Classification Term: 170605
Kavalactones and derivatives (ontology term: 762d32123de623c5cd707d763790f9f3)
found 63 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Styrylpyrones
Child Taxonomies: There is no child term of current ontology term.
Yangonin
Yangonin is a member of 2-pyranones and an aromatic ether. Yangonin is a natural product found in Piper methysticum, Ranunculus silerifolius, and Piper majusculum with data available. See also: Piper methysticum root (part of). Yangonin is found in beverages. Yangonin is found in kava root (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002). Found in kava root (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002) Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively. Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively.
Marindinin
Marindinin is found in beverages. Marindinin is found in the roots of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002 Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks. Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.
Desmethoxyyangonin
Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B. Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
Dihydrokavain
Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks. Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.
Methysticin
Methysticin is a member of 2-pyranones and an aromatic ether. Methysticin is a natural product found in Piper methysticum and Piper majusculum with data available. See also: Piper methysticum root (part of). Methylsticin is a kavalactone isolated from the Piper methysticum . Methylsticin exhibit osteoclast formation inhibitory activity[1]. Methylsticin is a kavalactone isolated from the Piper methysticum . Methylsticin exhibit osteoclast formation inhibitory activity[1].
6-(2-chloro-1-hydroxy-2-phenylethyl)-5,6-dihydropyran-2-one
(2r,3s,4r,6r)-3-(acetyloxy)-6-{[(2r)-6-oxo-2,3-dihydropyran-2-yl]methyl}-2-[(1e)-2-phenylethenyl]oxan-4-yl acetate
[(2r,3s,4s,5r,6s)-6-({2-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]-6-oxopyran-4-yl}oxy)-3,4,5-trihydroxyoxan-2-yl]methyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate
3-[2-(3,4-dihydroxyphenyl)ethenyl]-8,9-dihydroxypyrano[4,3-c]isochromene-1,6-dione
6-[2-(2h-1,3-benzodioxol-5-yl)ethyl]-4-methoxypyran-2-one
4-methoxy-6-[2-(6-methoxy-2h-1,3-benzodioxol-5-yl)ethenyl]pyran-2-one
4-methoxy-3-methyl-6-[(1e)-2-phenylethenyl]pyran-2-one
(6r)-6-(4-oxo-6-phenylhex-2-en-1-yl)-5,6-dihydropyran-2-one
3-[2-(2-{6-[2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2-oxopyran-3-yl}-4,5-dihydroxyphenyl)ethenyl]-8,9-dihydroxypyrano[4,3-c]isochromene-1,6-dione
4-hydroxy-6-(4-hydroxyphenyl)-5,6-dihydropyran-2-one
(6r)-6-[(2r,3r)-3-phenyloxiran-2-yl]-5,6-dihydropyran-2-one
(1e,3s,4r)-1-[(2s,3r,3ar,7ar)-3-hydroxy-5-oxo-2h,3h,3ah,7ah-furo[3,2-b]pyran-2-yl]-4-hydroxypent-1-en-3-yl benzoate
{2-hydroxy-5-oxo-10-phenyl-4-oxatricyclo[4.3.1.0³,⁷]dec-8-en-1-yl}methyl benzoate
(6r)-6-[(1r,2r)-2-chloro-1-hydroxy-2-phenylethyl]-5,6-dihydropyran-2-one
(2s)-5-hydroxy-7-[(1s,2s)-2-hydroxy-2-[(2s)-6-oxo-2,3-dihydropyran-2-yl]-1-phenylethoxy]-2-phenyl-2,3-dihydro-1-benzopyran-4-one
(6r)-6-[(1e,4r,6r,7e)-4,6-dihydroxy-8-phenylocta-1,7-dien-1-yl]-5,6-dihydropyran-2-one
6-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]pyran-2-one
8-hydroxy-3-(2-phenylethenyl)-3,4-dihydro-2-benzopyran-1-one
2,4-dimethoxy-6-oxo-2-(2-phenylethenyl)-3h-pyran-3-yl acetate
6-oxo-2-(3-phenyloxiran-2-yl)-2,3-dihydropyran-3-yl acetate
(1r,6s,7s,8s)-7-(4-hydroxyphenyl)-1-[(1e)-2-(4-hydroxyphenyl)ethenyl]-4-methoxy-8-(4-methoxy-6-oxopyran-2-yl)-2-oxabicyclo[4.2.0]oct-4-en-3-one
4-methoxy-6-[(1e)-2-(4-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)ethenyl]pyran-2-one
(6r)-6-[(2r,4r,5e)-2,4-dihydroxy-6-phenylhex-5-en-1-yl]-5,6-dihydropyran-2-one
(1r,2s)-2-(acetyloxy)-2-[(2r)-6-oxo-2,3-dihydropyran-2-yl]-1-phenylethyl acetate
(6r)-6-[(2s,3r)-3-phenyloxiran-2-yl]-5,6-dihydropyran-2-one
(6r)-6-{[(2s,4s,5s,6r)-4,5-dihydroxy-6-[(1e)-2-phenylethenyl]oxan-2-yl]methyl}-5,6-dihydropyran-2-one
{3-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]-8,9-dihydroxy-1-oxo-6h-pyrano[4,3-c]isochromen-6-yl}acetic acid
4-hydroxy-3-[(1r,6r)-6-isopropyl-3-methylcyclohex-2-en-1-yl]-6-[(1e)-2-phenylethenyl]pyran-2-one
5-hydroxy-8-(6-oxo-2,3-dihydropyran-2-yl)-1-phenylocta-1,7-dien-3-yl acetate
6-[2-(3,4-dihydroxyphenyl)-6-[2-(3,4-dihydroxyphenyl)ethenyl]-4-oxo-2h,3h-furo[3,2-c]pyran-3-yl]-4-hydroxypyran-2-one
6-(2,4-dihydroxy-6-phenylhex-5-en-1-yl)-5,6-dihydropyran-2-one
5-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]-11,12-dihydroxy-4,8-dioxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5,10,12-pentaen-3-one
6-(2-hydroxy-4-phenylbut-3-en-1-yl)-5,6-dihydropyran-2-one
methyl 3-(3,4-dihydroxyphenyl)-2-{6-[2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2-oxopyran-3-yl}prop-2-enoate
3-{4,5-dihydroxy-2-[(1e)-2-(4-hydroxy-6-oxopyran-2-yl)ethenyl]phenyl}-6-[(1e)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxypyran-2-one
6-[2-(3,4-dihydroxyphenyl)ethenyl]-3-(1-{6-[2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-2-oxopyran-3-yl}-3-methylbutyl)-4-hydroxypyran-2-one
(2s,3e)-1-[(2s)-6-oxo-2,3-dihydropyran-2-yl]-4-phenylbut-3-en-2-yl acetate
7-(2-phenylethenyl)-2,6-dioxabicyclo[3.3.1]nonan-3-one
(6r)-8,9-dihydroxy-3-[(1e)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-6-methoxy-6h-pyrano[4,3-c]isochromen-1-one
4-hydroxy-6-[(1e)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}pyran-2-one
C20H22O11 (438.11620619999997)