3,5-DIHYDROXYBENZOIC ACID (BioDeep_00000416041)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3,5-DIHYDROXYBENZOIC ACID

化学式: C7H6O4 (154.0266076)
中文名称: 3,5-二羟基苯甲酸
谱图信息: 最多检出来源 Viridiplantae(plant) 90%

分子结构信息

SMILES: C1=C(C=C(C=C1O)O)C(=O)O
InChI: InChI=1S/C7H6O4/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,8-9H,(H,10,11)

描述信息

A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 5.
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.
3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.

同义名列表

1 个代谢物同义名

3,5-DIHYDROXYBENZOIC ACID



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

41 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Muhammad Ichwan, Tara L Walker, Zeina Nicola, Jutta Ludwig-Müller, Christoph Böttcher, Rupert W Overall, Vijay S Adusumilli, Merve Bulut, Alex M Sykes, Norbert Hübner, Gerardo Ramirez-Rodriguez, Leonardo Ortiz-López, Enrique A Lugo-Hernández, Gerd Kempermann. Apple Peel and Flesh Contain Pro-neurogenic Compounds. Stem cell reports. 2021 03; 16(3):548-565. doi: 10.1016/j.stemcr.2021.01.005. [PMID: 33577796]
  • Przemysław Sitarek, Ewa Skała, Monika Toma, Marzena Wielanek, Janusz Szemraj, Tomasz Skorski, Adam J Białas, Tomasz Sakowicz, Tomasz Kowalczyk, Maciej Radek, Halina Wysokińska, Tomasz Śliwiński. Transformed Root Extract of Leonurus sibiricus Induces Apoptosis through Intrinsic and Extrinsic Pathways in Various Grades of Human Glioma Cells. Pathology oncology research : POR. 2017 Jul; 23(3):679-687. doi: 10.1007/s12253-016-0170-6. [PMID: 28032310]
  • Roksana Wierzbicka, Galia Zamaratskaia, Afaf Kamal-Eldin, Rikard Landberg. Novel urinary alkylresorcinol metabolites as biomarkers of whole grain intake in free-living Swedish adults. Molecular nutrition & food research. 2017 07; 61(7):. doi: 10.1002/mnfr.201700015. [PMID: 28444884]
  • Ayşe Baldemir, Neslihan Gökşen, Nilay Ildız, Gökçe Şeker Karatoprak, Müberra Koşar. Phytochemical Profile and Biological Activities of Helianthemum canum l. baumg. from Turkey. Chemistry & biodiversity. 2017 Jul; 14(7):. doi: 10.1002/cbdv.201700052. [PMID: 28306206]
  • Nicola M McKeown, Matti Marklund, Jiantao Ma, Alastair B Ross, Alice H Lichtenstein, Kara A Livingston, Paul F Jacques, Helen M Rasmussen, Jeffrey B Blumberg, C-Y Oliver Chen. Comparison of plasma alkylresorcinols (AR) and urinary AR metabolites as biomarkers of compliance in a short-term, whole-grain intervention study. European journal of nutrition. 2016 Apr; 55(3):1235-44. doi: 10.1007/s00394-015-0936-8. [PMID: 26043861]
  • Laila Meija, Indriķis Krams, Vinita Cauce, Adile Samaletdin, Paivi Söderholm, Raimonds Meija, Līga Lārmane, Aivars Lejnieks, Vilnis Lietuvietis, Herman Adlercreutz. Alkylresorcinol metabolites in urine and plasma as potential biomarkers of rye and wheat fiber consumption in prostate cancer patients and controls. Nutrition and cancer. 2015; 67(2):258-65. doi: 10.1080/01635581.2015.989371. [PMID: 25608053]
  • Matti Marklund, Eric A Strömberg, Helle N Lærke, Knud E Bach Knudsen, Afaf Kamal-Eldin, Andrew C Hooker, Rikard Landberg. Simultaneous pharmacokinetic modeling of alkylresorcinols and their main metabolites indicates dual absorption mechanisms and enterohepatic elimination in humans. The Journal of nutrition. 2014 Nov; 144(11):1674-80. doi: 10.3945/jn.114.196220. [PMID: 25332465]
  • R Wierzbicka, L Eyer, R Landberg, A Kamal-Eldin, M Franek. Development of antibodies for determination of alkylresorcinol metabolites in human urine and elucidation of ELISA cross-reactivity. Journal of immunological methods. 2014 Nov; 413(?):12-24. doi: 10.1016/j.jim.2014.07.007. [PMID: 25066633]
  • Yingdong Zhu, Kelly L Shurlknight, Xiaoxin Chen, Shengmin Sang. Identification and pharmacokinetics of novel alkylresorcinol metabolites in human urine, new candidate biomarkers for whole-grain wheat and rye intake. The Journal of nutrition. 2014 Feb; 144(2):114-22. doi: 10.3945/jn.113.184663. [PMID: 24259554]
  • Matti Marklund, Eric A Strömberg, Andrew C Hooker, Margareta Hammarlund-Udenaes, Per Aman, Rikard Landberg, Afaf Kamal-Eldin. Chain length of dietary alkylresorcinols affects their in vivo elimination kinetics in rats. The Journal of nutrition. 2013 Oct; 143(10):1573-8. doi: 10.3945/jn.113.178392. [PMID: 23946349]
  • J Montonen, R Landberg, A Kamal-Eldin, P Åman, H Boeing, A Steffen, T Pischon. Reliability of fasting plasma alkylresorcinol metabolites concentrations measured 4 months apart. European journal of clinical nutrition. 2012 Aug; 66(8):968-70. doi: 10.1038/ejcn.2012.66. [PMID: 22713774]
  • Alastair B Ross. Present status and perspectives on the use of alkylresorcinols as biomarkers of wholegrain wheat and rye intake. Journal of nutrition and metabolism. 2012; 2012(?):462967. doi: 10.1155/2012/462967. [PMID: 22363838]
  • Päivi P Söderholm, Johan E Lundin, Anja H Koskela, Matti J Tikkanen, Herman C Adlercreutz. Pharmacokinetics of alkylresorcinol metabolites in human urine. The British journal of nutrition. 2011 Oct; 106(7):1040-4. doi: 10.1017/s0007114511001383. [PMID: 21481288]
  • Matti Marklund, Rikard Landberg, Per Åman, Afaf Kamal-Eldin. Comparison of gas chromatography-mass spectrometry and high-performance liquid chromatography with coulometric electrode array detection for determination of alkylresorcinol metabolites in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Mar; 879(9-10):647-51. doi: 10.1016/j.jchromb.2011.01.034. [PMID: 21334988]
  • Susana Tárraga, Purificación Lisón, María Pilar López-Gresa, Cristina Torres, Ismael Rodrigo, José María Bellés, Vicente Conejero. Molecular cloning and characterization of a novel tomato xylosyltransferase specific for gentisic acid. Journal of experimental botany. 2010 Oct; 61(15):4325-38. doi: 10.1093/jxb/erq234. [PMID: 20729481]
  • Takeshi Ishii, Taiki Mori, Tatsuya Ichikawa, Maiko Kaku, Koji Kusaka, Yoshinori Uekusa, Mitsugu Akagawa, Yoshiyuki Aihara, Takumi Furuta, Toshiyuki Wakimoto, Toshiyuki Kan, Tsutomu Nakayama. Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin. Bioorganic & medicinal chemistry. 2010 Jul; 18(14):4892-6. doi: 10.1016/j.bmc.2010.06.021. [PMID: 20598557]
  • Matti Marklund, Rikard Landberg, Per Aman, Afaf Kamal-Eldin. Determination of alkylresorcinol metabolites in human urine by gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Apr; 878(11-12):888-94. doi: 10.1016/j.jchromb.2010.02.007. [PMID: 20223713]
  • Nighat Sultana, Musarrat Akhter, Zakia Khatoon. Nematicidal natural products from the aerial parts of Rubus niveus. Natural product research. 2010 Mar; 24(5):407-15. doi: 10.1080/14786410802696429. [PMID: 20306362]
  • Mylène Aubertin-Leheudre, Anja Koskela, Adile Samaletdin, Herman Adlercreutz. Plasma alkylresorcinol metabolites as potential biomarkers of whole-grain wheat and rye cereal fibre intakes in women. The British journal of nutrition. 2010 Feb; 103(3):339-43. doi: 10.1017/s0007114509992315. [PMID: 19874633]
  • Mylène Aubertin-Leheudre, Anja Koskela, Adile Samaletdin, Herman Adlercreutz. Plasma and urinary alkylresorcinol metabolites as potential biomarkers of breast cancer risk in Finnish women: a pilot study. Nutrition and cancer. 2010; 62(6):759-64. doi: 10.1080/01635581003693058. [PMID: 20661824]
  • Anja Koskela, Adile Samaletdin, Mylène Aubertin-Leheudre, Herman Adlercreutz. Quantification of alkylresorcinol metabolites in plasma by high-performance liquid chromatography with coulometric electrode array detection. Journal of agricultural and food chemistry. 2008 Sep; 56(17):7678-81. doi: 10.1021/jf801252s. [PMID: 18690683]
  • Mylène Aubertin-Leheudre, Anja Koskela, Annukka Marjamaa, Herman Adlercreutz. Plasma alkylresorcinols and urinary alkylresorcinol metabolites as biomarkers of cereal fiber intake in Finnish women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2008 Sep; 17(9):2244-8. doi: 10.1158/1055-9965.epi-08-0215. [PMID: 18768490]
  • Wendy R Russell, Lorraine Scobbie, Garry G Duthie, Andrew Chesson. Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids. Bioorganic & medicinal chemistry. 2008 Apr; 16(8):4589-93. doi: 10.1016/j.bmc.2008.02.041. [PMID: 18314336]
  • Anja Koskela, Anna-Maria Linko-Parvinen, Perttu Hiisivuori, Adile Samaletdin, Afaf Kamal-Eldin, Matti J Tikkanen, Herman Adlercreutz. Quantification of alkylresorcinol metabolites in urine by HPLC with coulometric electrode array detection. Clinical chemistry. 2007 Jul; 53(7):1380-3. doi: 10.1373/clinchem.2006.084764. [PMID: 17495018]
  • Alastair B Ross, Per Aman, Afaf Kamal-Eldin. Identification of cereal alkylresorcinol metabolites in human urine-potential biomarkers of wholegrain wheat and rye intake. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Sep; 809(1):125-30. doi: 10.1016/j.jchromb.2004.06.015. [PMID: 15282102]
  • M Sakurai, M Ohsako, M Nagano, C Nakamura, O Tsuzuki, M Ichikawa, Y Matsumoto. [Effect of human serum albumin on transport of drugs through human erythrocyte membranes]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1996 Aug; 116(8):630-8. doi: 10.1248/yakushi1947.116.8_630. [PMID: 8831264]
  • H S Yun-Choi, J H Kim, J R Lee. Potential inhibitors of platelet aggregation from plant sources, III. Journal of natural products. 1987 Nov; 50(6):1059-64. doi: 10.1021/np50054a008. [PMID: 3127544]