Exact Mass: 371.0753

Exact Mass Matches: 371.0753

Found 211 metabolites which its exact mass value is equals to given mass value 371.0753, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Nedocromil

9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid

C19H17NO7 (371.1005)


Nedocromil is only found in individuals that have used or taken this drug. It is a pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets. [PubChem]Nedocromil has been shown to inhibit the in vitro activation of, and mediator release from, a variety of inflammatory cell types associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets. Nedocromil inhibits activation and release of inflammatory mediators such as histamine, prostaglandin D2 and leukotrienes c4 from different types of cells in the lumen and mucosa of the bronchial tree. These mediators are derived from arachidonic acid metabolism through the lipoxygenase and cyclo-oxygenase pathways. The mechanism of action of nedocromil may be due partly to inhibition of axon reflexes and release of sensory neuropeptides, such as substance P, neurokinin A, and calcitonin-geneñrelated peptides. The result is inhibition of bradykinin-induced bronchoconstriction. Nedocromil does not posess any bronchodilator, antihistamine, or corticosteroid activity. R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BC - Antiallergic agents, excl. corticosteroids R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AC - Antiallergic agents, excl. corticosteroids S - Sensory organs > S01 - Ophthalmologicals > S01G - Decongestants and antiallergics C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D000893 - Anti-Inflammatory Agents > D000082142 - Mast Cell Stabilizers D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents D018926 - Anti-Allergic Agents D007155 - Immunologic Factors Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).

   

Sipatrigine

4-Amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine

C15H16Cl3N5 (371.0471)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents C26170 - Protective Agent > C1509 - Neuroprotective Agent D049990 - Membrane Transport Modulators D020011 - Protective Agents

   

S-sulfinatoglutathione

glutathione S-sulfinate

C10H17N3O8S2 (371.0457)


   

Arotinolol

5-(2-((3-(tert-Butylamino)-2-hydroxypropyl)thio)thiazol-4-yl)thiophene-2-carboxamide

C15H21N3O2S3 (371.0796)


C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker[1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites[2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases[1].

   

Berberine chloride

Berberine hydrochloride

C20H18NO4. Cl (371.0924)


Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1]. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

   

Ampicillin sodium

Ampicillin sodium

C16H18N3O4S. Na (371.0916)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic Same as: D02119

   

Carboplatin

7,7-diamino-6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione

C6H12N2O4Pt (371.0445)


Carboplatin is only found in individuals that have used or taken this drug. It is an organoplatinum compound that possesses antineoplastic activity. [PubChem]Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their attempts to replace the alkylated bases, preventing DNA synthesis and RNA transcription from the affected DNA, 2) DNA damage via the formation of cross-links (bonds between atoms in the DNA) which prevents DNA from being separated for synthesis or transcription, and 3) the induction of mispairing of the nucleotides leading to mutations. D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent > C1450 - Platinum Compound D000970 - Antineoplastic Agents

   

4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside

4-(2-amino-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-4-oxobutanoic acid

C16H21NO9 (371.1216)


4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside, also known as 4-AHPh-oba-glu, is classified as a member of the Phenolic glycosides. Phenolic glycosides are organic compounds containing a phenolic structure attached to a glycosyl moiety. Some examples of phenolic structures include lignans, and flavonoids. Among the sugar units found in natural glycosides are D-glucose, L-Fructose, and L rhamnose. 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside is considered to be slightly soluble (in water) and acidic

   

Salicyluric beta-D-glucuronide

(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({2-[(2-hydroxyphenyl)formamido]acetyl}oxy)oxane-2-carboxylic acid

C15H17NO10 (371.0852)


Salicyluric beta-D-glucuronide, also known as 1-O-salicyluroyl-beta-D-glucuronate or 1-O-[N-(2-hydroxybenzoyl)glycyl]-beta-D-glucronate, is a member of the class of compounds known as O-glucuronides. O-glucuronides are glucuronides in which the aglycone is linked to the carbohydrate unit through an O-glycosidic bond.

   

N,N-Bis(2-chloroethyl)-N',N'-diphenylphosphoric triamide

N,N-Bis(2-chloroethyl)-N,N-diphenylphosphoric triamide

C16H20Cl2N3OP (371.0721)


   

4-Dedimethylamino sancycline

1,10,11,12a-tetrahydroxy-3,12-dioxo-3,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboxamide

C19H17NO7 (371.1005)


   

Abt-751

N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzene-1-sulphonamide

C18H17N3O4S (371.094)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent

   

Arotinolol

5-(2-{[3-(tert-butylamino)-2-hydroxypropyl]sulphanyl}-1,3-thiazol-4-yl)thiophene-2-carboxamide

C15H21N3O2S3 (371.0796)


   

Azaribine

[3,4-bis(acetyloxy)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)oxolan-2-yl]methyl acetate

C14H17N3O9 (371.0965)


   

Baricitinib

2-[1-(Ethanesulphonyl)-3-(4-{1h-pyrrolo[2,3-D]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile

C16H17N7O2S (371.1164)


L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants > L04AA - Selective immunosuppressants C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials, DrugBank C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C172200 - JAK Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

PYR-41

Ethyl 4-{4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoic acid

C17H13N3O7 (371.0753)


   

Triaminophenyl phosphate

Tris(4-aminophenyl) phosphoric acid

C18H18N3O4P (371.1035)


   

Hydroxydesmethylpiperine sulfate

{2-hydroxy-5-[(1E)-5-(4-hydroxypiperidin-1-yl)-5-oxopent-1-en-1-yl]phenyl}oxidanesulphonic acid

C16H21NO7S (371.1039)


   

1ST40203A

16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride

C20H18ClNO4 (371.0924)


Berberine chloride (TN) is an organic molecular entity. Berberine Chloride is the orally bioavailable, hydrochloride salt form of berberine, a quaternary ammonium salt of an isoquinoline alkaloid and active component of various Chinese herbs, with potential antineoplastic, radiosensitizing, anti-inflammatory, anti-lipidemic and antidiabetic activities. Although the mechanisms of action through which berberine exerts its effects are not yet fully elucidated, upon administration this agent appears to suppress the activation of various proteins and/or modulate the expression of a variety of genes involved in tumorigenesis and inflammation, including, but not limited to transcription factor nuclear factor-kappa B (NF-kB), myeloid cell leukemia 1 (Mcl-1), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), cyclooxygenase (COX)-2, tumor necrosis factor (TNF), interleukin (IL)-6, IL-12, inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), E-selectin, monocyte chemoattractant protein-1 (MCP-1), C-X-C motif chemokine 2 (CXCL2), cyclin D1, activator protein (AP-1), hypoxia-inducible factor 1 (HIF-1), signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR), arylamine N-acetyltransferase (NAT), and DNA topoisomerase I and II. The modulation of gene expression may induce cell cycle arrest and apoptosis, and inhibit cancer cell proliferation. In addition, berberine modulates lipid and glucose metabolism. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1]. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

   
   
   
   
   

N-(3-Cyano-1H-indol-5-yl)-3-[4-(trifluoromethoxy)phenyl]acrylamide

N-(3-Cyano-1H-indol-5-yl)-3-[4-(trifluoromethoxy)phenyl]acrylamide

C19H12F3N3O2 (371.0882)


   
   
   
   

Antibiotic M 53B1

Antibiotic M 53B1

C14H17N3O7S (371.0787)


   

SCHEMBL12714883

SCHEMBL12714883

C17H17N5O5 (371.123)


   
   

3-{3-[2-hydroxybut-3-en-1-yl]-1,2,4-thiadiazol-5-yl}-5,6-dihydrospiro[indoline-3,2-thiopyran]-2-one

3-{3-[2-hydroxybut-3-en-1-yl]-1,2,4-thiadiazol-5-yl}-5,6-dihydrospiro[indoline-3,2-thiopyran]-2-one

C18H17N3O2S2 (371.0762)


   
   
   
   
   
   

Epiberberine chloride

16,17-dimethoxy-5,7-dioxa-1-azoniapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),2,4(8),9,11,14,16,18-octaene;chloride

C20H18ClNO4 (371.0924)


Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease[1]. Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways[2]. Epiberberine has the potential effect in the research of diabetic disease[3]. Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease[1]. Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways[2]. Epiberberine has the potential effect in the research of diabetic disease[3].

   

Berberine chloride

Berberine chloride

C20H18ClNO4 (371.0924)


   
   
   
   
   
   
   
   
   
   
   

Zalcitabine diphosphate

Zalcitabine diphosphate

C9H15N3O9P2 (371.0284)


   
   

Asn-Met-OH

(S)-2-(3-(2-amino-2-oxoethoxy)-4-nitrobenzamido)-5-(methylthio)pentanoic acid

C14H17N3O7S (371.0787)


   

Met-Asn-OH

(S)-5-amino-2-(3-(2-(methylthio)ethoxy)-4-nitrobenzamido)-5-oxopentanoic acid

C14H17N3O7S (371.0787)


   

camazepam

camazepam

C19H18ClN3O3 (371.1037)


N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics > N05BA - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent

   

4-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxybutyl nitrate

4-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxybutyl nitrate

C19H17NO7 (371.1005)


   

3-hydroxy-4-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]pentanoic acid

3-hydroxy-4-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]pentanoic acid

C17H16F3NO5 (371.0981)


   

methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate

methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate

C20H18ClNO4 (371.0924)


   

(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C12H13N5O5S2 (371.0358)


   

(4-(3-CHLOROPHENYLAMINO)-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDIN-7-YL)(MORPHOLINO)METHANONE

(4-(3-CHLOROPHENYLAMINO)-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDIN-7-YL)(MORPHOLINO)METHANONE

C18H18ClN5O2 (371.1149)


   

3-[[2-[4-(2-phenylethynyl)phenoxy]acetyl]amino]benzoic acid

3-[[2-[4-(2-phenylethynyl)phenoxy]acetyl]amino]benzoic acid

C23H17NO4 (371.1158)


   

1-benzamido-4-(diazonioamino)-2,5-dimethoxybenzene,tetrafluoroborate

1-benzamido-4-(diazonioamino)-2,5-dimethoxybenzene,tetrafluoroborate

C15H14BF4N3O3 (371.1064)


   

N,N,N,N-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

N,N,N,N-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

C10H16F6N3OPS (371.0656)


   
   

2-N-BOC-3-(3-BROMO-PHENYL)-2-METHYLAMINOMETHYL-PROPIONIC ACID

2-N-BOC-3-(3-BROMO-PHENYL)-2-METHYLAMINOMETHYL-PROPIONIC ACID

C16H22BrNO4 (371.0732)


   

4-(4,6-bis(2-hydroxyethoxy)-1,3,5-triazin-2-ylamino)benzenesulfonamide

4-(4,6-bis(2-hydroxyethoxy)-1,3,5-triazin-2-ylamino)benzenesulfonamide

C13H17N5O6S (371.09)


   

n-bsmoc-l-methionine

n-bsmoc-l-methionine

C15H17NO6S2 (371.0497)


   
   

N-(2,4-DIMETHYLPHENYL)-3-(PHOSPHONOOXY)-2-NAPHTHALENECARBOXAMIDE

N-(2,4-DIMETHYLPHENYL)-3-(PHOSPHONOOXY)-2-NAPHTHALENECARBOXAMIDE

C19H18NO5P (371.0923)


   

3-Bromo-9-(1-naphthyl)-9H-carbazole

3-Bromo-9-(1-naphthyl)-9H-carbazole

C22H14BrN (371.031)


   

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide,dihydrochloride

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide,dihydrochloride

C14H24Cl3N3O2 (371.0934)


   

Benzyl (S)-3-(Boc-amino)-4-bromobutanoate

Benzyl (S)-3-(Boc-amino)-4-bromobutanoate

C16H22BrNO4 (371.0732)


   

2-N-BOC-3-(4-BROMO-PHENYL)-2-METHYLAMINOMETHYL-PROPIONIC ACID

2-N-BOC-3-(4-BROMO-PHENYL)-2-METHYLAMINOMETHYL-PROPIONIC ACID

C16H22BrNO4 (371.0732)


   

6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE

6-[[2-(1-METHYLETHYL)PHENYL]]SULFONYL-5-NITRO-8-QUINOLINAMINE

C18H17N3O4S (371.094)


   

N-((4-NITROPHENYL)SULFONYL)-1-(TERT-BUTYLOXYCARBONYL)PIPERAZINE

N-((4-NITROPHENYL)SULFONYL)-1-(TERT-BUTYLOXYCARBONYL)PIPERAZINE

C15H21N3O6S (371.1151)


   

n6-benzoyl-8-hydroxy-2-deoxyadenosine

n6-benzoyl-8-hydroxy-2-deoxyadenosine

C17H17N5O5 (371.123)


   

Berberine (chloride hydrate)

Berberine (chloride hydrate)

C20H18ClNO4 (371.0924)


   

1-{4-[3,5-DI(TRIFLUOROMETHYL)PHENOXY]PHENYL}-1H-PYRROLE

1-{4-[3,5-DI(TRIFLUOROMETHYL)PHENOXY]PHENYL}-1H-PYRROLE

C18H11F6NO (371.0745)


   

TERT-BUTYL 4-((4-BROMOPHENYL)THIO)PIPERIDINE-1-CARBOXYLATE

TERT-BUTYL 4-((4-BROMOPHENYL)THIO)PIPERIDINE-1-CARBOXYLATE

C16H22BrNO2S (371.0555)


   

N6-Benzoyladenosine

N6-Benzoyladenosine

C17H17N5O5 (371.123)


   

5-O-BENZOYL-3-AZIDO-3-DEOXYTHYMIDINE

5-O-BENZOYL-3-AZIDO-3-DEOXYTHYMIDINE

C17H17N5O5 (371.123)


   

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane

C15H18INO2 (371.0382)


   

METHYL 2-N-BOC-2-AMINOMETHYL-3-(3-BROMO-PHENYL)-PROPIONATE

METHYL 2-N-BOC-2-AMINOMETHYL-3-(3-BROMO-PHENYL)-PROPIONATE

C16H22BrNO4 (371.0732)


   

Ethyl 8-benzyl-5-hydroxy-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate

Ethyl 8-benzyl-5-hydroxy-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate

C18H17N3O4S (371.094)


   

1H-1,3,4-Benzotriazepine,2-(2-thienyl)-5-[4-(trifluoromethyl)phenyl]-(9CI)

1H-1,3,4-Benzotriazepine,2-(2-thienyl)-5-[4-(trifluoromethyl)phenyl]-(9CI)

C19H12F3N3S (371.0704)


   

Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate

Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate

C17H23Cl2N3O2 (371.1167)


   

METHYL 2-N-BOC-2-AMINOMETHYL-3-(4-BROMO-PHENYL)-PROPIONATE

METHYL 2-N-BOC-2-AMINOMETHYL-3-(4-BROMO-PHENYL)-PROPIONATE

C16H22BrNO4 (371.0732)


   

1-[(1,3,4-trimethyl-4,5-dihydroimidazol-1-ium-2-yl)oxy]pyrrolidine-2,5-dione,hexafluorophosphate

1-[(1,3,4-trimethyl-4,5-dihydroimidazol-1-ium-2-yl)oxy]pyrrolidine-2,5-dione,hexafluorophosphate

C10H16F6N3O3P (371.0833)


   

Azaribine

6-AZAURIDINE 2,3,5-TRIACETATE

C14H17N3O9 (371.0965)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite C471 - Enzyme Inhibitor > C2170 - Orotidylate Decarboxylase Inhibitor D003879 - Dermatologic Agents Azaribine (2',3',5'-Tri-O-acetyl-6-azauridine) is a potent orotidine monophosphate decarboxylase (OMPD) inhibitor. Azaribine is an antiviral inhibitor of several RNA viruses and inhibits viral genome replication and gene transcription. Azaribine shows broad-spectrum antiviral activity (EC50=3.80?nM-1.73?μM against influenza A and B viruses; EC50=1.62 μM against ZIKV Paraiba). Azaribine, a triacetate salt of Azauridine, has the potential for psoriasis research[1][2].

   

9-(2-Naphthyl)-3-bromocarbazole

9-(2-Naphthyl)-3-bromocarbazole

C22H14BrN (371.031)


   

Fmoc-cys(et)-oh

Fmoc-cys(et)-oh

C20H21NO4S (371.1191)


   
   

O-Succinimidyl-1,3-dimethylpropyleneuronium hexafluorophosphate

O-Succinimidyl-1,3-dimethylpropyleneuronium hexafluorophosphate

C10H16N3O3.PF6 (371.0833)


   

2-Bromo-9-(2-naphthyl)-9H-carbazole

2-Bromo-9-(2-naphthyl)-9H-carbazole

C22H14BrN (371.031)


   

3-QUINOLINECARBOXYLIC ACID, 4-CHLORO-6-METHOXY-7-(PHENYLMETHOXY)-, ETHYL ESTER

3-QUINOLINECARBOXYLIC ACID, 4-CHLORO-6-METHOXY-7-(PHENYLMETHOXY)-, ETHYL ESTER

C20H18ClNO4 (371.0924)


   

2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl benzoate

2-[(2-Acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl benzoate

C17H17N5O5 (371.123)


   

tert-butyl 4-broMo-2-fluorobenzyl(cyclopentyl)carbaMate

tert-butyl 4-broMo-2-fluorobenzyl(cyclopentyl)carbaMate

C17H23BrFNO2 (371.0896)


   

tert-butyl 4-broMo-3-fluorobenzyl(cyclopentyl)carbaMate

tert-butyl 4-broMo-3-fluorobenzyl(cyclopentyl)carbaMate

C17H23BrFNO2 (371.0896)


   

5-Bromo-4-chloro-3-indolyl caprylate

5-Bromo-4-chloro-3-indolyl caprylate

C16H19BrClNO2 (371.0288)


   

5-Bromo-6-chloro-1H-indol-3-yl octanoate

5-Bromo-6-chloro-1H-indol-3-yl octanoate

C16H19BrClNO2 (371.0288)


   
   

5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole

5-(Difluoromethoxy)-2[[(4-chloro-3-methoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole

C15H12ClF2N3O2S (371.0307)


   

6-methylheptoxycarbonylmethanethiolate: trimethyltin

6-methylheptoxycarbonylmethanethiolate: trimethyltin

C13H31O2SSn (371.1067)


   

N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide

N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide

C20H12ClF2NO2 (371.0525)


   

Incyclinide

Incyclinide

C19H17NO7 (371.1005)


C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C1970 - Matrix Metalloproteinase Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor

   

4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic Acid

4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic Acid

C21H13N3O4 (371.0906)


   

Ampicillin sodium

Ampicillin sodium

C16H18N3NaO4S (371.0916)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

   

Denotivir

Denotivir

C18H14ClN3O2S (371.0495)


C254 - Anti-Infective Agent > C281 - Antiviral Agent

   

5-Dimethylarsinoyladenosine

5-Dimethylarsinoyladenosine

C12H18AsN5O4 (371.0575)


   
   

Triaminophenyl phosphate

Triaminophenyl phosphate

C18H18N3O4P (371.1035)


   

8-Hydroxy-pipat

8-Hydroxy-pipat

C16H22INO (371.0746)


   

2-(3-Pyridinyl)-4-[4-(1-pyrrolidinylsulfonyl)phenyl]thiazole

2-(3-Pyridinyl)-4-[4-(1-pyrrolidinylsulfonyl)phenyl]thiazole

C18H17N3O2S2 (371.0762)


   

Remdesivir nucleoside monophosphate

Remdesivir nucleoside monophosphate

C12H14N5O7P (371.0631)


COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]acetamide

N-[6-acetyl-3-(1,3-benzothiazol-2-yl)-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]acetamide

C18H17N3O2S2 (371.0762)


   

7-hydroxy-PIPAT

7-hydroxy-PIPAT

C16H22INO (371.0746)


   

N-[4-[[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide

N-[4-[[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide

C17H13N3O3S2 (371.0398)


   

3-{[(3-Fluoro-3-Methoxybiphenyl-4-Yl)amino]carbonyl}thiophene-2-Carboxylic Acid

3-{[(3-Fluoro-3-Methoxybiphenyl-4-Yl)amino]carbonyl}thiophene-2-Carboxylic Acid

C19H14FNO4S (371.0628)


   

N-(4-Acetylphenyl)-5-(5-chloro-2,4-dihydroxyphenyl)-1H-pyrazole-4-carboxamide

N-(4-Acetylphenyl)-5-(5-chloro-2,4-dihydroxyphenyl)-1H-pyrazole-4-carboxamide

C18H14ClN3O4 (371.0673)


   

2-(Cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate

2-(Cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate

C16H21NO5S2 (371.0861)


   

Baricitinib

Baricitinib

C16H17N7O2S (371.1164)


L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants > L04AA - Selective immunosuppressants C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials, DrugBank C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C172200 - JAK Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

(-)-Dehydrodiconiferyl acid

(-)-Dehydrodiconiferyl acid

C20H19O7- (371.1131)


   

(+)-Dehydrodiconiferyl acid

(+)-Dehydrodiconiferyl acid

C20H19O7- (371.1131)


   

Tyrosine-betaxanthin

Tyrosine-betaxanthin

C18H15N2O7-3 (371.0879)


   

Dehydrodiconiferyl acid

Dehydrodiconiferyl acid

C20H19O7- (371.1131)


   

[(2R,3S,4R,5S)-5-(4-amino-5-cyanopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

[(2R,3S,4R,5S)-5-(4-amino-5-cyanopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

C12H14N5O7P (371.0631)


   

Hydroxydesmethylpiperine sulfate

Hydroxydesmethylpiperine sulfate

C16H21NO7S (371.1039)


   

Paraplatin

Carboplatin

C6H12N2O4Pt (371.0445)


L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XA - Platinum compounds D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents D000970 - Antineoplastic Agents

   
   

(S)-averantin(1-)

(S)-averantin(1-)

C20H19O7- (371.1131)


A phenolate anion obtained by deprotonation of the 2-hydroxy group of (S)-averantin. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).

   

7-Benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl ester

7-Benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl ester

C19H14ClNO5 (371.056)


   

5-[[2,3-Dihydro-1,4-benzodioxin-3-yl(oxo)methyl]amino]benzene-1,3-dicarboxylic acid dimethyl ester

5-[[2,3-Dihydro-1,4-benzodioxin-3-yl(oxo)methyl]amino]benzene-1,3-dicarboxylic acid dimethyl ester

C19H17NO7 (371.1005)


   

(5Z)-3-hexyl-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

(5Z)-3-hexyl-5-[(5-phenyl-1H-pyrazol-4-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

C19H21N3OS2 (371.1126)


   

2-(2,5-dichlorophenyl)sulfonyl-N-methyl-N-[(2-methylphenyl)methyl]ethanamine

2-(2,5-dichlorophenyl)sulfonyl-N-methyl-N-[(2-methylphenyl)methyl]ethanamine

C17H19Cl2NO2S (371.0513)


   

4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione

4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione

C18H17N3O4S (371.094)


   

4-[5-Amino-3-methyl-4-[oxo-[3-(trifluoromethyl)phenyl]methyl]-2-thiophenyl]butanoic acid

4-[5-Amino-3-methyl-4-[oxo-[3-(trifluoromethyl)phenyl]methyl]-2-thiophenyl]butanoic acid

C17H16F3NO3S (371.0803)


   

3-{[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(2-methoxyphenyl)propanamide

3-{[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(2-methoxyphenyl)propanamide

C18H17N3O4S (371.094)


   

1-(2-Methoxyethyl)-7-thiophen-2-yl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4-dione

1-(2-Methoxyethyl)-7-thiophen-2-yl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4-dione

C15H12F3N3O3S (371.0551)


   

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(6-methoxy-1H-benzimidazol-2-yl)thio]acetamide

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(6-methoxy-1H-benzimidazol-2-yl)thio]acetamide

C18H17N3O4S (371.094)


   

N-(1,3-benzothiazol-2-yl)-2-[(E)-(3,4-dimethoxyphenyl)methylideneamino]oxyacetamide

N-(1,3-benzothiazol-2-yl)-2-[(E)-(3,4-dimethoxyphenyl)methylideneamino]oxyacetamide

C18H17N3O4S (371.094)


   

3-(1,3-benzothiazol-2-ylsulfanyl)-N-[(E)-(4-methoxyphenyl)methylideneamino]propanamide

3-(1,3-benzothiazol-2-ylsulfanyl)-N-[(E)-(4-methoxyphenyl)methylideneamino]propanamide

C18H17N3O2S2 (371.0762)


   

Herqueinone(1-)

Herqueinone(1-)

C20H19O7- (371.1131)


   

4-[(1-Methyl-5-tetrazolyl)thio]-5-(4-nitrophenyl)thieno[2,3-d]pyrimidine

4-[(1-Methyl-5-tetrazolyl)thio]-5-(4-nitrophenyl)thieno[2,3-d]pyrimidine

C14H9N7O2S2 (371.0259)


   

N-[(8-methoxy-5-nitro-7-quinolinyl)-thiophen-2-ylmethyl]propanamide

N-[(8-methoxy-5-nitro-7-quinolinyl)-thiophen-2-ylmethyl]propanamide

C18H17N3O4S (371.094)


   

(4aS,5aR,12aS)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide

(4aS,5aR,12aS)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide

C19H17NO7 (371.1005)


   
   

ethyl 4-{(4E)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

ethyl 4-{(4E)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

C17H13N3O7 (371.0753)


   

2-[(2S,3R,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2S,3R,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

methyl 2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

methyl 2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

C16H21NO7S (371.1039)


   

methyl 2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

methyl 2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

C16H21NO7S (371.1039)


   

methyl 2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

methyl 2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-3-yl]acetate

C16H21NO7S (371.1039)


   

(2R,3S)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2R,3S)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2R,3R)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2R,3R)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2S,3R)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2S,3R)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

2-[(2R,3S,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2R,3S,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(2R,3R,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2R,3R,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

2-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

(2R,3S)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2R,3S)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2S,3R)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2S,3R)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2S,3S)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2S,3S)-8-bromo-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2R,3R)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2R,3R)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

(2S,3S)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

(2S,3S)-8-bromo-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-6-one

C15H22BrN3O3 (371.0844)


   

2-[(2R,3S,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2R,3S,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(2S,3R,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2S,3R,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(2S,3S,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2S,3S,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(2S,3S,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2S,3S,6S)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(2R,3R,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

2-[(2R,3R,6R)-2-(hydroxymethyl)-3-[(4-methoxyphenyl)sulfonylamino]-3,6-dihydro-2H-pyran-6-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

2-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

2-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   

2-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

2-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-6-(methanesulfonamido)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester

C16H21NO7S (371.1039)


   
   
   
   
   
   
   
   

N-(5-(3-Methoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-YL)-isonicotinamide

N-(5-(3-Methoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-YL)-isonicotinamide

C17H13N3O3S2 (371.0398)


   

(2E)-2-[(E)-benzylidenehydrazinylidene]-5,5-diphenyl-1,3-thiazolidin-4-one

(2E)-2-[(E)-benzylidenehydrazinylidene]-5,5-diphenyl-1,3-thiazolidin-4-one

C22H17N3OS (371.1092)


   

(4S)-2-(1,3-benzothiazol-2-yl)-5-methyl-4-(naphthalen-1-ylmethyl)-4H-pyrazol-3-one

(4S)-2-(1,3-benzothiazol-2-yl)-5-methyl-4-(naphthalen-1-ylmethyl)-4H-pyrazol-3-one

C22H17N3OS (371.1092)


   

2-Amino-3-[2,3-di(propanoyloxy)propoxy-hydroxyphosphoryl]oxypropanoic acid

2-Amino-3-[2,3-di(propanoyloxy)propoxy-hydroxyphosphoryl]oxypropanoic acid

C12H22NO10P (371.0981)


   
   
   
   

3-[(3-Acetyloxy-2-butanoyloxypropoxy)-hydroxyphosphoryl]oxy-2-aminopropanoic acid

3-[(3-Acetyloxy-2-butanoyloxypropoxy)-hydroxyphosphoryl]oxy-2-aminopropanoic acid

C12H22NO10P (371.0981)


   

Berberinum

16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride

C20H18NO4. Cl (371.0924)


Berberine chloride (TN) is an organic molecular entity. Berberine Chloride is the orally bioavailable, hydrochloride salt form of berberine, a quaternary ammonium salt of an isoquinoline alkaloid and active component of various Chinese herbs, with potential antineoplastic, radiosensitizing, anti-inflammatory, anti-lipidemic and antidiabetic activities. Although the mechanisms of action through which berberine exerts its effects are not yet fully elucidated, upon administration this agent appears to suppress the activation of various proteins and/or modulate the expression of a variety of genes involved in tumorigenesis and inflammation, including, but not limited to transcription factor nuclear factor-kappa B (NF-kB), myeloid cell leukemia 1 (Mcl-1), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), cyclooxygenase (COX)-2, tumor necrosis factor (TNF), interleukin (IL)-6, IL-12, inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), E-selectin, monocyte chemoattractant protein-1 (MCP-1), C-X-C motif chemokine 2 (CXCL2), cyclin D1, activator protein (AP-1), hypoxia-inducible factor 1 (HIF-1), signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR), arylamine N-acetyltransferase (NAT), and DNA topoisomerase I and II. The modulation of gene expression may induce cell cycle arrest and apoptosis, and inhibit cancer cell proliferation. In addition, berberine modulates lipid and glucose metabolism. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1]. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

   

NEDOCROMIL

NEDOCROMIL

C19H17NO7 (371.1005)


R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03B - Other drugs for obstructive airway diseases, inhalants > R03BC - Antiallergic agents, excl. corticosteroids R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AC - Antiallergic agents, excl. corticosteroids S - Sensory organs > S01 - Ophthalmologicals > S01G - Decongestants and antiallergics C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D000893 - Anti-Inflammatory Agents > D000082142 - Mast Cell Stabilizers D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents D018926 - Anti-Allergic Agents D007155 - Immunologic Factors Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).

   

glutathione S-sulfinate

glutathione S-sulfinate

C10H17N3O8S2 (371.0457)


   

Abt-751

ABT-751 (E7010)

C18H17N3O4S (371.094)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent

   

ent-glycosmisate

ent-glycosmisate

C20H19O7 (371.1131)


A monocarboxylic acid anion that is the conjugate base of ent-glycosmisic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.

   

BW619c89

Sipatrigine

C15H16Cl3N5 (371.0471)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents C26170 - Protective Agent > C1509 - Neuroprotective Agent D049990 - Membrane Transport Modulators D020011 - Protective Agents

   

4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside

4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside

C16H21NO9 (371.1216)


   

Salicyluric beta-D-glucuronide

Salicyluric beta-D-glucuronide

C15H17NO10 (371.0852)


   

GS-441524 monophosphate

GS-441524 monophosphate

C12H14N5O7P (371.0631)


A C-nucleoside phosphate that is GS-441524 in which the 5-hydroxy group has been replaced by a phosphate group. In cells, GS-441524 monophosphate gets converted into the pharmacologically active triphosphate form (GS-443902).

   

glycosmisate

glycosmisate

C20H19O7 (371.1131)


A monocarboxylic acid anion that is the conjugate base of glycosmisic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.

   
   

AS1949490

AS1949490

C20H18ClNO2S (371.0747)


AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 μM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes[1][2].

   

Azemiglitazone

Azemiglitazone

C19H17NO5S (371.0827)


Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier (MPC), which inhibits Alzheimer’s disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury[4][5].

   

FITM

FITM

C18H18FN5OS (371.1216)


FITM is a negative allosteric modulator of mGlu1 receptor with a Ki of 2.5 nM.

   

Quinotolast sodium

Quinotolast sodium

C17H12N6NaO3 (371.0869)


Quinotolast sodium in the concentration range of 1-100 μg/mL inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner.

   

Z16078526

Z16078526

C18H17N3O4S (371.094)


Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse[1].

   

aristolochic acid iv

aristolochic acid iv

C18H13NO8 (371.0641)


   

5-hydroxy-3,4-bis(4-hydroxy-3-nitrophenyl)pyrrol-2-one

5-hydroxy-3,4-bis(4-hydroxy-3-nitrophenyl)pyrrol-2-one

C16H9N3O8 (371.039)


   

2-{[hydroxy(4,5,7-trihydroxy-9,10-dioxoanthracen-2-yl)methylidene]amino}propanoic acid

2-{[hydroxy(4,5,7-trihydroxy-9,10-dioxoanthracen-2-yl)methylidene]amino}propanoic acid

C18H13NO8 (371.0641)


   

2-(6-aminopurin-9-yl)-5-[(dimethylarsoryl)methyl]oxolane-3,4-diol

2-(6-aminopurin-9-yl)-5-[(dimethylarsoryl)methyl]oxolane-3,4-diol

C12H18AsN5O4 (371.0575)


   

7,8-dimethoxy-3,4-methylenedioxy-10-nitro-1-phenanthrenecarboxylic acid

NA

C18H13NO8 (371.0641)


{"Ingredient_id": "HBIN012987","Ingredient_name": "7,8-dimethoxy-3,4-methylenedioxy-10-nitro-1-phenanthrenecarboxylic acid","Alias": "NA","Ingredient_formula": "C18H13NO8","Ingredient_Smile": "NA","Ingredient_weight": "371.3","OB_score": "NA","CAS_id": "79185-74-3","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7476","PubChem_id": "NA","DrugBank_id": "NA"}

   

7-methoxy-aristolochiacacid

NA

C18H13NO8 (371.0641)


{"Ingredient_id": "HBIN013335","Ingredient_name": "7-methoxy-aristolochiacacid","Alias": "NA","Ingredient_formula": "C18H13NO8","Ingredient_Smile": "COC1=CC2=CC(=C3C(=CC4=C(C3=C2C=C1OC)OCO4)C(=O)O)[N+](=O)[O-]","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "13836","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}

   

7-methoxy-aristolochiac acid a

3,4-Methylenedioxy-7,8-dimethoxy-10-nitrophenanthrene-1-carboxylic acid; AC1NSY17; 7-methoxyaristolochic acid a; 79185-74-3; 8,9-dimethoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid

C18H13NO8 (371.0641)


{"Ingredient_id": "HBIN013336","Ingredient_name": "7-methoxy-aristolochiac acid a","Alias": "3,4-Methylenedioxy-7,8-dimethoxy-10-nitrophenanthrene-1-carboxylic acid; AC1NSY17; 7-methoxyaristolochic acid a; 79185-74-3; 8,9-dimethoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid","Ingredient_formula": "C18H13NO8","Ingredient_Smile": "COC1=CC=CC2=C1C(=C(C3=C2C4=C(C=C3C(=O)O)OCO4)[N+](=O)[O-])OC","Ingredient_weight": "371.3 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "SMIT19335","TCMID_id": "31525","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "46233015","DrugBank_id": "NA"}

   

aristolochicacid d methyl ether

NA

C18H13NO8 (371.0641)


{"Ingredient_id": "HBIN016804","Ingredient_name": "aristolochicacid d methyl ether","Alias": "NA","Ingredient_formula": "C18H13NO8","Ingredient_Smile": "COC1=CC2=C3C(=C(C=C2C(=C1)OC)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "1714","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}

   

(2s)-2-{[hydroxy(4,5,7-trihydroxy-9,10-dioxoanthracen-2-yl)methylidene]amino}propanoic acid

(2s)-2-{[hydroxy(4,5,7-trihydroxy-9,10-dioxoanthracen-2-yl)methylidene]amino}propanoic acid

C18H13NO8 (371.0641)


   

(3r)-3-hydroxy-3-methyl-4-(1,4,5-trihydroxy-9,10-dioxoanthracen-2-yl)butanimidic acid

(3r)-3-hydroxy-3-methyl-4-(1,4,5-trihydroxy-9,10-dioxoanthracen-2-yl)butanimidic acid

C19H17NO7 (371.1005)


   

(2r,3r,4s,5s)-2-(6-aminopurin-9-yl)-5-[(dimethylarsoryl)methyl]oxolane-3,4-diol

(2r,3r,4s,5s)-2-(6-aminopurin-9-yl)-5-[(dimethylarsoryl)methyl]oxolane-3,4-diol

C12H18AsN5O4 (371.0575)


   

methyl 3,4,8-trimethoxy-10-nitrophenanthrene-1-carboxylate

methyl 3,4,8-trimethoxy-10-nitrophenanthrene-1-carboxylate

C19H17NO7 (371.1005)