Exact Mass: 215.019488
Exact Mass Matches: 215.019488
Found 466 metabolites which its exact mass value is equals to given mass value 215.019488,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Glycerylphosphorylethanolamine
Glycerylphosphorylethanolamine is a membrane breakdown product resulting from the cleavage of the lipid group from glycerophosphoethanlomine fatty acids (i.e. phosphatidylethanolamine). It acts as a growth stimulant for hepatocytes. A membrane breakdown product resulting from the cleavage of the lipid group from glycerophosphoethanlomine fatty acids (i.e. phosphatidylethanolamine). It acts as a growth stimulant for hepatocytes. [HMDB]
O-Phospho-4-hydroxy-L-threonine
O-Phospho-4-hydroxy-L-threonine is involved in the vitamin B6 metabolism system. O-Phospho-4-hydroxy-L-threonine is a precursor for pyridoxine. O-Phospho-4-hydroxy-L-threonine can be converted to 4-hydroxy-L-threonine and 2-Amino-3-oxo-4-phosphonooxybutyrate by threonine synthase [EC:4.2.3.1] and 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262], respectively. [HMDB] O-Phospho-4-hydroxy-L-threonine is involved in the vitamin B6 metabolism system. O-Phospho-4-hydroxy-L-threonine is a precursor for pyridoxine. O-Phospho-4-hydroxy-L-threonine can be converted to 4-hydroxy-L-threonine and 2-Amino-3-oxo-4-phosphonooxybutyrate by threonine synthase [EC:4.2.3.1] and 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262], respectively.
Robustine
A quinoline alkaloid that is furo[2,3-b]quinoline substituted by a methoxy and a hydroxy group at positions 4 and 8 respectively. Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1]. Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].
AG-126
C10H5N3O3 (215.03309000000002)
D000970 - Antineoplastic Agents > D020032 - Tyrphostins D004791 - Enzyme Inhibitors AG126 is a tyrosine kinase inhibitor, can inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM. AG126 can be used in meiosis, mitosis, and postmitotic research[1][2][3][4].
3-Chlorotyrosine
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. (PMID 9151778). In particular, myeloperoxidase halogenates tyrosine residues in plasma proteins and and generates 3-chlorotyrosine (CY). The detection of free chlorotyrosine in blood or urine arises from the degradation of these chlorinated proteins. CY concentrations may be useful for monitoring the activation of neutrophils in asthmatic patients (PMID 15196282). 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. (PMID 9151778) [HMDB] D004791 - Enzyme Inhibitors 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
sn-glycero-3-Phosphoethanolamine
Sn-glycero-3-phosphoethanolamine is a substrate for: Lysoplasmalogenase. Glycerophosphoethanolamine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=1190-00-7 (retrieved 2024-07-25) (CAS RN: 1190-00-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
2-Amino-5,6-dichloro-3,4,-dihydroquinazoline
2-Amino-5,6-dichloro-3,4,-dihydroquinazoline is a metabolite of anagrelide. Anagrelide is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. (Wikipedia)
4-(2-Pyridylazo)resorcinol
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds D004396 - Coloring Agents
2-Amino-3-(3-fluoro-4,5-dihydroxyphenyl)propanoic acid
2-Amino-3-(2-fluoro-3,4-dihydroxyphenyl)propanoic acid
6-Oxo-1-phenyl-1,6-dihydropyridine-3-carboxylic acid
8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine
C10H11Cl2N (215.02685060000002)
Tyrphostin AG 126
C10H5N3O3 (215.03309000000002)
D000970 - Antineoplastic Agents > D020032 - Tyrphostins D004791 - Enzyme Inhibitors AG126 is a tyrosine kinase inhibitor, can inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM. AG126 can be used in meiosis, mitosis, and postmitotic research[1][2][3][4].
Naftazone
C - Cardiovascular system > C05 - Vasoprotectives > C05C - Capillary stabilizing agents D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics C78275 - Agent Affecting Blood or Body Fluid > C78311 - Hemostatic Agent
(2S)-2-(Chloroamino)-3-(4-hydroxyphenyl)propanoic Acid
Sodium dihydrogen citrate
Preservative. Monosodium citrate, or sodium dihydrogen citrate, is an acid salt with the chemical formula NaH2C6H5O7, or C3H4OH(COOH)2COONa. Since it has two remaining open spots on the citrate anion, it is used as a relatively strong sequestrant. It is used to prevent platelet clumping in blood samples. It is one of the 3 citric acid salts. Preservative
Fluorodopa F 18
V - Various > V09 - Diagnostic radiopharmaceuticals > V09I - Tumour detection C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
Sulfacarbamide
C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Methyl 2-sulfamoylbenzoate
CONFIDENCE standard compound; EAWAG_UCHEM_ID 126
dimethyl 3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate
4-(2-Pyridylazo)resorcinol
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D002863 - Chromogenic Compounds D004396 - Coloring Agents
5-hydroxy-4-methoxyfuro[2,3-b]quinoline|5-hydroxydictamnine
(E)-4-hydroxy-2,2-bipyridine-6-carbaldehyde oxime|caerulomycin H
Tox21_302002
D-(+)-Galactosamine hydrochloride is a hexose.
3-Chloro-L-tyrosine
A chloroamino acid comprising a tyrosine core with a chloro- substituent ortho to the phenolic hydroxy group. D004791 - Enzyme Inhibitors Acquisition and generation of the data is financially supported in part by CREST/JST. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
2-Benzothiazolesulfonic acid
CONFIDENCE standard compound; INTERNAL_ID 2873 CONFIDENCE standard compound; INTERNAL_ID 8826 CONFIDENCE standard compound; INTERNAL_ID 8201
2-Benzothiazolsulfonic acid
CONFIDENCE standard compound; INTERNAL_ID 4209 INTERNAL_ID 4209; CONFIDENCE standard compound
3-Chlorotyrosine
3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Monochlorotyrosine
D004791 - Enzyme Inhibitors 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
N4-Benzoylcytosine
N4-Benzoylcytosine is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].
(1R)-6,7-dichloro-1,2,3,4-tetrahydronaphthalen-1-amine
C10H11Cl2N (215.02685060000002)
methyl 6-cyano-1-methylpyrrolo[3,2-b]pyridine-2-carboxylate
5-Bromo-1-isopropylpyridin-2(1H)-one
C8H10BrNO (214.99457099999998)
Benzenamine, 5-bromo-2-methoxy-4-methyl- (9CI)
C8H10BrNO (214.99457099999998)
3-ALLYL-4-AMINO-2-THIOXO-2,3-DIHYDRO-1,3-THIAZOLE-5-CARBOXAMIDE
4-AMINO-N-(TETRAHYDRO-2-FURANYLMETHYL)BENZAMIDE
C10H11ClFNO (215.05131579999997)
(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol,hydrochloride
(2-CHLORO-PYRIMIDIN-4-YLMETHYL)-ISOPROPYL-AMINE
C8H10BrNO (214.99457099999998)
2-(4-Bromopyridin-2-yl)propan-2-ol
C8H10BrNO (214.99457099999998)
(3-bromo-5-methoxyphenyl)methanamine
C8H10BrNO (214.99457099999998)
(3-bromo-4-methoxyphenyl)methanamine
C8H10BrNO (214.99457099999998)
3-(METHYLTHIO)-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE
2-amino-4,5-methylenedioxyacetophenone hydrochloride
(S)-2-AMINO-3-(2-CHLORO-4-HYDROXYPHENYL)PROPANOIC ACID
N-(3-METHOXYPHENYL)-N-METHYLTHIOCARBAMOYL CHLORIDE
2-(5-Amino-[1,3,4]thiadiazol-2-ylsulfanyl)-1-cyclopropyl-ethanone
Ethyl 4-chloro-1-methyl-6-oxo-dihydropyridine-3-carboxylate
2-chloro-6-propan-2-yloxypyridine-4-carboxylic acid
N-(4-METHOXYPHENYL)-N-METHYLTHIOCARBAMOYL CHLORIDE
3-chloro-N-(2-fluoro-5-methylphenyl)propanamide
C10H11ClFNO (215.05131579999997)
5-Bromo-N-4-ethyl-pyridine-3,4-diamine
C7H10BrN3 (215.00580399999998)
4-Pyridinecarboxylicacid, 2-(2-furanylmethylene)hydrazide
Methyl 3-amino-4-chloro-5-methoxybenzenecarboxylate
6-Nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
C10H5N3O3 (215.03309000000002)
7-Nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
C10H5N3O3 (215.03309000000002)
Trimethylphenylammonium bromide
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
5,7-dichloro-3,4-dihydro-2H-isoquinolin-1-one
C9H7Cl2NO (214.99046719999998)
6-oxo-1,2-dihydro-6h-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid
4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-5-nitro-2,6-dioxo-, methyl ester
(5-bromo-2-methoxyphenyl)methanamine
C8H10BrNO (214.99457099999998)
2-HYDRAZONO-3-METHYL-2,3-DIHYDROBENZO[D]THIAZOLE HYDROCHLORIDE
Pyridine,4-bromo-6-methoxy-2,3-dimethyl-
C8H10BrNO (214.99457099999998)
Tiamenidine
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
5-OXO-1-PYRIDIN-2-YLMETHYL-PYRROLIDINE-3-CARBOXYLIC ACID
4-Bromo-2-methylaminomethyl-phenol
C8H10BrNO (214.99457099999998)
1-(4-Bromophenyl)-N-methoxymethanamine
C8H10BrNO (214.99457099999998)
(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)BORONIC ACID
C8H5BF3NO2 (215.03654160000002)
2-OXO-6-PHENYL-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID
2-fluoro-3,3-dimethyl-1,2-benzothiazole 1,1-dioxide
C9H10FNO2S (215.04162520000003)
6-Bromo-3-methoxy-2,4-dimethylpyridine
C8H10BrNO (214.99457099999998)
4-Chloro-5-(methylsulfinyl)-7H-pyrrolo[2,3-d]pyrimidine
3-(bromomethyl)-6-methoxy-2-methylpyridine
C8H10BrNO (214.99457099999998)
5H-CYCLOHEPTA[C]PYRIDINE, 1,3-DICHLORO-6,7,8,9-TETRAHYDRO-
C10H11Cl2N (215.02685060000002)
5-(methylthio)pyridin-3-ylthiomethylboronic acid 95
(Z)-ETHYL 2-(2-AMINOTHIAZOL-4-YL)-2-(HYDROXYIMINO)ACETATE
3-chloro-N-(3-fluoro-4-methylphenyl)propanamide
C10H11ClFNO (215.05131579999997)
(2-CYANO-4-(TRIFLUOROMETHYL)PHENYL)BORONIC ACID
C8H5BF3NO2 (215.03654160000002)
8-nitro-4-oxo-1H-quinoline-3-carbonitrile
C10H5N3O3 (215.03309000000002)
3-Bromo-6-methoxy-2,4-dimethylpyridine
C8H10BrNO (214.99457099999998)
2-(methylthio)thiazolo[4,5-d]pyrimidine-5,7-diol
C6H5N3O2S2 (214.98231900000002)
Isoquinoline, 7,8-dichloro-1,2,3,4-tetrahydro-4-methyl- (9CI)
C10H11Cl2N (215.02685060000002)
4-(Methanesulfonylamino)benzoic acid
COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
3-chloro-N-(5-fluoro-2-methylphenyl)propanamide
C10H11ClFNO (215.05131579999997)
1,3-dichloro-2-(2-isocyanatoethyl)benzene
C9H7Cl2NO (214.99046719999998)
1,2-dichloro-4-(2-isocyanatoethyl)benzene
C9H7Cl2NO (214.99046719999998)
5-bromo-2-(isopropylamino)pyrimidine
C7H10BrN3 (215.00580399999998)
3-Quinolinecarbonitrile, 1,4-dihydro-7-nitro-4-oxo-
C10H5N3O3 (215.03309000000002)
5-Nitro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile
C10H5N3O3 (215.03309000000002)
5,6,7,8-TETRAHYDROPYRIDO[3,4-B]PYRAZINE-7-CARBOXYLIC ACID HYDROCHLORIDE
Cosamin
(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride is an endogenous metabolite.
5-Chloro-3-(3,5-difluorophenyl)isoxazole
C9H4ClF2NO (214.99494679999998)
2-(5-chloropyridin-2-yl)oxy-2-methylpropanoic acid
2-(4-bromopyridin-3-yl)propan-2-ol
C8H10BrNO (214.99457099999998)
METHYL 6-(TRIFLUOROMETHYL)-2,3-DIHYDRO-1H-INDOL-5-YL ETHER
ETHYL 4-CHLORO-1-METHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
2-(6-bromopyridin-2-yl)propan-2-ol
C8H10BrNO (214.99457099999998)
5-Chloro-4-fluoro-3-nitro-1H-pyrrolo[2,3-b]pyridine
2-CHLORO-5,5-DIMETHYL-5,6-DIHYDROBENZO[D]THIAZOL-7(4H)-ONE
2-Chloro-N-[2-(2-fluorophenyl)ethyl]acetamide
C10H11ClFNO (215.05131579999997)
2-(Bromomethyl)-3-methoxy-6-methylpyridine
C8H10BrNO (214.99457099999998)
BENZO-2,1,3-THIADIAZOLE-4-SULPHONAMIDE
C6H5N3O2S2 (214.98231900000002)
1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-(cyanomethyl)-, Methyl ester
4-BROMO-2,3,5-TRIMETHYLPYRIDINE 1-OXIDE
C8H10BrNO (214.99457099999998)
(3-bromo-2-methoxyphenyl)methanamine
C8H10BrNO (214.99457099999998)
Glucopyranose,6-amino-6-deoxy-, hydrochloride, D- (6CI,8CI)
2-(5-Bromo-2-pyridinyl)-2-propanol
C8H10BrNO (214.99457099999998)
2,3-DIHYDROBENZO[B][1,4]DIOXINE-6-CARBOXAMIDE HYDROCHLORIDE
5,7-dichloro-2,3-dihydro-1H-quinolin-4-one
C9H7Cl2NO (214.99046719999998)
Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate
8-CYANO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
3-CHLORO-N-(4-FLUORO-BENZYL)-PROPIONAMIDE
C10H11ClFNO (215.05131579999997)
(R/S)-4-(Aminomethyl)-3-pyrrolidinone O-Methyloxime Dichloride
C6H15Cl2N3O (215.05921199999997)
4-CHLORO-2-(METHYLTHIO)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDINE
5-Amino-2-chloro-4-Methoxy-benzoic acid Methyl ester
(R)-2-amino-2-(4-bromophenyl)ethanol
C8H10BrNO (214.99457099999998)
(R)-4-Bromo-1-pyrrolidin-3-yl-1H-pyrazole
C7H10BrN3 (215.00580399999998)
(2S)-2-(2,6-DICHLOROPHENYL)PYRROLIDINE
C10H11Cl2N (215.02685060000002)
(S)-4-Bromo-1-pyrrolidin-3-yl-1H-pyrazole
C7H10BrN3 (215.00580399999998)
2,3-Diamino-4,6-dimethyl-5-bromopyridine
C7H10BrN3 (215.00580399999998)
3-Methyl-2-Benzothiazolinone Hydrazone Hydrochloride
6-Chloro-N-cyclopropyl-2-(methylthio)pyrimidin-4-amine
N-Cyclopropyl-4-fluorobenzenesulfonamide
C9H10FNO2S (215.04162520000003)
N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine
C7H10BrN3 (215.00580399999998)
2-Oxo-5-phenyl-1,2-dihydropyridine-3-carboxylic acid
3-(dimethylamino)azetidine-3-carboxamide,dihydrochloride
C6H15Cl2N3O (215.05921199999997)
2-amino-4-bromo-3,5-dimethylphenol
C8H10BrNO (214.99457099999998)
3-AMINO-3-(3-CHLORO-4-HYDROXY-PHENYL)-PROPIONIC ACID
2,4-dichloro-1-(2-isocyanatoethyl)benzene
C9H7Cl2NO (214.99046719999998)
1-(benzotriazol-1-yl)-2,2,2-trifluoroethanone
C8H4F3N3O (215.03064499999996)
Ethyl 3-(methylsulfanyl)-5-oxo-2,5-dihydro-1,2,4-triazine-6-carboxylate
D-Glucosamine hydrochloride
Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
4-OXO-1,2-DIHYDRO-4H-PYRROLO[3,2,1-IJ]QUINOLINE-5-CARBOXYLICACID
Carisbamate
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics
Phosphoric acid, MONO(2-aminoethyl) mono((2S)-2,3-dihydroxypropyl) ester
8-Methyl-1,5-dihydropyrimido[5,4-b]indole-4-thione
7,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline
C10H11Cl2N (215.02685060000002)
2,7-Dimethyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Fluorodopa F-18
V - Various > V09 - Diagnostic radiopharmaceuticals > V09I - Tumour detection C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
naftazone
C - Cardiovascular system > C05 - Vasoprotectives > C05C - Capillary stabilizing agents D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics C78275 - Agent Affecting Blood or Body Fluid > C78311 - Hemostatic Agent
Sodium dihydrogen citrate
Preservative. Monosodium citrate, or sodium dihydrogen citrate, is an acid salt with the chemical formula NaH2C6H5O7, or C3H4OH(COOH)2COONa. Since it has two remaining open spots on the citrate anion, it is used as a relatively strong sequestrant. It is used to prevent platelet clumping in blood samples. It is one of the 3 citric acid salts. Preservative
2-(Acetamidomethylene)-3-(hydroxymethyl)succinate
C8H9NO6-2 (215.04298540000002)
(2,6-Difluoro-4-hydroxyphenyl)pyruvate
C9H5F2O4- (215.01558939999998)
3-chloro-L-tyrosine zwitterion
An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 3-chloro-L-tyrosine; major species at pH 7.3.
[2,3-Dihydroxypropyl(2-hydroxyethyl)amino]phosphonic acid
[2-Chloroethyl-[(2-chloroethylamino)-oxomethyl]amino]-oxidoammonium
C5H11Cl2N3O2 (215.02282860000003)
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
6-fluoro-L-dopa
A non-proteinognic L-alpha-amino acid that is L-alanine in which one of the hydrogens of the methyl group has been replaced by a 2-fluoro-4,5-dihydroxyphenyl group.
caerulomycin H
A pyridine alkaloid that is 2,2-bipyridine substituted by a hydroxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity.
2-Aminosulfonyl-benzoic acid methyl ester
A benzoate ester that is methyl benzoate substituted by a sulfamoyl group at position 2. It is a metabolite of the herbicide metsulfuron-methyl.
2-Amino-2-deoxyglucose (hydrochloride)
2-Amino-2-deoxyglucose hydrochloride is a hexosamine hydrochloride can be used in the synthesis of cyclopropene-modified hexosamine derivative Ac4GlcNCyoc and Ac4GalNCyoc[1].