NCBI Taxonomy: 768507
Cytophagales (ncbi_taxid: 768507)
found 123 associated metabolites at order taxonomy rank level.
Ancestor: Cytophagia
Child Taxonomies: Raineyaceae, Mooreiaceae, Shiellaceae, Cytophagaceae, Marivirgaceae, Fulvivirgaceae, Roseivirgaceae, Microscillaceae, Bernardetiaceae, Amoebophilaceae, Spirosomataceae, Flexibacteraceae, Thermonemataceae, Catalimonadaceae, Flammeovirgaceae, Cesiribacteraceae, Hymenobacteraceae, Cyclobacteriaceae, Mangrovivirgaceae, Rhodocytophagaceae, Persicobacteraceae, Reichenbachiellaceae, Thermoflexibacteraceae, unclassified Cytophagales, Cytophagales incertae sedis
Zeaxanthin
Zeaxanthin is a carotenoid xanthophyll and is one of the most common carotenoid found in nature. It is the pigment that gives corn, saffron, and many other plants their characteristic color. Zeaxanthin breaks down to form picrocrocin and safranal, which are responsible for the taste and aroma of saffron Carotenoids are among the most common pigments in nature and are natural lipid soluble antioxidants. Zeaxanthin is one of the two carotenoids (the other is lutein) that accumulate in the eye lens and macular region of the retina with concentrations in the macula greater than those found in plasma and other tissues. Lutein and zeaxanthin have identical chemical formulas and are isomers, but they are not stereoisomers. The main difference between them is in the location of a double bond in one of the end rings. This difference gives lutein three chiral centers whereas zeaxanthin has two. A relationship between macular pigment optical density, a marker of lutein and zeaxanthin concentration in the macula, and lens optical density, an antecedent of cataractous changes, has been suggested. The xanthophylls may act to protect the eye from ultraviolet phototoxicity via quenching reactive oxygen species and/or other mechanisms. Some observational studies have shown that generous intakes of lutein and zeaxanthin, particularly from certain xanthophyll-rich foods like spinach, broccoli and eggs, are associated with a significant reduction in the risk for cataract (up to 20\\%) and for age-related macular degeneration (up to 40\\%). While the pathophysiology of cataract and age-related macular degeneration is complex and contains both environmental and genetic components, research studies suggest dietary factors including antioxidant vitamins and xanthophylls may contribute to a reduction in the risk of these degenerative eye diseases. Further research is necessary to confirm these observations. (PMID: 11023002). Zeaxanthin has been found to be a microbial metabolite, it can be produced by Algibacter, Aquibacter, Escherichia, Flavobacterium, Formosa, Gramella, Hyunsoonleella, Kordia, Mesoflavibacter, Muricauda, Nubsella, Paracoccus, Siansivirga, Sphingomonas, Zeaxanthinibacter and yeast (https://reader.elsevier.com/reader/sd/pii/S0924224417302571?token=DE6BC6CC7DCDEA6150497AA3E375097A00F8E0C12AE03A8E420D85D1AC8855E62103143B5AE0B57E9C5828671F226801). It is a marker for the activity of Bacillus subtilis and/or Pseudomonas aeruginosa in the intestine. Higher levels are associated with higher levels of Bacillus or Pseudomonas. (PMID: 17555270; PMID: 12147474) Zeaxanthin is a carotenol. It has a role as a bacterial metabolite, a cofactor and an antioxidant. It derives from a hydride of a beta-carotene. Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some micro-organisms. It gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries. Zeaxanthin is one of the two primary xanthophyll carotenoids contained within the retina of the eye and plays a predominant component in the central macula. It is available as a dietary supplement for eye health benefits and potential prevention of age-related macular degeneration. Zeaxanthin is also added as a food dye. Zeaxanthin is a natural product found in Bangia fuscopurpurea, Erythrobacter longus, and other organisms with data available. Carotenoids found in fruits and vegetables. Zeaxanthin accumulates in the MACULA LUTEA. See also: Saffron (part of); Corn (part of); Lycium barbarum fruit (part of). D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
Zeaxanthin
Meso-zeaxanthin (3R,3´S-zeaxanthin) is a xanthophyll carotenoid, as it contains oxygen and hydrocarbons, and is one of the three stereoisomers of zeaxanthin. Of the three stereoisomers, meso-zeaxanthin is the second most abundant in nature after 3R,3´R-zeaxanthin, which is produced by plants and algae. To date, meso-zeaxanthin has been identified in specific tissues of marine organisms and in the macula lutea, also known as the "yellow spot", of the human retina . Meso-zeaxanthin is a member of the class of compounds known as xanthophylls. Xanthophylls are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone. Meso-zeaxanthin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Meso-zeaxanthin can be found in channel catfish, crustaceans, and fishes, which makes meso-zeaxanthin a potential biomarker for the consumption of these food products. D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids Window width for selecting the precursor ion was 3 Da.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
Marinoquinoline A
A pyrroloquinoline that is 3H-pyrrolo[2,3-c]quinoline substituted by a methyl group at position 4. It is a natural product found in Ohtaekwangia kribbensis and Rapidithrix thailandica.
Flexirubin
The parent member of the class of flexirubins obtained by formal condensation of the carboxy group of 17-(4-hydroxy-3-methylphenyl)heptadeca-2,4,6,8,10,12,14,16-octaenoic acid with one of the phenolic hydroxy groups of 2-dodecyl-5-methyl resorcinol.
Marinoquinoline B
A pyrroloquinoline that is 3H-pyrrolo[2,3-c]quinoline substituted by an isobutyl group at position 4. It is a natural product found in Ohtaekwangia kribbensis.
(2s)-2-{[(2r)-2-amino-1-hydroxy-4-methylpentylidene]amino}-n-[(3s,6s,12s,15s,18r,21s,24s,27s,28r)-18-(3-carbamimidamidopropyl)-5,8,11,14,17,20,23,26-octahydroxy-6-[(s)-hydroxy(c-hydroxycarbonimidoyl)methyl]-24-[(1r)-1-hydroxy-2-methylpropyl]-12-[(1s)-1-hydroxyethyl]-3-(hydroxymethyl)-15-isopropyl-21-(2-methylbutyl)-2-oxo-28-phenyl-1-oxa-4,7,10,13,16,19,22,25-octaazacyclooctacosa-4,7,10,13,16,19,22,25-octaen-27-yl]-4-methylpentanimidic acid
3-benzyl-5-methyl-6-(6-methylheptyl)-1h-pyrazin-2-one
6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-23-hydroxy-3,7,12,16,20,24-hexamethyl-24-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}pentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
(2s,3r)-3-hydroxy-2-{[(2s)-1-hydroxy-2-[(1-hydroxy-2-phenylethylidene)amino]-3-phenylpropylidene]amino}-n-[(3r,6s,9s,14s,17s,18r)-5,8,11,16-tetrahydroxy-6-(c-hydroxycarbonimidoylmethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,12,13-trioxo-1-oxa-4,7,10,15-tetraazacyclooctadeca-4,7,10,15-tetraen-17-yl]butanimidic acid
3-[(4-hydroxyphenyl)methyl]-5-methyl-6-(8-methylnonyl)-1h-pyrazin-2-one
C22H32N2O2 (356.24636519999996)
3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-24-hydroxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
4-[(2r)-1,3,3-trimethylaziridin-2-yl]quinolin-2-ol
C14H16N2O (228.12625659999998)
(6s)-6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e,23s)-24-hydroxy-23-methoxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
(2s)-2-{[(2r)-2-amino-1-hydroxy-4-methylpentylidene]amino}-n-[(3s,6s,12s,15s,18r,21s,24s,27s,28r)-18-(3-carbamimidamidopropyl)-5,8,11,14,17,20,23,26-octahydroxy-6-[(s)-hydroxy(c-hydroxycarbonimidoyl)methyl]-24-[(1r)-1-hydroxy-2-methylpropyl]-12-[(1s)-1-hydroxyethyl]-3-(hydroxymethyl)-15-isopropyl-21-(2-methylpropyl)-2-oxo-28-phenyl-1-oxa-4,7,10,13,16,19,22,25-octaazacyclooctacosa-4,7,10,13,16,19,22,25-octaen-27-yl]-4-methylpentanimidic acid
(2s,3s,4s,5r,6s)-6-{4-[(r)-[(3s)-3-[(2-{4-[(3r)-3-amino-3-carboxypropoxy]phenyl}-1,2-dihydroxyethylidene)amino]-3-[(hydroxymethylidene)amino]-2-oxoazetidin-1-yl](carboxy)methyl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
(2s,3r)-3-hydroxy-2-{[(2s)-1-hydroxy-2-[(1-hydroxy-3-methylbutylidene)amino]-3-phenylpropylidene]amino}-n-[(3r,6s,9s,14s,17s,18r)-5,8,11,16-tetrahydroxy-6-(c-hydroxycarbonimidoylmethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,12,13-trioxo-1-oxa-4,7,10,15-tetraazacyclooctadeca-4,7,10,15-tetraen-17-yl]butanimidic acid
(6s)-6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-24-hydroxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
4-(2-methylpropyl)pyrrolo[2,3-c]quinolin-3-ol
C15H16N2O (240.12625659999998)
3-(24-hydroxy-23-methoxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl)-2,4,4-trimethylcyclohex-2-en-1-one
6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21z)-24-hydroxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
(2s)-2-{[(2r)-2-amino-1-hydroxy-4-methylpentylidene]amino}-n-[(3s,6s,12r,15s,18r,21s,24s,27s,28s)-15-[(2r)-butan-2-yl]-18-(3-carbamimidamidopropyl)-5,8,11,14,17,20,23,26-octahydroxy-6-[(s)-hydroxy(c-hydroxycarbonimidoyl)methyl]-24-[(1s)-1-hydroxy-2-methylpropyl]-12-[(1r)-1-hydroxyethyl]-3-(hydroxymethyl)-21-(2-methylpropyl)-2-oxo-28-phenyl-1-oxa-4,7,10,13,16,19,22,25-octaazacyclooctacosa-4,7,10,13,16,19,22,25-octaen-27-yl]-4-methylpentanimidic acid
6-(4-{[3-({2-[4-(3-amino-3-carboxypropoxy)phenyl]-1,2-dihydroxyethylidene}amino)-3-[(hydroxymethylidene)amino]-2-oxoazetidin-1-yl](carboxy)methyl}phenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
(3s)-3-amino-6-carbamimidamido-n-[(5r)-4-hydroxy-2-(c-hydroxycarbonimidoylamino)-5,6-dihydropyrimidin-5-yl]-n-methylhexanamide
3,8,15,20-tetraoxatricyclo[20.2.2.2¹⁰,¹³]octacosa-1(24),10,12,22,25,27-hexaene-2,9,14,21-tetrone
2-amino-n-(1-{[18-(3-carbamimidamidopropyl)-5,8,11,14,17,20,23,26-octahydroxy-6-[hydroxy(c-hydroxycarbonimidoyl)methyl]-24-(1-hydroxy-2-methylpropyl)-12-(1-hydroxyethyl)-3-(hydroxymethyl)-21-(2-methylpropyl)-2-oxo-28-phenyl-15-(sec-butyl)-1-oxa-4,7,10,13,16,19,22,25-octaazacyclooctacosa-4,7,10,13,16,19,22,25-octaen-27-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl)-4-methylpentanimidic acid
6-hydroxy-3-{23-hydroxy-3,7,12,16,20,24-hexamethyl-24-[(3,4,5-trihydroxyoxan-2-yl)oxy]pentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl}-2,4,4-trimethylcyclohex-2-en-1-one
3-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-3-methylbutylidene)amino]-3-phenylpropylidene}amino)-n-[5,8,11,16-tetrahydroxy-6-(c-hydroxycarbonimidoylmethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,12,13-trioxo-1-oxa-4,7,10,15-tetraazacyclooctadeca-4,7,10,15-tetraen-17-yl]butanimidic acid
({1-hydroxy-15-methyl-3-[(13-methyltetradec-4-enoyl)oxy]hexadecylidene}amino)acetic acid
[(1-hydroxy-15-methyl-3-{[(4z)-13-methyltetradec-4-enoyl]oxy}hexadecylidene)amino]acetic acid
6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-24-hydroxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
(2s)-3-hydroxy-2-{[(2s)-1-hydroxy-2-[(1-hydroxy-2-phenylethylidene)amino]-3-phenylpropylidene]amino}-n-[(3r,6s,9s,17s)-5,8,11,16-tetrahydroxy-6-(c-hydroxycarbonimidoylmethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,12,13-trioxo-1-oxa-4,7,10,15-tetraazacyclooctadeca-4,7,10,15-tetraen-17-yl]butanimidic acid
n-[2-(1h-indol-3-yl)ethyl]-3-methylbutanimidic acid
({1-hydroxy-14-methyl-3-[(13-methyltetradec-4-enoyl)oxy]pentadecylidene}amino)acetic acid
3-{[5-(1h-indol-3-ylmethyl)pyrazin-2-yl]methyl}-1h-indole
{[(3r)-1-hydroxy-3-[(13-methyltetradecanoyl)oxy]hexadecylidene]amino}acetic acid
{[(3r)-1-hydroxy-15-methyl-3-[(13-methyltetradecanoyl)oxy]hexadecylidene]amino}acetic acid
24-[(2-amino-1,3-dihydroxybutylidene)amino]-15-benzyl-8,17,20,23,30,33,35,39,46-nonahydroxy-32-(1h-indol-3-ylmethyl)-25-methyl-21-(2-methylpropyl)-3,14,27-trioxo-4,26-dioxa-7,13,16,19,22,31,34,36,40,45-decaazatetracyclo[16.16.10.2⁶,²⁹.0⁹,¹³]hexatetraconta-7,16,19,22,30,33,35,39,45-nonaene-37-carboxylic acid
C60H79N13O18 (1269.5665754000001)
3-hydroxy-2-({1-hydroxy-2-[(1-hydroxy-2-phenylethylidene)amino]-3-phenylpropylidene}amino)-n-[5,8,11,16-tetrahydroxy-6-(c-hydroxycarbonimidoylmethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,12,13-trioxo-1-oxa-4,7,10,15-tetraazacyclooctadeca-4,7,10,15-tetraen-17-yl]butanimidic acid
3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-24-hydroxy-23-methoxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
6-hydroxy-3-[(1e,3e,5e,7e,9e,11e,13e,15e,17e,19e,21e)-24-hydroxy-23-methoxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one
{[(3s)-1-hydroxy-14-methyl-3-{[(4z)-13-methyltetradec-4-enoyl]oxy}pentadecylidene]amino}acetic acid
(2s)-3-hydroxy-2-[(1-hydroxy-2-{[(3r)-1-hydroxy-3-[(13-methyltetradecanoyl)oxy]hexadecylidene]amino}ethylidene)amino]propanoic acid
(7e,15e,19e)-4,6,12,18-tetrahydroxy-21-methyl-10-methylidene-22-[(1e,3z,5z)-3-methylnona-1,3,5,8-tetraen-1-yl]-1-oxacyclodocosa-7,15,19-trien-2-one
6-(aminomethyl)-2-{[(4e)-2-[(1,2-dihydroxy-12-methyltridecylidene)amino]-3-hydroxy-18-methylnonadec-4-en-1-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
2-amino-n-(1-{[18-(3-carbamimidamidopropyl)-5,8,11,14,17,20,23,26-octahydroxy-6-[hydroxy(c-hydroxycarbonimidoyl)methyl]-24-(1-hydroxy-2-methylpropyl)-12-(1-hydroxyethyl)-3-(hydroxymethyl)-15-isopropyl-21-(2-methylpropyl)-2-oxo-28-phenyl-1-oxa-4,7,10,13,16,19,22,25-octaazacyclooctacosa-4,7,10,13,16,19,22,25-octaen-27-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl)-4-methylpentanimidic acid
(7e,15e,19e)-4,6,12,18-tetrahydroxy-21-methyl-10-methylidene-22-[(2z,4z,6e)-3-methylnona-2,4,6,8-tetraen-1-yl]-1-oxacyclodocosa-7,15,19-trien-2-one
6-hydroxy-3-(24-hydroxy-23-methoxy-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,21-undecaen-1-yl)-2,4,4-trimethylcyclohex-2-en-1-one
8-(4-hydroxyphenyl)-9-methyl-5,9-diazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),2(6),3,10,12-pentaen-7-one
C19H16N2O2 (304.12117159999997)