Miquelianin (BioDeep_00000230319)

Main id: BioDeep_00000398145

 

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(2S,3S,4S,5R,6S)-6-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

化学式: C21H18O13 (478.0747)
中文名称: 槲皮素-3-O-葡萄糖醛酸苷, 槲皮素-3-葡萄糖醛酸苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=CC2OC(C3C=C(O)C(O)=CC=3)=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(=O)O)O3)C(=O)C=2C(O)=C1
InChI: InChI=1S/C21H18O13/c22-7-4-10(25)12-11(5-7)32-17(6-1-2-8(23)9(24)3-6)18(13(12)26)33-21-16(29)14(27)15(28)19(34-21)20(30)31/h1-5,14-16,19,21-25,27-29H,(H,30,31)/t14-,15-,16+,19-,21+/m0/s1

描述信息

Miquelianin is a quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities. It has a role as a metabolite, an antioxidant and an antidepressant. It is a beta-D-glucosiduronic acid and a quercetin O-glycoside.
quercetin 3-O-glucuronide is a natural product found in Theobroma grandiflorum, Eucalyptus cypellocarpa, and other organisms with data available.
See also: Bilberry (part of); Theobroma grandiflorum seed (part of).
A quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities.
Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid.
Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid.

同义名列表

49 个代谢物同义名

(2S,3S,4S,5R,6S)-6-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; (2S,3S,4S,5R,6S)-6-(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yloxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; (2S,3S,4S,5R)-6-(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-2H-pyran-2-carboxylic acid; (2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-chromen-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid; (2S,3S,4S,5R,6S)-6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; GLUCOPYRANOSIDURONIC ACID, 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4-OXO-4H-1-BENZOPYRAN-3-YL, .BETA.-D-; .beta.-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl; GLUCOPYRANOSIDURONIC ACID, 2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4-OXO-4H-1-BENZOPYRAN-3-YL, beta-D-; beta-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(.beta.-D-glucopyranuronosyloxy)-5,7-dihydroxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl beta-D-glucopyranosiduronic acid; Quercetin 3-glucuronide, primary pharmaceutical reference standard; Quercetin 3-glucuronideQuercetin 3-O-glucuronide; Quercetin 3-glucuronide, >=95\\% (LC/MS-ELSD); Quercetin 3-glucuronide, analytical standard; 3,3,4,5,7-Pentahydroxyflavone 3-glucuronide; QUERCETIN 3-O-.BETA.-D-GLUCURONOPYRANOSIDE; quercetin-3-O-beta-D-glucuronopyranoside; QUERCETIN 3-O-beta-D-GLUCURONOPYRANOSIDE; QUERCETIN-3-O-.BETA.-D-GLUCURONIDE; quercetin 3-O-beta-glucopyranoside; Quercetin 3-O-.beta.-D-glucuronide; Quercetin-3-O-beta-D-glucuronide; quercetin 3-O-beta-D-glucuronide; QUERCETIN-3-.BETA.-D-GLUCURONIDE; Quercetin-3-glucosiduronic acid; Quercetein-3-O-beta-glucuronide; QUERCETIN 3-.BETA.-GLUCURONIDE; QUERCETIN-3-beta-D-GLUCURONIDE; Quercetin 3-O-|A-D-glucuronide; Quercetin 3-O-β-D-glucuronide; QUERCETIN 3-beta-GLUCURONIDE; QUERCETIN .BETA.-GLUCURONIDE; quercetin-3-O-glucoronoside; QUERCETIN beta-GLUCURONIDE; quercetin 3-O-glucuronide; QUERCETIN-3-O-GLUCURONIDE; quercetin-3-glucuronide; Quercetin 3-glucuronide; QUERCETIN GLUCURONIDE; UNII-RY36PD0CQ2; MEGxp0_000321; Querciturone; ACon1_000029; Quercituron; Miquelianin; Mikwelianin; RY36PD0CQ2; Quercetin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

373 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Zhenyu Wang, Tian Yang, Maomao Zeng, Zhaojun Wang, Qiuming Chen, Jie Chen, Mark Christian, Zhiyong He. Mitophagy suppression by miquelianin-rich lotus leaf extract induces 'beiging' of white fat via AMPK/DRP1-PINK1/PARKIN signaling axis. Journal of the science of food and agriculture. 2023 Nov; ?(?):. doi: 10.1002/jsfa.13143. [PMID: 37991930]
  • Zhenyu Wang, Tian Yang, Maomao Zeng, Zhaojun Wang, Qiuming Chen, Jie Chen, Mark Christian, Zhiyong He. Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Oct; 181(?):114089. doi: 10.1016/j.fct.2023.114089. [PMID: 37804915]
  • Muxin Zheng, Shenghao Chen, Yi Liu, Yang He. α-Glucosidase inhibitory activities of constituents from Psidium guajava leaves. Natural product research. 2023 Jul; ?(?):1-4. doi: 10.1080/14786419.2023.2238113. [PMID: 37506309]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Zhenyu Wang, Chaoyi Xue, Xuan Wang, Maomao Zeng, Zhaojun Wang, Qiuming Chen, Jie Chen, Mark Christian, Zhiyong He. Quercetin 3-O-glucuronide-rich lotus leaf extract promotes a Brown-fat-phenotype in C3H10T1/2 mesenchymal stem cells. Food research international (Ottawa, Ont.). 2023 01; 163(?):112198. doi: 10.1016/j.foodres.2022.112198. [PMID: 36596137]
  • Daniel Muñoz-Reyes, Alfredo G Casanova, Ana María González-Paramás, Ángel Martín, Celestino Santos-Buelga, Ana I Morales, Francisco J López-Hernández, Marta Prieto. Protective Effect of Quercetin 3-O-Glucuronide against Cisplatin Cytotoxicity in Renal Tubular Cells. Molecules (Basel, Switzerland). 2022 Feb; 27(4):. doi: 10.3390/molecules27041319. [PMID: 35209106]
  • Małgorzata Domżalska, Wiesław Wiczkowski, Aleksandra Szczepkowska, Sylwia Chojnowska, Tomasz Misztal, Fruzsina R Walter, Maria A Deli, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Janina Skipor. Effect of Lipopolysaccharide-Induced Inflammatory Challenge on β-Glucuronidase Activity and the Concentration of Quercetin and Its Metabolites in the Choroid Plexus, Blood Plasma and Cerebrospinal Fluid. International journal of molecular sciences. 2021 Jul; 22(13):. doi: 10.3390/ijms22137122. [PMID: 34281178]
  • Singeun Kim, Ki-Bae Hong, Kyungae Jo, Hyung Joo Suh. Quercetin-3-O-glucuronide in the Ethanol Extract of Lotus Leaf (Nelumbo nucifera) Enhances Sleep Quantity and Quality in a Rodent Model via a GABAergic Mechanism. Molecules (Basel, Switzerland). 2021 May; 26(10):. doi: 10.3390/molecules26103023. [PMID: 34069439]
  • Tae Heon Kim, Hyun Young Shin, Soon Yeong Park, Hoon Kim, Dae Kyun Chung. Development and Validation of a Method for Determining the Quercetin-3-O-glucuronide and Ellagic Acid Content of Common Evening Primrose (Oenothera biennis) by HPLC-UVD. Molecules (Basel, Switzerland). 2021 Jan; 26(2):. doi: 10.3390/molecules26020267. [PMID: 33430409]
  • Enkhtaivan Gansukh, Arti Nile, Doo Hwan Kim, Jae Wook Oh, Shivraj Hariram Nile. New insights into antiviral and cytotoxic potential of quercetin and its derivatives - A biochemical perspective. Food chemistry. 2021 Jan; 334(?):127508. doi: 10.1016/j.foodchem.2020.127508. [PMID: 32711265]
  • Kirsten Berger, Johanna Josefine Ostberg-Potthoff, Tamara Bakuradze, Peter Winterhalter, Elke Richling. Carbohydrate Hydrolase-Inhibitory Activity of Juice-Based Phenolic Extracts in Correlation to Their Anthocyanin/Copigment Profile. Molecules (Basel, Switzerland). 2020 Nov; 25(22):. doi: 10.3390/molecules25225224. [PMID: 33182561]
  • Sakina Bouderias, Péter Teszlák, Gábor Jakab, László Kőrösi. Age- and season-dependent pattern of flavonol glycosides in Cabernet Sauvignon grapevine leaves. Scientific reports. 2020 08; 10(1):14241. doi: 10.1038/s41598-020-70706-7. [PMID: 32859977]
  • Marí C Santos, Mariana Koetz, Andreas S L Mendez, Amélia T Henriques. Ultrasound-assisted extraction optimization and validation of ultra-performance liquid chromatographic method for the quantification of miquelianin in Cuphea glutinosa leaves. Talanta. 2020 Aug; 216(?):120988. doi: 10.1016/j.talanta.2020.120988. [PMID: 32456919]
  • Jeffrey P Davis, Mihoko Koyanagi, Robert R Maronpot, Leslie Recio, Shim-Mo Hayashi. Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague-Dawley rats. Archives of toxicology. 2020 07; 94(7):2413-2421. doi: 10.1007/s00204-020-02760-z. [PMID: 32388820]
  • Diahann J Perdicaro, Cecilia Rodriguez Lanzi, Julián Gambarte Tudela, Roberto M Miatello, Patricia I Oteiza, Marcela A Vazquez Prieto. Quercetin attenuates adipose hypertrophy, in part through activation of adipogenesis in rats fed a high-fat diet. The Journal of nutritional biochemistry. 2020 05; 79(?):108352. doi: 10.1016/j.jnutbio.2020.108352. [PMID: 32145471]
  • Yumi Kitahiro, Hiroshi Ikeda, Hyoung-Tak Im, Eiichi Kodaira, Makio Shibano. Phytochemical characterization of Rosa multiflora Thunb. (Rosaceae) in Japan and South Korea, with a focus on the bioactive flavonol glycoside 'multiflorin A'. Journal of natural medicines. 2019 Jun; 73(3):555-565. doi: 10.1007/s11418-019-01302-x. [PMID: 30949951]
  • Kristóf Csepregi, Péter Teszlák, László Kőrösi, Éva Hideg. Changes in grapevine leaf phenolic profiles during the day are temperature rather than irradiance driven. Plant physiology and biochemistry : PPB. 2019 Apr; 137(?):169-178. doi: 10.1016/j.plaphy.2019.02.012. [PMID: 30797184]
  • Itziar Eseberri, Jonatan Miranda, Arrate Lasa, Andrea Mosqueda-Solís, Susana González-Manzano, Celestino Santos-Buelga, Maria P Portillo. Effects of Quercetin Metabolites on Triglyceride Metabolism of 3T3-L1 Preadipocytes and Mature Adipocytes. International journal of molecular sciences. 2019 Jan; 20(2):. doi: 10.3390/ijms20020264. [PMID: 30641871]
  • Manuela Mandrone, Aline Coqueiro, Ferruccio Poli, Fabiana Antognoni, Young Hae Choi. Identification of a Collagenase-Inhibiting Flavonoid from Alchemilla vulgaris Using NMR-Based Metabolomics. Planta medica. 2018 Aug; 84(12-13):941-946. doi: 10.1055/a-0630-2079. [PMID: 29797306]
  • Yang Liu, Yanni Cao, Shengzuo Fang, Tongli Wang, Zhiqi Yin, Xulan Shang, Wanxia Yang, Xiangxiang Fu. Antidiabetic Effect of Cyclocarya paliurus Leaves Depends on the Contents of Antihyperglycemic Flavonoids and Antihyperlipidemic Triterpenoids. Molecules (Basel, Switzerland). 2018 Apr; 23(5):. doi: 10.3390/molecules23051042. [PMID: 29710841]
  • A Garbetta, L Nicassio, I D'Antuono, A Cardinali, V Linsalata, G Attolico, F Minervini. Influence of in vitro digestion process on polyphenolic profile of skin grape (cv. Italia) and on antioxidant activity in basal or stressed conditions of human intestinal cell line (HT-29). Food research international (Ottawa, Ont.). 2018 04; 106(?):878-884. doi: 10.1016/j.foodres.2018.01.072. [PMID: 29579999]
  • Roger Remy Dresch, Maria Terezinha Kreinecker Dresch, Renata Biegelmeyer, Débora Fretes Argenta, Ricardo Fagundes da Rocha, Helder Ferreira Teixeira, José Cláudio Fonseca Moreira, Amélia Teresinha Henriques. Potential use of secondary products of the agri-food industry for topical formulations and comparative analysis of antioxidant activity of grape leaf polyphenols. Natural product research. 2018 Feb; 32(4):486-492. doi: 10.1080/14786419.2017.1315573. [PMID: 28403634]
  • Cristina Sgherri, Usue Pérez-López, Francesco Micaelli, Jon Miranda-Apodaca, Amaia Mena-Petite, Alberto Muñoz-Rueda, Mike Frank Quartacci. Elevated CO2 and salinity are responsible for phenolics-enrichment in two differently pigmented lettuces. Plant physiology and biochemistry : PPB. 2017 Jun; 115(?):269-278. doi: 10.1016/j.plaphy.2017.04.006. [PMID: 28411511]
  • Sameh R Hussein, Mona M Marzouk, Mona E S Kassem, Rasha R Abdel Latif, Reda S Mohammed. Chemosystematic significance of flavonoids isolated from Diplotaxis acris (Brassicaceae) and related taxa. Natural product research. 2017 Feb; 31(3):347-350. doi: 10.1080/14786419.2016.1226831. [PMID: 27589908]
  • Hyun Soo Jang, Seung In Um, Sung Hee Lee, Wan Kyunn Whang, Young Sil Min, Sun Young Park, Uy Dong Sohn. The protective mechanism of QGC in feline esophageal epithelial cells by interleukin-1β treatment. Archives of pharmacal research. 2017 Feb; 40(2):204-213. doi: 10.1007/s12272-016-0858-x. [PMID: 28012047]
  • Fei Li, Xiao-Yue Sun, Xiao-Wei Li, Tong Yang, Lian-Wen Qi. Enrichment and separation of quercetin-3-O-β-d-glucuronide from lotus leaves (nelumbo nucifera gaertn.) and evaluation of its anti-inflammatory effect. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Jan; 1040(?):186-191. doi: 10.1016/j.jchromb.2016.12.017. [PMID: 27987489]
  • Le-Le Yang, Na Xiao, Xiao-Wei Li, Yong Fan, Raphael N Alolga, Xiao-Yue Sun, Shi-Lei Wang, Ping Li, Lian-Wen Qi. Pharmacokinetic comparison between quercetin and quercetin 3-O-β-glucuronide in rats by UHPLC-MS/MS. Scientific reports. 2016 10; 6(?):35460. doi: 10.1038/srep35460. [PMID: 27775094]
  • Cheng-Hung Chuang, Chiao-Lin Yeh, Shu-Lan Yeh, En-Shyh Lin, Li-Yu Wang, Ying-Hsuna Wang. Quercetin metabolites inhibit MMP-2 expression in A549 lung cancer cells by PPAR-γ associated mechanisms. The Journal of nutritional biochemistry. 2016 07; 33(?):45-53. doi: 10.1016/j.jnutbio.2016.03.011. [PMID: 27260467]
  • Yu Geon Lee, Jeong-Yong Cho, Young-Min Kim, Jae-Hak Moon. Change in Flavonoid Composition and Antioxidative Activity during Fermentation of Onion (Allium cepa L.) by Leuconostoc mesenteroides with Different Salt Concentrations. Journal of food science. 2016 Jun; 81(6):C1385-93. doi: 10.1111/1750-3841.13329. [PMID: 27175820]
  • Chiemi Kamada, Rie Mukai, Akari Kondo, Shinya Sato, Junji Terao. Effect of quercetin and its metabolite on caveolin-1 expression induced by oxidized LDL and lysophosphatidylcholine in endothelial cells. Journal of clinical biochemistry and nutrition. 2016 May; 58(3):193-201. doi: 10.3164/jcbn.16-2. [PMID: 27257344]
  • Shu-Lan Yeh, Yi-Chin Lin, Yi-Ling Lin, Chien-Chun Li, Cheng-Hung Chuang. Comparing the metabolism of quercetin in rats, mice and gerbils. European journal of nutrition. 2016 Feb; 55(1):413-22. doi: 10.1007/s00394-015-0862-9. [PMID: 25691233]
  • Lu Lu Wang, Zhi Chao Zhang, Waseem Hassan, Yu Li, Jun Liu, Jing Shang. Amelioration of free fatty acid-induced fatty liver by quercetin-3-O-β-D-glucuronide through modulation of peroxisome proliferator-activated receptor-alpha/sterol regulatory element-binding protein-1c signaling. Hepatology research : the official journal of the Japan Society of Hepatology. 2016 Feb; 46(2):225-38. doi: 10.1111/hepr.12557. [PMID: 26190035]
  • Alessandro Venditti, Laura Guarcini, Armandodoriano Bianco, Sergio Rosselli, Maurizio Bruno, Felice Senatore. Phytochemical analysis of Achillea ligustica All. from Lipari Island (Aeolian Islands). Natural product research. 2016; 30(8):912-9. doi: 10.1080/14786419.2015.1079188. [PMID: 26327332]
  • Rungnapa Boonpawa, Nooshin Moradi, Albertus Spenkelink, Ivonne M C M Rietjens, Ans Punt. Use of physiologically based kinetic (PBK) modeling to study interindividual human variation and species differences in plasma concentrations of quercetin and its metabolites. Biochemical pharmacology. 2015 Dec; 98(4):690-702. doi: 10.1016/j.bcp.2015.09.022. [PMID: 26441251]
  • Shujing Jiang, Qi Liu, Yixi Xie, Hualiang Zeng, Li Zhang, Xinyu Jiang, Xiaoqing Chen. Separation of five flavonoids from tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) grains via off-line two dimensional high-speed counter-current chromatography. Food chemistry. 2015 Nov; 186(?):153-9. doi: 10.1016/j.foodchem.2014.08.120. [PMID: 25976805]
  • Jonathan G Messer, Robin G Hopkins, Deborah E Kipp. Quercetin Metabolites Up-Regulate the Antioxidant Response in Osteoblasts Isolated From Fetal Rat Calvaria. Journal of cellular biochemistry. 2015 Sep; 116(9):1857-66. doi: 10.1002/jcb.25141. [PMID: 25716194]
  • Flora Tolentino, Priscila Alves de Araújo, Eduardo de Souza Marques, Marcel Petreanu, Sérgio Faloni de Andrade, Rivaldo Niero, Fábio F Perazzo, Paulo César Pires Rosa, Edson Luis Maistro. In vivo evaluation of the genetic toxicity of Rubus niveus Thunb. (Rosaceae) extract and initial screening of its potential chemoprevention against doxorubicin-induced DNA damage. Journal of ethnopharmacology. 2015 Apr; 164(?):89-95. doi: 10.1016/j.jep.2015.02.013. [PMID: 25681544]
  • Karsten Beekmann, Laura Rubió, Laura H J de Haan, Lucas Actis-Goretta, Bart van der Burg, Peter J van Bladeren, Ivonne M C M Rietjens. The effect of quercetin and kaempferol aglycones and glucuronides on peroxisome proliferator-activated receptor-gamma (PPAR-γ). Food & function. 2015 Apr; 6(4):1098-107. doi: 10.1039/c5fo00076a. [PMID: 25765892]
  • R Jimenez, R Lopez-Sepulveda, M Romero, M Toral, A Cogolludo, F Perez-Vizcaino, J Duarte. Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats. Food & function. 2015 Feb; 6(2):409-14. doi: 10.1039/c4fo00818a. [PMID: 25562607]
  • James Daubney, Philip L Bonner, Alan J Hargreaves, John M Dickenson. Cardioprotective and cardiotoxic effects of quercetin and two of its in vivo metabolites on differentiated h9c2 cardiomyocytes. Basic & clinical pharmacology & toxicology. 2015 Feb; 116(2):96-109. doi: 10.1111/bcpt.12319. [PMID: 25203460]
  • Almudena Perez, Susana Gonzalez-Manzano, Rosario Jimenez, Rocío Perez-Abud, Jose M Haro, Antonio Osuna, Celestino Santos-Buelga, Juan Duarte, Francisco Perez-Vizcaino. The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity. Pharmacological research. 2014 Nov; 89(?):11-8. doi: 10.1016/j.phrs.2014.07.005. [PMID: 25076013]
  • Shu-Ting Chan, Yi-Chin Lin, Cheng-Hung Chuang, Rong-Jen Shiau, Jiunn-Wang Liao, Shu-Lan Yeh. Oral and intraperitoneal administration of quercetin decreased lymphocyte DNA damage and plasma lipid peroxidation induced by TSA in vivo. BioMed research international. 2014; 2014(?):580626. doi: 10.1155/2014/580626. [PMID: 24868531]
  • Chao-Zhan Lin, Zhong-Xiang Zhao, Si-Min Xie, Ju-Hua Mao, Chen-Chen Zhu, Xiao-Hui Li, Bairi Zeren-dawa, Kangsa Suolang-qimei, Dun Zhu, Tian-Qin Xiong, Ai-Zhi Wu. Diterpenoid alkaloids and flavonoids from Delphinium trichophorum. Phytochemistry. 2014 Jan; 97(?):88-95. doi: 10.1016/j.phytochem.2013.10.011. [PMID: 24256579]
  • Khem Raj Joshi, Hari Prasad Devkota, Takashi Watanabe, Shoji Yahara. Phenolic compounds from the flowers of Nepalese medicinal plant Aconogonon molle and their DPPH free radical-scavenging activities. Natural product research. 2014; 28(23):2208-10. doi: 10.1080/14786419.2014.915829. [PMID: 24825068]
  • Hideto Kimura, Tomoe Ishihara, Mahoko Michida, Satoshi Ogawa, Takashi Akihiro, Kazushige Yokota. Identification and quantitative analysis of polyphenolic compounds from the indigo plant (Polygonum tinctorium Lour). Natural product research. 2014; 28(7):492-5. doi: 10.1080/14786419.2013.871719. [PMID: 24437998]
  • R S Mohammed, A H Abou Zeid, E A El-Kashoury, A A Sleem, D A Waly. A new flavonol glycoside and biological activities of Adenanthera pavonina L. leaves. Natural product research. 2014; 28(5):282-9. doi: 10.1080/14786419.2013.856903. [PMID: 24289202]
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