Classification Term: 78

Tetrahydropyridines (ontology term: CHEMONTID:0001934)

Derivatives of pyridine in which two double bonds in the pyridine moiety are reduced by adding four hydrogen atoms." []

found 30 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Hydropyridines

Child Taxonomies: 1,2,3,6-Tetrahydropyridines

1-Piperideine-2-carboxylic acid

3,4,5,6-Tetrahydro-2-pyridinecarboxylic acid

C6H9NO2 (127.0633254)


1-Piperideine-2-carboxylic acid (P2C), also known as Δ1-pipecolic acid, is classified as a member of the tetrahydropyridines. Tetrahydropyridines are derivatives of pyridine in which two double bonds in the pyridine moiety are reduced by adding four hydrogen atoms. 1-Piperideine-2-carboxylic acid is considered to be slightly soluble (in water) and acidic. 1-Piperideine-2-carboxylic acid is an intermediate of the L-lysine metabolic pathway in the brain; the uptake of P2C into the synaptosome of the cerebral cortex was Na+ and temperature-dependent (PMID: 7654748). delta 1-Piperidine-2-carboxylic acid (P2C), an intermediate of the L-lysine metabolic pathway in the brain; the uptake of P2C into the synaptosome of the cerebral cortex was Na+ and temperature-dependent (PMID 7654748 ) [HMDB]

   

Glutarimide

Glutarimide calcium salt

C5H7NO2 (113.0476762)


D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors

   

Anabaseine

3-(3,4,5,6-tetrahydropyridin-2-yl)pyridine

C10H12N2 (160.1000432)


D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes[1][2]. Anabaseine is also a weak partial agonist at α4β2 nAChRs[3].

   

Gymnodimine

5-[(2E)-19-hydroxy-2,15,18,24-tetramethyl-25-oxa-7-azatetracyclo[20.2.1.0⁶,¹¹.0¹¹,¹⁶]pentacosa-2,6,14,17-tetraen-14-yl]-3-methyl-2,5-dihydrofuran-2-one

C32H45NO4 (507.33484100000004)


Gymnodimine is found in mollusks. Gymnodimine is isolated from New Zealand oysters (Tiostrea chilensis) and the dinoflagellate Gymnodinium cf. mikimotoi. Isolated from New Zealand oysters (Tiostrea chilensis) and the dinoflagellate Gymnodinium cf. mikimotoi. Gymnodimine is found in mollusks.

   

2,4-Undecadiene-8,10-diynoic acid 2,3-dehydropiperidide

(2E,4Z)-1-(1,2,3,4-tetrahydropyridin-1-yl)undeca-2,4-dien-8,10-diyn-1-one

C16H17NO (239.1310072)


2,4-Undecadiene-8,10-diynoic acid 2,3-dehydropiperidide is found in herbs and spices. 2,4-Undecadiene-8,10-diynoic acid 2,3-dehydropiperidide is isolated from Achillea millefolium (yarrow). Isolated from Achillea millefolium (yarrow). 2,4-Undecadiene-8,10-diynoic acid 2,3-dehydropiperidide is found in herbs and spices.

   

Pandamarilactone 31

6-methoxy-6-methyl-1-{4-[(2E)-4-methyl-5-oxo-2,5-dihydrofuran-2-ylidene]butyl}-1H,2H,3H,4H,5H,6H,7H-cyclopenta[b]pyridin-5-one

C19H25NO4 (331.178349)


Pandamarilactone 31 is a food flavouring. Pandamarilactone 31 is an alkaloid from leaves of Pandanus amaryllifolius. Food flavouring. Alkaloid from leaves of Pandanus amaryllifolius

   

(2E,4E,6Z)-2,4,6-Decatrienoic acid dehydropiperidide

(2E,4Z,6E)-1-(1,2,3,4-tetrahydropyridin-1-yl)deca-2,4,6-trien-1-one

C15H21NO (231.1623056)


(2E,4E,6Z)-2,4,6-Decatrienoic acid dehydropiperidide is found in herbs and spices. (2E,4E,6Z)-2,4,6-Decatrienoic acid dehydropiperidide is an alkaloid from Achillea millefolium (yarrow). Alkaloid from Achillea millefolium (yarrow). (2E,4E,6Z)-2,4,6-Decatrienoic acid dehydropiperidide is found in herbs and spices.

   

2-(1-Propenyl)-delta1-piperideine

2-[(1Z)-prop-1-en-1-yl]-3,4,5,6-tetrahydropyridine

C8H13N (123.1047938)


2-(1-Propenyl)-delta1-piperideine is found in fruits. 2-(1-Propenyl)-delta1-piperideine is isolated from pomegranate (leaves). Isolated from pomegranate (leaves). 2-(1-Propenyl)-delta1-piperideine is found in fruits.

   

2,4,6,8-Decatetraenoic acid dehydropiperidide

(2E,4Z,6E,8E)-1-(1,2,3,4-tetrahydropyridin-1-yl)deca-2,4,6,8-tetraen-1-one

C15H19NO (229.14665639999998)


2,4,6,8-Decatetraenoic acid dehydropiperidide is found in herbs and spices. 2,4,6,8-Decatetraenoic acid dehydropiperidide is an alkaloid from Achillea millefolium (yarrow). Alkaloid from Achillea millefolium (yarrow). 2,4,6,8-Decatetraenoic acid dehydropiperidide is found in herbs and spices.

   

Nepetalactam

4,7-dimethyl-1H,2H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyridin-1-one

C10H15NO (165.115358)


Nepetalactam is found in herbs and spices. Nepetalactam is isolated from a commercial sample of catnip oil (Nepeta cataria). Isolated from a commercial sample of catnip oil (Nepeta cataria). Nepetalactam is found in tea and herbs and spices.

   

Pandamarilactone 32

1-{4-[(2E)-4-methyl-5-oxo-2,5-dihydrofuran-2-ylidene]butyl}-6-methylidene-1H,2H,3H,4H,5H,6H,7H-cyclopenta[b]pyridin-5-one

C18H21NO3 (299.1521356)


Pandamarilactone 32 is a food flavouring. Pandamarilactone 32 is a major alkaloid from leaves of Pandanus amaryllifolius. Food flavouring. Major alkaloid from leaves of Pandanus amaryllifolius

   

6-Acetyl-1,2,3,4-tetrahydropyridine

Methyl 3,4,5,6-tetrahydro-2-pyridyl ketone, 8ci

C7H11NO (125.0840596)


6-Acetyl-1,2,3,4-tetrahydropyridine is found in cereals and cereal products. Responsible for mousy taint in wines. 6-Acetyl-1,2,3,4-tetrahydropyridine is a constituent of wheat, popcorn and bread aroma 6-Acetyl-2,3,4,5-tetrahydropyridine is a substituted tetrahydropyridine and a cyclic imine as well as a ketone. The compound exists in a chemical equilibrium with its tautomer 6-acetyl-1,2,3,4-tetrahydropyridine that differs only by the position of the double bond in the tetrahydropyridine ring:; 6-Acetyl-2,3,4,5-tetrahydropyridine, with the IUPAC name 1-(3,4,5,6-tetrahydropyridin-2-yl)ethanone, is an aroma compound and flavor that gives baked goods such as white bread, pop corn, or tortillas their typical smell, together with its structural homolog 2-acetyl-1-pyrroline

   

(E)-5-(3,4,5,6-Tetrahydro-3-pyridylidenemethyl)-2-furanmethanol

{5-[(3Z)-3,4,5,6-tetrahydropyridin-3-ylidenemethyl]furan-2-yl}methanol

C11H13NO2 (191.09462380000002)


(E)-5-(3,4,5,6-Tetrahydro-3-pyridylidenemethyl)-2-furanmethanol is produced of reaction between glucose and lysine in slightly acid solution. Production of reacn. between glucose and lysine in sl. acid soln.

   

1,2,3,4-Tetrahydro-6-propanoylpyridine

1-(1,4,5,6-tetrahydro-2-Pyridinyl)-1-propanone, 9ci

C8H13NO (139.0997088)


1,2,3,4-Tetrahydro-6-propanoylpyridine is formed by thermal treatment of proline and glucose mixture Formed by thermal treatment of proline and glucose mixtures

   

6-Acetyl-2,3-dihydro-2-(hydroxymethyl)-4(1H)-pyridinone

6-acetyl-2-(hydroxymethyl)-1,2,3,4-tetrahydropyridin-4-one

C8H11NO3 (169.0738896)


6-Acetyl-2,3-dihydro-2-(hydroxymethyl)-4(1H)-pyridinone is a minor product from the Maillard reaction of xylose and glycin Minor product from the Maillard reaction of xylose and glycine

   

1,2,3,4,5,6-Hexahydro-5-(1-hydroxyethylidene)-7H-cyclopenta[b]pyridin-7-one

(5E)-5-(1-hydroxyethylidene)-1H,2H,3H,4H,5H,6H,7H-cyclopenta[b]pyridin-7-one

C10H13NO2 (179.09462380000002)


Proline-derived Maillard product. Proline-derived Maillard product

   

5-(2-Furanyl)-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

5-(2-Furanyl)-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

C12H13NO2 (203.09462380000002)


Proline-derived Maillard product. Proline-derived Maillard product

   

1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one

1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one

C8H11NO (137.0840596)


1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one is found in alcoholic beverages. Proline-derived Maillard product. 1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one is a constituent of wort and beer. 1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one is a flavouring ingredient. Proline-derived Maillard product. Constituent of wort and beer. Flavouring ingredient. 1,2,3,4,5,6-Hexahydro-7H-cyclopenta[b]pyridin-7-one is found in alcoholic beverages.

   

1,2,3,4,5,6-Hexahydro-5-methyl-7H-cyclopenta[b]pyridin-7-one

1,2,3,4,5,6-Hexahydro-5-methyl-7H-cyclopenta[b]pyridin-7-one

C9H13NO (151.0997088)


Proline-derived Maillard product. Proline-derived Maillard product

   

1,2,3,4,5,6-Hexahydro-6-methyl-7H-cyclopenta[b]pyridin-7-one

1,2,3,4,5,6-Hexahydro-6-methyl-7H-cyclopenta[b]pyridin-7-one

C9H13NO (151.0997088)


Proline-derived Maillard product. Proline-derived Maillard product

   

5-Ethyl-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

5-Ethyl-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

C10H15NO (165.115358)


Proline-derived Maillard product. Proline-derived Maillard product

   

6-Ethyl-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

6-Ethyl-1,2,3,4,5,6-hexahydro-7H-cyclopenta[b]pyridin-7-one

C10H15NO (165.115358)


Proline-derived Maillard product. Proline-derived Maillard product

   

2,3,4,5-Tetrahydro-6-(5-methyl-2-furanyl)pyridine

6-(5-methylfuran-2-yl)-2,3,4,5-tetrahydropyridine

C10H13NO (163.0997088)


Proline-derived Maillard product. Proline-derived Maillard product

   

2-(2-Furanyl)-3,4,5,6-tetrahydropyridine

6-(furan-2-yl)-2,3,4,5-tetrahydropyridine

C9H11NO (149.0840596)


Proline-derived Maillard product. Proline-derived Maillard product

   

2-Acetyl-3-ethylidene-3,4,5,6-tetrahydropyridine

1-[(3Z)-3-ethylidene-3,4,5,6-tetrahydropyridin-2-yl]ethan-1-one

C9H13NO (151.0997088)


Proline or lysine-derived Maillard product. Proline or lysine-derived Maillard product

   

Tetrahydropyridine

1,2,3,4-tetrahydropyridine

C5H9N (83.0734954)


   

2,4(1H,3H)-Pyridinedione

1,2,3,4-tetrahydropyridine-2,4-dione

C5H5NO2 (111.032027)


   

PIPERIDIN-2-IMINE

Piperidin-(2E)-ylideneamine

C5H10N2 (98.084394)


   

2-(2'-Propenyl)-delta-1-piperideine

2-(prop-2-en-1-yl)-3,4,5,6-tetrahydropyridine

C8H13N (123.1047938)


2-(2-propenyl)-delta-1-piperideine is a member of the class of compounds known as tetrahydropyridines. Tetrahydropyridines are derivatives of pyridine in which two double bonds in the pyridine moiety are reduced by adding four hydrogen atoms. 2-(2-propenyl)-delta-1-piperideine is practically insoluble (in water) and a very strong basic compound (based on its pKa). 2-(2-propenyl)-delta-1-piperideine can be found in pomegranate, which makes 2-(2-propenyl)-delta-1-piperideine a potential biomarker for the consumption of this food product.

   

2-acetyl-1,4,5,6-tetrahydropyridine

2-acetyl-1,4,5,6-tetrahydropyridine,2-acetyl-1,4,5,6-tetrahydropyridine,1-(1,4,5,6-tetrahydro-2-pyridinyl)-ethanone

C7H11NO (125.0840596)


Flavouring compound [Flavornet]