Seselin (BioDeep_00000017737)

 

Secondary id: BioDeep_00000001110

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


2H-1-Benzopyran-6-acrylic acid, 5-hydroxy-2,2-dimethyl-, .delta.-lactone

化学式: C14H12O3 (228.0786402)
中文名称: 邪蒿素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 95.45%

分子结构信息

SMILES: CC1(C)C=Cc2c(ccc3ccc(=O)oc23)O1
InChI: InChI=1S/C14H12O3/c1-14(2)8-7-10-11(17-14)5-3-9-4-6-12(15)16-13(9)10/h3-8H,1-2H3

描述信息

Seselin is a member of coumarins. It has a role as a metabolite.
Seselin is a natural product found in Haplophyllum cappadocicum, Haplophyllum dshungaricum, and other organisms with data available.
Constituent of Carum roxburghianum (Bishops weed). Seselin is found in many foods, some of which are sweet orange, herbs and spices, anise, and wild celery.
Seselin is found in anise. Seselin is a constituent of Carum roxburghianum (Bishops weed)
A natural product found in Citropsis articulata.

同义名列表

20 个代谢物同义名

2H-1-Benzopyran-6-acrylic acid, 5-hydroxy-2,2-dimethyl-, .delta.-lactone; 8,8-Dimethyl-2H,8H-benzo[1,2-b:3,4-b]dipyran-2-one, 9CI; 2H,8H-Benzo[1,2-b:3,4-b]dipyran-2-one, 8,8-dimethyl-; 2H,8H-Benzo(1,2-b:3,4-b)dipyran-2-one, 8,8-dimethyl-; 8,8-Dimethyl-2H,8H-benzo(1,2-b:3,4-b)dipyran-2-one; 8,8-Dimethyl-2H,8H-Benzo[1,2-b:3,4-b]dipyran-2-one; 8,8-Dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one #; 8,8-dimethyl-2H,8H-pyrano[2,3-h]chromen-2-one; 8,8-Dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one; 3,4-Di-O-(-)-Camphanoyl-(+)-cis-khellactone; 8,8-DIMETHYLPYRANO[2,3-H]CHROMEN-2-ONE; 8,8-dimethylpyrano[2,3-f]chromen-2-one; 2,2-dimethyl-3-pyreno[65:7,8]coumarin; QUVCQYQEIOLHFZ-UHFFFAOYSA-N; Pyranocoumarin deriv.; Oprea1_187929; Amyrolin; Seseline; Sesalin; Seselin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

38 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yu Wang, Yao Yu, Yi-Ping Hou, Xue-Wei Mao, Zong-Liang Liu, Jian Cui, Bi Wang, Shu Xu, Yi-Yun Qian, Yan-Qin Jiang, Min Wei, Ping-Ping Song. Crucial Role of the Ca2+/CN Signaling Pathway in the Antifungal Activity of Seselin against Botrytis cinerea. Journal of agricultural and food chemistry. 2023 Jun; ?(?):. doi: 10.1021/acs.jafc.3c01474. [PMID: 37313981]
  • Kripa Shankar Nainawat, Sarita Singh, Karishma Agarwal, Hina Iqbal, Poonam Rani, Divya Bhatt, Sana Khan, Debabrata Chanda, Dnyaneshwar Umrao Bawankule, Sudeep Tandon, Feroz Khan, Anil Kumar Gupta, Atul Gupta. Synthesis of 6-alkoxy and 6-hydroxy-alkyl amine derivatives of braylin as vasorelaxing agents. Bioorganic & medicinal chemistry letters. 2023 06; 89(?):129311. doi: 10.1016/j.bmcl.2023.129311. [PMID: 37149230]
  • Anan Athipornchai, Rungnapha Kumpang, Suwanna Semsri. Potential Biological Activities of Clausena Essential Oils for the Treatment of Diabetes. Journal of oleo science. 2021; 70(11):1669-1676. doi: 10.5650/jos.ess19294. [PMID: 34732637]
  • Márcio Santos Soares, Danielle Fernandes da Silva, Jéssica Cristina Amaral, Michelli Masaroli da Silva, Moacir Rossi Forim, Edson Rodrigues-Filho, Maria Fátima das Graças Fernandes da Silva, João Batista Fernandes, Marcos Antônio Machado, Alessandra Alves de Souza, Carlos Henrique Gomes Martins. Rapid differentiation of graft Citrus sinensis with and without Xylella fastidiosa infection by mass spectrometry. Rapid communications in mass spectrometry : RCM. 2020 Sep; 34 Suppl 3(?):e8745. doi: 10.1002/rcm.8745. [PMID: 32053855]
  • Chitra Somu, Hilda Karuppiah, Janarthanan Sundaram. Antiviral activity of seselin from Aegle marmelos against nuclear polyhedrosis virus infection in the larvae of silkworm, Bombyx mori. Journal of ethnopharmacology. 2019 Dec; 245(?):112155. doi: 10.1016/j.jep.2019.112155. [PMID: 31449858]
  • Kinga Ostrowska, Wioletta Olejarz, Małgorzata Wrzosek, Alicja Głuszko, Grażyna Nowicka, Mirosław Szczepański, Ilona B Materek, Anna E Kozioł, Marta Struga. Anticancer effects of O-aminoalkyl derivatives of alloxanthoxyletin and seselin. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Nov; 95(?):1412-1424. doi: 10.1016/j.biopha.2017.09.050. [PMID: 28946189]
  • L Mukandiwa, A Ahmed, J N Eloff, V Naidoo. Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine. Journal of ethnopharmacology. 2013 Dec; 150(3):886-91. doi: 10.1016/j.jep.2013.09.037. [PMID: 24095830]
  • Manish Jain, William R Surin, Ankita Misra, Prem Prakash, Vishal Singh, Vivek Khanna, Satish Kumar, Hefazat H Siddiqui, Kanwal Raj, Manoj K Barthwal, Madhu Dikshit. Antithrombotic activity of a newly synthesized coumarin derivative 3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-N-{2-[3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-propionylamino]-ethyl}-propionamide. Chemical biology & drug design. 2013 Apr; 81(4):499-508. doi: 10.1111/cbdd.12000. [PMID: 23534412]
  • Ahmed Abbaskhan, Muhammed Iqbal Choudhary, Mohammed Nabeel Ghayur, Zeba Parween, Farzana Shaheen, Anwar-ul-Hassan Gilani, Takuro Maruyama, Kiran Iqbal, Yoshisuke Tsuda. Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh. Phytotherapy research : PTR. 2012 May; 26(5):783-6. doi: 10.1002/ptr.3600. [PMID: 22095902]
  • Damien Lacroix, Soizic Prado, Dennis Kamoga, John Kasenene, Bernard Bodo. Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark. Journal of natural products. 2011 Oct; 74(10):2286-9. doi: 10.1021/np2004825. [PMID: 21985060]
  • Tao Feng, Rui-Rui Wang, Xiang-Hai Cai, Yong-Tang Zheng, Xiao-Dong Luo. Anti-human immunodeficiency virus-1 constituents of the bark of Poncirus trifoliata. Chemical & pharmaceutical bulletin. 2010 Jul; 58(7):971-5. doi: 10.1248/cpb.58.971. [PMID: 20606349]
  • Takuro Maruyama, Ahmed Abbaskhan, Muhammad Iqbal Choudhary, Yoshisuke Tsuda, Yukihiro Goda, Michel Farille, Jean-Pierre Reduron. Botanical origin of Indian celery seed (fruit). Journal of natural medicines. 2009 Jul; 63(3):248-53. doi: 10.1007/s11418-009-0321-0. [PMID: 19214654]
  • W J Tsai, Y C Chen, M H Wu, L C Lin, K A Chuang, S C Chang, Y C Kuo. Seselin from Plumbago zeylanica inhibits phytohemagglutinin (PHA)-stimulated cell proliferation in human peripheral blood mononuclear cells. Journal of ethnopharmacology. 2008 Sep; 119(1):67-73. doi: 10.1016/j.jep.2008.05.032. [PMID: 18577441]
  • Vilma Lima, Caio B Silva, Jair Mafezoli, Mirna M Bezerra, M Odorico Moraes, Guilherme S M M Mourão, J Nunes Silva, M Conceição F Oliveira. Antinociceptive activity of the pyranocoumarin seselin in mice. Fitoterapia. 2006 Dec; 77(7-8):574-8. doi: 10.1016/j.fitote.2006.09.005. [PMID: 17055189]
  • H Fortin, S Tomasi, P Jaccard, V Robin, J Boustie. A prenyloxycoumarin from Psiadia dentata. Chemical & pharmaceutical bulletin. 2001 May; 49(5):619-21. doi: 10.1248/cpb.49.619. [PMID: 11383617]