Carcinine (BioDeep_00000017018)

   


代谢物信息卡片


Carcinine hydrochloride salt

化学式: C8H14N4O (182.1167554)
中文名称: 麦角三氟乙酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(NC=N1)CCNC(=O)CCN
InChI: InChI=1S/C8H14N4O/c9-3-1-8(13)11-4-2-7-5-10-6-12-7/h5-6H,1-4,9H2,(H,10,12)(H,11,13)

描述信息

A beta-alanine derivative that is the amide obtained by formal condensation of the carboxy group of beta-alanine with the primary amino group of histamine.

同义名列表

2 个代谢物同义名

Carcinine; Carcinine hydrochloride salt



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark A Babizhayev, Anatoliy I Deyev, Ekaterina L Savel'yeva, Vadim Z Lankin, Yegor E Yegorov. Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and skin aging. The Journal of dermatological treatment. 2012 Oct; 23(5):345-84. doi: 10.3109/09546634.2010.521812. [PMID: 21756141]
  • Lea D Marchette, Huaiwen Wang, Feng Li, Mark A Babizhayev, Anne Kasus-Jacobi. Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina. Investigative ophthalmology & visual science. 2012 Jun; 53(7):3572-83. doi: 10.1167/iovs.11-9042. [PMID: 22577078]
  • Mark A Babizhayev. Designation of imidazole-containing dipeptides as pharmacological chaperones. Human & experimental toxicology. 2011 Jul; 30(7):736-61. doi: 10.1177/0960327110377526. [PMID: 20656726]
  • Mark A Babizhayev, Yegor E Yegorov. Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of advanced glycation end products. Critical reviews in therapeutic drug carrier systems. 2010; 27(2):85-154. doi: 10.1615/critrevtherdrugcarriersyst.v27.i2.10. [PMID: 20486899]
  • Brendan A Gavin, Susan E Arruda, Patrick J Dolph. The role of carcinine in signaling at the Drosophila photoreceptor synapse. PLoS genetics. 2007 Dec; 3(12):e206. doi: 10.1371/journal.pgen.0030206. [PMID: 18069895]
  • Mark A Babizhayev. Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products. Life sciences. 2006 Apr; 78(20):2343-57. doi: 10.1016/j.lfs.2005.09.054. [PMID: 16388826]
  • M A Babizhayev, M C Seguin, J Gueyne, R P Evstigneeva, E A Ageyeva, G A Zheltukhina. L-carnosine (beta-alanyl-L-histidine) and carcinine (beta-alanylhistamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase activities. The Biochemical journal. 1994 Dec; 304 ( Pt 2)(?):509-16. doi: 10.1042/bj3040509. [PMID: 7998987]
  • R P Evstigneeva, G A Zheltukhina, E A Ageeva, M A Babizhaev. [Lipoperoxidase activity of carnosine and carcinine]. Doklady Akademii nauk. 1993 Nov; 333(1):104-6. doi: ". [PMID: 8298483]
  • L Flancbaum, D N Brotman, J C Fitzpatrick, T Van Es, E Kasziba, H Fisher. Existence of carcinine, a histamine-related compound, in mammalian tissues. Life sciences. 1990; 47(17):1587-93. doi: 10.1016/0024-3205(90)90188-w. [PMID: 2250571]
  • M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study. Cancer treatment reports. 1979 Sep; 63(9-10):1663-7. doi: . [PMID: 91435]
  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]