Bellidin (BioDeep_00000229849)

PANOMIX_OTCML-2023 Volatile Flavor Compounds

代谢物信息卡片

1,3,5,8-Tetrahydroxyxanthone; Desmethylbellidifolin

化学式: C13H8O6 (260.0320868)
中文名称: 1,3,5,8-四羟基山酮, 去甲基雏菊叶龙胆酮, 去甲基雏叶龙胆酮, 1,3,5,8-四羟基x吨酮
谱图信息: 最多检出来源 Viridiplantae(plant) 2.06%

分子结构信息

SMILES: c1(cc(c2c(c1)oc1c(c2=O)c(ccc1O)O)O)O
InChI: InChI=1S/C13H8O6/c14-5-3-8(17)10-9(4-5)19-13-7(16)2-1-6(15)11(13)12(10)18/h1-4,14-17H

描述信息

Bellidin is a member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris. It has a role as a metabolite, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a mutagen, an antioxidant and a radical scavenger. It is a member of xanthones and a tetrol. It is functionally related to a xanthone.
1,3,5,8-Tetrahydroxyxanthone is a natural product found in Gentiana orbicularis, Swertia teres, and other organisms with data available.
A member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris.

同义名列表

27 个代谢物同义名

1,3,5,8-Tetrahydroxyxanthone; Desmethylbellidifolin; 1,3,5,8-tetrakis(oxidanyl)xanthen-9-one; 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-; 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one; Xanthen-9-one, 1,3,5,8-tetrahydroxy-; 1,3,5,8-Tetrahydroxy-xanthen-9-one; 1,3,5,8-Tetrahydroxyxanthone,85\\%; 1,3,5,8-Tetrahydroxyxanthen-9-one; 1,3,5,8-Tetrahyroxyxanthen-9-one; 1,3,5,8-Tetrahydroxylxanthone; 1,3,5,8-Tetrahydroxyxanthone; 1,3,5,8-Tetrahdroxyyxanthone; MPXAWSABMVLIBU-UHFFFAOYSA-N; DESMETHYLBELLIDIFOLINE; Desmethylbellidifolin; Demethylbellidifolin; Tetrahydroxyxanthone; Desmethybellidifolin; Xanthen-9-one, 1.0; NORBELLIDIFOLIN; Norbellidifodin; UNII-G78B8Y1AI5; G78B8Y1AI5; Bellidin; EKU; Demethylbellidifolin; 1,3,5,8-Tetrahydroxyxanthone

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:65480
KEGG: C10056
PubChem: 5281626
ChEMBL: CHEMBL184574
ChemIDplus: 0002980327
KNApSAcK: C00002946
chemspider: 4444945
CAS: 2980-32-7
medchemexpress: HY-N2050
MetaboLights: MTBLC65480
PubChem: 12242
PDB-CCD: EKU
3DMET: B03499
NIKKAJI: J167.473K
KNApSAcK: 65480

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

36 个相关的物种来源信息

49933 - Gentiana acaulis: 10.1016/J.BMC.2008.03.069
38851 - Gentiana lutea: 10.1016/0305-1978(82)90006-0
1085736 - Gentiana orbicularis: 10.1016/0305-1978(82)90006-0
574900 - Gentiana thunbergii: 10.1055/S-2006-962408
137095 - Gentianella amarella: 10.1021/NP070690L
49940 - Gentianella campestris:
137106 - Gentianella florida: 10.1080/09251619708951287
2576744 - Gentianella nitida: 10.1055/S-2006-957908
242218 - Gentianella ramosa: 10.1016/S0031-9422(00)89285-7
208027 - Gentianella serotina: 10.1016/0305-1978(82)90006-0
156522 - Gentianopsis barbata: 10.1016/0305-1978(82)90006-0
2884939 - Gentianopsis barbata var. stenocalyx: 10.1016/0305-1978(82)90006-0
49941 - Gentianopsis ciliata: 10.1016/0305-1978(82)90006-0
84894 - Gentianopsis crinita: 10.1016/0305-1978(82)90006-0
669700 - Gentianopsis detonsa: 10.1016/0305-1978(82)90006-0
50801 - Gentianopsis grandis: 10.1016/0305-1978(82)90006-0
866904 - Gentianopsis lanceolata: 10.1016/0305-1978(82)90006-0
50802 - Gentianopsis paludosa: 10.1016/0305-1978(82)90006-0
866906 - Gentianopsis thermalis: 10.1016/0305-1978(82)90006-0
2065894 - Gentianopsis virgata: 10.1016/0305-1978(82)90006-0
268996 - Hypericum henryi: 10.1002/CBDV.200900009
995810 - Iris nigricans: 10.1016/0031-9422(94)00641-6
137887 - Swertia chirayita: 10.1002/JPS.2600620614
166614 - Swertia ciliata: 10.1080/14786410600906319
559635 - Swertia dilatata: 10.1080/14786410600906319
137891 - Swertia erythrosticta: 10.1080/14786410600906319
137129 - Swertia japonica:
1460258 - Swertia lawii:
137130 - Swertia macrosperma:
363513 - Swertia nervosa: 10.1080/14786410600906319
559637 - Swertia paniculata: 10.1080/14786410600906319
676131 - Swertia pseudochinensis: 10.1248/BPB.28.534
137132 - Swertia racemosa: 10.1080/14786410600906319
363515 - Swertia souliei:
1205789 - Swertia teres: 10.1080/14786410600906319
33090 - 獐牙菜: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Kai Ren, He Su, Li-Juan Lv, Le-Tai Yi, Xue Gong, Lian-Sheng Dang, Rui-Fen Zhang, Min-Hui Li. Effects of Four Compounds from Gentianella acuta (Michx.) Hulten on Hydrogen Peroxide-Induced Injury in H9c2 Cells. BioMed research international. 2019; 2019(?):2692970. doi: 10.1155/2019/2692970. [PMID: 30800665]
Hong-Bo Xiao, Zhi-Liang Sun, Nan Zhou. 1,3,5,8-tetrahydroxyxanthone regulates ANGPTL3-LPL pathway to lessen the ketosis in mice. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2012 May; 46(1-2):26-31. doi: 10.1016/j.ejps.2012.02.001. [PMID: 22342712]
Fuqiang Jiang, Xuemei Zhang, Yunbao Ma, Chang'an Geng, Zhiyong Jiang, Jijun Chen. [Chemical constituents of Swertia hispidicalyx]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Aug; 36(16):2215-8. doi: . [PMID: 22097333]
Zong-Ping Zheng, Qin Zhu, Chun-Lin Fan, Hui-Yuan Tan, Mingfu Wang. Phenolic tyrosinase inhibitors from the stems of Cudrania cochinchinensis. Food & function. 2011 May; 2(5):259-64. doi: 10.1039/c1fo10033e. [PMID: 21779564]
Aleksandra Isakovic, Teodora Jankovic, Ljubica Harhaji, Sladjana Kostic-Rajacic, Zoran Nikolic, Vlatka Vajs, Vladimir Trajkovic. Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements. Bioorganic & medicinal chemistry. 2008 May; 16(10):5683-94. doi: 10.1016/j.bmc.2008.03.069. [PMID: 18406151]
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