L-2,3-Dihydrodipicolinate (BioDeep_00000005178)

 

Secondary id: BioDeep_00001870074

human metabolite Endogenous


代谢物信息卡片


2,3-dihydropyridine-2,6-dicarboxylic acid

化学式: C7H7NO4 (169.0375)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(not specific) 5.71%

分子结构信息

SMILES: C1C=CC(=NC1C(=O)O)C(=O)O
InChI: InChI=1S/C7H7NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-2,5H,3H2,(H,9,10)(H,11,12)

描述信息

L-2,3-Dihydrodipicolinate is involved in the lysine biosynthesis I pathway. L-2,3-Dihydrodipicolinate is produced from a reaction between pyruvate and L-aspartate-semialdehyde, with water as a byproduct. The reaction is catalyzed by dihydrodipicolinate synthase. L-2,3-dihydrodipicolinate reacts with NAD(P)H and H+ to produce tetrahydrodipicolinate and NAD(P)+. The reaction is catalyzed by dihydrodipicolinate reductase.
L-2,3-Dihydrodipicolinate is involved in the lysine biosynthesis I pathway. L-2,3-Dihydrodipicolinate is produced from a reaction between pyruvate and L-aspartate-semialdehyde, with water as a byproduct. The reaction is catalyzed by dihydrodipicolinate synthase.

同义名列表

9 个代谢物同义名

2,3-dihydropyridine-2,6-dicarboxylic acid; (S)-2,3-Dihydrodipicolinic acid; L-2,3-Dihydrodipicolinic acid; 2,3-dihydrodipicolinic acid; L-2,3-Dihydrodipicolinate; 2,3-Dihydrodipicolinate; Dihydrodipicolinic acid; 2,3-Di-H-dipicolinate; Dihydrodipicolinate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

494 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(492)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lu Zhang, Qingzhong Wang, Wenjie Wang, Yanyan Liu, Jie Wang, Jun Yue, Ying Xu, Wenxi Xu, Zhenling Cui, Xuelian Zhang, Honghai Wang. Identification of putative biomarkers for the serodiagnosis of drug-resistant Mycobacterium tuberculosis. Proteome science. 2012 Feb; 10(?):12. doi: 10.1186/1477-5956-10-12. [PMID: 22364187]
  • Michael D W Griffin, Jagan M Billakanti, Akshita Wason, Sabrina Keller, Haydyn D T Mertens, Sarah C Atkinson, Renwick C J Dobson, Matthew A Perugini, Juliet A Gerrard, Frederick Grant Pearce. Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana. PloS one. 2012; 7(7):e40318. doi: 10.1371/journal.pone.0040318. [PMID: 22792278]
  • Giuseppe Dionisio, Claus K Madsen, Preben B Holm, Karen G Welinder, Malene Jørgensen, Eva Stoger, Elsa Arcalis, Henrik Brinch-Pedersen. Cloning and characterization of purple acid phosphatase phytases from wheat, barley, maize, and rice. Plant physiology. 2011 Jul; 156(3):1087-100. doi: 10.1104/pp.110.164756. [PMID: 21220762]
  • B P Mallikarjuna Swamy, Prashant Vikram, Shalabh Dixit, H U Ahmed, Arvind Kumar. Meta-analysis of grain yield QTL identified during agricultural drought in grasses showed consensus. BMC genomics. 2011 Jun; 12(?):319. doi: 10.1186/1471-2164-12-319. [PMID: 21679437]
  • Travis J Riedel, Lynnette C Johnson, John Knight, Roy R Hantgan, Ross P Holmes, W Todd Lowther. Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. PloS one. 2011; 6(10):e26021. doi: 10.1371/journal.pone.0026021. [PMID: 21998747]
  • Renwick C J Dobson, Irma Girón, André O Hudson. L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. PloS one. 2011; 6(5):e20439. doi: 10.1371/journal.pone.0020439. [PMID: 21633707]
  • Zhongsen Li, Bryan P Moon, Aiqiu Xing, Zhan-Bin Liu, Richard P McCardell, Howard G Damude, S Carl Falco. Stacking multiple transgenes at a selected genomic site via repeated recombinase-mediated DNA cassette exchanges. Plant physiology. 2010 Oct; 154(2):622-31. doi: 10.1104/pp.110.160093. [PMID: 20720171]
  • Kim H Hebelstrup, Michael W Christiansen, Massimiliano Carciofi, Birgitte Tauris, Henrik Brinch-Pedersen, Preben B Holm. UCE: A uracil excision (USER)-based toolbox for transformation of cereals. Plant methods. 2010 Jun; 6(?):15. doi: 10.1186/1746-4811-6-15. [PMID: 20537147]
  • Cristina Viadas, María C Rodríguez, Felix J Sangari, Jean-Pierre Gorvel, Juan M García-Lobo, Ignacio López-Goñi. Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system. PloS one. 2010 Apr; 5(4):e10216. doi: 10.1371/journal.pone.0010216. [PMID: 20422049]
  • Suryadevara S Rao, Lewamy Mamadou, Matt McConnell, Raghuveer Polisetty, Prachuab Kwanyuen, David Hildebrand. Non-antibiotic selection systems for soybean somatic embryos: the lysine analog aminoethyl-cysteine as a selection agent. BMC biotechnology. 2009 Nov; 9(?):94. doi: 10.1186/1472-6750-9-94. [PMID: 19922622]
  • Ying-Tsong Chen, Tsai-Lien Liao, Keh-Ming Wu, Tsai-Ling Lauderdale, Jing-Jou Yan, I-Wen Huang, Min-Chi Lu, Yi-Chyi Lai, Yen-Ming Liu, Hung-Yu Shu, Jin-Town Wang, Ih-Jen Su, Shih-Feng Tsai. Genomic diversity of citrate fermentation in Klebsiella pneumoniae. BMC microbiology. 2009 Aug; 9(?):168. doi: 10.1186/1471-2180-9-168. [PMID: 19682387]
  • Zhenyu Cheng, Yi-Yun C Wei, Wilson W L Sung, Bernard R Glick, Brendan J McConkey. Proteomic analysis of the response of the plant growth-promoting bacterium Pseudomonas putida UW4 to nickel stress. Proteome science. 2009 May; 7(?):18. doi: 10.1186/1477-5956-7-18. [PMID: 19422705]
  • M Dudley Page, Janette Kropat, Patrice P Hamel, Sabeeha S Merchant. Two Chlamydomonas CTR copper transporters with a novel cys-met motif are localized to the plasma membrane and function in copper assimilation. The Plant cell. 2009 Mar; 21(3):928-43. doi: 10.1105/tpc.108.064907. [PMID: 19318609]
  • Gilles Curien, Olivier Bastien, Mylène Robert-Genthon, Athel Cornish-Bowden, María Luz Cárdenas, Renaud Dumas. Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters. Molecular systems biology. 2009; 5(?):271. doi: 10.1038/msb.2009.29. [PMID: 19455135]
  • Jinling Huang, J Peter Gogarten. Concerted gene recruitment in early plant evolution. Genome biology. 2008; 9(7):R109. doi: 10.1186/gb-2008-9-7-r109. [PMID: 18611267]
  • Hideyuki Shimizu, Toshiharu Shikanai. Dihydrodipicolinate reductase-like protein, CRR1, is essential for chloroplast NAD(P)H dehydrogenase in Arabidopsis. The Plant journal : for cell and molecular biology. 2007 Nov; 52(3):539-47. doi: 10.1111/j.1365-313x.2007.03256.x. [PMID: 17727612]
  • Andre' O Hudson, Christine Bless, Polliana Macedo, Siba P Chatterjee, Bijay K Singh, Charles Gilvarg, Thomas Leustek. Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways. Biochimica et biophysica acta. 2005 Jan; 1721(1-3):27-36. doi: 10.1016/j.bbagen.2004.09.008. [PMID: 15652176]