Exact Mass: 149.0786
Exact Mass Matches: 149.0786
Found 261 metabolites which its exact mass value is equals to given mass value 149.0786,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
6-Methyladenine
6-Methyladenine is a methylated adenine residue. The formation of internal 6-methyladenine (m6A) residues in eucaryotic messenger RNA (mRNA) is a postsynthetic modification in which S-adenosyl-L-methionine (SAM) serves as the methyl donor. 6-Methyladenine residues have also been localized to heterogeneous nuclear RNA (HnRNA), and for the most part these residues are conserved during mRNA processing. Although the biological significance of internal adenine methylation in eucaryotic mRNA remains unclear, a great deal of research has indicated that this modification may be required for mRNA transport to the cytoplasm, the selection of splice sites or other RNA processing reactions. The presence of m6A residues increases the in vitro translation efficiency of dihydrofolate reductase; an inhibition of m6A residues in dihydrofolate reductase transcripts significantly alters their rate of translation. m6A is found in many human fluids: oviductal fluid, blood plasma and urine. (PMID: 1551452, 8925412, 10481270, 16083005, 16684535, 3506820, 3728186) [HMDB] 6-Methyladenine is a methylated adenine residue. The formation of internal 6-methyladenine (m6A) residues in eucaryotic messenger RNA (mRNA) is a postsynthetic modification in which S-adenosyl-L-methionine (SAM) serves as the methyl donor. 6-Methyladenine residues have also been localized to heterogeneous nuclear RNA (HnRNA), and for the most part these residues are conserved during mRNA processing. Although the biological significance of internal adenine methylation in eucaryotic mRNA remains unclear, a great deal of research has indicated that this modification may be required for mRNA transport to the cytoplasm, the selection of splice sites or other RNA processing reactions. The presence of m6A residues increases the in vitro translation efficiency of dihydrofolate reductase; an inhibition of m6A residues in dihydrofolate reductase transcripts significantly alters their rate of translation. m6A is found in many human fluids: oviductal fluid, blood plasma and urine (PMID:1551452, 8925412, 10481270, 16083005, 16684535, 3506820, 3728186). D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D006133 - Growth Substances > D010937 - Plant Growth Regulators KEIO_ID M072
cathinone
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant The S stereoisomer of 2-aminopropiophenone.
1-Methyladenine
1-Methyladenine is the product of reaction between 1-methyladenosine and water which is catalyzed by 1-methyladenosine nucleosidase (EC:3.2.2.13). 1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation, a reaction requiring ferrous iron and 2-oxoglutarate as cofactor and co-substrate, respectively (PMID:15576352). 1-Methyladenine is found to be associated with adenosine deaminase (ADA) deficiency, which is an inborn error of metabolism. 1-Methyladenine is the product of reaction between 1-methyladenosine and water which is catalyzed by 1-methyladenosine nucleosidase. (EC:3.2.2.13) KEIO_ID M074
3-Methyladenine
3-Methyladenine, also known as 3-ma nucleobase, belongs to the class of organic compounds known as 6-aminopurines. These are purines that carry an amino group at position 6. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring. 3-Methyladenine exists in all living species, ranging from bacteria to humans. 3-Methyladenine has been detected, but not quantified, in several different foods, such as soft-necked garlics, chinese bayberries, burbots, amaranths, and tea. This could make 3-methyladenine a potential biomarker for the consumption of these foods. 3-Methyladenine is one of the purines damaged by alkylation and oxidation which can be recognized and excised by the human 3-methyladenine DNA glycosylase (AAG) (EC: EC3.2.2.21). 3-Methyladenine is one of the purines damaged by alkylation and oxidation which can be recognized and excised by the human 3-methyladenine DNA glycosylase (AAG) (EC: EC 3.2.2.21) [HMDB]. 3-Methyladenine is found in many foods, some of which are sacred lotus, evergreen huckleberry, swamp cabbage, and red rice. Acquisition and generation of the data is financially supported in part by CREST/JST. KEIO_ID M030
7-Methyladenine
7-Methyladenine is part of the base excision repair pathway. In this pathway, alkylated DNA is hydrolysed via the enzyme DNA-3-methyladenine glycosylase II (EC 3.2.2.21), releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. This enzyme is responsible for the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. Base excision repair (BER) is a cellular mechanism that repairs damaged DNA throughout the cell cycle. Repairing DNA sequence errors is necessary so that mutations are not propagated or to remove lesions that may lead to breaks in the DNA during replication. Single bases in DNA can be chemically mutated, for example by deamination or alkylation, resulting in incorrect base-pairing, and consequently, mutations in the DNA. Base excision repair involves flipping the mutated base out of the DNA helix and repairing the base alone. There are two main enzymes used, DNA glycosylases and AP endonucleases. The DNA glycosylase is used to break the beta-N glycosidic bond to create an AP site. AP endonuclease recognizes this site and nicks the damaged DNA on the 5 side (upstream) of the AP site creating a free 3-OH. DNA polymerase, Pol I (human pol beta), extends the DNA from the free 3-OH using its exonuclease activity to replace the nucleotide of the damaged base, as well as a few downstream, followed by sealing of the new DNA strand by DNA ligase. In mammalian cells, this is done by LigIII in complex with the scaffold protein XRCC1. Usually, BER is divided into short-patch repair (where a single nucleotide is replaced) or long-patch repair (where 2-10 nucleotides are replaced). Mammalian long-patch repair includes PCNA and pol delta/epsilon for nucleotide resynthesis, FEN1 to cut of the flap including the damaged base, and LigI. 7-Methyladenine is part of the base excision repair pathway. In this pathway, alkylated DNA is hydrolysed via the enzyme DNA-3-methyladenine glycosylase II (EC 3.2.2.21), releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. This enzyme is responsible for the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. (Pathway Commons)
N,N-dihydroxy-L-valine
An N,N-dihydroxy amino acid that is derived from L-valine.
4-Aminopropiophenone
D020011 - Protective Agents > D011837 - Radiation-Protective Agents
Venoterpine
Venoterpine is found in alcoholic beverages. Venoterpine is an alkaloid from Gentiana lutea (yellow gentian
2,3,6,7-Tetrahydrocyclopent[b]azepin-8(1H)-one
Proline-specific Maillard product. Proline-specific Maillard product
2-(2-Furanyl)-3,4,5,6-tetrahydropyridine
Proline-derived Maillard product. Proline-derived Maillard product
2,3-Dihydro-5-methyl-1H-pyrrolizine-7-carboxaldehyde
Proline-derived Maillard product. Proline-derived Maillard product
3-(2-Furanylmethylene)pyrrolidine
Putative proline-derived Maillard product formed in model reactions with proline or 1-pyrroline and ascorbic acid. Putative proline-derived Maillard product formed in model reactions with proline or 1-pyrroline and ascorbic acid
2,3-Dihydro-6-methyl-1H-pyrrolizine-5-carboxaldehyde
2,3-Dihydro-6-methyl-1H-pyrrolizine-5-carboxaldehyde is found in alcoholic beverages. Proline-derived Maillard product. 2,3-Dihydro-6-methyl-1H-pyrrolizine-5-carboxaldehyde is a volatile constituent of beer and cooked asparagus. Proline-derived Maillard product. Volatile constituent of beer and cooked asparagus. 2,3-Dihydro-6-methyl-1H-pyrrolizine-5-carboxaldehyde is found in alcoholic beverages and green vegetables.
3,4-Dihydro-5-(5-methyl-2-furanyl)-2H-pyrrole
Putative proline-derived Maillard product formed in model reactions with 1-pyrroline and ascorbic acid. Putative proline-derived Maillard product formed in model reactions with 1-pyrroline and ascorbic acid
5-Acetyl-2,3-dihydro-1H-pyrrolizine
Proline-derived Maillard product. Constituent of popcorn, beer and cooked asparagus aroma. 5-Acetyl-2,3-dihydro-1H-pyrrolizine is found in alcoholic beverages, cereals and cereal products, and green vegetables. 5-Acetyl-2,3-dihydro-1H-pyrrolizine is found in alcoholic beverages. Proline-derived Maillard product. 5-Acetyl-2,3-dihydro-1H-pyrrolizine is a constituent of popcorn, beer and cooked asparagus aroma.
2-Aminopropiophenone
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs
4-(Dimethylamino)benzaldehyde
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
N-(2,4-Dimethylphenyl)formamide
CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6854; ORIGINAL_PRECURSOR_SCAN_NO 6851 CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7772; ORIGINAL_PRECURSOR_SCAN_NO 7771 CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7817; ORIGINAL_PRECURSOR_SCAN_NO 7816 CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7824; ORIGINAL_PRECURSOR_SCAN_NO 7822 CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6922; ORIGINAL_PRECURSOR_SCAN_NO 6920 CONFIDENCE standard compound; INTERNAL_ID 890; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7827; ORIGINAL_PRECURSOR_SCAN_NO 7824 CONFIDENCE standard compound; EAWAG_UCHEM_ID 330
2-Amino-2-deoxyxylose|alpha-D-2-Amino-2-deoxyxylose
2,4-dimethylphenylformamid
CONFIDENCE standard compound; INTERNAL_ID 3830
3-methyladenine
A methyladenine that is adenine substituted with a methyl group at position N-3.
p-Dimethylaminobenzaldehyde
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7759; ORIGINAL_PRECURSOR_SCAN_NO 7757 CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7778; ORIGINAL_PRECURSOR_SCAN_NO 7775 CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7806; ORIGINAL_PRECURSOR_SCAN_NO 7803 CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7816; ORIGINAL_PRECURSOR_SCAN_NO 7814 CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7800; ORIGINAL_PRECURSOR_SCAN_NO 7798 CONFIDENCE standard compound; INTERNAL_ID 873; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7820; ORIGINAL_PRECURSOR_SCAN_NO 7815 INTERNAL_ID 873; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7820; ORIGINAL_PRECURSOR_SCAN_NO 7815
3-Methyl-3,4-dihydro-2H-1,4-benzoxazine
CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7759; ORIGINAL_PRECURSOR_SCAN_NO 7757 CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7778; ORIGINAL_PRECURSOR_SCAN_NO 7775 CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7806; ORIGINAL_PRECURSOR_SCAN_NO 7803 CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7816; ORIGINAL_PRECURSOR_SCAN_NO 7814 CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7800; ORIGINAL_PRECURSOR_SCAN_NO 7798 CONFIDENCE standard compound; INTERNAL_ID 1186; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7820; ORIGINAL_PRECURSOR_SCAN_NO 7815
2-Aminopropiophenone
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs
Pyrimido[5,4-e]-1,2,4-triazine, 1,2-dihydro-3-methyl- (9CI)
Pyrido[4,3-e]-1,2,4-triazin-3-amine, 1,2-dihydro- (9CI)
1,2,7-triazabicyclo[4.3.0]nona-2,4,6,8-tetraen-3-ylhydrazine
3,5,7,9-tetrazabicyclo[4.4.0]deca-2,4,6,8-tetraen-4-amine
1H-Imidazole-4,5-dicarbonitrile,2-amino-4,5-dihydro-1-methyl-(9CI)
1H-Imidazo[4,5-d]pyridazin-4-amine,7-methyl- (9CI)
Pyrimido[5,4-e]-1,2,4-triazine,1,2-dihydro-1-methyl-
1H-Pyrazolo[4,3-d]pyrimidin-7-amine,3-methyl- (9CI)
4-METHYL-1,5,6,7-TETRAHYDRO-2H-CYCLOPENTA[B]-PYRIDIN-2-ONE
1H-Indole-2-carboxaldehyde, 4,5,6,7-tetrahydro- (9CI)
6-Methyladenine
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents A methyladenine that is 9H-purin-6-amine substituted by a methyl group at the amino nitrogen. D006133 - Growth Substances > D010937 - Plant Growth Regulators
6-methyl-2,3-dihydro-1H-pyrrolizine-5-carbaldehyde
2,3-Dihydro-5-methyl-1H-pyrrolizine-7-carboxaldehyde
D-Lyxosylamine
A hexosamine that is D-lyxopyranose in which the anomeric hydroxy group has been replaced by an amino group
