cloprednol (BioDeep_00000831232)
代谢物信息卡片
化学式: C21H25ClO5 (392.139)
中文名称: 氯丁泼尼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CC(C3C(C1CCC2(C(=O)CO)O)C=C(C4=CC(=O)C=CC34C)Cl)O
InChI: InChI=1S/C21H25ClO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7-8,12-13,16,18,23,25,27H,4,6,9-10H2,1-2H3/t12-,13-,16-,18+,19-,20-,21-/m0/s1
描述信息
H - Systemic hormonal preparations, excl. sex hormones and insulins > H02 - Corticosteroids for systemic use > H02A - Corticosteroids for systemic use, plain > H02AB - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:135619
- KEGGdrug: D03561
- PubChem: 5284535
- DrugBank: DB13843
- ChEMBL: CHEMBL1697832
- CAS: 5251-34-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- H Möllmann, G Hochhaus, S Rohatagi, J Barth, H Derendorf, M Krieg, H Weisser, A C Möllmann. Pharmacokinetics and pharmacodynamics of cloprednol.
International journal of clinical pharmacology and therapeutics.
1996 Jan; 34(1):1-5. doi:
NULL
. [PMID: 8688990] - U F Legler. Pharmacokinetics of cloprednol in healthy volunteers.
International journal of clinical pharmacology, therapy, and toxicology.
1988 Apr; 26(4):173-5. doi:
NULL
. [PMID: 3403094] - R V Tomlinson, R Runkel, M D Chaplin, L Bowen, J Kanagy, N Chu. In vitro studies on the binding of cloprednol to human plasma proteins.
Journal of steroid biochemistry.
1982 Jan; 16(1):75-80. doi:
10.1016/0022-4731(82)90146-7
. [PMID: 7062742] - C Lee, B Amos, S B Matin. High-performance liquid chromatographic measurement of cloprednol in human plasma.
Journal of pharmaceutical sciences.
1981 Jun; 70(6):669-72. doi:
10.1002/jps.2600700624
. [PMID: 7252813] - U D Gavani, J S Hyde, S Khurana, L M Manaligod. Long-term cloprednol use in chronic asthma.
JAMA.
1979 Dec; 242(24):2679-82. doi:
NULL
. [PMID: 501863] - E F Ellis, H G Morris, F Kiechel, J D Pollock, L J Strand. Short-term efficacy and side effects of cloprednol in children with asthma.
Journal of clinical pharmacology.
1979 Oct; 19(10):675-83. doi:
10.1002/j.1552-4604.1979.tb01631.x
. [PMID: 512064] - G Miskovits, J P Rado, A Toth, E Zolnay. Efficacy, safety and hypothalamic-pituitary-adrenal axis function in patients with asthma treated with cloprednol.
Respiration; international review of thoracic diseases.
1979; 38(6):345-52. doi:
10.1159/000194101
. [PMID: 231809] - E J Mroszczak, R Runkel, L J Strand, R V Tomlinson, A Fratis, E Segre. Cloprednol bioavailability in humans.
Journal of pharmaceutical sciences.
1978 Jul; 67(7):920-3. doi:
10.1002/jps.2600670712
. [PMID: 660508] - E Ortega, C Rodriguez, L J Strand, S Bessler, E Segre. Metabolic effects of cloprednol-a new systemic corticosteroid.
Journal of clinical pharmacology.
1976 Feb; 16(2-3):122-8. doi:
10.1002/j.1552-4604.1976.tb02393.x
. [PMID: 1254734]