3-Chloro-D-alanine (BioDeep_00001869839)

Main id: BioDeep_00000004957

 

natural product


代谢物信息卡片


3-Chloro-D-alanine

化学式: C3H6ClNO2 (123.0087)
中文名称: (S)-2-氨基-3-氯丙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(=O)O)N)Cl
InChI: InChI=1S/C3H6ClNO2/c4-1-2(5)3(6)7/h2H,1,5H2,(H,6,7)/t2-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

3-Chloro-D-alanine



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jorge Cerbon, Teresa Olguin, Pindaro R Alvarez-Grave, Rosa C López-Sánchez. Entamoeba invadens: sphingolipids metabolic regulation is the main component of a PKC signaling pathway in controlling cell growth and proliferation. Experimental parasitology. 2009 Jun; 122(2):106-11. doi: 10.1016/j.exppara.2009.02.011. [PMID: 19249300]
  • Jorge Cerbón, Alejandro Falcon, Carlos Hernández-Luna, David Segura-Cobos. Inositol phosphoceramide synthase is a regulator of intracellular levels of diacylglycerol and ceramide during the G1 to S transition in Saccharomyces cerevisiae. The Biochemical journal. 2005 May; 388(Pt 1):169-76. doi: 10.1042/bj20040475. [PMID: 15560753]
  • Kumar Babita, Ashok Kumar Tiwary. Skin lipid synthesis inhibition: a possible means for enhancing percutaneous delivery of levodopa. Current drug delivery. 2004 Oct; 1(4):397-403. doi: 10.2174/1567201043334579. [PMID: 16305401]
  • M Gupta, A Mahajan, Babita, S Gupta, A K Tiwary. Inhibition of skin sphingosine synthesis: enhanced percutaneous permeation of 5-fluorouracil. Die Pharmazie. 2004 Mar; 59(3):212-6. doi: . [PMID: 15074596]
  • Arthur J L Cooper, Boris F Krasnikov, Etsuo Okuno, Thomas M Jeitner. L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?. The Biochemical journal. 2003 Nov; 376(Pt 1):169-78. doi: 10.1042/bj20030988. [PMID: 12859250]
  • Brooke S Wright, Jonathan W Snow, Theresa C O'Brien, Daniel V Lynch. Synthesis of 4-hydroxysphinganine and characterization of sphinganine hydroxylase activity in corn. Archives of biochemistry and biophysics. 2003 Jul; 415(2):184-92. doi: 10.1016/s0003-9861(03)00261-3. [PMID: 12831841]
  • Arthur J L Cooper, Sam A Bruschi, Ana Iriarte, Marino Martinez-Carrion. Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions. The Biochemical journal. 2002 Nov; 368(Pt 1):253-61. doi: 10.1042/bj20020531. [PMID: 12137566]
  • Babita S Gupta, A K Tiwary. Role of sphingosine synthesis inhibition in transcutaneous delivery of levodopa. International journal of pharmaceutics. 2002 May; 238(1-2):43-50. doi: 10.1016/s0378-5173(02)00063-7. [PMID: 11996809]
  • Yuki Ogasawara, Kazuyuki Ishii, Shinzo Tanabe. Enzymatic assay of gamma-cystathionase activity using pyruvate oxidase-peroxidase sequential reaction. Journal of biochemical and biophysical methods. 2002 Apr; 51(2):139-50. doi: 10.1016/s0165-022x(02)00010-6. [PMID: 12062113]
  • P Kovács. The effect of beta-chloro D-alanine and L-cycloserine on the serine, phosphorus and palmitic acid uptake and metabolism of Tetrahymena lipids. Acta biologica Hungarica. 1999; 50(4):363-73. doi: . [PMID: 10735173]
  • H S Yoo, W P Norred, J Showker, R T Riley. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. Toxicology and applied pharmacology. 1996 Jun; 138(2):211-8. doi: 10.1006/taap.1996.0119. [PMID: 8658522]
  • M H Medeiros, P Di Mascio, S Gründel, S Soboll, H Sies, E J Bechara. Catabolism of 5-aminolevulinic acid to CO2 by rat liver mitochondria. Archives of biochemistry and biophysics. 1994 Apr; 310(1):205-9. doi: 10.1006/abbi.1994.1158. [PMID: 8161206]
  • M Mao-Qiang, K R Feingold, P M Elias. Inhibition of cholesterol and sphingolipid synthesis causes paradoxical effects on permeability barrier homeostasis. The Journal of investigative dermatology. 1993 Aug; 101(2):185-90. doi: 10.1111/1523-1747.ep12363729. [PMID: 8345219]
  • S A Ahmed, E W Miles. Evidence for two conformers of the beta subunit of tryptophan synthase in solution. The Journal of biological chemistry. 1992 Nov; 267(32):23309-17. doi: 10.1016/s0021-9258(18)50092-2. [PMID: 1429678]
  • S A Ahmed, S B Ruvinov, A M Kayastha, E W Miles. Mechanism of mutual activation of the tryptophan synthase alpha and beta subunits. Analysis of the reaction specificity and substrate-induced inactivation of active site and tunnel mutants of the beta subunit. The Journal of biological chemistry. 1991 Nov; 266(32):21548-57. doi: NULL. [PMID: 1939184]
  • W M Holleran, M Q Man, W N Gao, G K Menon, P M Elias, K R Feingold. Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation. The Journal of clinical investigation. 1991 Oct; 88(4):1338-45. doi: 10.1172/jci115439. [PMID: 1918384]
  • K A Medlock, A H Merrill. Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by beta-chloroalanine. Biochemistry. 1988 Sep; 27(18):7079-84. doi: 10.1021/bi00418a061. [PMID: 3143407]
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