Exact Mass: 234.957

Pamidronate

C3H11NO7P2 (235.0011)

Pamidronate is only found in individuals that have used or taken this drug.Pamidronate, marketed as pamidronate disodium pentahydrate under the brand name Aredia, is a bisphosphonate. [Wikipedia]The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may directly block dissolution of this mineral component of bone. In vitro studies also suggest that inhibition of osteoclast activity contributes to inhibition of bone resorption. Pamidronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass. M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization > M05BA - Bisphosphonates C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates

2,5-Dichloro-3-nitrobenzoic acid

C7H3Cl2NO4 (234.9439)

CONFIDENCE standard compound; INTERNAL_ID 565; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3963; ORIGINAL_PRECURSOR_SCAN_NO 3959 CONFIDENCE standard compound; INTERNAL_ID 565; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3967; ORIGINAL_PRECURSOR_SCAN_NO 3964

4-Nitrocatechol sulfate

C6H5NO7S (234.9787)

4-Chloro-3-sulfamoylbenzoic acid

C7H6ClNO4S (234.9706)

6-Deamino-6beta-chloro-6-Aminopenicillanic acid

C8H10ClNO3S (235.007)

DICHLOROVERONGIAQUINOL

C8H7Cl2NO3 (234.9803)

A natural product found in Suberea mollis.

5-Bromo-2H-chromene-3-carbonitrile

C10H6BrNO (234.9633)

Pyridinium, 1,2-dimethyl-, iodide

C7H10IN (234.9858)

4-Iodo-2-methoxypyridine

C6H6INO (234.9494)

5-chloro-2-methoxy-4-methylbenzenesulfonamide

C8H10ClNO3S (235.007)

(R)-(+)-1-(4-BROMOPHENYL)ETHYLAMINE HYDROCHLORIDE

C8H11BrClN (234.9763)

4-BROMOQINOLINE-2-CARBOXALDEHYDE

C10H6BrNO (234.9633)

4-Bromo-5,8-dimethylquinoline

C11H10BrN (234.9997)

4-Bromo-6,8-dimethylquinoline

C11H10BrN (234.9997)

3-chloro-N-(4-chloro-2-fluorophenyl)propanamide

C9H8Cl2FNO (234.9967)

6-bromoquinoline-3-carbaldehyde

C10H6BrNO (234.9633)

3-Bromo-5-chloro-2-methoxyaniline

C7H7BrClNO (234.94)

5-Bromopicolinimidamide hydrochloride

C6H7BrClN3 (234.9512)

6-BROMOPICOLINIMIDAMIDE HYDROCHLORIDE

C6H7BrClN3 (234.9512)

(5-Iodopyridin-3-yl)-methanol

C6H6INO (234.9494)

3,6-DICHLOROCARBAZOLE

C12H7Cl2N (234.9956)

Benzenesulfonic acid,2-amino-5-chloro-4-ethyl-

C8H10ClNO3S (235.007)

Methyl 3-amino-4-(methylsulfonyl)thiophene-2-carboxylate

C7H9NO4S2 (234.9973)

2-(2-Chloroethoxy)benzenesulfonamide

C8H10ClNO3S (235.007)

4-Bromobenzenesulfonamide

C6H6BrNO2S (234.9303)

2,4-Dichloro-3-ethyl-6-nitrophenol

C8H7Cl2NO3 (234.9803)

5-Bromo-2-chloro-4-ethoxypyridine

C7H7BrClNO (234.94)

4-(2,6-dichlorophenyl)-3-thiosemicarbazide

C7H7Cl2N3S (234.9738)

4-(2,5-Dichlorophenyl)-3-thiosemicarbazide

C7H7Cl2N3S (234.9738)

2-(3,4-Dichlorophenyl)-1-hydrazinecarbothioamide

C7H7Cl2N3S (234.9738)

5-(aminosulfonyl)-2-chlorobenzoic acid

C7H6ClNO4S (234.9706)

1-(3-Bromophenyl)-cyclobutanecarbonitrile

C11H10BrN (234.9997)

2-nitro-alpha-toluenesulfonyl chloride

C7H6ClNO4S (234.9706)

3-bromopyridine-2-carboximidamide,hydrochloride

C6H7BrClN3 (234.9512)

Taurosteine

C7H9NO4S2 (234.9973)

C78273 - Agent Affecting Respiratory System > C74536 - Mucolytic Agent

4-BROMOPICOLINIMIDAMIDE HYDROCHLORIDE

C6H7BrClN3 (234.9512)

2,4-dichloro-3,5-dimethyl-6-nitrophenol

C8H7Cl2NO3 (234.9803)

2-Bromo-4-fluoro-5-nitrophenol

C6H3BrFNO3 (234.928)

Carbocloral

C5H8Cl3NO3 (234.957)

C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic

3-Amino-4-iodophenol

C6H6INO (234.9494)

2-Amino-5-iodophenol

C6H6INO (234.9494)

4-Bromo-2-fluoro-6-nitrophenol

C6H3BrFNO3 (234.928)

3-bromo-5-chloro-2-methoxy-4-methylpyridine

C7H7BrClNO (234.94)

TCMDC-123819

C6H6BrNO2S (234.9303)

3-Iodo-2-methoxypyridine

C6H6INO (234.9494)

5-iodo-4-methyl-1H-pyridin-2-one

C6H6INO (234.9494)

2-Bromo-5-(methylsulfonyl)pyridine

C6H6BrNO2S (234.9303)

Benzenesulfonamide,4-chloro-N-(2-hydroxyethyl)-

C8H10ClNO3S (235.007)

1-[4-(bromomethyl)phenyl]pyrrole

C11H10BrN (234.9997)

(4-bromo-6-chloropyridin-3-yl)boronic acid

C5H4BBrClNO2 (234.9207)

2-ACETYL-4-IODOPYRROLE

C6H6INO (234.9494)

2,6-DICHLORO-3-NITROBENZOIC ACID

C7H3Cl2NO4 (234.9439)

Ethyl 4-bromo-1,3-thiazole-5-carboxylate

C6H6BrNO2S (234.9303)

(1-BENZYL-PYRROLIDIN-3-YLMETHYL)-METHYL-AMINE

C11H10BrN (234.9997)

4-Bromo-2-fluoro-5-nitrophenol

C6H3BrFNO3 (234.928)

4-Bromo-5-fluoro-2-nitrophenol

C6H3BrFNO3 (234.928)

5-(Trifluoromethyl)benzo[d]thiazole-2(3H)-thione

C8H4F3NS2 (234.9737)

Disodium nitrilotriacetate

C6H7NNa2O6 (235.0069)

1-HYDROXY-2 5-DIOXO-3-PYRROLIDINESULFON

C4H6NNaO7S (234.9763)

1-(2-BROMOPHENYL)-CYCLOBUTANECARBONITRILE

C11H10BrN (234.9997)

2-bromo-6-(methylsulfonyl)pyridine

C6H6BrNO2S (234.9303)

4-bromo-2,6-difluorobenzamide

C7H4BrF2NO (234.9444)

methyl 3-(methylsulfonamido)thiophene-2-carboxylate

C7H9NO4S2 (234.9973)

2-CHLORO-4-CYANOBENZENESULFONYL CHLORIDE

C7H3Cl2NO2S (234.9262)

3-Nitro-4-chlorophenyl methyl sulfone

C7H6ClNO4S (234.9706)

5-iodopyridine-2,3-diamine

C5H6IN3 (234.9606)

4-azido-2,3,5,6-tetrafluorobenzoic acid

C7HF4N3O2 (235.0005)

5-IODO-6-METHYL-4-PYRIMIDIN AMINE

C5H6IN3 (234.9606)

3-Chloro-4-(methylsulfonyl)nitrobenzene

C7H6ClNO4S (234.9706)

4-chloro-2-nitrophenylmethyl sulphone

C7H6ClNO4S (234.9706)

4-(1-aminoethyl)-2-fluorophenol(SALTDATA: HBr)

C8H11BrFNO (235.0008)

N-Methyl-3-bromobenzylamine Hydrochloride

C8H11BrClN (234.9763)

2-Amino-6-iodophenol

C6H6INO (234.9494)

6-bromoquinoline-2-carbaldehyde

C10H6BrNO (234.9633)

6-Bromo-2,8-dimethylquinoline

C11H10BrN (234.9997)

2-Bromo-3-chloropyridine-4-boronic acid

C5H4BBrClNO2 (234.9207)

3-Methyl-5-nitrophenylsulfonyl chloride

C7H6ClNO4S (234.9706)

5-Iodo-2-methoxypyridine

C6H6INO (234.9494)

4-Bromo-2,8-dimethylquinoline

C11H10BrN (234.9997)

5-Bromo-2-(methylsulfonyl)pyridine

C6H6BrNO2S (234.9303)

8-Bromoquinoline-4-carbaldehyde

C10H6BrNO (234.9633)

5-iodo-3-methyl-2-pyridinol

C6H6INO (234.9494)

2,6-Diamino-3-iodopyridine

C5H6IN3 (234.9606)

(4-Nitrophenyl)methanesulfonyl chloride

C7H6ClNO4S (234.9706)

1-(4-BROMOPHENYL)CYCLOBUTANECARBONITRILE

C11H10BrN (234.9997)

Methyl 5-bromo-2-methyl-1,3-thiazole-4-carboxylate

C6H6BrNO2S (234.9303)

7-bromoquinoline-3-carbaldehyde

C10H6BrNO (234.9633)

5-Iodo-6-methylpyridin-2-ol

C6H6INO (234.9494)

2-Iodo-6-Methylpyridin-4-ol

C6H6INO (234.9494)

4-Bromo-2,3-dimethylaniline hydrochloride (1:1)

C8H11BrClN (234.9763)

4-trifluoromethylthiophenyl isothiocyan&

C8H4F3NS2 (234.9737)

3-Iodo-5-methoxypyridine

C6H6INO (234.9494)

ETHYL 4-BROMOTHIAZOLE-2-CARBOXYLATE

C6H6BrNO2S (234.9303)

6-chloro-[1,3]dioxolo[4,5-g]quinoline-7-carbaldehyde

C11H6ClNO3 (235.0036)

2-Methyl-3-hydroxy-6-iodopyridine

C6H6INO (234.9494)

2,3-dichloro-6-nitrobenzoic acid

C7H3Cl2NO4 (234.9439)

4-BROMO-5-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID

C4H2BrN3O4 (234.9229)

Methyl 2-bromo-5-methylthiazole-4-carboxylate

C6H6BrNO2S (234.9303)

Methyl 5-bromo-4-methylthiazole-2-carboxylate

C6H6BrNO2S (234.9303)

Imidazo[1,2-a]pyridine-3-acetonitrile-8-bromo

C9H6BrN3 (234.9745)

2-AMINO-5-IODO-3-METHYLPYRAZINE

C5H6IN3 (234.9606)

2-(2,4-dichlorophenoxy)ethanethioamide

C8H7Cl2NOS (234.9625)

2-(3,5-dichlorophenoxy)ethanethioamide

C8H7Cl2NOS (234.9625)

2-BROMOQUINOLINE-4-CARBOXALDEHYDE

C10H6BrNO (234.9633)

2-Methyl-5-nitrobenzenesulfonyl chloride

C7H6ClNO4S (234.9706)

3-Bromo-5-chloro-4-methoxyaniline

C7H7BrClNO (234.94)

3-Bromo-N,4-dimethylaniline hydrochloride

C8H11BrClN (234.9763)

5-Bromo-N,2-dimethylaniline hydrochloride

C8H11BrClN (234.9763)

4-Bromo-N-ethylaniline hydrochloride

C8H11BrClN (234.9763)

6-bromoquinoline-4-carbaldehyde

C10H6BrNO (234.9633)

Pyridinium,1,4-dimethyl-, iodide (1:1)

C7H10IN (234.9858)

2-MERCAPTO-6-OXO-4-(2-THIENYL)-1,6-DIHYDROPYRIMIDINE-5-CARBONITRILE

C9H5N3OS2 (234.9874)

4-Iodo-1-methylpyridin-2(1H)-one

C6H6INO (234.9494)

2-(2,5-DICHLOROPHENOXY)THIOACETAMIDE

C8H7Cl2NOS (234.9625)

2-(2,3-DICHLOROPHENOXY)THIOACETAMIDE

C8H7Cl2NOS (234.9625)

2-BROMO-4-FLUORO-6-NITROPHENOL

C6H3BrFNO3 (234.928)

2-bromo-6-fluoro-4-nitrophenol

C6H3BrFNO3 (234.928)

2-Iodo-3-methoxypyridine

C6H6INO (234.9494)

METHYL 2-BROMO-4-METHYLTHIAZOLE-5-CARBOXYLATE

C6H6BrNO2S (234.9303)

2-Bromo-5-fluoro-3-nitropyridin-4-amine

C5H3BrFN3O2 (234.9393)

2,6-Dichloro-4-nitrobenzoic acid

C7H3Cl2NO4 (234.9439)

4-(trifluoromethylsulfonyl)benzonitrile

C8H4F3NO2S (234.9915)

4-amino-2-iodophenol

C6H6INO (234.9494)

4,6-DICHLORO-5-NITRONICOTINAMIDE

C6H3Cl2N3O3 (234.9551)

2-Bromo-4-chloro-6-methoxyaniline

C7H7BrClNO (234.94)

(2,6-Dichloro-3-nitrophenyl)boronic acid

C6H4BCl2NO4 (234.961)

2,4-DICHLORO-5-NITROPHENYLBORONIC ACID

C6H4BCl2NO4 (234.961)

methyl-(2e)-2-acetylamino-3-bromo-2-butenoate

C7H10BrNO3 (234.9844)

5-Bromo-2-thiazolecarboxylic acid ethyl ester

C6H6BrNO2S (234.9303)

2-Iodo-6-methoxypyridine

C6H6INO (234.9494)

Ethyl 2-bromothiazole-4-carboxylate

C6H6BrNO2S (234.9303)

Ethyl 5-bromothiazole-4-carboxylate

C6H6BrNO2S (234.9303)

2-chloro-4-sulfamoylbenzoic acid

C7H6ClNO4S (234.9706)

3-nitrophenylmethanesulfonyl chloride

C7H6ClNO4S (234.9706)

1-[3-(BROMOMETHYL)PHENYL]-1H-PYRROLE

C11H10BrN (234.9997)

6-(Bromomethyl)-2-methylquinoline

C11H10BrN (234.9997)

5-bromo-2-chloro-4-pyridineboronic acid

C5H4BBrClNO2 (234.9207)

4-BROMO-2-ETHYLANILINE HYDROCHLORIDE

C8H11BrClN (234.9763)

METHYL-(2Z)-2-ACETYLAMINO-3-BROMO-2-BUTENOATE

C7H10BrNO3 (234.9844)

2-(4-Bromophenyl)ethylamine hydrochloride

C8H11BrClN (234.9763)

2-methyl-4-nitrobenzenesulfonyl chloride

C7H6ClNO4S (234.9706)

2-Bromo-3-fluoro-5-nitrophenol

C6H3BrFNO3 (234.928)

Methyl 3-amino-5-bromo-2-thiophenecarboxylate

C6H6BrNO2S (234.9303)

rhenium trioxide

O3Re (234.9405)

6-Bromo-3-fluoro-2-nitrophenol

C6H3BrFNO3 (234.928)

7-bromoquinoline-4-carbaldehyde

C10H6BrNO (234.9633)

4-BROMO-PYRROLO[2,3-F]-7-AZAINDOLE

C9H6BrN3 (234.9745)

(3-bromo-6-chloro-4-methylpyridin-2-yl)methanol

C7H7BrClNO (234.94)

1-(2-bromo-4-methylphenyl)Pyrrole

C11H10BrN (234.9997)

1-(3-iodopropyl)pyrrole

C7H10IN (234.9858)

Ethyl 2-bromothiazole-5-carboxylate

C6H6BrNO2S (234.9303)

2-Iodo-6-methyl-3-pyridinol

C6H6INO (234.9494)

2-bromo-5-chloropyridine-4-boronic acid

C5H4BBrClNO2 (234.9207)

2-[(2,6-dichlorophenyl)methylsulfanyl]ethanamine

C9H11Cl2NS (234.9989)

4-(2,4-dichlorophenyl)-3-thiosemicarbazide

C7H7Cl2N3S (234.9738)

4-Bromo-2,6-dimethylquinoline

C11H10BrN (234.9997)

3-trifluoromethylthiophenyl isothiocyan&

C8H4F3NS2 (234.9737)

3-Chloro-4-cyano-benzenesulfonyl chloride

C7H3Cl2NO2S (234.9262)

3-Bromoquinoline-2-carbaldehyde

C10H6BrNO (234.9633)

7-Bromo-2,8-dimethylquinoline

C11H10BrN (234.9997)

5-bromo-4-methoxythiophene-3-carboxamide

C6H6BrNO2S (234.9303)

4-amino-3-iodophenol

C6H6INO (234.9494)

1,2-Benzisoxazole-3-methanesulfonic acid sodium salt

C8H6NNaO4S (234.9915)

AMINO-(3,5-DICHLORO-4-HYDROXY-PHENYL)-ACETIC ACID

C8H7Cl2NO3 (234.9803)

(4-bromo-1,3-thiazol-2-yl)-trimethylsilane

C6H10BrNSSi (234.9487)

5-bromoquinoline-8-carbaldehyde

C10H6BrNO (234.9633)

1-(2-Bromo-phenyl)-ethylamine hydrochloride

C8H11BrClN (234.9763)

3-Amino-4-bromo-benzaldehyde hydrochloride

C7H7BrClNO (234.94)

4-broMo-2,3-difluoro-N,N-diMethylaniline

C8H8BrF2N (234.9808)

4-Bromo-2-chloropyridine-3-boronic acid

C5H4BBrClNO2 (234.9207)

(1R)-1-(3-BROMOPHENYL)ETHANAMINE HCL

C8H11BrClN (234.9763)

3-MALEIMIDOBENZOIC ACID CHLORIDE

C11H6ClNO3 (235.0036)

4-METHYL-3-NITROBENZENESULFONYL CHLORIDE

C7H6ClNO4S (234.9706)

5-bromo-2-chloropyridin-3-ylboronic acid

C5H4BBrClNO2 (234.9207)

3-Iodo-4-methoxypyridine

C6H6INO (234.9494)

Methyl 3-amino-4-bromothiophene-2-carboxylate

C6H6BrNO2S (234.9303)

N-Methyl-4-bromobenzylamine Hydrochloride

C8H11BrClN (234.9763)

2-(6-Bromopyridin-3-yl)pyrimidine

C9H6BrN3 (234.9745)

2-Amino-3-iodophenol

C6H6INO (234.9494)

5-Bromo-2-chloro-4-(dimethylamino)pyrimidine

C6H7BrClN3 (234.9512)

5-Chloro-2-cyanobenzene-1-sulfonyl chloride

C7H3Cl2NO2S (234.9262)

2-Chloro-5-cyanobenzenesulfonyl chloride

C7H3Cl2NO2S (234.9262)

4-(Bromomethyl)-2-methylquinoline

C11H10BrN (234.9997)

2,3-dichloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid

C7H3Cl2NO2S (234.9262)

5-iodo-4-methylpyrimidin-2-amine

C5H6IN3 (234.9606)

1-(2-Bromoacetoxy)-2,5-pyrrolidinedione

C6H6BrNO4 (234.948)

2-Bromobenzenesulfonamide

C6H6BrNO2S (234.9303)

6-iodo-2-methylpyrimidin-4-amine

C5H6IN3 (234.9606)

7-FLUOROBENZO-2-OXA-1,3-DIAZOLE-4-SULFONIC ACID AMMONIUM SALT

C6H6FN3O4S (235.0063)

4-Bromo-6,7-dimethylquinoline

C11H10BrN (234.9997)

4-Bromo-6-ethylquinoline

C11H10BrN (234.9997)

4-Bromo-7,8-dimethylquinoline

C11H10BrN (234.9997)

4-Bromo-8-ethylquinoline

C11H10BrN (234.9997)

7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole

C11H10BrN (234.9997)

3-Bromo-5-(methylsulfonyl)pyridine

C6H6BrNO2S (234.9303)

2-Chloro-3-bromo-4-pyridineboronic acid

C5H4BBrClNO2 (234.9207)

4-bromo-2-chloro-5-methoxyaniline

C7H7BrClNO (234.94)

3-Bromo-7-quinolinecarbaldehyde

C10H6BrNO (234.9633)

Ethyl 5-amino-2,6-dichloropyrimidine-4-carboxylate

C7H7Cl2N3O2 (234.9915)

(5-FLUORO-2-NITRO-PHENYL)-ACETICACID

C5H6IN3 (234.9606)

(3,5-Dichloroanilino)thiourea

C7H7Cl2N3S (234.9738)

s-(3,4-Dichlorobenzyl) isothiourea

C8H9Cl2N2S+ (234.9863)

PAMIDRONIC ACID

C3H11NO7P2 (235.0011)

M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization > M05BA - Bisphosphonates C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates

2-(3,5-dichloro-1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)ethanimidic acid

C8H7Cl2NO3 (234.9803)