Classification Term: 167900
二氢黄酮醇 (ontology term: ed623353b7e153dcac78890a45bfbdc5)
二氢黄酮醇
found 163 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: 黄酮类
Child Taxonomies: There is no child term of current ontology term.
trans-3,3',4',5,5',7-Hexahydroxyflavanone
(+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin. Dihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus). Dihydromyricetin is a naturally occurring flavonoid found in the many plant species and is thought to be the active ingredient of several traditional Japanese, Chinese, and Korean medicines that are used to treat fever, parasite infections, liver diseases, and hangovers. Dihydromyricetin preparations have not been linked to instances of serum enzyme elevations or clinically apparent liver injury with jaundice. Dihydromyricetin is a natural product found in Vitis rotundifolia, Catha edulis, and other organisms with data available. (±)-trans-3,3,4,5,5,7-Hexahydroxyflavanone is found in tea. (±)-trans-3,3,4,5,5,7-Hexahydroxyflavanone is a constituent of Camellia sinensis (Chinese green tea). Constituent of Camellia sinensis (Chinese green tea). (±)-Dihydromyricetin is found in tea. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM.
Aromadendrin
(+)-dihydrokaempferol is a tetrahydroxyflavanone having hydroxy groupa at the 3-, 4-, 5- and 7-positions. It has a role as a metabolite. It is a tetrahydroxyflavanone, a member of dihydroflavonols, a secondary alpha-hydroxy ketone and a member of 4-hydroxyflavanones. It is functionally related to a kaempferol. It is a conjugate acid of a (+)-dihydrokaempferol 7-oxoanion. Aromadendrin is a natural product found in Smilax corbularia, Ventilago leiocarpa, and other organisms with data available. See also: Acai fruit pulp (part of). Isolated from Citrus subspecies and many other plants. Aromadendrin is found in many foods, some of which are thistle, coriander, adzuki bean, and almond. Aromadendrin is found in citrus. Aromadendrin is isolated from Citrus species and many other plant A tetrahydroxyflavanone having hydroxy groupa at the 3-, 4-, 5- and 7-positions. Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents[1]. Dihydrokaempferol. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=480-20-6 (retrieved 2024-09-18) (CAS RN: 480-20-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Isosilybin
Constituent of Silybum marianum (milk thistle). Isosilybin is found in coffee and coffee products and green vegetables. Isosilybin is found in coffee and coffee products. Isosilybin is a constituent of Silybum marianum (milk thistle) Isosilybin is a natural product found in Silybum with data available. [Raw Data] CBA83_Isosilybin-B_pos_20eV.txt [Raw Data] CBA83_Isosilybin-B_neg_30eV.txt [Raw Data] CBA83_Isosilybin-B_neg_20eV.txt [Raw Data] CBA83_Isosilybin-B_pos_10eV.txt [Raw Data] CBA83_Isosilybin-B_pos_40eV.txt [Raw Data] CBA83_Isosilybin-B_neg_10eV.txt [Raw Data] CBA83_Isosilybin-B_pos_50eV.txt [Raw Data] CBA83_Isosilybin-B_pos_30eV.txt [Raw Data] CBA83_Isosilybin-B_neg_50eV.txt [Raw Data] CBA83_Isosilybin-B_neg_40eV.txt Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM. Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum; inhibits CYP3A4 induction with an IC50 of 74 μM.
DTXSID901001957
3-Hydroxyglabrol
3-Hydroxyglabrol is found in herbs and spices. 3-Hydroxyglabrol is from Glycyrrhiza glabra (licorice
Dihydroprudomenin
C23H26O12 (494.14241960000004)
Dihydroprudomenin is found in fruits. Dihydroprudomenin is isolated from wood of Prunus mume (Japanese apricot). Isolated from wood of Prunus mume (Japanese apricot). Dihydroprudomenin is found in herbs and spices and fruits.
Dihydroisorhamnetin
Dihydroisorhamnetin is found in beverages. Dihydroisorhamnetin is isolated from Dillenia indica (elephant apple). Isolated from Dillenia indica (elephant apple). Dihydroisorhamnetin is found in beverages and fruits.
4',5,7-Trihydroxy-3-methoxyflavanone
4,5,7-Trihydroxy-3-methoxyflavanone is found in european plum. 4,5,7-Trihydroxy-3-methoxyflavanone is a constituent of Prunus domestica (plum). Constituent of Prunus domestica (plum). Aromadendrin 3-methyl ether is found in fruits and european plum.
Aromadendrin 4'-methyl ether 7-rhamnoside
C22H24O10 (448.13694039999996)
Aromadendrin 4-methyl ether 7-rhamnoside is found in citrus. Aromadendrin 4-methyl ether 7-rhamnoside is a constituent of the fruit of orange (Citrus sinensis). Constituent of the fruit of orange (Citrus sinensis). Aromadendrin 4-methyl ether 7-rhamnoside is found in sweet orange and citrus.
Isosilychristin
Constituent of Silybum marianum (milk thistle). Isosilychristin is found in coffee and coffee products and green vegetables. Isosilychristin is found in coffee and coffee products. Isosilychristin is a constituent of Silybum marianum (milk thistle).
3,5-Dihydroxy-6,7-methylenedioxyflavanone
3,5-Dihydroxy-6,7-methylenedioxyflavanone is found in common beet. 3,5-Dihydroxy-6,7-methylenedioxyflavanone is a constituent of sugarbeet infected with Rhizoctonia solani. Constituent of sugarbeet infected with Rhizoctonia solani. 3,5-Dihydroxy-6,7-methylenedioxyflavanone is found in common beet.
Pinobanksin 5-[galactosyl-(1->4)-glucoside]
Pinobanksin 5-[galactosyl-(1->4)-glucoside] is found in fruits. Pinobanksin 5-[galactosyl-(1->4)-glucoside] is isolated from the famine food Adansonia digitata (baobab). Isolated from the famine food Adansonia digitata (baobab). Pinobanksin 5-[galactosyl-(1->4)-glucoside] is found in fruits.
2',3,5-Trihydroxy-5',7-dimethoxyflavanone
2,3,5-Trihydroxy-5,7-dimethoxyflavanone is found in tea. 2,3,5-Trihydroxy-5,7-dimethoxyflavanone is isolated from Blumea balsamifera (sambong). Isolated from Blumea balsamifera (sambong). 2,3,5-Trihydroxy-5,7-dimethoxyflavanone is found in tea.
Hovenitin I
Hovenitin II is a constituent of the seeds and fruit of Hovenia dulcis (raisin tree). Constituent of the seeds and fruit of Hovenia dulcis (raisin tree).
Engeletin
Engeletin is a natural product found in Smilax corbularia, Malpighia emarginata, and other organisms with data available. Engeletin is a metabolite found in or produced by Saccharomyces cerevisiae. Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects. Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
Cedrin
Cedrin is a natural product found in Cedrus deodara with data available.
Padmatin
Padmatin is a natural product found in Chromolaena odorata, Dittrichia graveolens, and other organisms with data available.
Aromadendrin 6-C-glucoside
C21H22O11 (450.11620619999997)
3,5,7,4-Tetrahydroxy-3-(5-formyl-2-hydroxyphenyl)flavanone
Phellodendroside
Flavoplatycoside
Sanggenol H
An organic heterotetracyclic compound that is 5a,10a-dihydro-11H-[1]benzofuro[3,2-b]chromen-11-one substituted by hydroxy groups at positions 1, 3, 8 and 10a and a triprenyl group at position 5a. It has been isolated from Morus nigra.
3,5,7,3,4-Pentahydroxy-6-prenylflavanone 7-glucoside
Taxillusin
Petalostemumol
3,5,4-Trihydroxy-4,5-dihydro-6,6-dimethylpyrano[2,3:7,8]flavanone
7,8-Dihydrooxepinodihydroquercetin
3,5,7,2,5-Pentahydroxyflavanone 3-rhamnoside
C21H22O11 (450.11620619999997)
diplacol
Pinobanksin 5-methyl ether
Dihydrorobinetin
Dihydrorobinetin is a natural product found in Robinia pseudoacacia and Adenanthera pavonina Dihydrorobinetin is a naturally occurring organic compound, classified as a flavanonol, which is a type of flavonoid. It is the dihydro derivative of robinetin, meaning it has two additional hydrogen atoms compared to robinetin. The chemical formula of dihydrorobinetin is C15H14O6. This compound is found in various plants and has been studied for its potential biological activities, including antioxidant and anti-inflammatory properties. Dihydrorobinetin, like other flavonoids, is known for its ability to scavenge free radicals and modulate cellular processes, which may contribute to its health benefits. (+)-Dihydrorobinetin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=4382-33-6 (retrieved 2024-07-12) (CAS RN: 4382-33-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Shuterone A
Dihydrophelloside
5-Methoxypeltogynone
Aromadendrin 7-methyl ether 5-glucoside
C22H24O11 (464.13185539999995)
3,5,4-Trihydroxy-4,5,dihydro-5-isopropenylfurano[2,3:7,8]flavanone
Kushenol X
Sanggenon M
Sorocein F
3,5,7,4-Tetrahydroxy-8-(3-hydroxy-3-methylbutyl)flavanone
Aromadendrin 3-galactoside
C21H22O11 (450.11620619999997)
3,5,6-Trimethoxy-3,4-methylene-dioxyfurano[2,3:7,8]flavanone
Mopanone
Kushenol H
Lupinifolinol
Crombeone
Bonanniol A
Sanggenol I
Rel-5-hydroxy-7,4-dimethoxy-2S-(2,4,5-trimethoxy-E-styryl)-tetrahydrofuro[4R,5R:2,3]flavanonol
Dihydrorhamnetin 3-O-beta-D-arabinopyranoside
C21H22O11 (450.11620619999997)
3,5,4-Trihydroxy-6,6-dimethylpyrano[2,3:7,8]flavanone
Sorocein D
Aromadendrin 7,4-dimethyl ether 5-glucoside
C23H26O11 (478.14750460000005)
Shuterol
Phellavin
Lecontin
Keyakinol
C22H24O11 (464.13185539999995)
Mundulinol
5-Methoxymopanone
3,5,7,3,4-Pentahydroxy-6-methoxyflavanone 3-acetate
3-O-Methyllupinifolinol
Ampelopsin 3-methyl ether 4-rhamnoside
8-C-Glucosyldihydrokaempferol
C21H22O11 (450.11620619999997)
3,5,7,4-Tetrahydroxy-8-methoxyflavanone 3-angelate
Isoglucodistylin
Isoengeletin
Isoengeletin is a natural product found in Smilax corbularia and Iryanthera sagotiana with data available.
Aromadendrin 7-rhamnosyl- (1->4) -galactoside
Astilbin
C21H22O11 (450.11620619999997)
Neoisoastilbin is a natural product found in Smilax corbularia, Neolitsea sericea, and other organisms with data available. Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation. Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation. Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer’s disease research[1][21][3]. Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer’s disease research[1][21][3]. Neoisoastilbin possesses antioxidant, anti-hyperuricemic and anti-Inflammatory activities[1]. Neoisoastilbin possesses antioxidant, anti-hyperuricemic and anti-Inflammatory activities[1].
Dihydromorin
Dihydromorin is a natural product found in Broussonetia papyrifera, Artocarpus altilis, and other organisms with data available.
Myricatin
Kushenol I
Kushenol I is a natural compound isolated from the roots of Sophora flavescens[1]. Kushenol I is a natural compound isolated from the roots of Sophora flavescens[1].
Shuterin
Taxifolin
A pentahydroxyflavanone that is the 2,3-dihydro derivative of quercetin. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Origin: Plant; Formula(Parent): C15H12O7; Bottle Name:(+-)-Taxifolin; PRIME Parent Name:Dihydroquercetin; PRIME in-house No.:S0088, Pyrans relative retention time with respect to 9-anthracene Carboxylic Acid is 0.594 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.596 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.590 Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2]. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].