4-Methoxyresveratrol (BioDeep_00000267364)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


5-[2-(4-methoxyphenyl)vinyl]benzene-1,3-diol;(E)-5-(4-Methoxystyryl)benzene-1,3-diol

化学式: C15H14O3 (242.0942894)
中文名称: 白藜芦醇-4'-甲醚, 白藜芦醇-4’-甲醚, 白藜芦醇-4-甲醚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1c(ccc(c1)/C=C/c1cc(cc(c1)O)O)OC
InChI: InChI=1S/C15H14O3/c1-18-15-6-4-11(5-7-15)2-3-12-8-13(16)10-14(17)9-12/h2-10,16-17H,1H3/b3-2+

描述信息

5-[2-(4-methoxyphenyl)ethenyl]benzene-1,3-diol is a stilbenoid.
(E)-5-(4-Methoxystyryl)benzene-1,3-diol is a natural product found in Alpinia hainanensis, Rheum undulatum, and other organisms with data available.
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a polyphenol derived from Dipterocarpaceae, with antiandrogenic, antifungal and anti-inflammatory activities. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation[1].
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a polyphenol derived from Dipterocarpaceae, with antiandrogenic, antifungal and anti-inflammatory activities. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation[1].

同义名列表

37 个代谢物同义名

5-[2-(4-methoxyphenyl)vinyl]benzene-1,3-diol;(E)-5-(4-Methoxystyryl)benzene-1,3-diol; 1,3-BENZENEDIOL, 5-(2-(4-METHOXYPHENYL)ETHENYL)-, (E)-; 1,3-Benzenediol, 5-[(1E)-2-(4-methoxyphenyl)ethenyl]-; 1,3-Benzenediol, 5-[(E)-2-(4-methoxyphenyl)ethenyl]-; 5-[(E)-2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol; 5-((1E)-2-(4-METHOXYPHENYL)ETHENYL)-1,3-BENZENEDIOL; 5-[2-((E)-4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol; 5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene-1,3-diol; E 5-[2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol; 1,3-Benzenediol, 5-[2-(4-methoxyphenyl)ethenyl]-; 5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol; 5-[2-(4-Methoxy-phenyl)-vinyl]-benzene-1,3-diol; 5-[2-(4-Methoxyphenyl)ethenyl]-1,3-benzenediol; (E)-5-(4-Methoxystyryl)benzene-1,3-diol; 3,5-dihydroxy-4-methoxy-trans-stilbene; (E)-5-(4-Methoxystyryl)benzene-13-diol; trans-3,5-dihydroxy-4-methoxystilbene; (E)-3,5-DIHYDROXY-4-METHOXYSTILBENE; (E)-3,5-dihydroxy-4-methoxystilbene; 5-(4-methoxystyryl)benzene-1,3-diol; 13E-3,5-dihydroxy-4-methoxystilbene; 3,5-STILBENEDIOL, 4-METHOXY-, (E)-; 3,5-dihydroxy-4-methoxystilbene; IHVRWFJGOIWMGC-NSCUHMNNSA-N; RESVERATROL 4-METHYL ETHER; 4-O-Methylresveratrol; 4-Methoxyresveratrol; desoxyrhapontigenin; Desoxyrhaponigenin; deoxyrhapontigenin; Spectrum5_000570; UNII-RU7RRY3RUW; QTL1_000070; RU7RRY3RUW; DHMS cpd; 4'-O-Methylresveratrol; 4'-Methoxyresveratrol



数据库引用编号

13 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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58 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • SeonJu Park, Yun Na Kim, Hee Jae Kwak, Eun Ju Jeong, Seung Hyun Kim. Estrogenic activity of constituents from the rhizomes of Rheum undulatum Linné. Bioorganic & medicinal chemistry letters. 2018 02; 28(4):552-557. doi: 10.1016/j.bmcl.2018.01.063. [PMID: 29402747]
  • Syuhei Nakao, Miyuki Mabuchi, Shenglan Wang, Yoko Kogure, Tadashi Shimizu, Koichi Noguchi, Akito Tanaka, Yi Dai. Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor. Bioorganic & medicinal chemistry letters. 2017 07; 27(14):3167-3172. doi: 10.1016/j.bmcl.2017.05.025. [PMID: 28576617]
  • Sun-Young Kang, Jae Kyoung Lee, Oksik Choi, Cha Young Kim, Jae-Hyuk Jang, Bang Yeon Hwang, Young-Soo Hong. Biosynthesis of methylated resveratrol analogs through the construction of an artificial biosynthetic pathway in E. coli. BMC biotechnology. 2014 Jul; 14(?):67. doi: 10.1186/1472-6750-14-67. [PMID: 25033820]
  • Takakazu Mitani, Yuta Ito, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, Hitoshi Ashida, Ryoichi Yamaji. Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells. Journal of nutritional science and vitaminology. 2014; 60(2):122-8. doi: 10.3177/jnsv.60.122. [PMID: 24975222]
  • Ran Joo Choi, Mao-Sheng Cheng, Yeong Shik Kim. Desoxyrhapontigenin up-regulates Nrf2-mediated heme oxygenase-1 expression in macrophages and inflammatory lung injury. Redox biology. 2014; 2(?):504-12. doi: 10.1016/j.redox.2014.02.001. [PMID: 24624340]
  • Yuta Ito, Takakazu Mitani, Naoki Harada, Atsushi Isayama, Shinji Tanimori, Shigeo Takenaka, Yoshihisa Nakano, Hiroshi Inui, Ryoichi Yamaji. Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4'-amino-3,5-dihydroxy-trans-stilbene. Journal of nutritional science and vitaminology. 2013; 59(4):358-64. doi: 10.3177/jnsv.59.358. [PMID: 24064738]
  • Shiby Paul, Cassia S Mizuno, Hong Jin Lee, Xi Zheng, Sarah Chajkowisk, John M Rimoldi, Allan Conney, Nanjoo Suh, Agnes M Rimando. In vitro and in vivo studies on stilbene analogs as potential treatment agents for colon cancer. European journal of medicinal chemistry. 2010 Sep; 45(9):3702-8. doi: 10.1016/j.ejmech.2010.05.019. [PMID: 20627379]
  • K Suresh Babu, Ashok K Tiwari, Pullela V Srinivas, Amtul Z Ali, B China Raju, J Madhusudana Rao. Yeast and mammalian alpha-glucosidase inhibitory constituents from Himalayan rhubarb Rheum emodi Wall.ex Meisson. Bioorganic & medicinal chemistry letters. 2004 Jul; 14(14):3841-5. doi: 10.1016/j.bmcl.2004.04.062. [PMID: 15203173]
  • Zohar Kerem, Gilly Regev-Shoshani, Moshe A Flaishman, Lior Sivan. Resveratrol and two monomethylated stilbenes from Israeli Rumex bucephalophorus and their antioxidant potential. Journal of natural products. 2003 Sep; 66(9):1270-2. doi: 10.1021/np030087c. [PMID: 14510615]
  • L A Stivala, M Savio, F Carafoli, P Perucca, L Bianchi, G Maga, L Forti, U M Pagnoni, A Albini, E Prosperi, V Vannini. Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol. The Journal of biological chemistry. 2001 Jun; 276(25):22586-94. doi: 10.1074/jbc.m101846200. [PMID: 11316812]
  • H Matsuda, T Kageura, T Morikawa, I Toguchida, S Harima, M Yoshikawa. Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages. Bioorganic & medicinal chemistry letters. 2000 Feb; 10(4):323-7. doi: 10.1016/s0960-894x(99)00702-7. [PMID: 10714491]
  • D Min, L Xu, Z Zhang, H Wang, D Huang, D Guo, J Zheng. [Chemical constituents of Rheum wittrochii Lundstr(II)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1998 Aug; 23(8):486-8, 512. doi: ". [PMID: 11599372]
  • F Orsini, F Pelizzoni, L Verotta, T Aburjai, C B Rogers. Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds. Journal of natural products. 1997 Nov; 60(11):1082-7. doi: 10.1021/np970069t. [PMID: 9392877]
  • M Clements, G F Gray. Quadruple renal neoplasia: bilateral renal tumors of dissimilar histogenesis. The Journal of urology. 1979 Apr; 121(4):501-2. doi: 10.1016/s0022-5347(17)56843-3. [PMID: 439230]