Classification Term: 168236
Diacylglycerophosphoethanolamines [GP0201] (ontology term: e3064f16da11d3293e33794f90d895dc)
Diacylglycerophosphoethanolamines [GP0201]
found 155 associated metabolites at sub_class
metabolite taxonomy ontology rank level.
Ancestor: Glycerophosphoethanolamines [GP02]
Child Taxonomies: There is no child term of current ontology term.
PE(16:0/18:1(9Z))
PE(16:0/18:1(9Z)) is a phosphatidylethanolamine (PE or GPEtn). It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, glycerophosphoethanolamines can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. PE(16:0/18:1(9Z)), in particular, consists of one chain of palmitic acid at the C-1 position and one chain of oleic acid at the C-2 position. The palmitic acid moiety is derived from fish oils, milk fats, vegetable oils and animal fats, while the oleic acid moiety is derived from vegetable oils, especially olive and canola oil. Phospholipids, are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling.While most phospholipids have a saturated fatty acid on C-1 and an unsaturated fatty acid on C-2 of the glycerol backbone, the fatty acid distribution at the C-1 and C-2 positions of glycerol within phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. PEs are neutral zwitterions at physiological pH. They mostly have palmitic or stearic acid on carbon 1 and a long chain unsaturated fatty acid (e.g. 18:2, 20:4 and 22:6) on carbon 2. PE synthesis can occur via two pathways. The first requires that ethanolamine be activated by phosphorylation and then coupled to CDP. The ethanolamine is then transferred from CDP-ethanolamine to phosphatidic acid to yield PE. The second involves the decarboxylation of PS. PE(16:0/18:1(9Z)) is a phosphatidylethanolamine. It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, glycerophosphoethanolamines can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 atoms. PE(16:0/18:1(9Z)), in particular, consists of one hexadecanoyl chain to the C-1 atom, and one 9Z-octadecenoyl to the C-2 atom. While most phospholipids have a saturated fatty acid on C-1 and an unsaturated fatty acid on C-2 of the glycerol backbone, the fatty acid distribution at the C-1 and C-2 positions of glycerol within phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. PEs are neutral zwitterions at physiological pH. They mostly have palmitic or stearic acid on carbon 1 and a long chain unsaturated fatty acid (e.g. 18:2, 20:4 and 22:6) on carbon 2. PE synthesis can occur via two pathways. The first requires that ethanolamine be activated by phosphorylation and then coupled to CDP. The ethanolamine is then transferred from CDP-ethanolamine to phosphatidic acid to yield PE. The second involves the decarboxylation of PS.
PE 38:4
C43H78NO8P (767.5464757999999)
Found in mouse spleen; TwoDicalId=400; MgfFile=160729_spleen_EPA_09_Neg; MgfId=1087 Found in mouse brain; TwoDicalId=840; MgfFile=160720_brain_normal_01_Neg; MgfId=1007 Found in mouse kidney; TwoDicalId=2; MgfFile=160827_Kidney_EPA_Neg_10; MgfId=1506 Found in mouse small intestine; TwoDicalId=515; MgfFile=160907_Small_Intestine_AA_Neg_17; MgfId=1532 Found in mouse spleen; TwoDicalId=110; MgfFile=160729_spleen_AA_17_Neg; MgfId=1218
PE 35:2
Found in mouse small intestine; TwoDicalId=682; MgfFile=160907_Small_Intestine_EPA_Neg_08; MgfId=1314
PE 37:4
Found in mouse kidney; TwoDicalId=330; MgfFile=160827_Kidney_normal_Neg_01_sute; MgfId=1352
PE 37:5
Found in mouse kidney; TwoDicalId=684; MgfFile=160827_Kidney_AA_Neg_20; MgfId=1185
PE 39:7
Found in mouse heart; TwoDicalId=690; MgfFile=160902_Heart_Control_Neg_01_sute; MgfId=803
PE 38:3
Found in mouse small intestine; TwoDicalId=186; MgfFile=160907_Small_Intestine_EPA_Neg_08; MgfId=1574
PE 40:4
Found in mouse kidney; TwoDicalId=1308; MgfFile=160827_Kidney_DHA_Neg_12_never; MgfId=1720 Found in mouse spleen; TwoDicalId=71; MgfFile=160729_spleen_AA_20_Neg; MgfId=1529
PE 42:4
Found in mouse spleen; TwoDicalId=1045; MgfFile=160729_spleen_AA_16_Neg; MgfId=1610
PE 42:2
Found in mouse lung; TwoDicalId=758; MgfFile=160901_Lung_normal_Neg_04; MgfId=1584
PE 39:4
Found in mouse kidney; TwoDicalId=452; MgfFile=160827_Kidney_EPA_Neg_09; MgfId=1694
PE 42:9
Found in mouse heart; TwoDicalId=877; MgfFile=160902_Heart_Control_Neg_01_sute; MgfId=816
PE 44:10
C49H78NO8P (839.5464757999999)
Found in mouse muscle; TwoDicalId=113; MgfFile=160824_Muscle_AA_Neg_19; MgfId=814
PE 34:4
Found in mouse lung; TwoDicalId=633; MgfFile=160901_Lung_AA_Neg_17; MgfId=741
PE 37:6
Found in mouse muscle; TwoDicalId=711; MgfFile=160824_Muscle_EPA_Neg_07_never; MgfId=730
PE 32:0
Found in mouse spleen; TwoDicalId=317; MgfFile=160729_spleen_AA_16_Neg; MgfId=1135
PE 32:1
Found in mouse lung; TwoDicalId=178; MgfFile=160901_Lung_normal_Neg_03; MgfId=741
PE 34:0
C39H78NO8P (719.5464757999999)
Found in mouse brain; TwoDicalId=365; MgfFile=160720_brain_AA_18_Neg; MgfId=1568
PE 34:1
Found in mouse brain; TwoDicalId=80; MgfFile=160720_brain_AA_18_Neg; MgfId=1248
PE 34:2
Found in mouse brain; TwoDicalId=387; MgfFile=160720_brain_DHA_14_Neg; MgfId=934 Found in mouse liver; TwoDicalId=32; MgfFile=160824_Liver_EPA_Neg_10; MgfId=688
PE 34:3
Found in mouse liver; TwoDicalId=184; MgfFile=160824_Liver_EPA_Neg_10; MgfId=537 Found in mouse liver; TwoDicalId=432; MgfFile=160824_Liver_EPA_Neg_07; MgfId=541
PE 36:4
Found in mouse kidney; TwoDicalId=158; MgfFile=160827_Kidney_DHA_Neg_12_never; MgfId=1026 Found in mouse kidney; TwoDicalId=13; MgfFile=160827_Kidney_EPA_Neg_09; MgfId=1204
PE 36:5
Found in mouse brain; TwoDicalId=246; MgfFile=160720_brain_AA_18_Neg; MgfId=834 Found in mouse kidney; TwoDicalId=41; MgfFile=160827_Kidney_AA_Neg_18; MgfId=1100
PE 38:5
Found in mouse spleen; TwoDicalId=38; MgfFile=160729_spleen_EPA_07_Neg; MgfId=1066 Found in mouse kidney; TwoDicalId=17; MgfFile=160827_Kidney_normal_Neg_02_never; MgfId=1185 Found in mouse liver; TwoDicalId=21; MgfFile=160824_Liver_EPA_Neg_10; MgfId=782 Found in mouse kidney; TwoDicalId=16; MgfFile=160827_Kidney_AA_Neg_18; MgfId=1365 Found in mouse muscle; TwoDicalId=50; MgfFile=160824_Muscle_EPA_Neg_07; MgfId=778 Found in mouse muscle; TwoDicalId=134; MgfFile=160824_Muscle_AA_Neg_19; MgfId=942
PE 38:6
Found in mouse liver; TwoDicalId=42; MgfFile=160824_Liver_EPA_Neg_07_never; MgfId=694 Found in mouse kidney; TwoDicalId=12; MgfFile=160827_Kidney_DHA_Neg_15; MgfId=1194
PE 36:6
Found in mouse kidney; TwoDicalId=496; MgfFile=160827_Kidney_AA_Neg_18; MgfId=926
PE 38:7
Found in mouse muscle; TwoDicalId=136; MgfFile=160824_Muscle_normal_Neg_01_sute; MgfId=709
PE 39:6
Found in mouse heart; TwoDicalId=135; MgfFile=160902_Heart_DHA_Neg_12_never; MgfId=1030
PE 36:1
Found in mouse brain; TwoDicalId=72; MgfFile=160720_brain_AA_18_Neg; MgfId=1626
PE 36:2
C41H78NO8P (743.5464757999999)
Found in mouse brain; TwoDicalId=84; MgfFile=160720_brain_normal_01_Neg; MgfId=1120 Found in mouse small intestine; TwoDicalId=36; MgfFile=160907_Small_Intestine_EPA_Neg_08; MgfId=1470
PE 38:1
Found in mouse brain; TwoDicalId=703; MgfFile=160720_brain_EPA_08_Neg; MgfId=1958
PE 38:2
Found in mouse brain; TwoDicalId=277; MgfFile=160720_brain_AA_19_Neg; MgfId=1636 Found in mouse spleen; TwoDicalId=1513; MgfFile=160729_spleen_DHA_14_Neg; MgfId=1425
PE 40:5
Found in mouse liver; TwoDicalId=97; MgfFile=160824_Liver_EPA_Neg_10; MgfId=916 Found in mouse spleen; TwoDicalId=48; MgfFile=160729_spleen_EPA_07_Neg; MgfId=1335
PE 40:6
C45H78NO8P (791.5464757999999)
Found in mouse spleen; TwoDicalId=128; MgfFile=160729_spleen_EPA_07_Neg_never; MgfId=1117 Found in mouse kidney; TwoDicalId=307; MgfFile=160827_Kidney_normal_Neg_03; MgfId=1351 Found in mouse brain; TwoDicalId=6; MgfFile=160720_brain_AA_20_Neg; MgfId=1260
PE 36:3
Found in mouse kidney; TwoDicalId=75; MgfFile=160827_Kidney_DHA_Neg_11; MgfId=1231
PE 40:7
Found in mouse heart; TwoDicalId=194; MgfFile=160902_Heart_EPA_Neg_06; MgfId=760 Found in mouse heart; TwoDicalId=15; MgfFile=160902_Heart_Control_Neg_01_sute; MgfId=875
PE 40:8
Found in mouse kidney; TwoDicalId=92; MgfFile=160827_Kidney_DHA_Neg_15; MgfId=1080 Found in mouse heart; TwoDicalId=22; MgfFile=160902_Heart_DHA_Neg_12_never; MgfId=823
PE 40:9
Found in mouse muscle; TwoDicalId=408; MgfFile=160824_Muscle_DHA_Neg_14; MgfId=618
PE 41:6
Found in mouse heart; TwoDicalId=277; MgfFile=160902_Heart_DHA_Neg_12; MgfId=1249
PE 42:7
Found in mouse heart; TwoDicalId=274; MgfFile=160902_Heart_DHA_Neg_14; MgfId=1042
PE 42:10
Found in mouse heart; TwoDicalId=246; MgfFile=160902_Heart_AA_Neg_20; MgfId=722
PE 42:11
Found in mouse muscle; TwoDicalId=167; MgfFile=160824_Muscle_normal_Neg_03; MgfId=492
PE 28:0
PE 52:4
PE 26:0
PE 37:0
PE 38:0
PE 42:0
C47H94NO8P (831.6716693999999)
PE 44:12
PE 36:0
PE 24:0
PE 16:0
C21H42NO8P (467.26479020000005)
PE 30:0
PE 32:2
PE 40:2
PE 40:0
PE 40:1
PE 44:0
PE 35:0
PE 42:1
PE 44:1
C49H96NO8P (857.6873185999999)
PE 46:1
PE-NMe2 24:0
PE-NMe2 28:0
PE-NMe2 36:0
PE-NMe2 40:0
C47H94NO8P (831.6716693999999)
PE-NMe2 34:1
PE-NMe2 32:0
C39H78NO8P (719.5464757999999)
PE-NMe2 36:2
PE-NMe 36:2
PE-NMe 32:0
PE-NMe 34:1
C40H78NO8P (731.5464757999999)
PE-NMe 24:0
PE-NMe 28:0
PE-NMe 36:0
PE-NMe 40:0
PE-NMe 22:0
NAPE 34:2
C57H108NO9P (981.7761287999999)
PE 35:1
C40H78NO8P (731.5464757999999)
PE 35:6
PE 36:7
PE 37:3
C42H78NO8P (755.5464757999999)
PE 37:7
PE 39:5
C44H78NO8P (779.5464757999999)
PE 39:8
PE 38:8
PE 38:9
PE 40:10
PE 41:7
C46H78NO8P (803.5464757999999)
PE 42:8
C47H78NO8P (815.5464757999999)
PE 43:1
C48H94NO8P (843.6716693999999)
PE 44:2
C49H94NO8P (855.6716693999999)
PE 44:8
NAPE 34:1
C59H106NO9P (1003.7604795999999)