Exact Mass: 368.1816
Exact Mass Matches: 368.1816
Found 500 metabolites which its exact mass value is equals to given mass value 368.1816
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Mitraphylline
Mitraphylline is a member of indolizines. Mitraphylline is a natural product found in Uncaria tomentosa, Mitragyna parvifolia, and other organisms with data available. See also: Cats Claw (part of); Mitragyna speciosa leaf (part of). Annotation level-1 Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1]. Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].
Uncarine
Uncarine E is a member of indolizines. Isopteropodine is a natural product found in Uncaria lanosa, Uncaria tomentosa, and other organisms with data available. See also: Cats Claw (part of). Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1]. Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1]. Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors[1].
UNCARIN C
Uncarine C is a member of indolizines. Uncarine c is a natural product found in Uncaria lanosa, Uncaria tomentosa, and other organisms with data available. See also: Cats Claw (part of).
Dehydroepiandrosterone sulfate
Dehydroepiandrosterone sulfate or DHEA-S is the sulfated form of dehydroepiandrosterone (DHEA). This sulfation is reversibly catalyzed by sulfotransferase 2A1 (SULT2A1) primarily in the adrenals, the liver, and small intestine. In the blood, most DHEA is found as DHEA-S with levels that are about 300 times higher than those of free DHEA. Orally-ingested DHEA is converted into its sulfate when passing through the intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, DHEAS levels show no diurnal variation. From a practical point of view, measurement of DHEA-S is preferable to DHEA since levels are more stable. DHEA (from which DHEA-S comes from) is a natural steroid prohormone produced from cholesterol by the adrenal glands, the gonads, adipose tissue, brain, and in the skin (by an autocrine mechanism). DHEA is the precursor of androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. Serum dehydroepiandrosterone sulfate is a classic marker for adrenarche, and subsequently for the individual hormonal milieu (PMID: 10599744). Dehydroepiandrosterone sulfate is an endogenously produced sex steroid that has been hypothesized to have anti-aging effects (PMID: 16960027). It also has been inversely associated with the development of atherosclerosis (PMID: 8956025). DHEAS or Dehydroepiandrosterone sulfate is the sulfated form of DHEA. This sulfation is reversibly catalyzed by sulfotransferase (SULT2A1) primarily in the adrenals, the liver, and small intestine. In the blood, most DHEA is found as DHEAS with levels that are about 300 times higher than those of free DHEA. Orally-ingested DHEA is converted to its sulfate when passing through intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, DHEAS levels show no diurnal variation. From a practical point of view, measurement of DHEAS is preferable to DHEA, as levels are more stable. DHEA (from which DHEAS comes from) is a natural steroid prohormone produced from cholesterol by the adrenal glands, the gonads, adipose tissue, brain and in the skin (by an autocrine mechanism). DHEA is the precursor of androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. DHEAS can serve as a precursor for testosterone; androstenedione; estradiol; and estrone. [HMDB] D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
uncarine d
Testosterone sulfate
Testosterone is a predominantly male hormone, though females do produce certain amounts of it. The primary female hormone is estrogen and males also produce certain amounts of this hormone. testosterone causes the appearance of male traits (i.e deepening voice, pubic and facial hairs, muscular build, etc.). The keto group on C-17 is reduced to an alcohol to yield testosterone. Testosterone is a steroid hormone from the androgen group. testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. On average, the adult male body produces about twenty times the amount of testosterone that an adult females body does. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5-alpha -dihydrotestosterone (DHT) by the cytoplasmic enzyme 5-alpha-reductase(5-alpha-reduktas). DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects. It is important to note that if there is a too low amount of 5-alpha-reductase(5-alfa-reduktas), the body (of a human) will continue growing into a female with testicles. Testerone is a predominantly male hormone, though females do produce certain amounts of it. The primary female hormone is estrogen and males also produce certain amounts of this hormone. testosterone causes the appearance of male traits (i.e deepening voice, pubic and facial hairs, muscular build, etc.) D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside]
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is found in root vegetables. (2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is a constituent of the roots of cassava (Manihot esculenta). Constituent of the roots of cassava (Manihot esculenta). (2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] is found in root vegetables.
Epitestosterone sulfate
Epitestosterone Sulfate is a sulfate conjugate of endogenous steroids hormone epitestosterone produced by both sexes and was determined using LC-MS/MS. A human metabolite taken as a putative food compound of mammalian origin [HMDB]
LysoPA(a-13:0/0:0)
LysoPA(a-13:0/0:0) is a lysophosphatidic acid. It is a glycerophospholipid in which a phosphate moiety occupies a glycerol substitution site. Lysophosphatidic acids can have different combinations of fatty acids of varying lengths and saturation attached at the C-1 (sn-1) or C-2 (sn-2) position. Fatty acids containing 16 and 18 carbons are the most common. LysoPA(a-13:0/0:0), in particular, consists of one chain of anteisotridecanoic acid at the C-1 position. Lysophosphatidic acid is the simplest possible glycerophospholipid. It is the biosynthetic precursor of phosphatidic acid. Although it is present at very low levels only in animal tissues, it is extremely important biologically, influencing many biochemical processes.
LysoPA(i-13:0/0:0)
LysoPA(i-13:0/0:0) is a lysophosphatidic acid. It is a glycerophospholipid in which a phosphate moiety occupies a glycerol substitution site. Lysophosphatidic acids can have different combinations of fatty acids of varying lengths and saturation attached at the C-1 (sn-1) or C-2 (sn-2) position. Fatty acids containing 16 and 18 carbons are the most common. LysoPA(i-13:0/0:0), in particular, consists of one chain of isotridecanoic acid at the C-1 position. Lysophosphatidic acid is the simplest possible glycerophospholipid. It is the biosynthetic precursor of phosphatidic acid. Although it is present at very low levels only in animal tissues, it is extremely important biologically, influencing many biochemical processes.
1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D063385 - Cannabinoid Receptor Modulators D018377 - Neurotransmitter Agents > D063385 - Cannabinoid Receptor Modulators > D063386 - Cannabinoid Receptor Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol
[(2R,5S,15S)-2,15-Dimethyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl]oxidanesulfonic acid
Dialdehyde
Cyclohexanol, 4-(4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl)-, trans-
Fabatin
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents Constituent of Vicia faba. Fabatin is found in broad bean. D049990 - Membrane Transport Modulators
N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide
(2S,3S,4S,8R,9S,13R,14R,15S,16R)-3,4,8,14,15-pentahydroxy-2,13,16-trimethyl-6-methylidene-10-oxatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadecan-11-one
phthalic acid mono-[2-methyl-5-(2-methyl-3-methylene-[2]norbornyl)-pent-2-enyl ester]|Phthalsaeure-mono-[2-methyl-5-(2-methyl-3-methylen-[2]norbornyl)-pent-2-enylester]
11-ethyl-5,6-dioxo-5,6,8,9,10,11,12,14-octahydro-4bH-7,14-diaza-7,11-methano-cycloundeca[a]indene-13-carboxylic acid methyl ester|Ervinidin
1-formyl-19-hydroxy-17-methoxy-aspidospermidin-21-oic acid lactone|1-Formyl-19-hydroxy-17-methoxy-aspidospermidin-21-saeure-lacton|Dichotamin|dichotamine
9-ethylidene-12-hydroxy-6,7,7a,8,8a,9,10,12-octahydro-5H-indolo[3,2,1-ij]pyrano[3,4-b][1,5]naphthyridine-12a-carboxylic acid methyl ester|Talbotin|Talbotine,
2-(4-Methoxyphenyl)-5,7-dimethoxy-6-(3-methyl-2-butenyl)-3,4-dihydro-2H-1-benzopyran
5-oxo-17-deacetyl-1,2-dihydroakuammiline|methyl (16R,19E)-1,2-dihydro-16-(hydroxymethyl)-5-oxo-akuammilan-17-oate
2-methylpropanyl 6-O-beta-D-apiofuranosyl-beta-D-glucopyranoside
8-hydroxy-10-oxo-aspidofractinine-3-carboxylic acid methyl ester|Kopsinilamin
3alpha-isobutyryloxy-5beta-(4-hydroxytigloyloxy)-7-hydroxycarvotacetone|3alpha-isobutyryloxy-5beta-<4-hydroxytigloyloxy>-7-hydroxycarvotacetone
8-hydroxy-19-oxo-ibogamine-18-carboxylic acid methyl ester|Eglandulosin
tert-Butyl glycoside-alpha-Pyranose-2-O-beta-D-Glucopyranosyl-L-arabinose
(2S,5S)-2,5-bis<(3R)-3-methyl-2,5-dioxo-piperazin-1-yl>cyclohexane-1,4-diol|(2S,5S)-2,5-bis[(3R)-3-methyl-2,5-dioxo-piperazin-1-yl]cyclohexane-1,4-diol
(6E)-1-(2,4-dihydroxyphenyl)-3,7-dimethyl-3-vinyl-8-(4-methyl-2-furyl)-6-octen-1-one|1-(2,4-dihydroxyphenyl)-3,7-dimethyl-3-vinyl-8-(4-methyl-2-furyl)-6(E)-octen-1-one
Na-formylechitamide|Na-Formylechitamidine|Na-ylechitamidine
(19S)-17,19-epoxy-10-hydroxy-coryn-16-ene-16-carboxylic acid methyl ester|10-hydroxy-19alpha-methyl-18-oxa-yohimb-16-ene-16-carboxylic acid methyl ester|10-Hydroxy-Ajmalicin|10-hydroxy-ajmalicine|10-hydroxyajmalicine|Hydroxy-10-ajmalicin|O-demethyl-cabucine
2,5alpha-epoxy-12-methoxy-(2alpha)-1,2-dihydro-akuammilan-17-oic acid methyl ester|Vincaricin|vincaricine
4,11-dihydroxy-6,7-didehydro-11,20-cyclo-aspidospermidine-3-carboxylic acid methyl ester|Melobalin
9-demethoxy-18-demethylgardneramine
A natural product found in Gardneria ovata.
1beta,3alpha-diethyloxy-7-hydroxymethyl-4-(3-methyl-butyryloxymethyl)-cyclopenta-4(4a),7(7a)-diene[c]pyran-6-one
10-hydroxyakuammidine|methyl (19E)-10,17-dihydroxysarpagan-16-carboxylate
(4E,7E)-1-(2,4-dihydroxyphenyl)-9-(4-methylfuran-2-yl)-3,4,8-trimethylnona-4,7-dien-1-one|ferulaeone D
(4S,4aS,5R,6S,8aS,9aS)-6-(acetyloxy)-4a,5,6,7,8,8a,9,9a-octahydro-8a-hydroxy-4,9a-dimethoxy-3,4a,5-trimethylnaphtho[2,3-b]furan-2(4H)-one|3beta-acetoxy-10beta-hydroxy-6beta,8beta-dimethoxyeremophil-7(11)-en-12,8alpha-olide
ent-6xi,7xi-epoxy-3xi-hydroxy-3xi-methoxymethyl-1,2-didehydro-aspidospermidin-8-one
1-acetyl-17,19-epoxy-11-methoxy-18-nor-cur-19-en-17-ol|11-Methoxy-diabolin
11-methoxy-19,20alpha-epoxyakuammicine|19,20alpha-epoxy-11-methoxyakuammicine
1-hydroxy-6,6,9-trimethyl-3-pentyl-6H-benzo[c]chromene-2-carboxylic acid methyl ester|Cannabinolinsaeure-methylester|Cannabinolsaeure-methylester
Pentanoic acid, 4,5-bis(benzoylamino)-, ethyl ester
17-phenyl trinor Prostaglandin A2
Isomitraphyllin
Isomitraphylline is a natural product found in Uncaria tomentosa, Mitragyna parvifolia, and other organisms with data available. See also: Cats Claw (part of).
16-Epivoacarpine
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans[1].
C21H24N2O4_2,6-Methano-1H-azecino[5,4-b]indole-14-carboxylic acid, 5-ethylidene-2,3,4,5,6,7,8,9-octahydro-3-methyl-8-oxo-, methyl ester, 3-oxide, (5E)
Dehydroepiandrosterone sulfate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.
C19H28O7_4H-Phenanthro[10,1-bc]furan-4-one, tetradecahydro-1,2,6,9,10-pentahydroxy-3,10a,10c-trimethyl-7-methylene-, (1S,2R,3R,5aS,6R,9S,10S,10aS,10cR)
C21H24N2O4_(1R,5R,8S,16S,17S)-11,12-Dimethoxy-5,15-diazahexacyclo[13.4.2.0~1,16~.0~5,16~.0~8,17~.0~9,14~]henicosa-2,9,11,13-tetraen-21-one 5-oxide
(S,E)-2-(4,8-dimethylnona-3,7-dien-1-yl)-5-hydroxy-2-methyl-2H-chromene-7,8-dicarbaldehyde
(2S,3S,4S,8R,9S,13R,14R,15S,16R)-3,4,8,14,15-pentahydroxy-2,13,16-trimethyl-6-methylidene-10-oxatetracyclo[7.6.1.0²,?.0¹²,¹?]hexadecan-11-one
Ala Ala Ala His
Ala Ala His Ala
Ala His Ala Ala
Gly Gly His Val
Gly Gly Val His
Gly His Gly Val
Gly His Val Gly
Gly Val Gly His
Gly Val His Gly
His Ala Ala Ala
His Gly Gly Val
His Gly Val Gly
His Val Gly Gly
Val Gly Gly His
Val Gly His Gly
Val His Gly Gly
Testosterone sulfate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens A steroid sulfate that is testosterone substituted by a sulfoxy group at position 17.
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside]
Vobasine N4-oxide
Longilactone, delta-4(18)-Isomer, 2alpha-alcoho
trans,trans-3,4,5-trifluorophenyl 4-ethylbicyclohexyl-4-carboxylate
tert-butyl 4-(cyanomethyl)-4-(4-Methylphenyl)piperidine-1-carbox
SB 239063
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
TERT-BUTYL(3-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOXY)DIMETHYLSILANE
BMS-690514
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor
tert-Butyl 5-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
4,4,4,4,7,7-hexamethyl-2,2-spirobi[3H-chromene]-6,6-diol
4,4-Dihydroxy-3,3,5,5-tetramethyldiphenylmethane diglycidyl ether
Thiourea, N-[2-(1H-benzimidazol-2-yl)ethyl]-N-(2-methoxyethyl)-N-(phenylmethyl)- (9CI)
2-Hydroxy-2-methyl-1-phenyl-1-propanone mixt. with (1-hydroxycyclohexyl)phenylmethanone
METHYL 2-(BENZYLOXY)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE
Arildone
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C254 - Anti-Infective Agent > C281 - Antiviral Agent
amphetamine sulfate
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
(2S)-((6-O-(beta-D-apiofuranosyl)beta-D-glucopyranosyl)oxy)butane
4-Amino-1-((4-(3-methoxyphenylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-3-ol
[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl](4,5,6,7-tetrahydro-2H-indazol-3-yl)methanone
Dextroamphetamine sulfate
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
3,4,8,14,15-Pentahydroxy-2,13,16-trimethyl-6-methylidene-10-oxatetracyclo[7.6.1.02,7.012,16]hexadecan-11-one
methyl (1R,10S,11S,12E,17S)-10-(dihydroxymethyl)-12-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraene-10-carboxylate
[(2R,10R,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl]oxidanesulfonic acid
methyl (2Z)-4-formyl-2-(hydroxymethylidene)-3-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-ylmethyl)hex-5-enoate
1-butyl-5-[1-[2-(1H-indol-3-yl)ethylamino]ethylidene]-1,3-diazinane-2,4,6-trione
(1R,5R,8S,16S,17S)-11,12-Dimethoxy-5-oxido-15-aza-5-azoniahexacyclo[13.4.2.01,16.05,16.08,17.09,14]henicosa-2,9,11,13-tetraen-21-one
4-[cyclohexyl(methyl)amino]-N-(6-methyl-2-pyridinyl)-3-nitrobenzamide
5-(4-Morpholinoanilino)-5-oxo-3-phenylpentanoic acid
3,4-dimethoxy-N-[4-[oxo(1-piperidinyl)methyl]phenyl]benzamide
3-[4-(4-Butan-2-ylphenyl)sulfonyl-1-piperazinyl]butanoic acid
(E)-3-(2,5-dimethoxyphenyl)-N-methyl-N-[2-(4-methylanilino)-2-oxoethyl]prop-2-enamide
4-[(E)-{2-[2,6-di(pyrrolidin-1-yl)pyrimidin-4-yl]hydrazinylidene}methyl]benzene-1,2-diol
methyl (1R,9S,11S,14E,15S,17S)-14-ethylidene-19-(hydroxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
Hoerhammericine
An Aspidosperma alkaloid with formula C21H24N2O4 found in Catharantheus lanceus. Note that the stereoconfiguration of the epoxy group is based on CHEBI:144374, and of the 19 hydroxy group on CHEBI:144372 (the same enzyme produces the two).
N-[[(2S,3R,4S)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
N-[[(2R,3S,4S)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
(2S)-2-[(4R,5R)-4-methyl-5-(methylaminomethyl)-1,1-dioxo-8-[(E)-prop-1-enyl]-4,5-dihydro-3H-6,1lambda6,2-benzoxathiazocin-2-yl]propan-1-ol
N-[[(2S,3S,4R)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2R,3S,4R)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3R,4R)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
N-[[(2S,3S,4S)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
(6R,7R,8S)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7S,8R)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7S,8S)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(2R)-2-[(4S,5S)-4-methyl-5-(methylaminomethyl)-1,1-dioxo-8-[(E)-prop-1-enyl]-4,5-dihydro-3H-6,1lambda6,2-benzoxathiazocin-2-yl]propan-1-ol
N-[[(2S,3R,4S)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3S,4S)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2R,3R,4S)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3R,4R)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2R,3S,4S)-1-benzoyl-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2R,3S,4R)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
N-[[(2R,3R,4R)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
N-[[(2R,3R,4S)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
N-[[(2S,3S,4R)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide
methyl (1R,9S,10S,11S)-10-(hydroxymethyl)-6-oxo-12-(2-phenylethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
methyl (1S,9R,10R,11R)-10-(hydroxymethyl)-6-oxo-12-(2-phenylethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
(6S,7R,8R)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7S,8S)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7R,8S)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7R,8R)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7S,8R)-7-[4-(2-cyclopropylethynyl)phenyl]-8-(hydroxymethyl)-4-(2-methoxy-1-oxoethyl)-1,4-diazabicyclo[4.2.0]octan-2-one
4-(4-Hydroxy-3,5-dimethoxyphenyl)-2,7,7-trimethyl-5-oxo-4,4a,6,8-tetrahydroquinoline-3-carbonitrile
methyl (1R,12S,13S,15R,20R)-12-[(1R)-1-hydroxyethyl]-14-oxa-8,17-diazahexacyclo[10.7.1.01,9.02,7.013,15.017,20]icosa-2,4,6,9-tetraene-10-carboxylate
(2S,3S,4S,8R,9S,13R,14R,15S,16R)-3,4,8,14,15-pentahydroxy-2,13,16-trimethyl-6-methylidene-10-oxatetracyclo[7.6.1.0(2),.0(1)(2),(1)]hexadecan-11-one
methyl (1S,12S,13S,14R,15E,17S)-15-ethylidene-7-methoxy-17-oxido-3-aza-17-azoniapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4(9),5,7-tetraene-13-carboxylate
CB13
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D063385 - Cannabinoid Receptor Modulators D018377 - Neurotransmitter Agents > D063385 - Cannabinoid Receptor Modulators > D063386 - Cannabinoid Receptor Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
MRK-016
MRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77?and 1.4?nM for human?GABAA?α1β3γ2, GABAA?α2β3γ2, GABAA?α3β3γ2, and GABAA?α5β3γ2, respectively; MRK-016 also readily penetrates the CNS.
(2r,3r)-3-chloro-3,7,11-trimethyl-1-(5-nitro-1h-pyrrol-3-yl)dodeca-6,10-dien-2-ol
methyl (12s,13s,15r,17s,19s)-13-acetyl-19-hydroxy-1,11-diazapentacyclo[13.3.1.0²,⁷.0⁸,¹⁸.0¹²,¹⁷]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
(1s,12s,13r,14s,15e,17s)-15-ethylidene-13-(hydroxymethyl)-13-(methoxycarbonyl)-3,17-diazapentacyclo[12.3.1.0²,¹⁰.0⁴,⁹.0¹²,¹⁷]octadeca-2(10),4,6,8-tetraen-17-ium-17-olate
1,12-dihydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.0⁴,⁸]tetradecan-9-yl 2-methylpropanoate
methyl (1's,3r,4'as,5'as,10'ar)-2-hydroxy-1'-methyl-1',4'a,5',5'a,7',8',10',10'a-octahydrospiro[indole-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
methyl (1r,12s,19r)-5-hydroxy-12-[(1r)-1-hydroxyethyl]-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2,4,6,9,13-pentaene-10-carboxylate
methyl (1r,9r,11s,14z,15r,19s)-14-ethylidene-6-methoxy-18-oxa-2,12-diazahexacyclo[9.6.1.1⁹,¹⁵.0¹,⁹.0³,⁸.0¹²,¹⁷]nonadeca-3,5,7-triene-19-carboxylate
(1r,4r,6s,8r,9s,10s,11s)-10-(acetyloxy)-6-formyl-9-isopropyl-1-methyl-5,12-dioxatricyclo[9.1.0.0⁴,⁶]dodecan-8-yl acetate
[(1r,3r)-1,3-diethoxy-7-(hydroxymethyl)-6-oxo-1h,3h,5h-cyclopenta[c]pyran-4-yl]methyl 3-methylbutanoate
1,13-dihydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.0⁴,⁸]tetradecan-9-yl 2-methylpropanoate
5-(6-bromo-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl)-3-methylpent-1-en-3-ol
methyl (1s,12r,15s,16r,18s)-16-ethyl-12-hydroxy-11-oxo-3,13-diazapentacyclo[13.3.1.0²,¹⁰.0⁴,⁹.0¹³,¹⁸]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
methyl (1'r,2r,3r,11'r,17's)-5'-methoxy-3-methyl-8',14'-diazaspiro[oxirane-2,12'-pentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadecane]-2',4',6',9'-tetraene-10'-carboxylate
methyl (1's,3s,5'as,10'as)-2-hydroxy-1'-methyl-1',4'a,5',5'a,7',8',10',10'a-octahydrospiro[indole-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
4-{[(1s,4r,6r,7r,8r,9r,13s)-6,9-dihydroxy-2,2,9-trimethyl-12-oxatetracyclo[6.3.2.0¹,⁴.0⁵,¹³]tridecan-7-yl]oxy}-4-oxobutanoic acid
(1's,2'r,3s,7'r,9's)-6'-acetyl-6-methoxy-1-methyl-4'-oxa-12'-azaspiro[indole-3,10'-tricyclo[7.2.1.0²,⁷]dodecan]-5'-en-2-one
methyl 2-hydroxy-4'-methyl-4',4'a,5',6',8',9',10'a,10'b-octahydrospiro[indole-3,10'-pyrano[3,4-g]indolizine]-1'-carboxylate
methyl 5-hydroxy-12-(1-hydroxyethyl)-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2,4,6,9,13-pentaene-10-carboxylate
methyl 5'-methoxy-3-methyl-8',14'-diazaspiro[oxirane-2,12'-pentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadecane]-2',4',6',9'-tetraene-10'-carboxylate
(1r,4s,4as,8s,11e,12as)-4-bromo-8-isopropyl-1,4a-dimethyl-7-methylidene-3,4,5,6,8,9,10,12a-octahydro-2h-benzo[10]annulen-1-ol
(3as,4s,6s,10r,11s,11ar)-4,10-dihydroxy-6,10-dimethyl-3-methylidene-2,5-dioxo-octahydrocyclodeca[b]furan-11-yl 2-methylpropanoate
methyl (1's,2r,4'as,5'ar,10'as)-1'-methyl-3-oxo-1',4'a,5',5'a,7',8',10',10'a-octahydro-1h-spiro[indole-2,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
4-{[(1s,4r,5r,6r,7r,8r,9r,13s)-6,9-dihydroxy-2,2,9-trimethyl-12-oxatetracyclo[6.3.2.0¹,⁴.0⁵,¹³]tridecan-7-yl]oxy}-4-oxobutanoic acid
methyl (1s,9r,16r,17r,18r,21r)-17,18-dihydroxy-2,12-diazahexacyclo[14.2.2.1⁹,¹².0¹,⁹.0³,⁸.0¹⁶,²¹]henicosa-3,5,7,14-tetraene-18-carboxylate
methyl (1r,9s,12s,13r,20s)-9-hydroxy-12-methyl-11-oxa-8,17-diazahexacyclo[11.6.1.1¹⁰,¹³.0¹,⁹.0²,⁷.0¹⁷,²⁰]henicosa-2,4,6,14-tetraene-10-carboxylate
methyl (1s,9r,16r,17s,18r,21r)-17,18-dihydroxy-2,12-diazahexacyclo[14.2.2.1⁹,¹².0¹,⁹.0³,⁸.0¹⁶,²¹]henicosa-3,5,7,14-tetraene-18-carboxylate
methyl (1'r,3s,4'as,5'as,10'as)-2-hydroxy-1'-methyl-1',4'a,5',5'a,7',8',10',10'a-octahydrospiro[indole-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate
methyl (1s,12s,15r,17s,18s)-17-ethyl-12-hydroxy-11-oxo-3,13-diazapentacyclo[13.3.1.0²,¹⁰.0⁴,⁹.0¹³,¹⁸]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
(2s)-2,5,7-trimethoxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-3,4-dihydro-1-benzopyran
methyl 18-hydroxy-20-oxo-5,15-diazahexacyclo[11.5.2.1¹,¹².0⁴,¹².0⁶,¹¹.0¹⁵,²¹]henicosa-6,8,10-triene-4-carboxylate
(2s)-2-hydroxy-2-{[(2e)-3-(methylsulfanyl)prop-2-enoyl]oxy}ethyl (2z,4e,11e)-trideca-2,4,11-trienoate
methyl (1r,9s,11s,14e,15s,17s,19r)-14-ethylidene-19-(hydroxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.1⁹,¹⁵.0¹,⁹.0³,⁸.0¹²,¹⁷]nonadeca-3,5,7-triene-19-carboxylate
11-Hydroxy-14,15alpha-epoxytabersonine
{"Ingredient_id": "HBIN000432","Ingredient_name": "11-Hydroxy-14,15alpha-epoxytabersonine","Alias": "11-hydroxy-14,15alpha-epoxytabersonine; 11-hydroxy-14,15\u03b1-epoxytabersonine","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CCC12CC(=C3C4(C1N(CC4)CC5C2O5)C6=C(N3)C=C(C=C6)O)C(=O)OC","Ingredient_weight": "368.47","OB_score": "13.47224587","CAS_id": "NA","SymMap_id": "SMIT00950","TCMID_id": "31188;10092","TCMSP_id": "MOL003246","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
16-epideacetylakuammilinen(4)-oxide
{"Ingredient_id": "HBIN001893","Ingredient_name": "16-epideacetylakuammilinen(4)-oxide","Alias": "NA","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CC=C1C[N+]2(CCC34C5=CC=CC=C5N=C3C2CC1C4(CO)C(=O)OC)[O-]","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6878","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
16-epi-voacarpine
{"Ingredient_id": "HBIN001897","Ingredient_name": "16-epi-voacarpine","Alias": "NA","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CC=C1CN2C3CC4=C(C2(CC1C3(CO)C(=O)OC)O)NC5=CC=CC=C45","Ingredient_weight": "368.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "7038","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "137706068","DrugBank_id": "NA"}
2α-hydroxytirotundin
{"Ingredient_id": "HBIN005297","Ingredient_name": "2\u03b1-hydroxytirotundin","Alias": "NA","Ingredient_formula": "C19H28O7","Ingredient_Smile": "CC1CC2C(C(CC3(CC(C1(O3)O)O)C)OC(=O)C(C)C)C(=C)C(=O)O2","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10768","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
7-isopteropodine
{"Ingredient_id": "HBIN013299","Ingredient_name": "7-isopteropodine","Alias": "NA","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "31370","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
akuammidine n-oxide
{"Ingredient_id": "HBIN015026","Ingredient_name": "akuammidine n-oxide","Alias": "akuammidinen-oxide","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CC=C1C[N+]2(C3CC1C(C2CC4=C3NC5=CC=CC=C45)(CO)C(=O)OC)[O-]","Ingredient_weight": "368.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "25819;825","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "102423744","DrugBank_id": "NA"}
akuammilinen(4)-oxide
{"Ingredient_id": "HBIN015029","Ingredient_name": "akuammilinen(4)-oxide","Alias": "NA","Ingredient_formula": "C21H24N2O4","Ingredient_Smile": "CC=C1C[N+]2(C3CC1C(C2CC4=C3NC5=CC=CC=C45)(CO)C(=O)OC)[O-]","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "827","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}