Carboplatin (BioDeep_00000033281)
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
7,7-diamino-6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione
化学式: C6H12N2O4Pt (371.0444882)
中文名称: 卡铂
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2]
InChI: /q
描述信息
Carboplatin is only found in individuals that have used or taken this drug. It is an organoplatinum compound that possesses antineoplastic activity. [PubChem]Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their attempts to replace the alkylated bases, preventing DNA synthesis and RNA transcription from the affected DNA, 2) DNA damage via the formation of cross-links (bonds between atoms in the DNA) which prevents DNA from being separated for synthesis or transcription, and 3) the induction of mispairing of the nucleotides leading to mutations.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent > C1450 - Platinum Compound
D000970 - Antineoplastic Agents
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:31355
- PubChem: 10339178
- HMDB: HMDB0015093
- Wikipedia: Carboplatin
- MeSH: Carboplatin
- chemspider: 8514637
- CAS: 41575-94-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lian Wang, Bing Xiong, Wei Lu, Yujie Cheng, Jihui Zhu, Guihai Ai, Xiaojie Zhang, Xiuni Liu, Zhongping Cheng. Senolytic drugs dasatinib and quercetin combined with Carboplatin or Olaparib reduced the peritoneal and adipose tissue metastasis of ovarian cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 May; 174(?):116474. doi:
10.1016/j.biopha.2024.116474. [PMID: 38518604] - Eman Jaradat, Adam Meziane, Dimitrios A Lamprou. Conventional vs PEGylated loaded liposomal formulations by microfluidics for delivering hydrophilic chemotherapy.
International journal of pharmaceutics.
2024 Apr; 655(?):124077. doi:
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Journal of translational medicine.
2024 Feb; 22(1):192. doi:
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Cellular and molecular biology (Noisy-le-Grand, France).
2023 Dec; 69(14):155-160. doi:
10.14715/cmb/2023.69.14.25. [PMID: 38279452] - Xinyu Hao, Ming Zu, Jing Ning, Xin Zhou, Yueqing Gong, Xiurui Han, Qiao Meng, Dong Li, Shigang Ding. Antitumor effect of luteolin proven by patient-derived organoids of gastric cancer.
Phytotherapy research : PTR.
2023 Jul; ?(?):. doi:
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European review for medical and pharmacological sciences.
2023 07; 27(13):6343-6350. doi:
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Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2023 06; 18(6):769-779. doi:
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PloS one.
2023; 18(10):e0287151. doi:
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Acta biochimica et biophysica Sinica.
2022 Dec; ?(?):. doi:
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Drug delivery.
2022 Dec; 29(1):1571-1581. doi:
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International journal of pharmaceutics.
2022 Oct; 626(?):122164. doi:
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Molecular nutrition & food research.
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Trials.
2022 Jul; 23(1):556. doi:
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Hemodialysis international. International Symposium on Home Hemodialysis.
2022 07; 26(3):E31-E36. doi:
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Medicine.
2022 Jun; 101(24):e28940. doi:
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International journal of molecular sciences.
2022 Jun; 23(11):. doi:
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Molecular biology reports.
2022 Jun; 49(6):4633-4641. doi:
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Cancer research.
2022 03; 82(6):1140-1152. doi:
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Experimental eye research.
2022 03; 216(?):108954. doi:
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European journal of cancer (Oxford, England : 1990).
2022 03; 163(?):88-97. doi:
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Targeted oncology.
2022 03; 17(2):141-151. doi:
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Cancer research.
2022 02; 82(4):665-680. doi:
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Hepatology international.
2022 Feb; 16(1):125-134. doi:
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Investigational new drugs.
2022 02; 40(1):106-114. doi:
10.1007/s10637-021-01155-w. [PMID: 34495421] - Ari J Rosenberg, Evgeny Izumchenko, Alexander Pearson, Zhen Gooi, Elizabeth Blair, Theodore Karrison, Aditya Juloori, Daniel Ginat, Nicole Cipriani, Mark Lingen, Hillary Sloane, Daniel L Edelstein, Kirsten Keyser, Johannes Fredebohm, Frank Holtrup, Frederick S Jones, Daniel Haraf, Nishant Agrawal, Everett E Vokes. Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment.
BMC cancer.
2022 Jan; 22(1):17. doi:
10.1186/s12885-021-09146-z. [PMID: 34980038] - Matthew J Murray, Rafael Moleron, Jennifer Adamski, Martin English, G A Amos Burke, Justin Cross, Thankamma Ajithkumar, Sara Stoneham, James C Nicholson. Vinblastine monotherapy induction prior to radiotherapy for patients with intracranial germinoma during the COVID-19 pandemic.
Pediatric blood & cancer.
2022 01; 69(1):e29359. doi:
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Gynecologic oncology.
2022 01; 164(1):136-145. doi:
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Nutrition and cancer.
2022; 74(4):1431-1445. doi:
10.1080/01635581.2021.1952453. [PMID: 34286635] - Beatriz Belda, José Ramos-Vara, Kristen M Messenger, Marije Risselada. Pharmacokinetic and safety assessment of carboplatin-impregnated calcium sulfate hemihydrate beads in eight rats.
Veterinary surgery : VS.
2021 Nov; 50(8):1650-1661. doi:
10.1111/vsu.13712. [PMID: 34375028] - Paulo D'Amora, Ismael Dale C G Silva, Krishnansu S Tewari, Robert E Bristow, Fabio Cappuccini, Steven S Evans, Marcia B Salzgeber, Paula J Addis-Bernard, Anton M Palma, Dirce M L Marchioni, Antonio A F Carioca, Kristine R Penner, Jill Alldredge, Teresa Longoria, Robert A Nagourney. Platinum resistance in gynecologic malignancies: Response, disease free and overall survival are predicted by biochemical signature: A metabolomic analysis.
Gynecologic oncology.
2021 10; 163(1):162-170. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2021 10; 27(19):5213-5224. doi:
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Cancer research and treatment.
2021 Oct; 53(4):1166-1173. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2021 09; 27(18):4983-4993. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2021 Sep; 75(?):105179. doi:
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In vivo (Athens, Greece).
2021 Sep; 35(5):2821-2829. doi:
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Advances in chronic kidney disease.
2021 09; 28(5):402-414.e1. doi:
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BMC urology.
2021 Aug; 21(1):114. doi:
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Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences.
2021 Aug; 53(4):686-691. doi:
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Zhonghua fu chan ke za zhi.
2021 Jun; 56(6):393-400. doi:
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Clinical cancer research : an official journal of the American Association for Cancer Research.
2021 06; 27(11):3028-3038. doi:
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Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
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Internal medicine (Tokyo, Japan).
2021 May; 60(10):1577-1581. doi:
10.2169/internalmedicine.5629-20. [PMID: 33328400] - Masataka Iwano, Kohei Sadahiro, Takuya Maruo, Shinpei Kawarai, Hideki Kayanuma, Kensuke Orito. Serum concentration and safety of intravenous drip versus subcutaneous administration of carboplatin in dogs.
The Journal of veterinary medical science.
2021 May; 83(5):775-779. doi:
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Pediatric hematology and oncology.
2021 05; 38(4):403-405. doi:
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International journal of molecular sciences.
2021 Apr; 22(9):. doi:
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Journal of investigational allergology & clinical immunology.
2021 Apr; 31(2):178-179. doi:
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Cancer medicine.
2021 04; 10(7):2250-2258. doi:
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Journal of thrombosis and thrombolysis.
2021 Apr; 51(3):577-583. doi:
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Biomaterials.
2021 04; 271(?):120758. doi:
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Thrombosis research.
2021 04; 200(?):91-98. doi:
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The Lancet. Oncology.
2021 04; 22(4):439-449. doi:
10.1016/s1470-2045(21)00006-1. [PMID: 33705695] - May Myat Mon, Chantragan Srisomsap, Daranee Chokchaichamnankit, Kamolwan Watcharatanyatip, Churat Weeraphan, Jisnuson Svasti, Kajornkiat Maneechai, Paramee Thongsuksai, Pritsana Raungrut. Serum Proteomic Profiling Reveals Differentially Expressed IGHG3 and A1AG1 as Potential Predictors of Chemotherapeutic Response in Advanced Non-small Cell Lung Cancer.
Anticancer research.
2021 Apr; 41(4):1871-1882. doi:
10.21873/anticanres.14953. [PMID: 33813392] - Kathryn Taikowski, Adam J Rudinsky, Darian S Louke, Emma Warry, Joelle M Fenger. Plasma Cytokeratin 18 and fecal Alpha-1 Antitrypsin concentrations in dogs with osteosarcoma receiving carboplatin chemotherapy.
Veterinary medicine and science.
2021 03; 7(2):385-392. doi:
10.1002/vms3.392. [PMID: 33222415] - Corey Tsang, Ayub Akbari, Dominque Frechette, Pierre Antoine Brown. Accurate determination of glomerular filtration rate in adults for carboplatin dosing: Moving beyond Cockcroft and Gault.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Mar; 27(2):368-375. doi:
10.1177/1078155220978446. [PMID: 33297846] - Kenji Zennami, Makoto Sumitomo, Kiyoshi Takahara, Takuhisa Nukaya, Masashi Takenaka, Kosuke Fukaya, Manabu Ichino, Naohiko Fukami, Hitomi Sasaki, Mamoru Kusaka, Ryoichi Shiroki. Two cycles of neoadjuvant chemotherapy improves survival in patients with high-risk upper tract urothelial carcinoma.
BJU international.
2021 03; 127(3):332-339. doi:
10.1111/bju.15230. [PMID: 32896105] - Ye-Hua Shen, Shou-Yin Jiang. Primary yolk sac tumor of pterygopalatine fossa with loss of vision: A case report.
Medicine.
2021 Feb; 100(8):e24916. doi:
10.1097/md.0000000000024916. [PMID: 33663127] - Wei Wang, Ming Liu, Boyong Ding. Comparison of the short-term efficacy and serum markers between lobaplatin/paclitaxel- And carboplatin/paclitaxel-based adjuvant chemotherapy in patient with ovarian cancer.
Journal of clinical pharmacy and therapeutics.
2021 Feb; 46(1):166-172. doi:
10.1111/jcpt.13276. [PMID: 33098169] - Yi Hu, Chun Yang, Tania Amorim, Mohsin Maqbool, Jenny Lin, Chen Li, Chuanfeng Fang, Li Xue, Ariel Kwart, Hua Fang, Mei Yin, Allison J Janocha, Daisuke Tsuchimoto, Yusaku Nakabeppu, Xiaofeng Jiang, Alex Mejia-Garcia, Faiz Anwer, Jack Khouri, Xin Qi, Qing Y Zheng, Jennifer S Yu, Shan Yan, Thomas LaFramboise, Kenneth C Anderson, Leal C Herlitz, Nikhil C Munshi, Jianhong Lin, Jianjun Zhao. Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury.
Cancer research.
2021 02; 81(3):713-723. doi:
10.1158/0008-5472.can-20-1010. [PMID: 33288657] - Duygu Alpaslan, Tuba Erşen Dudu, Nahit Aktaş. Synthesis and characterization of novel organo-hydrogel based agar, glycerol and peppermint oil as a natural drug carrier/release material.
Materials science & engineering. C, Materials for biological applications.
2021 Jan; 118(?):111534. doi:
10.1016/j.msec.2020.111534. [PMID: 33255087] - Rui Yang, You-Yang Shi, Xiang-Hui Han, Sheng Liu. The Impact of Platinum-Containing Chemotherapies in Advanced Triple-Negative Breast Cancer: Meta-Analytical Approach to Evaluating Its Efficacy and Safety.
Oncology research and treatment.
2021; 44(6):333-343. doi:
10.1159/000515353. [PMID: 33975311] - Youngjoo Lee, Jungnam Joo, You Jin Lee, Eun Kyung Lee, Sohyun Park, Tae-Sung Kim, Soo-Hyun Lee, So Young Kim, Gyung-Ah Wie, Minjoung Park, Mi-Jung Kim, Jin Soo Lee, Ji-Youn Han. Randomized phase II study of platinum-based chemotherapy plus controlled diet with or without metformin in patients with advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands).
2021 01; 151(?):8-15. doi:
10.1016/j.lungcan.2020.11.011. [PMID: 33278671] - Theresa Vilsmaier, Helene Hildegard Heidegger, Lennard Schröder, Elisabeth Trapp, Alaleh Zati Zehni, Brigitte Rack, Wolfgang Janni, Sven Mahner, Tobias Weissenbacher, Udo Jeschke, Jan-Niclas Mumm. Interleukin 15 and Eotaxin correlate with the outcome of breast cancer patients vice versa independent of CTC status.
Archives of gynecology and obstetrics.
2021 01; 303(1):217-230. doi:
10.1007/s00404-020-05793-y. [PMID: 32929618] - Shivani Tendulkar, Suneel Dodamani. Chemoresistance in Ovarian Cancer: Prospects for New Drugs.
Anti-cancer agents in medicinal chemistry.
2021; 21(6):668-678. doi:
10.2174/1871520620666200908104835. [PMID: 32900355] - Mads Kingo Guldberg Hansen, Maja Patricia Smerdel, Marianne Waldstrøm, Rikke Fredslund Andersen, Parvin Adimi, Anders Jakobsen, Karina Dahl Steffensen. Carboplatin re-treatment in platinum-resistant epithelial ovarian cancer patients.
Cancer chemotherapy and pharmacology.
2020 12; 86(6):751-759. doi:
10.1007/s00280-020-04162-5. [PMID: 33067703] - Victor Passos Gibson, Rabeb Mouna Derbali, Huu Trong Phan, Houda Tahiri, Christine Allen, Pierre Hardy, Jeanne Leblond Chain. Survivin silencing improved the cytotoxicity of carboplatin and melphalan in Y79 and primary retinoblastoma cells.
International journal of pharmaceutics.
2020 Nov; 589(?):119824. doi:
10.1016/j.ijpharm.2020.119824. [PMID: 32861768] - Jelena S Katanic Stankovic, Dragica Selakovic, Vladimir Mihailovic, Gvozden Rosic. Antioxidant Supplementation in the Treatment of Neurotoxicity Induced by Platinum-Based Chemotherapeutics-A Review.
International journal of molecular sciences.
2020 Oct; 21(20):. doi:
10.3390/ijms21207753. [PMID: 33092125] - Luiz Carlos da Costa Junior, Clarissa Lourenço de Castro, Daniely Regina Freitas-Alves, Rosane Vianna-Jorge, Paulo Caleb Júnior Lima Santos. ABCB1 and ERCC1 gene polymorphisms are associated with nephro- and hepatotoxicity to carboplatin/paclitaxel-based chemotherapy in patients with gynecologic cancers.
European journal of clinical pharmacology.
2020 Oct; 76(10):1401-1408. doi:
10.1007/s00228-020-02934-9. [PMID: 32564116] - Anand Joshi, Jianxia Guo, Julianne L Holleran, Brian Kiesel, Sarah Taylor, Susan Christner, Robert A Parise, Brian M Miller, S Percy Ivy, Edward Chu, Raman Venkataramanan, Jan H Beumer. Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker.
Cancer chemotherapy and pharmacology.
2020 10; 86(4):535-545. doi:
10.1007/s00280-020-04145-6. [PMID: 32948918] - K Esther Broekman, Marieke A J Hof, Daan J Touw, Jourik A Gietema, Hans W Nijman, Joop D Lefrandt, An K L Reyners, Mathilde Jalving. Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer.
Investigational new drugs.
2020 10; 38(5):1454-1462. doi:
10.1007/s10637-020-00920-7. [PMID: 32146550] - Valentina Ranzuglia, Ilaria Lorenzon, Ilenia Pellarin, Maura Sonego, Alessandra Dall'Acqua, Sara D'Andrea, Sara Lovisa, Ilenia Segatto, Michela Coan, Jerry Polesel, Diego Serraino, Patrizia Sabatelli, Paola Spessotto, Barbara Belletti, Gustavo Baldassarre, Monica Schiappacassi. Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells.
Oncogene.
2020 10; 39(40):6370-6386. doi:
10.1038/s41388-020-01433-6. [PMID: 32848212] - Sarah Schoch, Sabine Gajewski, Jana Rothfuß, Andrea Hartwig, Beate Köberle. Comparative Study of the Mode of Action of Clinically Approved Platinum-Based Chemotherapeutics.
International journal of molecular sciences.
2020 Sep; 21(18):. doi:
10.3390/ijms21186928. [PMID: 32967255] - Andrey Soares, Fabio A Schutz, Diogo Assed Bastos, Denis Jardim, Fernando Sabino Marques Montiero. Use of Immunotherapy in Patients With Cancer During the COVID-19 Pandemic.
Oncology (Williston Park, N.Y.).
2020 09; 34(9):370-376. doi:
10.46883/onc.2020.3409.0370. [PMID: 32965669] - Huihan Ma, Qian Qin, Jiaqing Mi, Qinmei Feng. 1-MT inhibits the invasion of CBP-resistant ovarian cancer cells via down-regulating IDO expression and re-activating immune cells function.
BMC pharmacology & toxicology.
2020 09; 21(1):67. doi:
10.1186/s40360-020-00439-w. [PMID: 32912307] - A Laura Nijstad, Natasha K A van Eijkelenburg, Kathelijne C J M Kraal, Marieke J M Meijs, Clara T M M de Kanter, Marc R Lilien, Alwin D R Huitema. Cisplatin and carboplatin pharmacokinetics in a pediatric patient with hepatoblastoma receiving peritoneal dialysis.
Cancer chemotherapy and pharmacology.
2020 09; 86(3):445-449. doi:
10.1007/s00280-020-04130-z. [PMID: 32816154] - Corine de Jong, Vera H M Deneer, Johannes C Kelder, Henk Ruven, Toine C G Egberts, Gerarda J M Herder. Association between serum biomarkers CEA and LDH and response in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Thoracic cancer.
2020 07; 11(7):1790-1800. doi:
10.1111/1759-7714.13449. [PMID: 32383328] - Iman Al Dybiat, Alibi Baitukha, Cynthia Pimpie, Rachid Kaci, Marc Pocard, Farzaneh Arefi Khonsari, Massoud Mirshahi. Multi-nanolayer drug delivery using radiofrequency plasma technology.
BMC cancer.
2020 Jun; 20(1):565. doi:
10.1186/s12885-020-06989-w. [PMID: 32552705] - Luke McLean, James R Whittle, Jonathan Graham, Huda Ismail, Meir Lichtenstein, Rodney J Hicks, Orla McNally, Alan Herschtal, Mark Rosenthal, Danny Rischin, Anne Hamilton. Carboplatin dosing in the era of IDMS-creatinine; the Cockroft-Gault formula no longer provides a sufficiently accurate estimate of glomerular filtration rate for routine use in clinical care.
Gynecologic oncology.
2020 06; 157(3):793-798. doi:
10.1016/j.ygyno.2020.03.017. [PMID: 32220419] - Ruo-Xi Wang, Peng Ji, Yue Gong, Zhi-Ming Shao, Sheng Chen. Value of CXCL8-CXCR1/2 axis in neoadjuvant chemotherapy for triple-negative breast cancer patients: a retrospective pilot study.
Breast cancer research and treatment.
2020 Jun; 181(3):561-570. doi:
10.1007/s10549-020-05660-z. [PMID: 32361849] - Samineh Dehghanpour, Hamid Reza Pourzamani, Mohammad Mehdi Amin, Karim Ebrahimpour. Evaluation of toxic effects of platinum-based antineoplastic drugs (cisplatin, carboplatin and oxaliplatin) on green alga Chlorella vulgaris.
Aquatic toxicology (Amsterdam, Netherlands).
2020 Jun; 223(?):105495. doi:
10.1016/j.aquatox.2020.105495. [PMID: 32371336] - Akimasa Asai, Takayuki Katsuno, Makoto Yamaguchi, Shiho Iwagaitsu, Hironobu Nobata, Hiroshi Kinashi, Hiroshi Kitamura, Shogo Banno, Yasuhiko Ito. Carboplatin-related acute interstitial nephritis in a patient with pancreatic neuroendocrine tumor.
CEN case reports.
2020 05; 9(2):114-121. doi:
10.1007/s13730-019-00437-w. [PMID: 31834568] - Yuji Shibata, Nobuaki Kobayashi, Takashi Sato, Kentaro Nakashima, Takeshi Kaneko. The clinical significance of CXCL16 in the treatment of advanced non-small cell lung cancer.
Thoracic cancer.
2020 05; 11(5):1258-1264. doi:
10.1111/1759-7714.13387. [PMID: 32163231] - Daiki Mori, Hiroo Ishida, Tadahaya Mizuno, Sojiro Kusumoto, Yusuke Kondo, Saki Izumi, Genki Nakata, Yoshitane Nozaki, Kazuya Maeda, Yasutsuna Sasaki, Ken-Ichi Fujita, Hiroyuki Kusuhara. Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel.
Drug metabolism and disposition: the biological fate of chemicals.
2020 05; 48(5):387-394. doi:
10.1124/dmd.119.089474. [PMID: 32114508] - K Suzuki, Y Sato, R Nakahara, R Tatsuta, R Tanaka, H Itoh. Venous thromboembolisms and rheology in ovarian cancer patients after postoperative adjuvant paclitaxel and carboplatin therapy.
Die Pharmazie.
2020 05; 75(5):205-207. doi:
10.1691/ph.2020.9908. [PMID: 32393430] - Elizabeth A Maxwell, Heidi Phillips, Stuart C Clark-Price, Miranda D Vieson, Laura E Selmic, David J Schaeffer, Timothy M Fan. Pharmacokinetics of platinum and safety evaluation of carboplatin-impregnated calcium sulfate hemihydrate beads after implantation in healthy cats.
Veterinary surgery : VS.
2020 May; 49(4):748-757. doi:
10.1111/vsu.13372. [PMID: 31944331] - Ping Cheng, Huan Liu, Yinchuan Li, Peiling Pi, Yu Jiang, Shaozhen Zang, Xiaorong Li, Ailing Fu, Xiaoyuan Ren, Jianqiang Xu, Arne Holmgren, Jun Lu. Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Biochemical pharmacology.
2020 05; 175(?):113873. doi:
10.1016/j.bcp.2020.113873. [PMID: 32092292] - Abir Mukherjee, Chun-Yi Chiang, Helen A Daifotis, Kristin M Nieman, Johannes F Fahrmann, Ricardo R Lastra, Iris L Romero, Oliver Fiehn, Ernst Lengyel. Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance.
Cancer research.
2020 04; 80(8):1748-1761. doi:
10.1158/0008-5472.can-19-1999. [PMID: 32054768] - Eve Roberts, Jasper A W Mogg, Mark Barnfield, Gareth J Veal. Investigating current practices in renal function measurement and carboplatin dosing in children with cancer - a UK perspective.
Pediatric hematology and oncology.
2020 Apr; 37(3):235-244. doi:
10.1080/08880018.2020.1713939. [PMID: 31941404] - Angeles Alvarez Secord, Kirsten Bell Burdett, Kouros Owzar, David Tritchler, Alexander B Sibley, Yingmiao Liu, Mark D Starr, J Chris Brady, Heather A Lankes, Herbert I Hurwitz, Robert S Mannel, Krishnansu S Tewari, David M O'Malley, Heidi Gray, Jamie N Bakkum-Gamez, Keiichi Fujiwara, Matthew Boente, Wei Deng, Robert A Burger, Michael J Birrer, Andrew B Nixon. Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020 03; 26(6):1288-1296. doi:
10.1158/1078-0432.ccr-19-0226. [PMID: 31919136] - Hailing Xu, Dongqing Lv, Yinnan Meng, Miao Wang, Wei Wang, Chao Zhou, Suna Zhou, Xiaofeng Chen, Haihua Yang. Endostar improved efficacy of concurrent chemoradiotherapy with vinorelbine plus carboplatin in locally advanced lung squamous cell carcinoma patients with high serum Lp(a) concentration.
Annals of palliative medicine.
2020 Mar; 9(2):298-307. doi:
10.21037/apm.2020.01.16. [PMID: 32075401] - Melanie White-Koning, Marie Noëlle Paludetto, Félicien Le Louedec, Laurence Gladieff, Christine Chevreau, Etienne Chatelut, Florent Puisset. Formulae recently proposed to estimate renal glomerular filtration rate improve the prediction of carboplatin clearance.
Cancer chemotherapy and pharmacology.
2020 03; 85(3):585-592. doi:
10.1007/s00280-019-04020-z. [PMID: 31915969] - Tomohiro Enokida, Takenori Ogawa, Akihiro Homma, Kenji Okami, Shujiro Minami, Ayako Nakanome, Yasushi Shimizu, Daisuke Maki, Yuri Ueda, Takao Fujisawa, Atsushi Motegi, Akira Ohkoshi, Jun Taguchi, Koji Ebisumoto, Shogo Nomura, Susumu Okano, Makoto Tahara. A multicenter phase II trial of paclitaxel, carboplatin, and cetuximab followed by chemoradiotherapy in patients with unresectable locally advanced squamous cell carcinoma of the head and neck.
Cancer medicine.
2020 03; 9(5):1671-1682. doi:
10.1002/cam4.2852. [PMID: 31943834] - Kuifeng Xu, Junqi Liu, Chaojun Zhang. Intra-arterial chemotherapy combined with VEC intravenous chemotherapy in the treatment of advanced retinoblastoma.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2020 Mar; 25(2):1199-1205. doi:
NULL. [PMID: 32521926] - Yasser Elborai, Mohammad Almutereen, Ossama M Maher, Hanafy Hafez, Michelle A Lee, Leslie Lehmann. Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation.
Journal of the Egyptian National Cancer Institute.
2020 Feb; 32(1):9. doi:
10.1186/s43046-020-00024-6. [PMID: 32372349] - Vassiliki A Papadimitrakopoulou, Ji-Youn Han, Myung-Ju Ahn, Suresh S Ramalingam, Angelo Delmonte, Te-Chun Hsia, Janessa Laskin, Sang-We Kim, Yong He, Chun-Ming Tsai, Toyoaki Hida, Makoto Maemondo, Terufumi Kato, Suzanne Jenkins, Sabina Patel, Xiangning Huang, Gianluca Laus, Aleksandra Markovets, Kenneth S Thress, Yi-Long Wu, Tony Mok. Epidermal growth factor receptor mutation analysis in tissue and plasma from the AURA3 trial: Osimertinib versus platinum-pemetrexed for T790M mutation-positive advanced non-small cell lung cancer.
Cancer.
2020 01; 126(2):373-380. doi:
10.1002/cncr.32503. [PMID: 31769875] - Junliang Li, Jianxia Ma, Xuxia Zhang, Xiaohui Tai, Le Liu, Lingfang Zhang. Long Non-Coding RNA (lncRNA) BMP/OP-Responsive Gene (BORG) Promotes Development of Chemoresistance of Colorectal Cancer Cells to Carboplatin.
Medical science monitor : international medical journal of experimental and clinical research.
2020 Jan; 26(?):e919103. doi:
10.12659/msm.919103. [PMID: 31937750] - Raffaele Longo, Camille Jaud, William Gehin, Laurent Hennequin, Claire Bastien, Marco Campitiello, Antonio Rozzi, Francesca Plastino. Renal Metastases from a Nasal Cavity Mixed Squamous Cell and Adenoid Cystic Carcinoma: A Case Report.
The American journal of case reports.
2020 Jan; 21(?):e919781. doi:
10.12659/ajcr.919781. [PMID: 31911575] - Junjian Wang. Combination Treatment of Cervical Cancer Using Folate-Decorated, pH-Sensitive, Carboplatin and Paclitaxel Co-Loaded Lipid-Polymer Hybrid Nanoparticles.
Drug design, development and therapy.
2020; 14(?):823-832. doi:
10.2147/dddt.s235098. [PMID: 32161442]