L-2-Amino-4-methylenepentanedioic acid (BioDeep_00000004460)

 

Secondary id: BioDeep_00001869659

human metabolite Endogenous


代谢物信息卡片


4-Methyleneglutamic acid, sodium salt, (L-glu)-isomer

化学式: C6H9NO4 (159.0532)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(otcml) 17.52%

分子结构信息

SMILES: C=C(CC(C(=O)O)N)C(=O)O
InChI: InChI=1S/C6H9NO4/c1-3(5(8)9)2-4(7)6(10)11/h4H,1-2,7H2,(H,8,9)(H,10,11)

描述信息

L-2-Amino-4-methylenepentanedioic acid is found in alcoholic beverages. L-2-Amino-4-methylenepentanedioic acid is a constituent of peanuts (Arachis hypogaea) and other plants, notably tulips and hops

同义名列表

21 个代谢物同义名

4-Methyleneglutamic acid, sodium salt, (L-glu)-isomer; (2S,3R)-(2,3-2H2)-4-Methyleneglutamic acid; (2S,3S)-(3-2H1)-4-Methyleneglutamic acid; 4-Methyleneglutamic acid, (L-glu)-isomer; L-2-Amino-4-methylenepentanedioic acid; 2-amino-4-methylidenepentanedioic acid; L-2-Amino-4-methylenepentanedioate; gamma-Methylene glutamic acid; 4-Methylene-DL-glutamic acid; 4-Methylidene glutamic acid; 4-Methylene-L-glutamic acid; gamma-Methylene glutamate; 4-Methylene glutamic acid; Γ-methylene glutamic acid; g-Methylene glutamic acid; 4-Methyleneglutamic acid; 4-Methylene-DL-glutamate; 4-Methylene-L-glutamate; Γ-methylene glutamate; g-Methylene glutamate; 4-Methyleneglutamate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • S R Baker, D Bleakman, J Ezquerra, B A Ballyk, M Deverill, K Ho, R K Kamboj, I Collado, C Domínguez, A Escribano, A I Mateo, C Pedregal, A Rubio. 4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists. Bioorganic & medicinal chemistry letters. 2000 Aug; 10(16):1807-10. doi: 10.1016/s0960-894x(00)00346-2. [PMID: 10969973]
  • H C Winter, T Ueda. Glutamate uptake system in the presynaptic vesicle: glutamic acid analogs as inhibitors and alternate substrates. Neurochemical research. 1993 Jan; 18(1):79-85. doi: 10.1007/bf00966925. [PMID: 8096630]
  • R P Simondsen, A Meister. Interaction of the D-isomer of gamma-methylene glutamate with an active site thiol of gamma-glutamylcysteine synthetase. The Journal of biological chemistry. 1986 Dec; 261(36):17134-7. doi: NULL. [PMID: 2877992]
  • S F Wright, C D Bourne, R A Hoke, K A Koehler, R G Hiskey. A method for specific chemical modification of gamma-carboxyglutamic acid residues in proteins. Analytical biochemistry. 1984 May; 139(1):82-90. doi: 10.1016/0003-2697(84)90392-0. [PMID: 6547575]
  • J DONE, L FOWDEN. A new amino acid amide in the groundnut plant (Arachis hypogaea); evidence of the occurrence of gamma-methyleneglutamine and gamma-methyleneglutamic acid. The Biochemical journal. 1952 Jul; 51(4):451-8. doi: 10.1042/bj0510451. [PMID: 13018102]