NCBI Taxonomy: 85258
Rinorea (ncbi_taxid: 85258)
found 8 associated metabolites at genus taxonomy rank level.
Ancestor: Violaceae
Child Taxonomies: Rinorea riana, Rinorea ovata, Rinorea mutica, Rinorea obtusa, Rinorea sinuata, Rinorea arborea, Rinorea batesii, Rinorea crenata, Rinorea bullata, Rinorea cinerea, Rinorea horneri, Rinorea dentata, Rinorea prasina, Rinorea spinosa, Rinorea urschii, Rinorea virgata, Rinorea caudata, Rinorea mezilii, Rinorea dewitii, Rinorea hummelii, Rinorea squamata, Rinorea liberica, Rinorea microdon, Rinorea thomasii, Rinorea preussii, Rinorea calycina, Rinorea greveana, Rinorea longipes, Rinorea neglecta, Rinorea racemosa, Rinorea squamosa, Rinorea talbotii, Rinorea zenkerii, Rinorea simoneae, Rinorea anguifera, Rinorea sylvatica, Rinorea kemoensis, Rinorea umbricola, Rinorea amapensis, Rinorea bahiensis, Rinorea beniensis, Rinorea domatiosa, Rinorea elliptica, Rinorea laurentii, Rinorea apiculata, Rinorea monticola, Rinorea ramiziana, Rinorea pubiflora, Rinorea letouzeyi, Rinorea verrucosa, Rinorea ilicifolia, Rinorea yaundensis, Rinorea auriculata, Rinorea chevalieri, Rinorea flavescens, Rinorea guianensis, Rinorea iliaspaiei, Rinorea kibbiensis, Rinorea macrocarpa, Rinorea pauciflora, Rinorea zygomorpha, Rinorea campoensis, Rinorea lanceolata, Rinorea leiophylla, Rinorea gabunensis, Rinorea bengalensis, Rinorea claessensii, Rinorea rubrotincta, Rinorea crassifolia, Rinorea mildbraedii, Rinorea pugionifera, Rinorea welwitschii, Rinorea albidiflora, Rinorea ledermannii, Rinorea longicuspis, Rinorea longisepala, Rinorea deflexiflora, Rinorea brachypetala, Rinorea diversifolia, Rinorea lepidobotrys, unclassified Rinorea, Rinorea angustifolia, Rinorea kamerunensis, Rinorea oblongifolia, Rinorea woermanniana, Rinorea subauriculata, Rinorea breviracemosa, Rinorea exappendiculata, Rinorea convallarioides, Rinorea pectinosquamata, Rinorea subintegrifolia, Rinorea cf. keayi Luke 10365, Rinorea cf. arborea GAW-2012, Rinorea cf. sclerocarpa KR0927, Rinorea cf. sclerocarpa KR0655, Rinorea cf. sclerocarpa KR0654, Rinorea cf. kemoensis Sonke 2664, Rinorea cf. ilicifolia Achoundong 2337, Rinorea cf. ebolowensis van Andel 3620, Rinorea cf. exappendiculata Wieringa 4382, Rinorea cf. angustifolia Luke & Luke 13003
Camptothecin
Camptothecin is a pyranoindolizinoquinoline that is pyrano[3,4:6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an antineoplastic agent, a genotoxin and a plant metabolite. It is a pyranoindolizinoquinoline, a tertiary alcohol, a delta-lactone and a quinoline alkaloid. Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. Camptothecin is a natural product found in Archidendron lucidum, Merrilliodendron megacarpum, and other organisms with data available. Camptothecin is an alkaloid isolated from the Chinese tree Camptotheca acuminata, with antineoplastic activity. During the S phase of the cell cycle, camptothecin selectively stabilizes topoisomerase I-DNA covalent complexes, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery. (NCI) An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity. A pyranoindolizinoquinoline that is pyrano[3,4:6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3]. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].
(+)-Syringaresinol
(+)-syringaresinol is a member of the class of compounds known as furanoid lignans. Furanoid lignans are lignans with a structure that contains either a tetrahydrofuran ring, a furan ring, or a furofuan ring system, that arises from the joining of the two phenylpropanoid units (+)-syringaresinol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (+)-syringaresinol can be found in a number of food items such as radish (variety), grape wine, oat, and ginkgo nuts, which makes (+)-syringaresinol a potential biomarker for the consumption of these food products.
Mauritianin
Syringaresinol
(+)-syringaresinol is the (7alpha,7alpha,8alpha,8alpha)-stereoisomer of syringaresinol. It has a role as an antineoplastic agent. It is an enantiomer of a (-)-syringaresinol. (+)-Syringaresinol is a natural product found in Dracaena draco, Diospyros eriantha, and other organisms with data available. See also: Acai fruit pulp (part of). The (7alpha,7alpha,8alpha,8alpha)-stereoisomer of syringaresinol.
