Exact Mass: 234.9863
Exact Mass Matches: 234.9863
Found 251 metabolites which its exact mass value is equals to given mass value 234.9863,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Pamidronate
Pamidronate is only found in individuals that have used or taken this drug.Pamidronate, marketed as pamidronate disodium pentahydrate under the brand name Aredia, is a bisphosphonate. [Wikipedia]The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may directly block dissolution of this mineral component of bone. In vitro studies also suggest that inhibition of osteoclast activity contributes to inhibition of bone resorption. Pamidronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass. M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization > M05BA - Bisphosphonates C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates
LY404039
LY404039 is a potent, selective and orally active mGluR2 and mGluR3 agonist with Kis of 149 nM and 92 nM for recombinant human mGluR2 and mGluR3, respectively. LY404039 shows >100-fold selectivity for mGluR2/3 over other receptors/transproters. LY404039 has antipsychotic and anxiolytic effects[1].
2,5-Dichloro-3-nitrobenzoic acid
CONFIDENCE standard compound; INTERNAL_ID 565; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3963; ORIGINAL_PRECURSOR_SCAN_NO 3959 CONFIDENCE standard compound; INTERNAL_ID 565; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3967; ORIGINAL_PRECURSOR_SCAN_NO 3964
5-(4-Methoxybenzylidene)-1,3-thiazolidine-2,4-dione
alpha-(Chloromethyl)-2-hydroxymethyl-5-nitroimidazole-1-ethanol
(4R)-3-((2S)-3-Mercapto-2-methylpropanoyl)-4-thiazolidinecarboxylic acid
Esterase
Esterase belongs to alkaloids and derivatives class of compounds. Those are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic propertiesand is also some synthetic compounds of similar structure are attributed to alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus. Esterase can be found in a number of food items such as fig, cabbage, wild leek, and white cabbage, which makes esterase a potential biomarker for the consumption of these food products. A wide range of different esterases exist that differ in their substrate specificity, their protein structure, and their biological function . C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist
Esterase
C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist
Arecoline hydrobromide
C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist
2-methyl-6-methylthioisoquinoline-3,5,8(2H)-trione
Esterase
C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist
Methyl 3-amino-4-(methylsulfonyl)thiophene-2-carboxylate
6-chloro-5-ethoxypyridine-2-carboximidamide,hydrochloride
3-chloro-6-ethoxypyridine-2-carboximidamide,hydrochloride
7-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-amine
(s)-(+)-2-chlorophenylglycine methyl ester hydrochloride
methyl 3-(methylsulfonamido)thiophene-2-carboxylate
8-hydroxy-4,5,6-trioxo-1H-quinoline-2-carboxylic acid
6-chloro-[1,3]dioxolo[4,5-g]quinoline-7-carbaldehyde
3-Bromo-1-azetidinecarboxylic acid tert-butyl ester
5-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
5-acetyl-3,4-dimethylthieno[2,3-b]thiophene-2-carbonitrile
2-MERCAPTO-6-OXO-4-(2-THIENYL)-1,6-DIHYDROPYRIMIDINE-5-CARBONITRILE
1-(4-CHLOROPHENYL)-2,5-DIMETHYL-1H-PYRROLE-3-ACETICACI
2-Quinoxalinecarboxylicacid, 3,4-dihydro-7-nitro-3-oxo-
4-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-amine
7-AMINO-3,4-DIHYDRO-1H-QUINOXALIN-2-ONE DIHYDROCHLORIDE
1,2-Benzisoxazole-3-methanesulfonic acid sodium salt
Lazabemide hydrochloride
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors C471 - Enzyme Inhibitor > C667 - Monoamine Oxidase Inhibitor
2-[4-(1,2,3-THIADIAZOL-4-YL)PHENYL]ETHANETHIOAMIDE
(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oicacid
D-2-Chlorophenylglycine methyl ester hydrochloride
7-FLUOROBENZO-2-OXA-1,3-DIAZOLE-4-SULFONIC ACID AMMONIUM SALT
4-methyl-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-3H-1,3-thiazole-5-carboxylic acid
Methyl 5-(aminomethyl)-2-chlorobenzoate hydrochloride
Ethyl 5-amino-2,6-dichloropyrimidine-4-carboxylate
N(pros)-phospho-L-histidine
A histidine derivative in which L-histidine has been phosphorylated on the pros N atom.
5-(4-Methoxybenzylidene)-1,3-thiazolidine-2,4-dione
4-Thiazolidinecarboxylic acid, 3-(3-mercapto-2-methyl-1-oxopropyl)-
1-[5-(Trifluoromethyl)pyridin-2-yl]sulfanylpropan-2-one
PAMIDRONIC ACID
M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization > M05BA - Bisphosphonates C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates
