NCBI Taxonomy: 2763534
Carex subgen. Vignea (ncbi_taxid: 2763534)
found 53 associated metabolites at subgenus taxonomy rank level.
Ancestor: Carex
Child Taxonomies: Carex feta, Carex alta, Carex alma, Carex hebes, Carex furva, Carex curta, Carex alata, Carex densa, Carex davyi, Carex opaca, Carex arcta, Carex fissa, Carex paxii, Carex pansa, Carex gibba, Carex secta, Carex rosea, Carex fossa, Carex divisa, Carex fracta, Carex repens, Carex adusta, Carex hoodii, Carex kirkii, Carex bebbii, Carex ebenea, Carex tenera, Carex foenea, Carex dioica, Carex illota, Carex longii, Carex ruthii, Carex seorsa, Carex tincta, Carex vexans, Carex gayana, Carex omiana, Carex pairae, Carex exilis, Carex marina, Carex ursina, Carex remota, Carex enokii, Carex diandra, Carex iljinii, Carex praecox, Carex jonesii, Carex stipata, Carex abrupta, Carex siccata, Carex brevior, Carex foetida, Carex vulpina, Carex otrubae, Carex divulsa, Carex leersii, Carex spicata, Carex curaica, Carex magacis, Carex hyalina, Carex integra, Carex maackii, Carex molesta, Carex planata, Carex prairea, Carex otomana, Carex ownbeyi, Carex silicea, Carex sororia, Carex enervis, Carex purdiei, Carex gravida, Carex nervina, Carex reichei, Carex inversa, Carex radiata, Carex interior, Carex glareosa, Carex diastena, Carex colensoi, Carex muricata, Carex cumulata, Carex elongata, Carex cusickii, Carex appressa, Carex loliacea, Carex leporina, Carex maritima, Carex disticha, Carex normalis, Carex orizabae, Carex ozarkana, Carex petasata, Carex potosina, Carex scoparia, Carex physodes, Carex subfusca, Carex socialis, Carex sterilis, Carex texensis, Carex wootonii, Carex austrina, Carex nubigena, Carex simulata, Carex conferta, Carex rupicola, Carex disperma, Carex kaloides, Carex muelleri, Carex projecta, Carex colchica, Carex deweyana, Carex arenaria, Carex echinata, Carex egorovae, Carex feddeana, Carex bohemica, Carex kobomugi, Carex iraqensis, Carex bromoides, Carex parallela, Carex brizoides, Carex resectans, Carex bolanderi, Carex echinodes, Carex vallicola, Carex gracilior, Carex harfordii, Carex xerantica, Carex vernacula, Carex oronensis, Carex aggregata, Carex annectens, Carex atlantica, Carex conjuncta, Carex praticola, Carex douglasii, Carex hookerana, Carex leptopoda, Carex specifica, Carex straminea, Carex suberecta, Carex tahoensis, Carex proposita, Carex declinata, Carex wiegandii, Carex sagaensis, Carex arenicola, Carex balfourii, Carex bracteosa, Carex toreadora, Carex sectoides, Carex trisperma, Carex lapponica, Carex canescens, Carex arkansana, Carex hypoleucos, Carex nemurensis, Carex argyrantha, Carex davalliana, Carex crawfordii, Carex lithophila, Carex paniculata, Carex macloviana, Carex bonplandii, Carex peucophila, Carex lachenalii, Carex festucacea, Carex haydeniana, Carex mariposana, Carex mandoniana, Carex reniformis, Carex sartwellii, Carex laevissima, Carex shinnersii, Carex hypsipedos, Carex stenoptila, Carex mesochorea, Carex pleioneura, Carex neurocarpa, Carex neurophora, Carex perdentata, Carex pterocarpa, Carex tumulicola, Carex michoacana, Carex perglobosa, Carex retroflexa, Carex reptabunda, Carex incomitata, Carex crus-corvi, Carex subdivulsa, Carex sajanensis, Carex tenuiflora, Carex uruguensis, Carex vulpinaris, Carex ecuadorica, Carex accrescens, Carex duriuscula, Carex bicknellii, Carex bonanzensis, Carex traiziscana, Carex stenophylla, Carex macrorrhiza, Carex wallichiana, Carex cristatella, Carex canariensis, Carex satsumensis, Carex heleonastes, Carex egglestonii, Carex brunnescens, Carex hormathodes, Carex leporinella, Carex rochebrunei, Carex vulpinoidea, Carex alopecoidea, Carex bonariensis, Carex pachystylis, Carex roraimensis, Carex laeviculmis, Carex marianensis, Carex rochebrunii, Carex leiorhyncha, Carex unisexualis, Carex appalachica, Carex cephaloidea, Carex decomposita, Carex subfuegiana, Carex subphysodes, Carex tenuiculmis, Carex trachycarpa, Carex tribuloides, Carex yamatsutana, Carex giovanniana, Carex firmicaulis, Carex arctiformis, Carex arapahoensis, Carex athrostachya, Carex macrocephala, Carex constanceana, Carex chordorrhiza, Carex multicostata, Carex occidentalis, Carex pachystachya, Carex phaeocephala, Carex praegracilis, Carex oklahomensis, Carex subbracteata, Carex praeceptorum, Carex tetrastachya, Carex unilateralis, Carex triangularis, Carex pycnostachya, Carex remotiuscula, Carex tereticaulis, Carex cephalophora, Carex trachycystis, Carex brongniartii, Carex leavenworthii, Carex albolutescens, Carex appropinquata, Carex infirminervia, Carex missouriensis, Carex molestiformis, Carex chihuahuensis, Carex pseudocuraica, Carex incurviformis, Carex sychnocephala, Carex sparganioides, Carex erythrorrhiza, Carex subebracteata, Carex pseudofoetida, Carex laevivaginata, Carex muehlenbergii, Carex lucennoiberica, Carex kreczetoviczii, Carex pseudololiacea, Carex ovatispiculata, Carex muskingumensis, Carex straminiformis, Carex pseudobrizoides, Carex waponahkikensis, Carex pseudomacloviana, Carex merritt-fernaldii, Carex x pseudoaxillaris, Carex cf. gravida Hipp 498, Carex cf. echinata KSRB 051, Carex remota x Carex vulpina, Carex cf. macrorrhiza MH-2020, Carex cf. cristatella JAG 0457, Carex cf. microptera 'Pinaleno', Carex cf. brevior Reznicek 10497, Carex cf. microptera Reznicek 10303, Carex cf. lagunensis Gonzalez et al. 4482
Luteolin
Luteolin is a naturally occurring flavonoid. (PMID:17168665). The flavonoids are polyphenolic compounds found as integral components of the human diet. They are universally present as constituents of flowering plants, particularly of food plants. The flavonoids are phenyl substituted chromones (benzopyran derivatives) consisting of a 15-carbon basic skeleton (C6-C3-C6), composed of a chroman (C6-C3) nucleus (the benzo ring A and the heterocyclic ring C), also shared by the tocopherols, with a phenyl (the aromatic ring B) substitution usually at the 2-position. Different substitutions can typically occur in the rings, A and B. Several plants and spices containing flavonoid derivatives have found application as disease preventive and therapeutic agents in traditional medicine in Asia for thousands of years. The selection of a particular food plant, plant tissue or herb for its potential health benefits appears to mirror its flavonoid composition. The much lower risk of colon, prostate and breast cancers in Asians, who consume more vegetables, fruits and tea than populations in the Western hemisphere do, raises the question of whether flavonoid components mediate the protective effects of diets rich in these foodstuffs by acting as natural chemopreventive and anticancer agents. An impressive body of information exists on the antitumoral action of plant flavonoids. In vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. Furthermore, some studies have reported the impairment of in vivo angiogenesis by dietary flavonoids. Experimental animal studies indicate that certain dietary flavonoids possess antitumoral activity. The hydroxylation pattern of the B ring of the flavones and flavonols, such as luteolin seems to critically influence their activities, especially the inhibition of protein kinase activity and antiproliferation. The different mechanisms underlying the potential anticancer action of plant flavonoids await further elucidation. Certain dietary flavonols and flavones targeting cell surface signal transduction enzymes, such as protein tyrosine and focal adhesion kinases, and the processes of angiogenesis appear to be promising candidates as anticancer agents. Further in vivo studies of these bioactive constituents is deemed necessary in order to develop flavonoid-based anticancer strategies. In view of the increasing interest in the association between dietary flavonoids and cancer initiation and progression, this important field is likely to witness expanded effort and to attract and stimulate further vigorous investigations (PMID:16097445). Luteolin is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. It has a role as an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, a plant metabolite, a nephroprotective agent, an angiogenesis inhibitor, a c-Jun N-terminal kinase inhibitor, an anti-inflammatory agent, an apoptosis inducer, a radical scavenger and an immunomodulator. It is a 3-hydroxyflavonoid and a tetrahydroxyflavone. It is a conjugate acid of a luteolin-7-olate. Luteolin is a natural product found in Verbascum lychnitis, Carex fraseriana, and other organisms with data available. Luteolin is a naturally-occurring flavonoid, with potential anti-oxidant, anti-inflammatory, apoptosis-inducing and chemopreventive activities. Upon administration, luteolin scavenges free radicals, protects cells from reactive oxygen species (ROS)-induced damage and induces direct cell cycle arrest and apoptosis in tumor cells. This inhibits tumor cell proliferation and suppresses metastasis. 5,7,3,4-tetrahydroxy-flavone, one of the FLAVONES. See also: Chamomile (part of); Cannabis sativa subsp. indica top (part of); Fenugreek seed (part of). A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. Flavone v. widespread in plant world; found especies in celery, peppermint, rosemary, thyme and Queen Annes Lace leaves (wild carrot). Potential nutriceutical. Luteolin is found in many foods, some of which are soy bean, ginger, abalone, and swiss chard. Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 361; CONFIDENCE confident structure CONFIDENCE standard compound; INTERNAL_ID 48 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
sulfurein
Sulfuretin is a member of 1-benzofurans. Sulfuretin is a natural product found in Calanticaria bicolor, Dipteryx lacunifera, and other organisms with data available. Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2]. Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
epsilon-Viniferin
(7E,7R,8R)-epsilon-Viniferin is found in alcoholic beverages. (7E,7R,8R)-epsilon-Viniferin is isolated from leaves of wine grape (Vitis vinifera) infected with Botrytis cinere
Tricin
[Raw Data] CBA24_Tricin_neg_50eV_1-6_01_1424.txt [Raw Data] CBA24_Tricin_pos_50eV_1-6_01_1397.txt [Raw Data] CBA24_Tricin_neg_10eV_1-6_01_1368.txt [Raw Data] CBA24_Tricin_pos_40eV_1-6_01_1396.txt [Raw Data] CBA24_Tricin_pos_20eV_1-6_01_1394.txt [Raw Data] CBA24_Tricin_neg_30eV_1-6_01_1422.txt [Raw Data] CBA24_Tricin_neg_20eV_1-6_01_1421.txt [Raw Data] CBA24_Tricin_pos_10eV_1-6_01_1357.txt [Raw Data] CBA24_Tricin_pos_30eV_1-6_01_1488.txt [Raw Data] CBA24_Tricin_neg_40eV_1-6_01_1423.txt Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3]. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].
cis-Miyabenol C
Constituent of the fruit of Foeniculum vulgare (fennel). cis-Miyabenol C is found in fennel and herbs and spices. cis-Miyabenol C is found in fennel. cis-Miyabenol C is a constituent of the fruit of Foeniculum vulgare (fennel).
Sulfuretin
Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2]. Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
Viniferin
Luteolin
Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.976 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.975 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.968 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.971 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
sulfurein
Sulfuretin is a member of 1-benzofurans. Sulfuretin is a natural product found in Calanticaria bicolor, Dipteryx lacunifera, and other organisms with data available. Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2]. Sulfuretin inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM[2].
Tricin
3,5-di-O-methyltricetin is the 3,5-di-O-methyl ether of tricetin. Known commonly as tricin, it is a constituent of rice bran and has been found to potently inhibit colon cancer cell growth. It has a role as an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and a metabolite. It is a trihydroxyflavone, a dimethoxyflavone and a member of 3-methoxyflavones. It is functionally related to a tricetin. It is a conjugate acid of a 3,5-di-O-methyltricetin(1-). Tricin is a natural product found in Carex fraseriana, Smilax bracteata, and other organisms with data available. See also: Arnica montana Flower (part of); Elymus repens root (part of). The 3,5-di-O-methyl ether of tricetin. Known commonly as tricin, it is a constituent of rice bran and has been found to potently inhibit colon cancer cell growth. Isolated from Triticum dicoccum (emmer). Tricin 5-diglucoside is found in wheat and cereals and cereal products. From leaves of Oryza sativa (rice). 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one, also known as 3,5-O-dimethyltricetin or 5,7,4-trihydroxy-3,5-dimethoxy-flavone, is a member of the class of compounds known as 3-o-methylated flavonoids. 3-o-methylated flavonoids are flavonoids with methoxy groups attached to the C3 atom of the flavonoid backbone. Thus, 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one is considered to be a flavonoid lipid molecule. 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one can be synthesized from tricetin. 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one is also a parent compound for other transformation products, including but not limited to, tricin 7-O-glucoside, 4-O-beta-glucosyl-7-O-(6-O-sinapoylglucosyl)tricin, and tricin 7-O-(6-O-malonyl)-beta-D-glucopyranoside. 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one can be found in barley, common wheat, oat, and rice, which makes 5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4h-chromen-4-one a potential biomarker for the consumption of these food products. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3]. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[1][2][3].
miyabenol C
Cis-miyabenol c is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Cis-miyabenol c is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cis-miyabenol c can be found in fennel and herbs and spices, which makes cis-miyabenol c a potential biomarker for the consumption of these food products.
Epsilon-Viniferin
(-)-trans-epsilon-viniferin is a stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol. It has a role as a metabolite. It is a member of 1-benzofurans, a polyphenol and a stilbenoid. It is functionally related to a trans-resveratrol. It is an enantiomer of a (+)-trans-epsilon-viniferin. Epsilon-viniferin is a natural product found in Dipterocarpus grandiflorus, Dipterocarpus hasseltii, and other organisms with data available. A stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol.
cis-Miyabenol C
Cis-miyabenol c is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Cis-miyabenol c is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cis-miyabenol c can be found in fennel and herbs and spices, which makes cis-miyabenol c a potential biomarker for the consumption of these food products.