NCBI Taxonomy: 4769
Saprolegnia (ncbi_taxid: 4769)
found 23 associated metabolites at genus taxonomy rank level.
Ancestor: Saprolegniaceae
Child Taxonomies: Saprolegnia ferax, Saprolegnia monoica, Saprolegnia mixta, Saprolegnia delica, Saprolegnia bulbosa, Saprolegnia furcata, Saprolegnia turfosa, Saprolegnia oliviae, Saprolegnia diclina, Saprolegnia racemosa, Saprolegnia salmonis, Saprolegnia hypogyna, Saprolegnia torulosa, Saprolegnia unispora, Saprolegnia truncata, Saprolegnia lapponica, Saprolegnia milanezii, Saprolegnia australis, Saprolegnia glomerata, Saprolegnia litoralis, Saprolegnia cf. ferax, Saprolegnia anomalies, Saprolegnia maragheica, Saprolegnia multispora, Saprolegnia megasperma, Saprolegnia parasitica, Saprolegnia anisospora, Saprolegnia eccentrica, Saprolegnia monilifera, Saprolegnia polymorpha, Saprolegnia terrestris, Saprolegnia asterophora, Saprolegnia aenigmatica, Saprolegnia subterranea, Saprolegnia longicaulis, Saprolegnia semihypogyna, Saprolegnia blelhamensis, unclassified Saprolegnia
Lanosterol
Lanosterol, also known as lanosterin, belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. Thus, lanosterol is considered to be a sterol lipid molecule. Lanosterol is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Lanosterol is biochemically synthesized starting from acetyl-CoA by the HMG-CoA reductase pathway. The critical step is the enzymatic conversion of the acyclic terpene squalene to the polycylic lanosterol via 2,3-squalene oxide. Constituent of wool fat used e.g. as chewing-gum softenerand is) also from yeast COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
15(S)-HPETE
15(S)-hydroperoxyeicosatetraenoic acid (15(S)-HPETE) is the corresponding hydroperoxide of 15(S)-HETE and undergoes homolytic decomposition to the DNA-reactive bifunctional electrophile 4-oxo-2(E)-nonenal, a precursor of heptanone-etheno-2-deoxyguanosine. Reactive oxygen species convert the omega-6 polyunsaturated fatty acid arachidonic acid into (15-HPETE); vitamin C mediates 15(S)-HPETE decomposition. 15(S)-HPETE initiates apoptosis in vascular smooth muscle cells. 15(S)-HPETE is a lipoxygenase metabolite that affects the expression of cell adhesion molecules (CAMs) involved in the adhesion of leukocytes and/or the accumulation of leukocytes in the vascular endothelium, these being the initial events in endothelial cell injury. 15(S)-HPETE induces a loss of cardiomyocytes membrane integrity. 15-(S)HPETE is a hydroperoxide that enhances the activity of the enzymes lipoxygenase [EC 1.13.11.12] and Na+, K+-ATPase [EC 3.6.3.9] of brain microvessels. Lipoxygenase(s) and Na+-K+-ATPase of brain microvessels may play a significant role in the occurrence of ischemic brain edema. (PMID: 15964853, 15723435, 8655602, 8595608, 2662983). D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
15-Hydroperoxyicosa-5,8,11,13-tetraenoic acid
Lanosterin
A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Lanster
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS