1,3,5,8-Tetrahydroxyxanthone (BioDeep_00000007774)
Main id: BioDeep_00000229849
human metabolite PANOMIX_OTCML-2023 blood metabolite Volatile Flavor Compounds natural product
代谢物信息卡片
1,3,5,8-Tetrahydroxy-9H-xanthen-9-one
化学式: C13H8O6 (260.0320868)
中文名称: 去甲基雏叶龙胆酮, 1,3,5,8-四羟基x吨酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1(cc(c2c(c1)oc1c(c2=O)c(ccc1O)O)O)O
InChI: InChI=1S/C13H8O6/c14-5-3-8(17)10-9(4-5)19-13-7(16)2-1-6(15)11(13)12(10)18/h1-4,14-17H
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:65480
- KEGG: C10056
- PubChem: 5281626
- HMDB: HMDB0251055
- Metlin: METLIN68100
- ChEMBL: CHEMBL184574
- MetaCyc: CPD-6885
- KNApSAcK: C00002946
- chemspider: 4444945
- CAS: 2980-32-7
- PMhub: MS000021246
- PubChem: 12242
- PDB-CCD: EKU
- 3DMET: B03499
- NIKKAJI: J167.473K
- KNApSAcK: 65480
- LOTUS: LTS0117076
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(2)
代谢反应
5 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(5)
- tetrahydroxyxanthone biosynthesis (from 3-hydroxybenzoate):
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 ⟶ 1,3,5-trihydroxyxanthone + H2O + NADP+ - tetrahydroxyxanthone biosynthesis (from 3-hydroxybenzoate):
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 ⟶ 1,3,5-trihydroxyxanthone + H2O + NADP+ - superpathway of tetrahydroxyxanthone biosynthesis:
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 ⟶ 1,3,7-trihydroxyxanthone + H2O + NADP+ - tetrahydroxyxanthone biosynthesis (from 3-hydroxybenzoate):
2,3',4,6-tetrahydroxybenzophenone + NADPH + O2 ⟶ 1,3,5-trihydroxyxanthone + H2O + NADP+ - superpathway of tetrahydroxyxanthone biosynthesis:
ATP + benzoate + coenzyme A ⟶ AMP + benzoyl-CoA + diphosphate
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
105 个相关的物种来源信息
- 2759 - Eukaryota: LTS0117076
- 21496 - Gentiana: LTS0117076
- 49933 - Gentiana acaulis: 10.1016/J.BMC.2008.03.069
- 49933 - Gentiana acaulis: LTS0117076
- 49939 - Gentiana brachyphylla: LTS0117076
- 442718 - Gentiana brachyphylla subsp. favratii: 10.1016/0305-1978(82)90006-0
- 442718 - Gentiana brachyphylla subsp. favratii: LTS0117076
- 38851 - Gentiana lutea: 10.1016/0305-1978(82)90006-0
- 38851 - Gentiana lutea: LTS0117076
- 1085736 - Gentiana orbicularis: 10.1016/0305-1978(82)90006-0
- 1085736 - Gentiana orbicularis: LTS0117076
- 553057 - Gentiana rubicunda: LTS0117076
- 574900 - Gentiana thunbergii: 10.1055/S-2004-832632
- 574900 - Gentiana thunbergii: 10.1055/S-2006-962408
- 574900 - Gentiana thunbergii: LTS0117076
- 21472 - Gentianaceae: LTS0117076
- 49959 - Gentianella: LTS0117076
- 137095 - Gentianella amarella: 10.1021/NP070690L
- 137095 - Gentianella amarella: LTS0117076
- 49940 - Gentianella campestris:
- 49940 - Gentianella campestris: 10.1002/HLCA.19740570831
- 49940 - Gentianella campestris: 10.1016/0305-1978(82)90006-0
- 49940 - Gentianella campestris: 10.1055/S-2004-832632
- 49940 - Gentianella campestris: LTS0117076
- 137106 - Gentianella florida: 10.1080/09251619708951287
- 137106 - Gentianella florida: LTS0117076
- 2576744 - Gentianella nitida: 10.1055/S-2006-957908
- 2576744 - Gentianella nitida: LTS0117076
- 242218 - Gentianella ramosa: 10.1016/S0031-9422(00)89285-7
- 208027 - Gentianella serotina: 10.1016/0305-1978(82)90006-0
- 208027 - Gentianella serotina: LTS0117076
- 50798 - Gentianopsis: LTS0117076
- 156522 - Gentianopsis barbata: 10.1016/0305-1978(82)90006-0
- 156522 - Gentianopsis barbata: LTS0117076
- 2884939 - Gentianopsis barbata var. stenocalyx: 10.1016/0305-1978(82)90006-0
- 2884939 - Gentianopsis barbata var. stenocalyx: LTS0117076
- 49941 - Gentianopsis ciliata: 10.1016/0305-1978(82)90006-0
- 49941 - Gentianopsis ciliata: LTS0117076
- 84894 - Gentianopsis crinita: 10.1016/0305-1978(82)90006-0
- 84894 - Gentianopsis crinita: LTS0117076
- 669700 - Gentianopsis detonsa: 10.1016/0305-1978(82)90006-0
- 669700 - Gentianopsis detonsa: LTS0117076
- 50801 - Gentianopsis grandis: 10.1016/0305-1978(82)90006-0
- 50801 - Gentianopsis grandis: LTS0117076
- 866904 - Gentianopsis lanceolata: 10.1016/0305-1978(82)90006-0
- 866904 - Gentianopsis lanceolata: LTS0117076
- 50802 - Gentianopsis paludosa: 10.1016/0305-1978(82)90006-0
- 50802 - Gentianopsis paludosa: LTS0117076
- 866906 - Gentianopsis thermalis: 10.1016/0305-1978(82)90006-0
- 866906 - Gentianopsis thermalis: LTS0117076
- 2065894 - Gentianopsis virgata: 10.1016/0305-1978(82)90006-0
- 2065894 - Gentianopsis virgata: LTS0117076
- 9606 - Homo sapiens: -
- 629714 - Hypericaceae: LTS0117076
- 55962 - Hypericum: LTS0117076
- 268996 - Hypericum henryi: 10.1002/CBDV.200900009
- 268996 - Hypericum henryi: LTS0117076
- 26339 - Iridaceae: LTS0117076
- 26378 - Iris: LTS0117076
- 995810 - Iris nigricans: 10.1016/0031-9422(94)00641-6
- 995810 - Iris nigricans: LTS0117076
- 4447 - Liliopsida: LTS0117076
- 3398 - Magnoliopsida: LTS0117076
- 35493 - Streptophyta: LTS0117076
- 39241 - Swertia: LTS0117076
- 137887 - Swertia chirayita: 10.1002/JPS.2600620614
- 137887 - Swertia chirayita: 10.1080/14786410600906319
- 137887 - Swertia chirayita: LTS0117076
- 166614 - Swertia ciliata: 10.1080/14786410600906319
- 166614 - Swertia ciliata: LTS0117076
- 166614 - Swertia ciliata: NA
- 3053917 - Swertia davidii: LTS0117076
- 559635 - Swertia dilatata: 10.1080/14786410600906319
- 559635 - Swertia dilatata: LTS0117076
- 137891 - Swertia erythrosticta: 10.1080/14786410600906319
- 137891 - Swertia erythrosticta: LTS0117076
- 137129 - Swertia japonica:
- 137129 - Swertia japonica: 10.1007/BF02675902
- 137129 - Swertia japonica: 10.1080/14786410600906319
- 137129 - Swertia japonica: 10.1248/CPB.32.2290
- 137129 - Swertia japonica: 10.1248/YAKUSHI1947.89.3_410
- 137129 - Swertia japonica: LTS0117076
- 1460258 - Swertia lawii:
- 1460258 - Swertia lawii: 10.1016/S0031-9422(00)98635-7
- 1460258 - Swertia lawii: 10.1080/14786410600906319
- 1460258 - Swertia lawii: LTS0117076
- 137130 - Swertia macrosperma:
- 137130 - Swertia macrosperma: 10.1016/0031-9422(89)80400-5
- 137130 - Swertia macrosperma: 10.1080/14786410600906319
- 137130 - Swertia macrosperma: LTS0117076
- 363513 - Swertia nervosa: 10.1080/14786410600906319
- 363513 - Swertia nervosa: LTS0117076
- 559637 - Swertia paniculata: 10.1080/14786410600906319
- 559637 - Swertia paniculata: LTS0117076
- 676131 - Swertia pseudochinensis: 10.1248/BPB.28.534
- 676131 - Swertia pseudochinensis: LTS0117076
- 137132 - Swertia racemosa: 10.1080/14786410600906319
- 137132 - Swertia racemosa: LTS0117076
- 363515 - Swertia souliei:
- 363515 - Swertia souliei: 10.1016/S0031-9422(00)98635-7
- 363515 - Swertia souliei: 10.1080/14786410600906319
- 363515 - Swertia souliei: LTS0117076
- 1205789 - Swertia teres: 10.1080/14786410600906319
- 58023 - Tracheophyta: LTS0117076
- 33090 - Viridiplantae: LTS0117076
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kai Ren, He Su, Li-Juan Lv, Le-Tai Yi, Xue Gong, Lian-Sheng Dang, Rui-Fen Zhang, Min-Hui Li. Effects of Four Compounds from Gentianella acuta (Michx.) Hulten on Hydrogen Peroxide-Induced Injury in H9c2 Cells.
BioMed research international.
2019; 2019(?):2692970. doi:
10.1155/2019/2692970. [PMID: 30800665] - Hong-Bo Xiao, Zhi-Liang Sun, Nan Zhou. 1,3,5,8-tetrahydroxyxanthone regulates ANGPTL3-LPL pathway to lessen the ketosis in mice.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2012 May; 46(1-2):26-31. doi:
10.1016/j.ejps.2012.02.001. [PMID: 22342712] - Fuqiang Jiang, Xuemei Zhang, Yunbao Ma, Chang'an Geng, Zhiyong Jiang, Jijun Chen. [Chemical constituents of Swertia hispidicalyx].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Aug; 36(16):2215-8. doi:
. [PMID: 22097333] - Zong-Ping Zheng, Qin Zhu, Chun-Lin Fan, Hui-Yuan Tan, Mingfu Wang. Phenolic tyrosinase inhibitors from the stems of Cudrania cochinchinensis.
Food & function.
2011 May; 2(5):259-64. doi:
10.1039/c1fo10033e. [PMID: 21779564] - Aleksandra Isakovic, Teodora Jankovic, Ljubica Harhaji, Sladjana Kostic-Rajacic, Zoran Nikolic, Vlatka Vajs, Vladimir Trajkovic. Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements.
Bioorganic & medicinal chemistry.
2008 May; 16(10):5683-94. doi:
10.1016/j.bmc.2008.03.069. [PMID: 18406151] - . .
.
. doi:
. [PMID: 12846828]