Melanin (BioDeep_00000606593)

   

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Melanin

化学式: C18H10N2O4 (318.064054)
中文名称: 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素, 黑色素
谱图信息: 最多检出来源 Anoectochilus roxburghii(viridiplantae) 45.45%

分子结构信息

SMILES: CC1=C2C3=C(C4=CNC5=C(C(=O)C(=O)C(=C45)C3=CN2)C)C(=O)C1=O
InChI: InChI=1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

描述信息

同义名列表

1 个代谢物同义名

Melanin



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jun Chen, Wenyi Ye. Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification. Pharmaceutical biology. 2024 Dec; 62(1):296-313. doi: 10.1080/13880209.2024.2330609. [PMID: 38555860]
  • Chaodong Qiu, Zhenyu Liu. Positive selection and functional diversification of transcription factor Cmr1 homologs in Alternaria. Applied microbiology and biotechnology. 2024 Dec; 108(1):133. doi: 10.1007/s00253-023-12893-7. [PMID: 38229332]
  • Xiaoling Ma, Ablajan Turak, Rahima Abdulla, Maitinuer Maiwulanjiang, Qingling Ma, Tao Wu, Haji Akber Aisa. Spectrum-effect relationship between ultra-performance liquid chromatography fingerprints and melanogenic effect of Vernonia anthelmintica effective part. Biomedical chromatography : BMC. 2024 Jun; 38(6):e5863. doi: 10.1002/bmc.5863. [PMID: 38506419]
  • Yang-Yang Liu, Yue Zhang, Ling Jiang, Qing-Yu Lu, Rui-Han Ye, Zhen-Yu Guo, Yun-Li Zhao, Xiao-Dong Luo. The whitening effect of cuscutin responsible for traditional use of Bergenia purpurascens. Journal of ethnopharmacology. 2024 May; 326(?):117933. doi: 10.1016/j.jep.2024.117933. [PMID: 38382653]
  • Yuan Zhu, Jinhui Xu, Xiuzu Song, Wenzhong Xiang. Comparative study of melasma in patients before and after treatment based on lipomics. Lipids in health and disease. 2024 May; 23(1):138. doi: 10.1186/s12944-024-02130-z. [PMID: 38734619]
  • Zhixiong Chen, Ni Hong, Cui Yan, Zhongbo Zheng, Jie Xi, Ping Cao. The potential of Paeonia lactiflora pall seeds oil as a pure natural cosmetics raw material: In Vitro findings. Journal of cosmetic dermatology. 2024 May; 23(5):1875-1883. doi: 10.1111/jocd.16204. [PMID: 38450923]
  • Guziliayi Kuerban, Ablajan Turak, Nurmirza Boymirzayevich Begmatov, Jiangyu Zhao, Haji Akber Aisa. Chemical Composition of Artemisia Scoparia and Their Bioactivities. Chemistry & biodiversity. 2024 May; 21(5):e202400414. doi: 10.1002/cbdv.202400414. [PMID: 38500337]
  • Bo Li, Yong Jia, Le Xu, Shuo Zhang, Zhoukai Long, Rong Wang, Ying Guo, Wenying Zhang, Chunhai Jiao, Chengdao Li, Yanhao Xu. Transcriptional convergence after repeated duplication of an amino acid transporter gene leads to the independent emergence of the black husk/pericarp trait in barley and rice. Plant biotechnology journal. 2024 May; 22(5):1282-1298. doi: 10.1111/pbi.14264. [PMID: 38124464]
  • Pan Li, Shen Shen, Jingzhe Jia, Hehe Sun, Hang Zhu, Ning Wei, Bo Yu, Aamir Sohail, Di Wu, Fanli Zeng, Zhimin Hao, Jingao Dong. The catalytic subunit of type 2A protein phosphatase negatively regulates conidiation and melanin biosynthesis in Setosphaeria turcica. International journal of biological macromolecules. 2024 May; 266(Pt 2):131149. doi: 10.1016/j.ijbiomac.2024.131149. [PMID: 38556232]
  • Yifei Wu, Jiayu Zhang, Sha Du, Xiaochuan Wang, Jinrong Li, Yi Chen, Hongying Zhou, Su Gao, Yongrong Li, Xiuhong Liu. Combination of 308-nm excimer laser and piperine promotes melanocyte proliferation, migration, and melanin content production via the miR-328/SFRP1 axis. Photodermatology, photoimmunology & photomedicine. 2024 May; 40(3):e12970. doi: 10.1111/phpp.12970. [PMID: 38685665]
  • Byeong Min Choi, Minkyeong Kim, Hyehyun Hong, Tae-Jin Park, Changmu Kim, Jin-Soo Park, Won-Jae Chi, Seung-Young Kim. Melanin Inhibitory Effect of Tuber himalayense Isolated in Incheon, Korea. Journal of microbiology and biotechnology. 2024 Apr; 34(4):949-957. doi: 10.4014/jmb.2311.11021. [PMID: 38480002]
  • Sheng-Wei Hong, Yu-Feng Wang, Yu-Jiao Chen, Kai-Yu Zhang, Pei-Yao Chen, Hua-Xi Hang, Hui-Lin Yin, Ping Xu, Cheng Tan. Integrative pharmacology reveals the mechanisms of Erzhi pills, A traditional Chinese formulation, stimulating melanogenesis. Journal of ethnopharmacology. 2024 Apr; 324(?):117617. doi: 10.1016/j.jep.2023.117617. [PMID: 38142876]
  • Siji Zhao, Ruya Yin, Mengwei Zhang, Ziqi Zhai, Zhen Shen, Yan Mou, Dan Xu, Ligang Zhou, Daowan Lai. Efficient gene editing in the slow-growing, non-sporulating, melanized, endophytic fungus Berkleasmium sp. Dzf12 using a CRISPR/Cas9 system. World journal of microbiology & biotechnology. 2024 Apr; 40(6):176. doi: 10.1007/s11274-024-03988-y. [PMID: 38652405]
  • Juhee Cho, Meriem Bejaoui, Kenichi Tominaga, Hiroko Isoda. Comparative Analysis of Olive-Derived Phenolic Compounds' Pro-Melanogenesis Effects on B16F10 Cells and Epidermal Human Melanocytes. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084479. [PMID: 38674064]
  • Sobarathne Senel Sanjaya, Mi Hyeon Park, Wisurumuni Arachchilage Hasitha Maduranga Karunarathne, Kyoung Tae Lee, Yung Hyun Choi, Chang-Hee Kang, Mi-Haw Lee, Min-Jeong Jung, Hyung Won Ryu, Gi-Young Kim. Inhibition of α-melanocyte-stimulating hormone-induced melanogenesis and molecular mechanisms by polyphenol-enriched fraction of Tagetes erecta L. flower. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Apr; 126(?):155442. doi: 10.1016/j.phymed.2024.155442. [PMID: 38394730]
  • Song Liu, Yu Hou, Ya-Jun Shi, Nan Zhang, Yi-Guang Hu, Wen-Ming Chen, Ji-Liang Zhang. Triphenyltin induced darker body coloration by disrupting melanocortin system and pteridine metabolic pathway in a reef fish, Amphiprion ocellaris. Ecotoxicology and environmental safety. 2024 Apr; 274(?):116177. doi: 10.1016/j.ecoenv.2024.116177. [PMID: 38461573]
  • Manxiong Dai, Shuo Qi, Xingyang Zhao, Lei Zhou, Quanneng Luo, Xiong Teng, Wei Cheng, Ning Zhou, Hongwen Liu, Kang Chen. JS-K Combined with a Melanin-Based Theranostic Agent: A Novel Sequential Delivery Strategy to Enhance the Near-Infrared Fluorescence Imaging of Pancreatic Ductal Adenocarcinoma. Analytical chemistry. 2024 Mar; 96(10):4103-4110. doi: 10.1021/acs.analchem.3c04914. [PMID: 38427614]
  • Muneeba Zubair Alam, Clinton Emeka Okonkwo, João P Cachaneski-Lopes, Carlos F O Graeff, Augusto Batagin-Neto, Saeed Tariq, Sabu Varghese, Matthew J O'Connor, Abuzar E Albadri, J Beau W Webber, Mohammed Tarique, Mutamed Ayyash, Afaf Kamal-Eldin. Date fruit melanin is primarily based on (-)-epicatechin proanthocyanidin oligomers. Scientific reports. 2024 02; 14(1):4863. doi: 10.1038/s41598-024-55467-x. [PMID: 38418836]
  • Ruojun Du, Lichun Ye, Xinyan Chen, Yan Meng, Lei Zhou, Qiao Chen, Guohua Zheng, Junjie Hu, Zhaohua Shi. Screening of Key Components for Melanogenesis Inhibition of Polygonum cuspidatum Extract Based on the Spectrum-Effect Relationship and Molecular Docking. Molecules (Basel, Switzerland). 2024 Feb; 29(4):. doi: 10.3390/molecules29040857. [PMID: 38398609]
  • Xiaojin Liu, Xiaobing Lv, Tiancheng Ji, Haoya Hu, Lei Chang. Gynostemma pentaphyllum Makino extract induces hair growth and exhibits an anti-graying effect via multiple mechanisms. Journal of cosmetic dermatology. 2024 Feb; 23(2):648-657. doi: 10.1111/jocd.15963. [PMID: 37649302]
  • Xue Chen, Puze Li, Ban Luo, Cheng Song, Meichan Wu, Yuzhu Yao, Dongdong Wang, Xuyu Li, Bo Hu, Suting He, Yuan Zhao, Chongyi Wang, Xiangliang Yang, Jun Hu. Surface Mineralization of Engineered Bacterial Outer Membrane Vesicles to Enhance Tumor Photothermal/Immunotherapy. ACS nano. 2024 Jan; 18(2):1357-1370. doi: 10.1021/acsnano.3c05714. [PMID: 38164903]
  • Mahanthi Vasu, Sonika Ahlawat, Pooja Chhabra, Upasna Sharma, Reena Arora, Rekha Sharma, M A Mir, Manoj Kumar Singh. Genetic insights into fiber quality, coat color and adaptation in Changthangi and Muzzafarnagri sheep: A comparative skin transcriptome analysis. Gene. 2024 Jan; 891(?):147826. doi: 10.1016/j.gene.2023.147826. [PMID: 37748630]
  • Jinpeng Lv, Ximei Zhang, Xiaohong An, Yan Cao, Duo Meng, Kun Zou, Rongyin Gao, Ruzhi Zhang. The inhibition of VDAC1 oligomerization promotes pigmentation through the CaMK-CRTCs/CREB-MITF pathway. Experimental cell research. 2024 01; 434(2):113874. doi: 10.1016/j.yexcr.2023.113874. [PMID: 38070860]
  • Xinping Kuai, Dandan Shao, Shengyu Wang, Pu-Yeh Wu, Yan Wu, Xuexue Wang. Neuromelanin-sensitive MRI of the substantia nigra distinguishes bipolar from unipolar depression. Cerebral cortex (New York, N.Y. : 1991). 2024 01; 34(1):. doi: 10.1093/cercor/bhad423. [PMID: 37955650]
  • Ruiyi Lin, Fanglu Zhao, Taimin Xiong, Lianjie Lai, Huihuang Li, Weilong Lin, Tianfang Xiao, Weimin Lin. Genetic mapping identifies SNP mutations in MITF-M promoter associated with melanin formation in Putian black duck. Poultry science. 2024 Jan; 103(1):103191. doi: 10.1016/j.psj.2023.103191. [PMID: 37980740]
  • Yaoyao Xiao, Lele Zhou, Wenkang Tao, Xuan Yang, Junying Li, Rulin Wang, Yanan Zhao, Can Peng, Caiyun Zhang. Preparation of paeoniflorin-glycyrrhizic acid complex transethosome gel and its preventive and therapeutic effects on melasma. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2024 Jan; 192(?):106664. doi: 10.1016/j.ejps.2023.106664. [PMID: 38061662]
  • Wenbin Xu, Ren Mu, Tuya Gegen, Jiaxiang Luo, Yang Xiao, Shunnian Ou, Qi Wu, Yongsong Zuo, Zhi Chen, Fangwei Li. Comparative analysis of hepatic transcriptomes and metabolomes of Changshun green-shell laying hens based on different green eggshell color intensities. Poultry science. 2024 Jan; 103(1):103220. doi: 10.1016/j.psj.2023.103220. [PMID: 37980748]
  • Yon-Suk Kim, Eun-Bin Lee, Ye-Ji Yu, Ga-Won Kim, Woo-Jung Kim, Dong-Kug Choi. Ethyl Acetate Fraction from a Catalpa ovata G. Don Extract Inhibits ɑ-MSH-Induced Melanogenesis through the cAMP/CREB Pathway. International journal of molecular sciences. 2023 Dec; 25(1):. doi: 10.3390/ijms25010151. [PMID: 38203322]
  • Lingtao Duan, Li Wang, Weilun Chen, Zhenrui He, Erxun Zhou, Yiming Zhu. Deficiency of ChPks and ChThr1 Inhibited DHN-Melanin Biosynthesis, Disrupted Cell Wall Integrity and Attenuated Pathogenicity in Colletotrichum higginsianum. International journal of molecular sciences. 2023 Nov; 24(21):. doi: 10.3390/ijms242115890. [PMID: 37958874]
  • Yi-Chi Chen, Yang-Yang Liu, Liqiang Chen, Dong-Mei Tang, YunLi Zhao, Xiao-Dong Luo. Antimelanogenic Effect of Isoquinoline Alkaloids from Plumula Nelumbinis. Journal of agricultural and food chemistry. 2023 Nov; 71(43):16090-16101. doi: 10.1021/acs.jafc.3c03784. [PMID: 37856847]
  • Huan Li, Ruo-Cheng Sheng, Chen-Ning Zhang, Li-Chao Wang, Min Li, Ya-Hong Wang, Yu-Hang Qiao, Steven J Klosterman, Jie-Yin Chen, Zhi-Qiang Kong, Krishna V Subbarao, Feng-Mao Chen, Dan-Dan Zhang. Two zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae. BMC biology. 2023 10; 21(1):237. doi: 10.1186/s12915-023-01697-w. [PMID: 37904147]
  • François Maillard, Talia J Michaud, Craig R See, Lang C DeLancey, Steven J Blazewicz, Jeffrey A Kimbrel, Jennifer Pett-Ridge, Peter G Kennedy. Melanization slows the rapid movement of fungal necromass carbon and nitrogen into both bacterial and fungal decomposer communities and soils. mSystems. 2023 08; 8(4):e0039023. doi: 10.1128/msystems.00390-23. [PMID: 37338274]
  • Colin Barry, Edward Wang. Racially fair pupillometry measurements for RGB smartphone cameras using the far red spectrum. Scientific reports. 2023 08; 13(1):13841. doi: 10.1038/s41598-023-40796-0. [PMID: 37620445]
  • WesamEldin I A Saber, Abeer A Ghoniem, Fatimah O Al-Otibi, Mohammed S El-Hersh, Noha M Eldadamony, Farid Menaa, Khaled M Elattar. A comparative study using response surface methodology and artificial neural network towards optimized production of melanin by Aureobasidium pullulans AKW. Scientific reports. 2023 08; 13(1):13545. doi: 10.1038/s41598-023-40549-z. [PMID: 37598271]
  • Maria Dittrich, Carlos Paulo, Nicole Knabe, Heinz Sturm, Vladimir Zaitsev, Anna A Gorbushina. Microscopic Raman study of fungal pigment using the genetically amenable rock inhabitant Knufia petricola as a model organism. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2023 Aug; 303(?):123250. doi: 10.1016/j.saa.2023.123250. [PMID: 37625274]
  • Erin C Carr, Quin Barton, Sarah Grambo, Mitchell Sullivan, Cecile M Renfro, Alan Kuo, Jasmyn Pangilinan, Anna Lipzen, Keykhosrow Keymanesh, Emily Savage, Kerrie Barry, Igor V Grigoriev, Wayne R Riekhof, Steven D Harris. Characterization of a novel polyextremotolerant fungus, Exophiala viscosa, with insights into its melanin regulation and ecological niche. G3 (Bethesda, Md.). 2023 08; 13(8):. doi: 10.1093/g3journal/jkad110. [PMID: 37221014]
  • Xiaoyu Yang, Yonghong Chen, Longlong Zhang, Jiangbo He, Qunfu Wu, Shuhong Li, Donglou Wang, Jianghui Gou, Zhuang Wu, Keqin Zhang, Shenghong Li, Xuemei Niu. Melanin precursors mediated adaption to temperature changes in fungus and animal via inhibition of lipid-mediated ferroptosis. Science China. Life sciences. 2023 08; 66(8):1800-1817. doi: 10.1007/s11427-022-2265-6. [PMID: 36949229]
  • Chaiwat Monmai, Jin-Suk Kim, Joong Hyoun Chin, Sanghyun Lee, So-Hyeon Baek. Inhibitory Effects of Polyphenol- and Flavonoid-Enriched Rice Seed Extract on Melanogenesis in Melan-a Cells via MAPK Signaling-Mediated MITF Downregulation. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411841. [PMID: 37511600]
  • Min-A Ahn, Jinsu Lee, Tae Kyung Hyun. Histone Deacetylase Inhibitor, Sodium Butyrate-Induced Metabolic Modulation in Platycodon grandiflorus Roots Enhances Anti-Melanogenic Properties. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411804. [PMID: 37511563]
  • Zühal Bayrakçeken Güven, Iclal Saracoglu, Akito Nagatsu, Mustafa Abdullah Yilmaz, A Ahmet Basaran. Anti-tyrosinase and antimelanogenic effect of cinnamic acid derivatives from Prunus mahaleb L.: Phenolic composition, isolation, identification and inhibitory activity. Journal of ethnopharmacology. 2023 Jun; 310(?):116378. doi: 10.1016/j.jep.2023.116378. [PMID: 36924865]
  • Zitong Yuan, Yiwei Li, Yuke He, Kun Qian, Yongqiang Zhang. Differential Analysis of Three Copper-Based Nanomaterials with Different Morphologies to Suppress Alternaria alternata and Safety Evaluation. International journal of molecular sciences. 2023 Jun; 24(11):. doi: 10.3390/ijms24119673. [PMID: 37298626]
  • Krystian Mokrzyński, Michał Sarna, Tadeusz Sarna. Photoreactivity and phototoxicity of experimentally photodegraded hair melanosomes from individuals of different skin phototypes. Journal of photochemistry and photobiology. B, Biology. 2023 Jun; 243(?):112704. doi: 10.1016/j.jphotobiol.2023.112704. [PMID: 37030132]
  • R Keating Godfrey, Sarah E Britton, Shova Mishra, Jay K Goldberg, Akito Y Kawahara. A high-quality, long-read genome assembly of the whitelined sphinx moth (Lepidoptera: Sphingidae: Hyles lineata) shows highly conserved melanin synthesis pathway genes. G3 (Bethesda, Md.). 2023 06; 13(6):. doi: 10.1093/g3journal/jkad090. [PMID: 37119801]
  • Miral O Sabry, Omar M Sabry, Giovanni Caprioli. Intriguing diverse chemistry and unique molecular mechanisms: new medicines with diverse pharmacological activities from cephalopods ink. Natural product research. 2023 Jun; 37(11):1909-1916. doi: 10.1080/14786419.2022.2119567. [PMID: 36067513]
  • Tao Liu, Jun Qin, Wenjing Shang, Jieyin Chen, Krishna V Subbarao, Xiaoping Hu. The Phosphatase VdPtc3 Regulates Virulence in Verticillium dahliae by Interacting with VdAtg1. Phytopathology. 2023 Jun; 113(6):1048-1057. doi: 10.1094/phyto-09-22-0320-r. [PMID: 36449525]
  • Muhammad Shahzad Khan, Qazi Adnan, Naveed Akhtar. Profiling of phytochemicals using LC-ESI-MS2 , in vitro, in vivo characterization and cosmeceutical effects of Alpinia galanga (wild) extract loaded emulgel. Journal of cosmetic dermatology. 2023 May; 22(5):1628-1641. doi: 10.1111/jocd.15623. [PMID: 36718832]
  • Jiling Xiao, Ke Yang, Zhihuai Liang, Yi Zhang, Lin Wei. BCB1, a member of the acyl-coenzyme A synthetase family, regulates the morphogenesis and pathogenicity of Botrytis cinerea. Archives of microbiology. 2023 Apr; 205(5):206. doi: 10.1007/s00203-023-03540-w. [PMID: 37160639]
  • Xinyu Qin, Chengming Tian, Fanli Meng. Comparative Transcriptome Analysis Reveals the Effect of the DHN Melanin Biosynthesis Pathway on the Appressorium Turgor Pressure of the Poplar Anthracnose-Causing Fungus Colletotrichum gloeosporioides. International journal of molecular sciences. 2023 Apr; 24(8):. doi: 10.3390/ijms24087411. [PMID: 37108573]
  • Shan Yang, Zhekun Wang, Yunwei Hu, Kaile Zong, Xingjiang Zhang, Hui Ke, Pan Wang, Yuyo Go, Xi Hui Felicia Chan, Jianxin Wu, Qing Huang. Hydrolyzed Conchiolin Protein (HCP) Extracted from Pearls Antagonizes both ET-1 and α-MSH for Skin Whitening. International journal of molecular sciences. 2023 Apr; 24(8):. doi: 10.3390/ijms24087471. [PMID: 37108635]
  • Hui-Hao Tang, Yi-Fan Zhang, Li-Li Yang, Chen Hong, Kai-Xian Chen, Yi-Ming Li, Hua-Li Wu. Serotonin/5-HT7 receptor provides an adaptive signal to enhance pigmentation response to environmental stressors through cAMP-PKA-MAPK, Rab27a/RhoA, and PI3K/AKT signaling pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023 04; 37(4):e22893. doi: 10.1096/fj.202201352rr. [PMID: 36961387]
  • Yifan Zhang, Chen Hong, Chenqi Zhang, Huiliang Li, Wenting Lv, Kang Cheng, Zhi Lv, Yiming Li, Huali Wu. SP/5-HT functional cross-talk in melanin biosynthesis: interaction between NK1R and 5-HT2AR. European journal of dermatology : EJD. 2023 04; 33(2):160-162. doi: 10.1684/ejd.2023.4446. [PMID: 37431119]
  • Abul Taher Mohammed Rafiqul Islam, Keita Shinzato, Hiroki Miyaoka, Kenji Komaguchi, Kanae Koike, Kenji Arakawa, Kenji Kitamura, Nobukazu Tanaka. Isolation and characterization of blackish-brown BY2-melanin accumulated in cultured tobacco BY-2 cells. Bioscience, biotechnology, and biochemistry. 2023 Mar; 87(4):395-410. doi: 10.1093/bbb/zbac214. [PMID: 36592962]
  • Yuchu Zhao, Shiting Yu, Yue Wang, Yanyan Chen, Jingjing Chen, Jiawen Wang, Meichen Liu, Siming Wang. Pueraria protein extract inhibits melanogenesis and promotes melanoma cell apoptosis through the regulation of MITF and mitochondrial‑related pathways. Molecular medicine reports. 2023 Mar; 27(3):. doi: 10.3892/mmr.2023.12951. [PMID: 36734267]
  • Changhai Liu, Mayire Nueraihemaiti, Deng Zang, Salamet Edirs, Guoan Zou, Haji Akber Aisa. Quercetin 3-O-(6″-O-E-caffeoyl)-β-D-glucopyranoside, a Flavonoid Compound, Promotes Melanogenesis through the Upregulation of MAPKs and Akt/GSK3β/β-Catenin Signaling Pathways. International journal of molecular sciences. 2023 Mar; 24(5):. doi: 10.3390/ijms24054780. [PMID: 36902210]
  • Yiming Zhu, Lingtao Duan, Chengqi Zhu, Li Wang, Zhenrui He, Mei Yang, Erxun Zhou. Dual Transcriptome Analysis Reveals That ChATG8 Is Required for Fungal Development, Melanization and Pathogenicity during the Interaction between Colletotrichum higginsianum and Arabidopsis thaliana. International journal of molecular sciences. 2023 Feb; 24(5):. doi: 10.3390/ijms24054376. [PMID: 36901806]
  • Rita Argenziano, Maria Laura Alfieri, Noemi Gallucci, Gerardino D'Errico, Lucia Panzella, Alessandra Napolitano. A Model Eumelanin from 5,6-Dihydroxyindole-2-Carboxybutanamide Combining Remarkable Antioxidant and Photoprotective Properties with a Favourable Solubility Profile for Dermo-Cosmetic Applications. International journal of molecular sciences. 2023 Feb; 24(4):. doi: 10.3390/ijms24044241. [PMID: 36835650]
  • Fan Zhou, Xue-Ying Lu, Fei He, Tao Wu, Haji Akber Aisa, Maitinuer Maiwulanjiang. Effects of traditional artiri La Li formulation on experimental models of vitiligo and mechanisms of melanogenesis. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115884. doi: 10.1016/j.jep.2022.115884. [PMID: 36341815]
  • Junyuan Lv, Shichao Liu, Xiaojian Zhang, Lihong Zhao, Tao Zhang, Zhigang Zhang, Zili Feng, Feng Wei, Jinglong Zhou, Ruiyuan Zhao, Hongjie Feng, Heqin Zhu, Caihong Li, Yalin Zhang. VdERG2 was involved in ergosterol biosynthesis, nutritional differentiation and virulence of Verticillium dahliae. Current genetics. 2023 Feb; 69(1):25-40. doi: 10.1007/s00294-022-01257-9. [PMID: 36416932]
  • Yoko Niki, Naoko Adachi, Masaki Fukata, Yuko Fukata, Shinichiro Oku, Chieko Makino-Okamura, Seiji Takeuchi, Kazumasa Wakamatsu, Shosuke Ito, Lieve Declercq, Daniel B Yarosh, Tomas Mammone, Chikako Nishigori, Naoaki Saito, Takehiko Ueyama. S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis. The Journal of investigative dermatology. 2023 Feb; 143(2):317-327.e6. doi: 10.1016/j.jid.2022.08.040. [PMID: 36063887]
  • In-Hwan Joo, Ji-Hee Choi, Dong-Hee Kim, Moon-Jung Chung, Mi-Hye Lim. Ligularia fischeri ethanol extract: An inhibitor of alpha-melanocyte-stimulating hormone-stimulated melanogenesis in B16F10 melanoma cells. Journal of cosmetic dermatology. 2023 Feb; 22(2):637-644. doi: 10.1111/jocd.15335. [PMID: 36030197]
  • Chien-Shan Chiu, Yu-Tsung Cheng, Yung-Jia Chan, Wen-Chien Lu, Kai-Min Yang, Po- Hsien Li. Mechanism and inhibitory effects of cactus (Opuntia dillenii) extract on melanocytes and its potential application for whitening cosmetics. Scientific reports. 2023 Jan; 13(1):501. doi: 10.1038/s41598-022-26125-x. [PMID: 36627306]
  • Mubashir Hassan, Saba Shahzadi, Andrzej Kloczkowski. Tyrosinase Inhibitors Naturally Present in Plants and Synthetic Modifications of These Natural Products as Anti-Melanogenic Agents: A Review. Molecules (Basel, Switzerland). 2023 Jan; 28(1):. doi: 10.3390/molecules28010378. [PMID: 36615571]
  • Qiao Jin, Yang Wang, Haodong Yin, Haobo Jiang. Two clip-domain serine protease homologs, cSPH35 and cSPH242, act as a cofactor for prophenoloxidase-1 activation in Drosophila melanogaster. Frontiers in immunology. 2023; 14(?):1244792. doi: 10.3389/fimmu.2023.1244792. [PMID: 37781370]
  • Fabio A Zucca, Andrea Capucciati, Chiara Bellei, Michał Sarna, Tadeusz Sarna, Enrico Monzani, Luigi Casella, Luigi Zecca. Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role. IUBMB life. 2023 01; 75(1):55-65. doi: 10.1002/iub.2654. [PMID: 35689524]
  • Ayse Kose. Chemical Composition and Tyrosinase Inhibitory Activities of Fatty Acids Obtained from Heterotrophic Microalgae, S. limacinum and C. cohnii. Applied biochemistry and biotechnology. 2023 Jan; 195(1):369-385. doi: 10.1007/s12010-022-04143-9. [PMID: 36083430]
  • Chen Wang, Jinhui Wang, Dai Zhang, Jianing Cheng, Jiehua Zhu, Zhihui Yang. Identification and functional analysis of protein secreted by Alternaria solani. PloS one. 2023; 18(3):e0281530. doi: 10.1371/journal.pone.0281530. [PMID: 36877688]
  • Ji Hye Yoon, Won Young Jang, Sang Hee Park, Han Gyung Kim, Youn Young Shim, Martin J T Reaney, Jae Youl Cho. Anti-Melanogenesis Effects of a Cyclic Peptide Derived from Flaxseed via Inhibition of CREB Pathway. International journal of molecular sciences. 2022 Dec; 24(1):. doi: 10.3390/ijms24010536. [PMID: 36613979]
  • Sukhbir Singh, Neelam Sharma, Ishrat Zahoor, Tapan Behl, Anita Antil, Sumeet Gupta, Md Khalid Anwer, Syam Mohan, Simona Gabriela Bungau. Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010220. [PMID: 36615414]
  • Jarosław Widelski, Katarzyna Gaweł-Bęben, Karolina Czech, Emil Paluch, Olga Bortkiewicz, Solomiia Kozachok, Tomasz Mroczek, Piotr Okińczyc. Extracts from European Propolises as Potent Tyrosinase Inhibitors. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010055. [PMID: 36615251]
  • Ahmed Ashour, Ahmed Elbermawi, Yhiya Amen, Ahmed E Allam, Hiromi Ikeda, Maki Nagata, Kenta Kumagae, Tomoyo Azuma, Aya Taguchi, Takuya Takemoto, Masako Matsumoto, Kuniyoshi Shimizu. Melanin Synthesis Inhibition Activity of Compounds Isolated from Bamboo Shoot Skin (Phyllostachys pubescens). Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010023. [PMID: 36615219]
  • Anna Gryn-Rynko, Beata Sperkowska, Michał S Majewski. Screening and Structure-Activity Relationship for Selective and Potent Anti-Melanogenesis Agents Derived from Species of Mulberry (Genus Morus). Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27249011. [PMID: 36558142]
  • Michal Styczynski, Agata Rogowska, Christine Nyabayo, Przemyslaw Decewicz, Filip Romaniuk, Cezary Pączkowski, Anna Szakiel, Roderich Suessmuth, Lukasz Dziewit. Heterologous production and characterization of a pyomelanin of Antarctic Pseudomonas sp. ANT_H4: a metabolite protecting against UV and free radicals, interacting with iron from minerals and exhibiting priming properties toward plant hairy roots. Microbial cell factories. 2022 Dec; 21(1):261. doi: 10.1186/s12934-022-01990-3. [PMID: 36527127]
  • Cang Li, Le Kuai, Rutao Cui, Xiao Miao. Melanogenesis and the Targeted Therapy of Melanoma. Biomolecules. 2022 12; 12(12):. doi: 10.3390/biom12121874. [PMID: 36551302]
  • Anna Rassabina, Venera Khabibrakhmanova, Vasily Babaev, Amina Daminova, Farida Minibayeva. Melanins from the Lichens Lobaria pulmonaria and Lobaria retigera as Eco-Friendly Adsorbents of Synthetic Dyes. International journal of molecular sciences. 2022 Dec; 23(24):. doi: 10.3390/ijms232415605. [PMID: 36555244]
  • Eka Sunarwidhi Prasedya, Hasriaton Padmi, Bq Tri Khairina Ilhami, Ni Wayan Riyani Martyasari, Anggit Listyacahyani Sunarwidhi, Sri Widyastuti, Miski Aghnia Khairinisa, Nunik Cokrowati, Erika Ernawati Simangunsong, Andri Frediansyah. Brown Macroalgae Sargassum cristaefolium Extract Inhibits Melanin Production and Cellular Oxygen Stress in B16F10 Melanoma Cells. Molecules (Basel, Switzerland). 2022 Dec; 27(23):. doi: 10.3390/molecules27238585. [PMID: 36500679]
  • Huilin Yu, Wantong Jia, Meixi Zhao, Le Li, Jinliang Liu, Jingyuan Chen, Hongyu Pan, Xianghui Zhang. Antifungal mechanism of isothiocyanates against Cochliobolus heterostrophus. Pest management science. 2022 Dec; 78(12):5133-5141. doi: 10.1002/ps.7131. [PMID: 36053944]
  • Jingpei Shi, Yanfang Guo, Hanying Wang, Yun Xiao, Weimin Liu, Lechun Lyu. The ubiquitin-proteasome system in melanin metabolism. Journal of cosmetic dermatology. 2022 Dec; 21(12):6661-6668. doi: 10.1111/jocd.15433. [PMID: 36207998]
  • Palwasha Khan, Naveed Akhtar, Haji Muhammad Shoaib Khan, Rabia Tasneem, Hafiz Saqib Zaka, Naheed Akhtar, Arfa Sharif. Assessment of Brassica oleraceae L. (Brassicaceae) extract loaded ethosomal gel as a versatile vesicular carrier system for dermocosmetic application: A noninvasive split-faced study. Journal of cosmetic dermatology. 2022 Dec; 21(12):7153-7162. doi: 10.1111/jocd.15436. [PMID: 36204972]
  • Duc Dat Le, Ye Eun Lee, Mina Lee. Triterpenoids from the leaves of Osmanthus fragrans var. aurantiacus with their anti-melanogenesis and anti-tyrosinase activities. Natural product research. 2022 Dec; 36(24):6414-6420. doi: 10.1080/14786419.2022.2035384. [PMID: 35133178]
  • Danni Feng, Zhongxiang Fang, Pangzhen Zhang. The melanin inhibitory effect of plants and phytochemicals: A systematic review. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Dec; 107(?):154449. doi: 10.1016/j.phymed.2022.154449. [PMID: 36126406]
  • Wei Zhao, Anquan Yang, Jing Wang, Dan Huang, Yankang Deng, Xiaoli Zhang, Qingli Qu, Wenjing Ma, Ranhua Xiong, Miaomiao Zhu, Chaobo Huang. Potential application of natural bioactive compounds as skin-whitening agents: A review. Journal of cosmetic dermatology. 2022 Dec; 21(12):6669-6687. doi: 10.1111/jocd.15437. [PMID: 36204978]
  • Su-Jin Lim, Da-Won Jung, Prima F Hillman, Sang-Jip Nam, Chang-Seok Lee. SNA077, an Extract of Marine Streptomyces sp., Inhibits Melanogenesis by Downregulating Melanogenic Proteins via Inactivation of cAMP/PKA/CREB Signaling. International journal of molecular sciences. 2022 Nov; 23(23):. doi: 10.3390/ijms232314922. [PMID: 36499251]
  • Anna Merecz-Sadowska, Przemysław Sitarek, Joanna Stelmach, Karolina Zajdel, Ewa Kucharska, Radosław Zajdel. Plants as Modulators of Melanogenesis: Role of Extracts, Pure Compounds and Patented Compositions in Therapy of Pigmentation Disorders. International journal of molecular sciences. 2022 Nov; 23(23):. doi: 10.3390/ijms232314787. [PMID: 36499134]
  • Jun-Fang Wu, Ablajan Turak, Deng Zang, Guo-An Zou, Haji Akber Aisa. Sesquiterpenoids from Seriphidium transiliense and Their Melanogenic Activity. Journal of natural products. 2022 11; 85(11):2570-2582. doi: 10.1021/acs.jnatprod.2c00527. [PMID: 36326734]
  • Tao Liu, Jun Qin, Yonghong Cao, Krishna V Subbarao, Jieyin Chen, Mihir K Mandal, Xiangming Xu, Wenjing Shang, Xiaoping Hu. Transcription Factor VdCf2 Regulates Growth, Pathogenicity, and the Expression of a Putative Secondary Metabolism Gene Cluster in Verticillium dahliae. Applied and environmental microbiology. 2022 11; 88(22):e0138522. doi: 10.1128/aem.01385-22. [PMID: 36342142]
  • J Yang, X Chen. [Natural melanin-based nanoparticles with photothermal/photodynamic activities induce ovarian cancer cell death]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2022 Nov; 42(11):1681-1688. doi: 10.12122/j.issn.1673-4254.2022.11.12. [PMID: 36504061]
  • Deng Zang, Chao Niu, Xueying Lu, Haji Akber Aisa. A Novel Furocoumarin Derivative, 5-((diethylamino)me-13 thyl)-3-phenyl-7H-furo [3,2-g] chromen-7-one Upregulates Melanin Synthesis via the Activation of cAMP/PKA and MAPKs Signal Pathway: In Vitro and In Vivo Study. International journal of molecular sciences. 2022 Nov; 23(22):. doi: 10.3390/ijms232214190. [PMID: 36430668]
  • Leon Valentin Bork, Sascha Rohn, Clemens Kanzler. Characterization of Colorants Formed by Non-Enzymatic Browning Reactions of Hydroxycinnamic Acid Derivatives. Molecules (Basel, Switzerland). 2022 Nov; 27(21):. doi: 10.3390/molecules27217564. [PMID: 36364391]
  • Patrícia Matos, António Paranhos, Maria Teresa Batista, Artur Figueirinha. Synergistic Effect of DIBOA and Verbascoside from Acanthus mollis Leaf on Tyrosinase Inhibition. International journal of molecular sciences. 2022 Nov; 23(21):. doi: 10.3390/ijms232113536. [PMID: 36362321]
  • Jun Gu Kim, Thi Phuong Linh Le, Jae Sang Han, Yong Beom Cho, Haeun Kwon, Dongho Lee, Mi Kyeong Lee, Bang Yeon Hwang. Bioactive molecular network-guided discovery of dihydro-β-agarofurans from the fruits of Celastrus orbiculatus. Phytochemistry. 2022 Nov; 203(?):113349. doi: 10.1016/j.phytochem.2022.113349. [PMID: 35973614]
  • Odile Francesca Restaino, Monica Scognamiglio, S Fatemeh Mirpoor, Marcella Cammarota, Riccardo Ventriglia, C Valeria L Giosafatto, Antonio Fiorentino, Raffaele Porta, Chiara Schiraldi. Enhanced Streptomyces roseochromogenes melanin production by using the marine renewable source Posidonia oceanica egagropili. Applied microbiology and biotechnology. 2022 Nov; 106(21):7265-7283. doi: 10.1007/s00253-022-12191-8. [PMID: 36198867]
  • Delong Wang, Min Li, Chunxia Yuan, Yali Fang, Zhijia Zhang. Guaiacol as a natural melanin biosynthesis inhibitor to control northern corn leaf blight. Pest management science. 2022 Nov; 78(11):4557-4568. doi: 10.1002/ps.7075. [PMID: 35833811]
  • Bei Bei Zhou, Dan Liu, Jia Cheng Qian, Ren Xiang Tan. Vegetable-derived indole enhances the melanoma-treating efficacy of chemotherapeutics. Phytotherapy research : PTR. 2022 Nov; 36(11):4278-4292. doi: 10.1002/ptr.7565. [PMID: 35883268]
  • Myra O Villareal, Thanyanan Chaochaiphat, Rachida Makbal, Chemseddoha Gadhi, Hiroko Isoda. Molecular Analysis of the Melanogenesis Inhibitory Effect of Saponins-Rich Fraction of Argania spinosa Leaves Extract. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196762. [PMID: 36235295]
  • Litao Niu, Nigora Rustamova, Huxia Ning, Paiziliya Paerhati, Chunfang Lu, Abulimiti Yili. Diversity and Biological Activities of Endophytic Fungi from the Flowers of the Medicinal Plant Vernonia anthelmintica. International journal of molecular sciences. 2022 Oct; 23(19):. doi: 10.3390/ijms231911935. [PMID: 36233244]
  • Wenkui Liu, Lu Han, Jinzhu Chen, Xiaofei Liang, Bo Wang, Mark L Gleason, Rong Zhang, Guangyu Sun. The CfMcm1 Regulates Pathogenicity, Conidium Germination, and Sexual Development in Colletotrichum fructicola. Phytopathology. 2022 Oct; 112(10):2159-2173. doi: 10.1094/phyto-03-22-0090-r. [PMID: 35502927]
  • Qianqian Jiang, Renyan Mao, Yongcai Li, Yang Bi, Yongxiang Liu, Miao Zhang, Rong Li, Yangyang Yang, Dov B Prusky. AaCaM is required for infection structure differentiation and secondary metabolites in pear fungal pathogen Alternaria alternata. Journal of applied microbiology. 2022 Oct; 133(4):2631-2641. doi: 10.1111/jam.15732. [PMID: 35870147]
  • Xiaofei Liang, Bingxuan Li, Xuemei Zhao, Liqiang Yao, Yuanyuan Kong, Wenkui Liu, Rong Zhang, Guangyu Sun. 1,8-Dihydroxynaphthalene Melanin Biosynthesis in Colletotrichum fructicola Is Developmentally Regulated and Requires the Cooperative Function of Two Putative Zinc Finger Transcription Factors. Phytopathology. 2022 Oct; 112(10):2174-2186. doi: 10.1094/phyto-01-22-0037-r. [PMID: 36154270]
  • Kenchi Miyasaka, Yoshiaki Manse, Akari Yoneda, Shogo Takeda, Norihito Shimizu, Wakana Yamada, Toshio Morikawa, Hiroshi Shimoda. Anti-melanogenic effects of glucosylceramides and elasticamide derived from rice oil by-products in melanoma cells, melanocytes, and human skin. Journal of food biochemistry. 2022 10; 46(10):e14353. doi: 10.1111/jfbc.14353. [PMID: 35986572]