Exact Mass: 351.0412708
Exact Mass Matches: 351.0412708
Found 144 metabolites which its exact mass value is equals to given mass value 351.0412708,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of arthritis, primary dysmenorrhea, fever; and as an analgesic, especially where there is an inflammatory component. It is closely related to piroxicam. In Europe it is marketed under the brand names Movalis, Melox, and Recoxa. In North America it is generally marketed under the brand name Mobic. In Latin America, the drug is marketed as Tenaron. [Wikipedia] CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4454; ORIGINAL_PRECURSOR_SCAN_NO 4451 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4456; ORIGINAL_PRECURSOR_SCAN_NO 4454 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8780; ORIGINAL_PRECURSOR_SCAN_NO 8777 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4467; ORIGINAL_PRECURSOR_SCAN_NO 4465 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8736; ORIGINAL_PRECURSOR_SCAN_NO 8735 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8828; ORIGINAL_PRECURSOR_SCAN_NO 8823 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4500; ORIGINAL_PRECURSOR_SCAN_NO 4499 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4466; ORIGINAL_PRECURSOR_SCAN_NO 4465 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8798; ORIGINAL_PRECURSOR_SCAN_NO 8793 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8836; ORIGINAL_PRECURSOR_SCAN_NO 8834 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8839; ORIGINAL_PRECURSOR_SCAN_NO 8837 CONFIDENCE standard compound; INTERNAL_ID 487; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4468; ORIGINAL_PRECURSOR_SCAN_NO 4467 M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor CONFIDENCE standard compound; INTERNAL_ID 1152 D000893 - Anti-Inflammatory Agents
Tos-phe-CH2CL
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015842 - Serine Proteinase Inhibitors D009676 - Noxae > D000477 - Alkylating Agents > D000590 - Amino Acid Chloromethyl Ketones D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
N-(3-Chloro-2-oxo-1-(phenylmethyl)propyl)-4-methylbenzenesulfonamide
1-(2,4-Dichlorophenyl)-1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)ethanol
3-(((4,7-Dichloro-1,3-benzoxazol-2-yl)methyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
2-Methyl-N-(5-methyl-2-thiazolyl)-1,1,4-trioxo-3H-1$l^{6},2-benzothiazine-3-carboxamide
N-[(3-Chloro-2-hydroxy-5-nitrophenyl)carbamothioyl]benzamide
2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)propanedioic acid
C16H14ClNO4S (351.03320340000005)
N-[4-Chloro-3-(3-methylbut-2-enoxy)phenyl]-2-methylthiophene-3-carbothioamide
Lindechunine A
An isoquinoline alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2, methoxy groups at positions 3 and 11 and a hydroxy group at position 10. Isolated from the roots of Lindera chunii, it exhibits anti-HIV activity.
2-Bromo-4-oxo-8-amino-3,4,5,6-tetrahydro-3,5,7,9-tetraazabenzo[e]azulene-10-carboxylic acid methyl ester
C12H10BrN5O3 (350.99669700000004)
meloxicam
A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis. M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents
Chlorprothixene hydrochloride
C18H19Cl2NS (351.06151940000007)
Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].
2-(1,3-benzodioxol-5-yl)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazole
C18H13N3O3S (351.0677588000001)
2-chloro-9-(3-dimethylaminopropylidene)thioxanthene
C18H19Cl2NS (351.06151940000007)
(S)-2-Benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminothioacetate
benzyl 2,4-dichloro-5,6,8,9-tetrahydropyrimido[4,5-d]azepine-7-carboxylate
Adenosine, cyclic2,3-(hydrogen phosphate), monosodium salt (9CI)
C10H11N5NaO6P (351.03446360000004)
Tetraammineplatinum(II) chloride hydrate
Cl2H14N4OPt (351.01924640000004)
2-(P-TOLUIDINO)NAPHTHALENE-6-SULFONIC ACID POTASSIUM SALT
C17H14KNO3S (351.0331434000001)
Benzyl (4-chloro-3-cyano-7-quinolinyl)methylcarbamate
C19H14ClN3O2 (351.07744940000003)
S-2-BENZOTHIAZOLYL (Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO THIOACETATE
(1S)-1-[4-(Benzyloxy)-3-Nitrophenyl]-2-Bromoethanol
C15H14BrNO4 (351.01061440000007)
Analgin
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents D058633 - Antipyretics
(R)-1-(4-Benzyloxy-3-nitrophenyl)-2-bromoethanol
C15H14BrNO4 (351.01061440000007)
Ethyl 4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxypiperidine-1-carboxylate
3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1-cyclohexan]-4(3H)-one
Ethyl4-(4-chloro-a,a,a-trifluoro-m-tolylo)-4-hxdroxy-1-piperidinecarbxylate
4-bromo-5-((4-hydroxyphenethylamino)Methyl)-2-Methoxyphenol
ethyl 2-piperazine-4-(3-chloro)phenyl thiazole-5-carboxylate
C16H18ClN3O2S (351.08081980000003)
1-[2-(4-CHLOROPHENYLTHIO)ACETYL]-4-PHENYLTHIOSEMICARBAZIDE
2-bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine
(3R,4S)-REL-1-BENZYL-4-(4-CHLOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
Phenol,4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-
C19H14ClN3O2 (351.07744940000003)
cis-Chlorprothixene hydrochloride
C18H19Cl2NS (351.06151940000007)
4-(2-Chlorophenoxy)-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine
3-[(2,4-dichlorophenoxy)methyl]-4-phenyl-1H-1,2,4-triazole-5-thione
C15H11Cl2N3OS (350.99998560000006)
5-(1,3-Benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid
3-amino-N-(2-chlorophenyl)-4-(pyrrolidin-1-yl)benzene-1-sulfonamide
C16H18ClN3O2S (351.08081980000003)
Benzenesulfonic acid, 5-[(4-amino-5-methoxy-2-methylphenyl)azo]-2-methoxy-
C15H17N3O5S (351.08888720000004)
2-(4-chlorophenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic Acid
C16H14ClNO4S (351.03320340000005)
5-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester
4-Chloro-5-{[5-(methylamino)-1,3,4-thiadiazol-2-yl]sulfanyl}-2-phenyl-2,3-dihydropyridazin-3-one
{3-[(5-Chloro-1,3-Benzothiazol-2-Yl)methyl]-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl}acetic Acid
2-[(7-Hydroxy-naphthalen-1-YL)-oxalyl-amino]-benzoic acid
1-(O-Carboxy-phenylamino)-1-deoxy-D-ribulose-5-phosphate
N-[(3-Chloro-2-hydroxy-5-nitrophenyl)carbamothioyl]benzamide
2,5-Diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5-phosphate
C9H14N5O8P-2 (351.05799740000003)
5-Hydroxymethylcytidine 5-phosphate
C10H14N3O9P-2 (351.04676440000003)
3-(2-Formyl-6-hydroxy-4-methylphenyl)-8-hydroxy-1,4-dioxonaphthalene-2-carboxylate
2-[(2,3,4-Trihydroxy-5-phosphonooxypentyl)amino]benzoic acid
(5e)-5-(Quinolin-6-Ylmethylidene)-2-[(Thiophen-2-Ylmethyl)amino]-1,3-Thiazol-4(5h)-One
[3-(2-Furanyl)-5-(thiophen-2-ylmethylamino)-1,2,4-triazol-1-yl]-(3-pyridinyl)methanone
C17H13N5O2S (351.07899180000004)
3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide
C15H17N3O3S2 (351.07112920000003)
4-nitro-N-[(1E)-1-(2-oxo-2H-chromen-3-yl)ethylidene]benzohydrazide
C18H13N3O5 (351.08551680000005)
[1-(4,5-Diphenyl-2-thienyl)ethylideneamino]thiourea
2-hydroxy-N-[[5-(3-nitrophenyl)furan-2-yl]methylideneamino]benzamide
C18H13N3O5 (351.08551680000005)
N-(6-acetyl-1,3-benzodioxol-5-yl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide
6-(4-bromo-3,5-dimethyl-1-pyrazolyl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine
6-(2-chlorophenyl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine
C19H14ClN3S (351.0596914000001)
6-(3-chlorophenyl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine
C19H14ClN3S (351.0596914000001)
N-[3-[[(4-nitrophenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide
C18H13N3O5 (351.08551680000005)
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxane-2-carboxylate
2-(1,3-dioxo-2-isoindolyl)-N-(4-methyl-1,3-benzothiazol-2-yl)acetamide
C18H13N3O3S (351.0677588000001)
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone
C17H13N5O2S (351.07899180000004)
1-[[[2-(Difluoromethoxy)phenyl]-oxomethyl]amino]-3-(3-methylphenyl)thiourea
4-[4-[(1-Methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]benzonitrile
N-[(E)-(2,4-dihydroxyphenyl)methylideneamino]-4-methyl-3-nitrobenzenesulfonamide
C14H13N3O6S (351.05250380000007)
methyl 1-(4-chlorophenyl)-5-[(E)-(methylcarbamothioylhydrazinylidene)methyl]pyrazole-4-carboxylate
N-[(2R)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide
[3-Hydroxy-5-oxo-2-(3-sulfooxyphenyl)chromen-7-yl]oxidanium
C15H11O8S+ (351.01746260000004)
3-hydroxy-2-(3-methoxyphenyl)-7-sulinooxy-3,4-dihydro-2H-chromen-5-olate
3-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-sulino-3,4-dihydro-2H-chromen-5-olate
Tosylphenylalanyl chloromethyl ketone
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015842 - Serine Proteinase Inhibitors D009676 - Noxae > D000477 - Alkylating Agents > D000590 - Amino Acid Chloromethyl Ketones D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
2-Methyl-N-(5-methyl-2-thiazolyl)-1,1,4-trioxo-3H-1$l^{6},2-benzothiazine-3-carboxamide
2,5-diamino-4-hydroxy-6-(5-phosphonatoribosylamino)pyrimidine(3-)
C9H14N5O8P (351.05799740000003)
Dianion of 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine.
2-(4-bromophenyl)propanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester
2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5-phosphate(2-)
C9H14N5O8P (351.05799740000003)
The dianion formed by removal of two protons from the phosphate group of 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5-phosphate.
RO 4938581
RO 4938581 is a potent and selective GABAA α5 inverse agonist, with a Ki of 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively); RO 4938581 is used in the research of cognitive dysfunction.
VU 0238429
VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5), with an EC50 of 1.16 μM.
Wu-5
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD degradation and induce apoptosis[1].
(3r,4s,5s,10s)-4-hydroxy-9-thia-11,15,20-triazaheptacyclo[12.6.1.1³,¹⁰.0²,¹².0³,⁸.0⁵,²⁰.0¹⁷,²¹]docosa-1,7,11,14(21),16-pentaene-6,13-dione
C18H13N3O3S (351.0677588000001)
16-hydroxy-7,17-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-one
5-hydroxy-9-thia-11,15,20-triazaheptacyclo[12.6.1.1³,¹⁰.0²,¹².0³,⁸.0⁵,²⁰.0¹⁷,²¹]docosa-1,7,11,14(21),16-pentaene-6,13-dione
C18H13N3O3S (351.0677588000001)
methyl 5,13-dichloro-10-hydroxy-4-methyl-2-oxa-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,9,11,13-heptaene-7-carboxylate
C16H11Cl2NO4 (351.00651060000007)
17-hydroxy-7,16-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1,6,8,10,12(20),14(19),15,17-octaen-13-one
(1r,14s,19s,21s)-20-oxa-15-thia-4,9,13-triazaheptacyclo[12.7.1.1³,⁷.0¹,¹⁶.0²,¹².0¹⁹,²¹.0¹⁰,²³]tricosa-2(12),3,7,10(23),16-pentaene-11,18-dione
C18H13N3O3S (351.0677588000001)
20-oxa-15-thia-4,9,13-triazaheptacyclo[12.7.1.1³,⁷.0¹,¹⁶.0²,¹².0¹⁹,²¹.0¹⁰,²³]tricosa-2(12),3,7,10(23),16-pentaene-11,18-dione
C18H13N3O3S (351.0677588000001)
4-hydroxy-2-methyl-n-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ⁶,2-benzothiazine-3-carboximidic acid
17-hydroxy-7,18-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1,6,8,10,12(20),14(19),15,17-octaen-13-one
methyl 4-bromo-12-imino-7-oxo-5,8,11,13-tetraazatricyclo[8.4.0.0²,⁶]tetradeca-1(10),2(6),3,13-tetraene-14-carboxylate
C12H10BrN5O3 (350.99669700000004)