Exact Mass: 182.1095444
Exact Mass Matches: 182.1095444
Found 500 metabolites which its exact mass value is equals to given mass value 182.1095444,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Harman
Harman is an indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A. It has a role as an anti-HIV agent, a plant metabolite and an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is an indole alkaloid, an indole alkaloid fundamental parent and a harmala alkaloid.
Harman is a natural product found in Ophiopogon, Strychnos johnsonii, and other organisms with data available.
An indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A.
Isolated from roots of Panax ginseng and Codonopsis lanceolata (todok). Struct. has now been shown to be identical with 1-Acetyl-b-carboline
Dacarbazine
Dacarbazine appears as white to ivory microcrystals or off-white crystalline solid. (NTP, 1992) (E)-dacarbazine is a dacarbazine in which the N=N double bond adopts a trans-configuration. An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma. Dacarbazine is an Alkylating Drug. The mechanism of action of dacarbazine is as an Alkylating Activity. Dacarbazine (also known as DTIC) is an intravenously administered alkylating agent used in the therapy of Hodgkin disease and malignant melanoma. Dacarbazine therapy has been associated with serum enzyme elevations during therapy and occasional cases of severe and distinctive acute hepatic failure, probably caused by acute sinusoidal obstruction syndrome. Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04) An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564) Dacarbazine is only found in individuals that have used or taken this drug. It is an antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by its action as a purine analog, and interaction with SH groups. Dacarbazine is not cell cycle-phase specific. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents
(-)-2-Difluoromethylornithine
P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01C - Agents against leishmaniasis and trypanosomiasis C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D004791 - Enzyme Inhibitors > D065108 - Ornithine Decarboxylase Inhibitors C471 - Enzyme Inhibitor > C2088 - Ornithine Decarboxylase Inhibitor D000970 - Antineoplastic Agents D - Dermatologicals KEIO_ID H097
iridotrial
(R)-Methylphosphonofluoridic acid 1,2,2-trimethylpropyl ester
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents D004791 - Enzyme Inhibitors
Dihydroconiferyl alcohol
Dihydroconiferyl alcohol, also known as 3-(4-guaiacyl)propanol or 3-(4-hydroxy-3-methoxyphenyl)-propan-1-ol, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Dihydroconiferyl alcohol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Dihydroconiferyl alcohol can be found in lettuce and romaine lettuce, which makes dihydroconiferyl alcohol a potential biomarker for the consumption of these food products. Dihydroconiferyl alcohol is a cell division factor that can be found in pring sap of Acer pseudoplatanus L. Dihydroconiferyl alcohol can stimulate growth of soybean callus[1].
Neryl formate
Food flavouring. Neryl formate is found in lime, lemon, and sweet orange. Neryl formate is found in lemon. Neryl formate is a food flavouring.
1,2,3-Trimethoxy-5-methylbenzene
1,2,3-trimethoxy-5-methylbenzene is a member of the class of compounds known as anisoles. Anisoles are organic compounds containing a methoxybenzene or a derivative thereof. 1,2,3-trimethoxy-5-methylbenzene is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 1,2,3-trimethoxy-5-methylbenzene can be found in safflower and tea, which makes 1,2,3-trimethoxy-5-methylbenzene a potential biomarker for the consumption of these food products.
5,10-dihydrophenazine
A member of the class of phenazines obtained by hydrogenation of the 5 and 10 positions of phenazine.
[(R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetic acid
Carcinine
A beta-alanine derivative that is the amide obtained by formal condensation of the carboxy group of beta-alanine with the primary amino group of histamine.
(±)-threo-Anethole glycol
(±)-threo-Anethole glycol is found in fruits. (±)-threo-Anethole glycol is a constituent of Illicium verum (Chinese star anise). Constituent of Illicium verum (Chinese star anise). (±)-threo-Anethole glycol is found in fruits.
Linalyl formate
Linalyl formate is found in fruits. Linalyl formate is found in oils of lavender, peach, apricot, lime, clary and petitgrain. Linalyl formate is present in Prunus species. Linalyl formate is used in perfumery and food flavourin Linalyl formate is used in perfumery and food flavouring. It is found in oils of lavender, peach, apricot, lime, clary and petitgrain.
Methyl geranate
Methyl_geranate belongs to the family of Acyclic Monoterpenes. These are monoterpenes (compounds made of two consecutive isoprene units) that do not contain a cycle.
xi-2-Hexyl-5-methyl-3(2H)-furanone
xi-2-Hexyl-5-methyl-3(2H)-furanone is found in onion-family vegetables. xi-2-Hexyl-5-methyl-3(2H)-furanone is a constituent of onions, leeks and shallots.
4-Ethyl-2,6-dimethoxyphenol
4-Ethyl-2,6-dimethoxyphenol is a component of smoked food flavourings. Component of smoked food flavourings
Methyl (2E,4Z)-decadienoate
Methyl (2E,4Z)-decadienoate is found in fruits. Methyl (2E,4Z)-decadienoate is found in pears and spineless monkey orange. Flavour for candies et Found in pears and spineless monkey orange. Flavour for candies etc
4-(Ethoxymethyl)-2-methoxyphenol
4-(Ethoxymethyl)-2-methoxyphenol is a food additive listed in the EAFUS food Additive Database (Jan 2001). Food additive listed in the EAFUS Food Additive Database (Jan 2001)
Bornyl formate
Isobornyl formate is a flavouring agent. Flavouring agent
Methyl 4,8-decadienoate
Methyl 4,8-decadienoate is found in alcoholic beverages. Methyl 4,8-decadienoate is a constituent of essential oil of hops (Humulus lupulus) Constituent of essential oil of hops (Humulus lupulus). Methyl 4,8-decadienoate is found in alcoholic beverages and fats and oils.
Verimol J
Verimol J is found in fruits. Verimol J is a constituent of Illicium verum (Chinese star anise). Constituent of Illicium verum (Chinese star anise). Verimol J is found in fruits.
2,2,7,7-Tetramethyl-1,6-dioxaspiro[4.4]non-3-ene
2,2,7,7-Tetramethyl-1,6-dioxaspiro[4.4]non-3-ene is found in alcoholic beverages. 2,2,7,7-Tetramethyl-1,6-dioxaspiro[4.4]non-3-ene is a constituent of hops
Tsibulin 2
Phytoalexin from Allium cepa bulbs (onion) infected with Botrytis cinerea. Tsibulin 2 is found in garden onion and onion-family vegetables. Tsibulin 2 is found in onion-family vegetables. Phytoalexin from Allium cepa bulbs (onion) infected with Botrytis cinerea.
Peperinic acid
Peperinic acid is found in herbs and spices. Peperinic acid is isolated from aged peppermint oil. Isolated from aged peppermint oil. Peperinic acid is found in herbs and spices.
alpha-Terpineol formate
alpha-Terpineol formate is found in cardamom. alpha-Terpineol formate is a flavouring agent Flavouring agent. alpha-Terpinyl formate is found in cardamom and sweet bay.
5-Pentyl-3h-furan-2-one
5-Pentyl-3h-furan-2-one is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")
4-Hydroxy-4-methyl-7-decenoic acid gamma-lactone
4-Hydroxy-4-methyl-7-decenoic acid gamma-lactone is a flavouring agent for baked goods, candies and meat product Flavouring agent for baked goods, candies and meat products [DFC]
Ethyl octynecarboxylate
Ethyl octynecarboxylate is a flavouring ingredient. Flavouring ingredient
Furfuryl pentanoate
Furfuryl pentanoate is a flavouring ingredient. Flavouring ingredient
6-(3-Hexenyl)tetrahydro-2H-pyran-2-one
6-(3-Hexenyl)tetrahydro-2H-pyran-2-one is a flavouring ingredient. Flavouring ingredient
(3E,6Z)-Nonadien-1-yl acetate
(3E,6Z)-Nonadien-1-yl acetate is a food flavour.
(2E,6Z)-2,6-Nonadien-1-Yl acetate
(2E,6Z)-2,6-Nonadien-1-Yl acetate is a flavouring ingredient. Flavouring ingredient
cis-3-Hexenyl tiglate
cis-3-Hexenyl tiglate is a flavouring ingredient. Flavouring ingredient
2-Ethoxy-4-(methoxymethyl)phenol
2-Ethoxy-4-(methoxymethyl)phenol is a fragrance ingredient with a vanilla odour. Fragrance ingredient with a vanilla odour
Furfuryl isovalerate
Furfuryl isovalerate is found in coffee and coffee products. Furfuryl isovalerate is a flavouring ingredient. Furfuryl isovalerate is a constituent of coffee aroma. Flavouring ingredient. Constituent of coffee aroma. Furfuryl isovalerate is found in coffee and coffee products.
Allyl cyclohexylacetate
Allyl cyclohexylacetate is a flavouring ingredient. Flavouring ingredient
Isoamyl 2-furoate
Isoamyl 2-furoate belongs to the family of Furoic Acid Derivatives. These are organic compounds containing a furoic acid moiety, whose structure is characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.
4-Azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxazolidine]-5'-one
5,6-Dihydro-1,10-phenanthroline
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D007364 - Intercalating Agents D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
(S)-3-(2-Methylphenoxy)propane-1,2-diol
M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents Mephenesin is an NMDA receptor antagonist and Mephenesin is a central muscle relaxant.
(±)-erythro-Anethole glycol
Constituent of Illicium verum (Chinese star anise). (±)-erythro-Anethole glycol is found in fruits.
n-(hexahydro-1h-1,6-epoxypyrrolizin-7-yl)-n-methylformamide
xi-2-Hexyl-5-methyl-3(2H)-furanone
Xi-2-hexyl-5-methyl-3(2h)-furanone is a member of the class of compounds known as furanones. Furanones are compounds containing a furan ring bearing a ketone group. Xi-2-hexyl-5-methyl-3(2h)-furanone is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Xi-2-hexyl-5-methyl-3(2h)-furanone can be found in onion-family vegetables, which makes xi-2-hexyl-5-methyl-3(2h)-furanone a potential biomarker for the consumption of this food product. xi-2-Hexyl-5-methyl-3(2H)-furanone is found in onion-family vegetables. xi-2-Hexyl-5-methyl-3(2H)-furanone is a constituent of onions, leeks and shallots.
1,7-Dimethyl-3-oxo-norbornan-7-carbonsaeure|1,7-dimethyl-3-oxo-norbornane-7-carboxylic acid
(+-)-5-Oxo-2-isopropyl-cyclohexen-(6)-carbonsaeure-(1)|2-Isopropyl-cyclohexen-(6)-on-(5)-carbonsaeure-(1)|2-Methoaethyl-cyclohexen-(6)-on-(5)-carbonsaeure-(1)|5-oxo-o-menth-6-en-7-oic acid|5-Oxo-o-menth-6-en-7-saeure
3-[(2E)-4-hydroxy-4-methylpent-2-en-1-yl]furan-2(5H)-one|sibiscolactone
(3R,5S,7S,8S,9S)-3,8-epoxy-7-hydroxy-Delta4,11-dihyronepetane|jatamanin C
5,10-dihydro-benzo[b][1,7]naphthyridine|beta-Carbolin|Harman
3-(1-hydroxybutyl)-2,4-dimethylcyclopent-2-enone|phomotenone
4-(2-hydroxypropan-2-yl)cyclohexa-1,3-diene-1-carboxylic acid
methyl 5-isopropyl-2-methylcyclopentenecarboxylate
(3S,8S)-(-)-4,6-decadiyne-1,3,8-triol|4,6-decadiyne-1,3,8-triol|4,6-Decadiyne-1,3,8-triol-(3S,8S)-form
Dec-9-insaeure-methylester|dec-9-ynoic acid methyl ester|methyl 9-decynoate|Methyl dec-9-ynoate|methyl decinoate|methyl-9-decynoate
(5R,9R)-3,9-epoxy-10-hydroxy-Delta4,11,7,8dihyronepeta-1-ol|jatamanin K
(1R,4R)-4-methoxy-3,3,5-trimethyl-2-oxabicyclo[2.2.2]oct-5-ene
4-hydroxy-6-pentylpyran-2-one
A pyranone that is 2H-pyran-2-one in which the hydrogens at positions 4 and 6 are substituted by hydroxy and pentyl groups respectively.
guaiacyl propanol
Dihydroconiferyl alcohol is a member of class of phenols that is 2-methoxyphenol substituted by a 3-hydroxypropyl group at position 4. It has a role as a plant metabolite. It is a primary alcohol and a eugenol. Dihydroconiferyl alcohol is a natural product found in Euterpe oleracea, Broussonetia papyrifera, and other organisms with data available. See also: Acai fruit pulp (part of). A member of class of phenols that is 2-methoxyphenol substituted by a 3-hydroxypropyl group at position 4. Dihydroconiferyl alcohol is a cell division factor that can be found in pring sap of Acer pseudoplatanus L. Dihydroconiferyl alcohol can stimulate growth of soybean callus[1].
Harman
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.504 D009676 - Noxae > D009498 - Neurotoxins D009676 - Noxae > D009153 - Mutagens relative retention time with respect to 9-anthracene Carboxylic Acid is 0.500 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.495 IPB_RECORD: 461; CONFIDENCE confident structure Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect[1][2][3][4]. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect[1][2][3][4]. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect[1][2][3][4].
Harmane
Annotation level-1 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2281; CONFIDENCE confident structure IPB_RECORD: 2961; CONFIDENCE confident structure
Mephenesin
M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents Mephenesin is an NMDA receptor antagonist and Mephenesin is a central muscle relaxant.
(+/-)-cis-6-Hydroxy-1-Methylbicyclo[4.3.0]nonane-2,7-dione
1-(1-tert-butyl-4-hydroxy-1H-pyrazol-3-yl)ethanone
2,4(1H,3H)-Pyrimidinedione,6-methyl-3-(1-methylpropyl)-
Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, methyl ester
1-(TERT-BUTYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
4-AMINO-6-(TERT-BUTYL)-1-METHYL-1,2-DIHYDRO-1,3,5-TRIAZIN-2-ONE
4-ACETAMINO-4?-NITRODIPHENYLSULFONE-2?-SULFONAMIDE
3-Oxabicyclo[3.2.1]octane-2,4-dione,1,8,8-trimethyl-, (1R,5S)-
N-CYANO-N-[(TETRAHYDROFURAN-2-YL)METHYL]-N-METHYLGUANIDINE
1-METHYL-3-(2-METHYLPROPYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID
1-(tert-Butyl)-3-methyl-1H-pyrazole-5-carboxylic acid
1-ethyl-3-methyl-1h-pyrazole-5-carboxylic acid ethyl ester
(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxylic acid
5-ETHOXYCARBONYL-1H-HEXAHYDROPYRROLO[3,4-B]PYRROLE
3-(3,5-Dimethyl-pyrazol-1-yl)-2-methyl-propionic acid
methyl 2,6-dimethyl-4-oxocyclohex-2-ene-1-carboxylate
2-Furancarboxylic acid,5-(1,1-dimethylethyl)-, methyl ester
3-Furancarboxylic acid, 5-ethyl-2-methyl-, ethyl ester
1-(3-METHYLBUTYL)-1H-PYRAZOLE-4-BORONIC ACID
C8H15BN2O2 (182.12265200000002)
4-(3,5-dimethyl-1H-pyrazol-1-yl)butanoic acid(SALTDATA: FREE)
Bicyclo[2.2.1]heptane-1-carboxylic acid, 7,7-dimethyl-2-oxo-, (1R，4S)-
Mildronate
Meldonium (MET-88) dihydrate functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2). Mildronate dihydrate exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium dihydrate is a fatty acid oxidation inhibitor[1][2].
5-(4-methylpiperazin-1-yl)-1H-1,2,4-triazol-3-amine
1H-Pyrazole-3-carboxylicacid,5-ethyl-1-methyl-,ethylester(9CI)
3,3a,4,5,7,7a-Hexahydro-4,4,7a-trimethyl-6(2H)-benzofuranone
3,5-dimethyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylic acid
1-methyl-5-(2-methylpropyl)pyrazole-3-carboxylic acid
4,5,6,7,8,9-hexahydrocycloocta[d][1,3]thiazol-2-amine
7,7-DIMETHYL-2-OXOBICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID
2-Cyclohexylcyclopropanecarboxylic acid methyl ester
5-(1-methylpiperidin-4-yl)-1,3,4-oxadiazol-2-amine
4-Cyano-2,2,5,5-tetramethyl-3-imidazoline-3-oxide-1-oxyl
(4-ethyl-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid(SALTDATA: FREE)
2-(3,4,5-trimethyl-1H-pyrazol-1-yl)acetohydrazide(SALTDATA: FREE)
1,3-Cyclohexanedione,2-(diaminomethylene)-5,5-dimethyl-(9CI)
Propylene oxide adduct of phenol, formaldehyde polymer
MELAMINE, N(sup 2),N(sup 2),N(sup 4),N(sup 4)-TETRAMETHYL-
Bjerkanderol A
Isolated from Foeniculum vulgare (fennel). erythro-Anethole glycol is found in herbs and spices and anise.
1H-Indene-1,5(4H)-dione, hexahydro-3a-hydroxy-7a-methyl-
Methyl geranate
Methyl geranate, also known as methyl geranic acid or methyl (2e)-3,7-dimethylocta-2,6-dienoate, is a member of the class of compounds known as acyclic monoterpenoids. Acyclic monoterpenoids are monoterpenes that do not contain a cycle. Methyl geranate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Methyl geranate can be found in caraway, which makes methyl geranate a potential biomarker for the consumption of this food product. Methyl geranate exists in all eukaryotes, ranging from yeast to humans. Methyl_geranate belongs to the family of Acyclic Monoterpenes. These are monoterpenes (compounds made of two consecutive isoprene units) that do not contain a cycle.
(±)-erythro-Anethole glycol
Constituent of Illicium verum (Chinese star anise). (¬±)-erythro-Anethole glycol is found in fruits. Constituent of Illicium verum (Chinese star anise). (±)-erythro-Anethole glycol is found in fruits.
8-Hydroxy-3-methyl-3,4,4a,5,6,7-hexahydro-1H-2-benzopyran-1-one
7-Deoxyloganetic aldehyde
A cyclopentapyran that is (4aS,7aR)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran substituted at position 1 by a hydroxy group and at positions 4 and 7 by a formyl and methyl group, respectively (the 1R,4aS,7S,7aR-diastereomer).
[(2R,3R,4S,5R)-1,3,4,5,6-pentahydroxyhexan-2-yl]azanium
5-[(E)-dimethylaminodiazenyl]-1H-imidazole-2-carboxamide
isobornyl formate
A bornane monoterpenoid that is isoborneol in which the hydroxy hydrogen has been replaced by a formyl group.
2,6,6-Trimethyl-3-ethylcarbonyl-5,6-dihydro-4H-pyran
6-(3-Methyl-2-butenyloxy)-4-methyl-5,6-dihydro-2H-pyran
Dacarbazine
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents Dacarbazine appears as white to ivory microcrystals or off-white crystalline solid. (NTP, 1992) (E)-dacarbazine is a dacarbazine in which the N=N double bond adopts a trans-configuration. An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma. Dacarbazine is an Alkylating Drug. The mechanism of action of dacarbazine is as an Alkylating Activity. Dacarbazine (also known as DTIC) is an intravenously administered alkylating agent used in the therapy of Hodgkin disease and malignant melanoma. Dacarbazine therapy has been associated with serum enzyme elevations during therapy and occasional cases of severe and distinctive acute hepatic failure, probably caused by acute sinusoidal obstruction syndrome. Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04) An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564) C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
SOMAN
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents D004791 - Enzyme Inhibitors
EFLORNITHINE
P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01C - Agents against leishmaniasis and trypanosomiasis C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D004791 - Enzyme Inhibitors > D065108 - Ornithine Decarboxylase Inhibitors C471 - Enzyme Inhibitor > C2088 - Ornithine Decarboxylase Inhibitor D000970 - Antineoplastic Agents D - Dermatologicals