Reaction Process: Reactome:R-CEL-2408508

Metabolism of ingested SeMet, Sec, MeSec into H2Se related metabolites

find 3 related metabolites which is associated with chemical reaction(pathway) Metabolism of ingested SeMet, Sec, MeSec into H2Se

Sec ⟶ H2Se + L-Ala

Hydrogen selenide

Hydrogen selenide, 75Se-labeled

H2Se (81.9322)


Hydrogen selenide is a metabolite of selenium which could have potential antiangiogenic effect in the chemoprevention of cancer. The hydrogen selenide is a key intermediate in the selenium methylation metabolism of inorganic and organic selenium compounds. Accumulation of the hydrogen selenide resulting from inhibition of the selenium methylation metabolism, detoxification metabolic pathway of selenium, is found in animals following repeated administration of a toxic dose of selenocystine. The excess of the hydrogen selenide produced by inhibition of the selenium methylation metabolism contributes to the hepatotoxicity caused by selenocystine. (PMID: 9414580, 11799926) [HMDB] Hydrogen selenide is a metabolite of selenium which could have potential antiangiogenic effect in the chemoprevention of cancer. The hydrogen selenide is a key intermediate in the selenium methylation metabolism of inorganic and organic selenium compounds. Accumulation of the hydrogen selenide resulting from inhibition of the selenium methylation metabolism, detoxification metabolic pathway of selenium, is found in animals following repeated administration of a toxic dose of selenocystine. The excess of the hydrogen selenide produced by inhibition of the selenium methylation metabolism contributes to the hepatotoxicity caused by selenocystine. (PMID: 9414580, 11799926).

   

selenocysteine

3-Selenoalanine

C3H6NO2Se (167.9564)


   

(2S)-2-azaniumylpropanoate

(2S)-2-azaniumylpropanoate

C3H7NO2 (89.0477)