D-Glucose (BioDeep_00000014321)

 

Secondary id: BioDeep_00000002160, BioDeep_00000014485, BioDeep_00000229627, BioDeep_00000271269, BioDeep_00000405203, BioDeep_00000405557, BioDeep_00000784081, BioDeep_00000859908, BioDeep_00001867891, BioDeep_00001892810

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol

化学式: C6H12O6 (180.0634)
中文名称: BETA-D-葡萄糖, α-D-葡萄糖, D-葡萄糖, D-无水葡萄糖, β-D-葡萄糖, 酵母多糖, 葡萄糖, β-D-葡萄糖(含α-D-葡萄糖)
谱图信息: 最多检出来源 Homo sapiens(blood) 20.98%

分子结构信息

SMILES: C(C1C(C(C(C(O1)O)O)O)O)O
InChI: InChI=1/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1

描述信息

Glucose is a monosaccharide containing six carbon atoms and an aldehyde group. It is referred to as an aldohexose. The glucose molecule can exist in an open-chain (acyclic) and ring (cyclic) form, the latter being the result of an intramolecular reaction between the aldehyde C atom and the C-5 hydroxyl group to form an intramolecular hemiacetal. In aqueous solution, both forms are in equilibrium and at pH 7 the cyclic one is predominant. Glucose is a primary source of energy for all living organisms. It is a fundamental metabolite found in all organisms, ranging from bacteria to plants to humans. Most of the world’s glucose is made by plants and algae during photosynthesis from water and carbon dioxide, where it is used to make cellulose (and other polymeric forms of glucose called polysaccharides) that stabilize plant cell walls. Glucose is also found in fruits and other parts of plants in its free state. In animals, glucose can be generated from the breakdown of glycogen in a process known as glycogenolysis. Glucose can also be synthesized de novo in animals. In particular it can be synthesized in the liver and kidneys from non-carbohydrate intermediates, such as pyruvate and glycerol, by a process known as gluconeogenesis. Humans also consume large amounts of glucose as part of their regular diet. Ingested glucose initially binds to the receptor for sweet taste on the tongue in humans. This complex of the proteins T1R2 and T1R3 makes it possible to identify glucose-containing food sources. Glucose in the body mainly comes from food - about 300 g per day for the average adult. In humans, the breakdown of glucose-containing polysaccharides happens partly during chewing by means of the enzyme known as amylase, which is contained in saliva, as well as by other enzymes such as maltase, lactase and sucrase on the brush border of the small intestine. The blood sugar content of a healthy person in the short-time fasting state, e.g. after overnight fasting, is about 70 to 100 mg/dL of blood (4 to 5.5 mM). In blood plasma, the measured values are about 10–15\\\\% higher. Dysregulated metabolism of glucose can lead to a number of diseases including diabetes. Diabetes is a metabolic disorder where the body is unable to regulate levels of glucose in the blood either because of a lack of insulin in the body or the failure, by cells in the body, to respond properly to insulin. Each of these situations can be caused by persistently high elevations of blood glucose levels, through pancreatic burnout and insulin resistance.
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes.
COVID info from WikiPathways
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
alpha-D-glucose is an endogenous metabolite.
alpha-D-glucose is an endogenous metabolite.

同义名列表

36 个代谢物同义名

(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol; BETA-D-GLUCOSE (CONTAINS ALPHA-D-GLUCOSE); Glucose, (beta-D)-isomer; beta-D-Glucopyranoside; Glucose, (DL)-isomer; beta-D-Glucopyranose; β-D-Glucopyranoside; b-D-Glucopyranose; β-D-Glucopyranose; D-Glucopyranoside; beta-D(+)Glucose; alpha-D-Glucose; D-Glucopyranose; beta-D-Glucose; beta-Dextrose; beta-Glucose; b-D-Glucose; β-D-glucose; β-Dextrose; b-Dextrose; β-Glucose; D-Glucose; D Glucose; b-Glucose; glucoside; ZYMOSAN A; dextrose; Glucose; D-GLCP; GLC-OH; D-GLC; beta-D-Glucose; D-Glucose; alpha-D-Glucose; beta-D-Glucose; Hexose



数据库引用编号

40 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(9)

PlantCyc(33)

代谢反应

1109 个相关的代谢反应过程信息。

Reactome(35)

BioCyc(163)

WikiPathways(8)

Plant Reactome(304)

INOH(0)

PlantCyc(535)

COVID-19 Disease Map(0)

PathBank(64)

PharmGKB(0)

93 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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