Exact Mass: 392.137215

Exact Mass Matches: 392.137215

Found 500 metabolites which its exact mass value is equals to given mass value 392.137215, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Shanziside

(1S,4aS,5R,7S,7aS)-5,7-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylic acid

C16H24O11 (392.13185539999995)

Shanzhiside is a terpene glycoside. Shanzhiside is a natural product found in Barleria lupulina, Gardenia jasminoides, and other organisms with data available. Shanziside is a iridoid glucoside isolated from Phlomis tuberosa L[1]. Shanziside is a iridoid glucoside isolated from Phlomis tuberosa L[1].

Sparfloxacin

5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C19H22F2N4O3 (392.1659886)

Sparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D000995 - Antitubercular Agents D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic D004791 - Enzyme Inhibitors

Vernodalol

C20H24O8 (392.1471104)

Macarpine

C22H18NO6+ (392.1134068)

A benzophenanthridine alkaloid that is sanguinarine bearing two methoxy substituents.

Eupatoroxin

C20H24O8 (392.1471104)

7-Ethyl-10-hydroxycamptothecin

(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

C22H20N2O5 (392.137215)

SN-38 is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an apoptosis inducer, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, a drug metabolite and an antineoplastic agent. It is a pyranoindolizinoquinoline, a delta-lactone, a tertiary alcohol and a member of phenols. 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others. 7-Ethyl-10-hydroxycamptothecin is a natural product found in Apis cerana with data available. A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS. 7-Ethyl-10-hydroxycamptothecin (SN38) is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor); it is 1000 times more active than irinotecan itself. In vitro cytotoxicity assays show that the potency of SN-38 relative to irinotecan varies from 2- to 2000-fold. SN38 is metabolized via glucoronidation by UGT1A1. (Wikipedia) 7-Ethyl-10-hydroxycamptothecin (SN38), the active metabolite of irinotecan, exerts a 100-fold to 1000-fold higher effect than irinotecan itself against several tumor cell lines. (PMID: 23233044) Among five chemotherapeutic agents commonly used for breast cancer treatment, only an irinotecan metabolite SN38 showed additive antitumor activity with olaparib. (PMID: 22454224) Metabolism of irinotecan to SN38 is inefficient and subject to considerable patient-to-patient variability. One approach to more controlled administration of the anticancer agent is direct administration of the active SN38. (PMID: 23299391) A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively[1][2][3][4]. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively[1][2][3][4].

1,1'-Bis(2-hydroxy-3-methylcarbazole)

1-(2-hydroxy-3-methyl-9H-carbazol-1-yl)-3-methyl-9H-carbazol-2-ol

C26H20N2O2 (392.15247)

1,1-Bis(2-hydroxy-3-methylcarbazole) is found in herbs and spices. 1,1-Bis(2-hydroxy-3-methylcarbazole) is an alkaloid from roots of Murraya koenigii (curryleaf tree). Alkaloid from roots of Murraya koenigii (curryleaf tree). 1,1-Bis(2-hydroxy-3-methylcarbazole) is found in herbs and spices.

Caryoptosidic acid

6,7-dihydroxy-7-methyl-1-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylic acid

C16H24O11 (392.13185539999995)

Caryoptosidic acid is found in herbs and spices. Caryoptosidic acid is a constituent of Lippia graveolens (Mexican oregano) Constituent of Lippia graveolens (Mexican oregano). Caryoptosidic acid is found in herbs and spices.

Garcimangosone D

[2,4-Dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-phenylmethanone

C19H20O9 (392.110727)

Garcimangosone D is found in fruits. Garcimangosone D is a constituent of the dried fruit hulls of Garcinia mangostana (mangosteen). Constituent of the dried fruit hulls of Garcinia mangostana (mangosteen). Garcimangosone D is found in fruits.

Calabaxanthone

5-hydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-2,6-dihydro-1,11-dioxatetracen-6-one

C24H24O5 (392.1623654)

Calabaxanthone is found in fruits. Calabaxanthone is a constituent of Garcinia mangostana (mangosteen)

Marmesin rhamnoside

2-{2-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]propan-2-yl}-2H,3H,7H-furo[3,2-g]chromen-7-one

C20H24O8 (392.1471104)

Marmesin rhamnoside is found in fruits. Marmesin rhamnoside is isolated from the stem bark of Aegle marmelos (bael fruit). Isolated from the stem bark of Aegle marmelos (bael fruit). Marmesin rhamnoside is found in fruits.

cyclic N-Acetylserotonin glucuronide

6-({1-acetyl-1H,2H,3H,8H-pyrrolo[2,3-b]indol-5-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid

C18H20N2O8 (392.12196)

cyclic N-Acetylserotonin glucuronide is a metabolite of melatonin. Melatonin Listen/ˌmɛləˈtoʊnɪn/, also known chemically as N-acetyl-5-methoxytryptamine, is a naturally occurring compound found in animals, plants, and microbes. In animals, circulating levels of the hormone melatonin vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions. (Wikipedia)

1,3-Dipropyl-8-p-sulfophenylxanthine

4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzene-1-sulfonic acid

C17H20N4O5S (392.11543500000005)

D018377 - Neurotransmitter Agents > D058905 - Purinergic Agents > D058914 - Purinergic Antagonists

Cloprednol

8-chloro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6,8-trien-5-one

C21H25ClO5 (392.139043)

Fenflumizole

2-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazole

C23H18F2N2O2 (392.1336271999999)

4-Amino-5-[[2-[[1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]acetyl]amino]-5-oxopentanoic acid

C14H25ClN6O5 (392.157487)

Mesuol

5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-6-(2-methylpropanoyl)-4-phenyl-2H-chromen-2-one

C24H24O5 (392.1623654)

Mardepodect

2-((4-(1-((11)C)Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)-quinoline

C25H20N4O (392.163703)

C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor

Reglitazar

4-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-1,2-oxazolidine-3,5-dione

C22H20N2O5 (392.137215)

C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C154291 - Peroxisome Proliferator-Activated Receptor Agonist

2-[1-[(2S)-2-[[4-[(E)-N'-Hydroxycarbamimidoyl]benzoyl]amino]propanoyl]piperidin-4-yl]oxyacetic acid

2-[1-[(2S)-2-[[4-[(E)-N-Hydroxycarbamimidoyl]benzoyl]amino]propanoyl]piperidin-4-yl]oxyacetic acid

C18H24N4O6 (392.1695764)

2,6-Dioxo-9-phenyl-1,3-dipropylpurine-8-sulfonic acid

2,6-Dioxo-9-phenyl-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purine-8-sulphonic acid

C17H20N4O5S (392.11543500000005)

Shanzhiside

(1S,4AS,5R,7S,7as)-5,7-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-4-carboxylate

C16H24O11 (392.13185539999995)

Vellein

Salvifoliolide

C20H24O8 (392.1471104)

Cachineside IV

C16H24O11 (392.13185539999995)

Chiridquitoxin

C13H20N4O10 (392.117938)

Peroxyeupahakonin A

C20H24O8 (392.1471104)

Padiaxanthone

Brasilixanthone B

(7aS,10S,10aR)-10-(Acetyloxy)-7a,9,10,10a-tetrahydro-9,9-dimethyl-2-phenyl-4H-furo[3,2:4,5]furo[2,3-h]-1-benzopyran-4-one

C23H20O6 (392.125982)

Stachyoidin

(8aR,11aR) -rel- (-) -8a,11a-Dihydro-5-methoxy-10,10-dimethyl-2-phenyl-4H,8H-furo [ 3,2-d ] benzo [ 1,2-b:3,4-b ] dipyran-4,11 (10H) -dione

C23H20O6 (392.125982)

Hookerianin

8- (2,5-Dihydro-5,5-dimethyl-2-oxo-3-furanyl) -5,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one

C23H20O6 (392.125982)

Dehydrodeguelin

17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.0^{3,12.0^{4,9.0^{15,20]docosa-1(14),3(12),4(9),5,10,15,17,19-octaen-13-one

C23H20O6 (392.125982)

Dehydrodeguelin,7a,13a-Didehydrodeguelin is a member of rotenones. Dehydrodeguelin is a natural product found in Tephrosia vogelii, Derris montana, and other organisms with data available.

Mesuol

2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-4-phenyl-

C24H24O5 (392.1623654)

Mesuol is a neoflavonoid. Mesuol is a natural product found in Mesua ferrea and Mammea siamensis with data available.

anguvetin