Rhamnazin (BioDeep_00000022147)

human metabolite PANOMIX_OTCML-2023

代谢物信息卡片

Rhamnazin

化学式: C17H14O7 (330.0739494)
中文名称: 3,7-二甲氧基-3,4,5-三羟基黄酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=C2C(=C1)OC(=C(C2=O)O)C3=CC(=C(C=C3)O)OC)O
InChI: InChI=1S/C17H14O7/c1-22-9-6-11(19)14-13(7-9)24-17(16(21)15(14)20)8-3-4-10(18)12(5-8)23-2/h3-7,18-19,21H,1-2H3

描述信息

同义名列表

1 个代谢物同义名

Rhamnazin

数据库引用编号

7 个数据库交叉引用编号

ChEBI: CHEBI:133721
PubChem: 5320945
HMDB: HMDB0133830
ChEMBL: CHEMBL457148
MetaCyc: CPD-14947
CAS: 552-54-5
PMhub: MS000078896

分类词条

代谢反应

12 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(11)

polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + quercetin ⟶ H⁺ + SAH + isorhamnetin
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH
polymethylated quercetin biosynthesis: SAM + rhamnetin ⟶ 7,3'-dimethylquercetin + H⁺ + SAH

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

54 个相关的物种来源信息

746491 - Achyrocline alata: 10.1016/0305-1978(93)90051-R
1548826 - Achyrocline tomentosa: 10.1016/0305-1978(88)90032-4
35945 - Aeonium arboreum: 10.1016/0031-9422(93)00074-P
111149 - Aeonium decorum: 10.1016/0031-9422(93)00074-P
109063 - Alnus japonica: 10.1016/0031-9422(74)85049-1
4214 - Ambrosia trifida:
1053409 - Ammi visnaga: 10.1055/S-2006-960912
414592 - Argyrochosma nivea: 10.1016/0031-9422(93)85457-3
72337 - Artemisia campestris: 10.1016/S0305-1978(02)00178-3
72339 - Artemisia chamaemelifolia: 10.1515/ZNC-1995-5-604
401898 - Artemisia gmelinii: 10.1515/ZNC-1995-5-604
72348 - Artemisia monosperma: 10.1016/0031-9422(90)85231-4
205376 - Artemisia santolinifolia: 10.1515/ZNC-1995-5-604
313920 - Blumea balsamifera: 10.1016/J.FITOTE.2004.10.015
1603704 - Callicarpa kwangtungensis: 10.1371/JOURNAL.PONE.0093000
2321258 - Capparicordis tweediana: 10.1016/S0305-1978(97)00122-1
335163 - Cistus albidus: 10.1515/ZNC-1984-3-418
335179 - Cistus laurifolius:
335184 - Cistus monspeliensis: 10.1515/ZNC-1984-3-418
34317 - Eucalyptus globulus: 10.1007/BF02975503
1619452 - Eucryphia jinksii: 10.1016/S0305-1978(99)00045-9
231905 - Garcinia dulcis: 10.1016/J.PHYTOCHEM.2005.10.016
239185 - Halocnemum strobilaceum: 10.1007/BF02238224
71055 - Hazardia squarrosa: 10.1016/S0031-9422(00)83207-0
9606 - Homo sapiens: -
2021211 - Indocypraea montana: 10.1016/0031-9422(93)85152-H
467321 - Koenigia polystachya: 10.1039/CT8956701084
441197 - Laggera alata: 10.1021/NP0205856
108398 - Larrea cuneifolia: 10.1016/S0031-9422(00)86519-X
4255 - Madia elegans: 10.1515/ZNC-2003-3-401
235752 - Miliusa horsfieldii: 10.1055/S-2002-33804
1424733 - Mirabilis viscosa: 10.1016/S0305-1978(96)00081-6
909280 - Mutisia orbignyana: 10.1016/0031-9422(88)84114-1
65948 - Nasturtium officinale: 10.1248/BPB.22.1319
1168071 - Nervilia fordii: 10.1021/NP800760P
500429 - Notholaena neglecta: 10.1021/NP50020A019
86853 - Nymphoides geminata: 10.1002/J.1537-2197.1986.TB08521.X
105901 - Nymphoides indica: 10.1002/J.1537-2197.1986.TB08521.X
904380 - Oxytropis oxyphylla: 10.1007/BF00598374
2005178 - Oxytropis sylvatica: 10.1007/BF00598374
73621 - Palhinhaea cernua:
340645 - Passiflora palmeri: 10.1021/NP50032A028
176559 - Pericome caudata: 10.1016/S0031-9422(00)82480-2
46901 - Persicaria hydropiper: 10.1007/BF00580088
137688 - Persicaria punctata: 10.1039/CT8956701084
2650213 - Polanisia trachysperma: 10.1016/0031-9422(89)85071-X
49838 - Retama sphaerocarpa:
3610 - Rhamnus cathartica: 10.1016/S0031-9422(99)00262-9
1813078 - Rhamnus disperma: 10.1016/S0031-9422(99)00262-9
72169 - Rhamnus lycioides: 10.1515/ZNC-1986-11-1204
280022 - Rhamnus prinoides:
33121 - Salpiglossis sinuata: 10.1016/0305-1978(95)00017-O
174478 - Traversia baccharoides: 10.1139/V86-081
101473 - Wollastonia biflora: 10.1016/0031-9422(93)85152-H

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Fei Mei, Yuan Liu, Shuang Zheng. Rhamnazin Inhibits Hepatocellular Carcinoma Cell Aggressiveness in Vitro via Glutathione Peroxidase 4-Dependent Ferroptosis. The Tohoku journal of experimental medicine. 2022 Sep; 258(2):111-120. doi: 10.1620/tjem.2022.j061. [PMID: 35896364]
Xue-Yi Wu, Tian Wang, Hui-Xin Hu, Kan Zhang, Yu Zhao, Bao-Bing Zhao, Hong-Xiang Lou, Xiao-Ning Wang, Tao Shen. The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders. Phytotherapy research : PTR. 2022 Apr; 36(4):1692-1707. doi: 10.1002/ptr.7403. [PMID: 35129872]
Wenjuan Wang, Yuanyuan Liu, Fenfang Che, Hao Li, Jiangang Liu, Nan Wu, Yanxiang Gu, Yun Wei. Isolation and purification of flavonoids from Euonymus alatus by high-speed countercurrent chromatography and neuroprotective effect of rhamnazin-3-O-rutinoside in vitro. Journal of separation science. 2021 Dec; 44(24):4422-4430. doi: 10.1002/jssc.202100607. [PMID: 34670011]
Tran Manh Hung, Joo Sang Lee, Nguyen Ngoc Chuong, Jeong Ah Kim, Sang Ho Oh, Mi Hee Woo, Jae Sue Choi, Byung Sun Min. Kinetics and molecular docking studies of cholinesterase inhibitors derived from water layer of Lycopodiella cernua (L.) Pic. Serm. (II). Chemico-biological interactions. 2015 Oct; 240(?):74-82. doi: 10.1016/j.cbi.2015.07.008. [PMID: 26297990]
Li Zhang, Chen-chen Zhu, Zhong-xiang Zhao, Chao-zhan Lin. [Simultaneous determination of seven flavonoids in Nervilia fordii with HPLC]. Yao xue xue bao = Acta pharmaceutica Sinica. 2011 Oct; 46(10):1237-40. doi: . [PMID: 22242457]
Jie Zhang, Baoquan Li, Feng Feng, Yuping Tang, Wenyuan Liu. [Chemical constituents from Callicarpa nudiflora and their hemostatic activity]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Dec; 35(24):3297-301. doi: . [PMID: 21438394]
Li-Wen Tian, Ying Pei, Ying-Jun Zhang, Yi-Fei Wang, Chong-Ren Yang. 7-O-methylkaempferol and -quercetin glycosides from the whole plant of Nervilia fordii. Journal of natural products. 2009 Jun; 72(6):1057-60. doi: 10.1021/np800760p. [PMID: 19422205]
Guang-Xiong Zhou, Chuan-Li Lu, Heng-Shan Wang, Xin-Sheng Yao. An acetyl flavonol from Nervilia fordii (Hance) Schltr. Journal of Asian natural products research. 2009 Jun; 11(6):498-502. doi: 10.1080/10286020902893074. [PMID: 20183281]
Chuan-Li Lu, Guang-Xiong Zhou, Heng-Shan Wang, Yao-Lan Li, Xin-Sheng Yao. [Studies on the chemical constituents of Nerviliae fordii]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2009 Mar; 32(3):373-5. doi: . [PMID: 19565714]
Han-shen Zhen, Yan-yuan Zhou, Ye-fei Yuan, Huan-heng Mo, Zhen-guo Zhong, Chen-yan Liang. [Studies on the chemical constituents of the ethyl acetate portion of Nervilia fordii]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2007 Aug; 30(8):942-5. doi: . [PMID: 18074840]
N D Martini, D R P Katerere, J N Eloff. Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae). Journal of ethnopharmacology. 2004 Aug; 93(2-3):207-12. doi: 10.1016/j.jep.2004.02.030. [PMID: 15234754]
M López-Lázaro, C Martín-Cordero, F Cortés, J Piñero, M J Ayuso. Cytotoxic activity of flavonoids and extracts from Retama sphaerocarpa Boissier. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2000 Jan; 55(1-2):40-3. doi: 10.1515/znc-2000-1-209. [PMID: 10739098]
H Haraguchi, I Ohmi, S Sakai, A Fukuda, Y Toihara, T Fujimoto, N Okamura, A Yagi. Effect of Polygonum hydropiper sulfated flavonoids on lens aldose reductase and related enzymes. Journal of natural products. 1996 Apr; 59(4):443-5. doi: 10.1021/np9601622. [PMID: 8699190]
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