,14,20-triazahexacyclo[12.7.0.0¹,³.0⁴,¹².0⁵,¹⁰.0¹⁶,²⁰]henicosa-4(12),5(10),6,8-tetraene-15,21-dione

C22H23N3O4 (393.1688)

Epoxyfumitremorgin C is from Aspergillus fumigatus. From Aspergillus fumigatus

Besifloxacin

7-(3-aminoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C19H21ClFN3O3 (393.1255)

N-Hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide hydrochloride

N-Hydroxy-2(R)-[[(4-methoxyphenyl)sulphonyl](3-picolyl)amino]-3-methylbutanamide hydrochloride

C18H23N3O5S (393.1358)

Daprodustat

2-(1,3-Dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic acid

C19H27N3O6 (393.19)

B - Blood and blood forming organs > B03 - Antianemic preparations C78275 - Agent Affecting Blood or Body Fluid Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.

gamma-Glutamylfelinylglycine

2-Amino-5-[[1-(carboxymethylamino)-3-(4-hydroxy-2-methylbutan-2-yl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

C15H27N3O7S (393.157)

1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulfonyl)amino)ethyl)-4-piperidinyl)methyl ester

1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulphonyl)amino)ethyl)-4-piperidinyl)methyl ester

C19H27N3O4S (393.1722)

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists GR 113808 is a potent and highly selective 5-HT4?receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors[1].

Pentetic acid

[[(Carboxymethyl)imino]bis(1,2-ethanediylnitrilo)tetraacetic acid]

C14H23N3O10 (393.1383)

Pirenperone

3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

C23H24FN3O2 (393.1852)

Q-100035

19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

C20H15N3O6 (393.0961)

1-[5-(2-Cyclopropyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]cyclopent-3-ene carboxylic acid

1-[5-({2-cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl}methyl)thiophen-2-yl]cyclopent-3-ene-1-carboxylic acid

C22H23N3O2S (393.1511)

4-(2-Aminoethylamino)-3-[bis(carboxymethyl)amino]-3-(carboxymethyl)hexanedioic acid

4-[(2-aminoethyl)amino]-3-[bis(carboxymethyl)amino]-3-(carboxymethyl)hexanedioic acid

C14H23N3O10 (393.1383)

Rubitecan

(19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

C20H15N3O6 (393.0961)

Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone. Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks. (NCI04) C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059004 - Topoisomerase I Inhibitors C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C1748 - Topoisomerase Inhibitor D004791 - Enzyme Inhibitors Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells[1][2][3].

Waltherione B

C23H23NO5 (393.1576)

Acetylgynuramine

Gynuramine 19-O-acetate

C20H27NO7 (393.1787)

An indole alkaloid isolated from a marine-derived fungal strain Aspergillus sydowii PFW1-13 and has been shown to exhibit cytotoxic activity.

UNII-BAB5UV995D

C24H21ClFNO (393.1296)

SCHEMBL16724509

C23H15N5S (393.1048)

H-GLU-VAL-PHE-OH

Glutamyl-valyl-phenylalanine

C19H27N3O6 (393.19)

Pirenperone

C23H24FN3O2 (393.1852)

D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].