L-histidinol-phosphate (BioDeep_00000004572)

 

Secondary id: BioDeep_00001869534

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER

化学式: C6H12N3O4P (221.05654019999997)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 0.12%

分子结构信息

SMILES: C1=C(NC=N1)CC(COP(=O)(O)O)N
InChI: InChI=1S/C6H12N3O4P/c7-5(3-13-14(10,11)12)1-6-2-8-4-9-6/h2,4-5H,1,3,7H2,(H,8,9)(H2,10,11,12)/t5-/m0/s1

描述信息

L-histidinol-phosphate is a member of the class of compounds known as phosphoethanolamines. Phosphoethanolamines are compounds containing a phosphate linked to the second carbon of an ethanolamine. L-histidinol-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). L-histidinol-phosphate can be found in a number of food items such as sorghum, devilfish, spearmint, and deerberry, which makes L-histidinol-phosphate a potential biomarker for the consumption of these food products. L-histidinol-phosphate exists in E.coli (prokaryote) and yeast (eukaryote).

同义名列表

7 个代谢物同义名

PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER; PHOSPHate mono-[2-amino-3-(3H-imidazol-4-yl)-propyl]ester; [(2S)-2-amino-3-(1H-imidazol-4-yl)propoxy]phosphonic acid; L-Histidinol phosphoric acid; L-Histidinol-phosphoric acid; L-histidinol phosphate; L-histidinol-phosphate



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

311 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(1)

Plant Reactome(308)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • R L M Guedes, F Prosdocimi, G R Fernandes, L K Moura, H A L Ribeiro, J M Ortega. Amino acids biosynthesis and nitrogen assimilation pathways: a great genomic deletion during eukaryotes evolution. BMC genomics. 2011 Dec; 12 Suppl 4(?):S2. doi: 10.1186/1471-2164-12-s4-s2. [PMID: 22369087]
  • Minjie Wang, Zhenhua Han, Zhen Wu, Yuqiang Zhao, Dujuan Gao, Jianchao Wang, Guoliang Qian, Baishi Hu. [Relationship of histidine auxotrophy of Acidovorax citrulli with pathogenicity]. Wei sheng wu xue bao = Acta microbiologica Sinica. 2011 Sep; 51(9):1185-93. doi: ". [PMID: 22126073]
  • Osbaldo Resendis-Antonio, Magdalena Hernández, Emmanuel Salazar, Sandra Contreras, Gabriel Martínez Batallar, Yolanda Mora, Sergio Encarnación. Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling. BMC systems biology. 2011 Jul; 5(?):120. doi: 10.1186/1752-0509-5-120. [PMID: 21801415]
  • Rayko Becher, Fabian Weihmann, Holger B Deising, Stefan Gr Wirsel. Development of a novel multiplex DNA microarray for Fusarium graminearum and analysis of azole fungicide responses. BMC genomics. 2011 Jan; 12(?):52. doi: 10.1186/1471-2164-12-52. [PMID: 21255412]
  • Mingjun Li, Fengwang Ma, Dong Liang, Juan Li, Yanlei Wang. Ascorbate biosynthesis during early fruit development is the main reason for its accumulation in kiwi. PloS one. 2010 Dec; 5(12):e14281. doi: 10.1371/journal.pone.0014281. [PMID: 21151561]
  • Shih-Chi Hsu, Mark F Belmonte, John J Harada, Kentaro Inoue. Indispensable Roles of Plastids in Arabidopsis thaliana Embryogenesis. Current genomics. 2010 Aug; 11(5):338-49. doi: 10.2174/138920210791616716. [PMID: 21286311]
  • Lindsay N Petersen, Sandra Marineo, Salvatore Mandalà, Faezah Davids, Bryan T Sewell, Robert A Ingle. The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase. Plant physiology. 2010 Mar; 152(3):1186-96. doi: 10.1104/pp.109.150805. [PMID: 20023146]
  • Liangbing Wang, Hua Huang, Henry H Nguyen, Karen N Allen, Patrick S Mariano, Debra Dunaway-Mariano. Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB). Biochemistry. 2010 Feb; 49(6):1072-81. doi: 10.1021/bi902018y. [PMID: 20050615]
  • Pranav R Prabhu, André O Hudson. Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana. Biochemistry research international. 2010; 2010(?):549572. doi: 10.1155/2010/549572. [PMID: 21188077]
  • David Bikard, Dhaval Patel, Claire Le Metté, Veronica Giorgi, Christine Camilleri, Malcolm J Bennett, Olivier Loudet. Divergent evolution of duplicate genes leads to genetic incompatibilities within A. thaliana. Science (New York, N.Y.). 2009 Jan; 323(5914):623-6. doi: 10.1126/science.1165917. [PMID: 19179528]
  • I El-Sharkawy, W S Kim, S Jayasankar, A M Svircev, D C W Brown. Differential regulation of four members of the ACC synthase gene family in plum. Journal of experimental botany. 2008; 59(8):2009-27. doi: 10.1093/jxb/ern056. [PMID: 18535295]
  • Xiaorong Mo, Qingyu Zhu, Xiang Li, Jing Li, Qingning Zeng, Honglin Rong, Hanma Zhang, Ping Wu. The hpa1 mutant of Arabidopsis reveals a crucial role of histidine homeostasis in root meristem maintenance. Plant physiology. 2006 Aug; 141(4):1425-35. doi: 10.1104/pp.106.084178. [PMID: 16815950]
  • Géraldine Nollevaux, Christelle Devillé, Benaïssa El Moualij, Willy Zorzi, Patricia Deloyer, Yves-Jacques Schneider, Olivier Peulen, Guy Dandrifosse. Development of a serum-free co-culture of human intestinal epithelium cell-lines (Caco-2/HT29-5M21). BMC cell biology. 2006 May; 7(?):20. doi: 10.1186/1471-2121-7-20. [PMID: 16670004]
  • Giles C Shih, Charlene M Kahler, Russell W Carlson, M Mahbubur Rahman, David S Stephens. gmhX, a novel gene required for the incorporation of L-glycero-D-manno-heptose into lipooligosaccharide in Neisseria meningitidis. Microbiology (Reading, England). 2001 Aug; 147(Pt 8):2367-2377. doi: 10.1099/00221287-147-8-2367. [PMID: 11496013]
  • F El Malki, M Jacobs. Molecular characterization and expression study of a histidine auxotrophic mutant (his1-) of Nicotiana plumbaginifolia. Plant molecular biology. 2001 Jan; 45(2):191-9. doi: 10.1023/a:1006493021557. [PMID: 11289510]
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