NCBI Taxonomy: 2743202
Annona spinescens (ncbi_taxid: 2743202)
found 80 associated metabolites at species taxonomy rank level.
Ancestor: Annona
Child Taxonomies: none taxonomy data.
(S)-Reticuline
C19H23NO4 (329.16269980000004)
(S)-Reticuline is an endogenous precursor of morphine (PMID: 15383669). (S)-Reticuline is a key intermediate in the synthesis of morphine, the major active metabolite of the opium poppy. "Endogenous morphine" has been long isolated and authenticated by mass spectrometry in trace amounts from animal- and human-specific tissue or fluids (PMID: 15874902). Human neuroblastoma cells (SH-SY5Y) were shown capable of synthesizing morphine as well. (S)-Reticuline undergoes a change of configuration at C-1 during its transformation into salutaridinol and thebaine. From thebaine, there is a bifurcate pathway leading to morphine proceeding via codeine or oripavine, in both plants and mammals (PMID 15937106). (S)-reticuline is the (S)-enantiomer of reticuline. It has a role as an EC 2.1.1.116 [3-hydroxy-N-methyl-(S)-coclaurine 4-O-methyltransferase] inhibitor. It is a conjugate base of a (S)-reticulinium(1+). It is an enantiomer of a (R)-reticuline. Reticuline is a natural product found in Fumaria capreolata, Berberis integerrima, and other organisms with data available. See also: Peumus boldus leaf (part of). Alkaloid from Papaver somniferum (opium poppy) and Annona reticulata (custard apple) The (S)-enantiomer of reticuline.
Liriodenine
Liriodenine is an oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities. It has a role as a metabolite, an antineoplastic agent, an antimicrobial agent, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an antifungal agent. It is a cyclic ketone, an oxacycle, an organic heteropentacyclic compound, an alkaloid antibiotic and an oxoaporphine alkaloid. It is functionally related to an aporphine. Liriodenine is a natural product found in Magnolia mexicana, Annona purpurea, and other organisms with data available. Liriodenine, also known as oxoushinsunine or micheline b, is a member of the class of compounds known as aporphines. Aporphines are quinoline alkaloids containing the dibenzo[de,g]quinoline ring system or a dehydrogenated derivative thereof. Liriodenine is practically insoluble (in water) and a strong basic compound (based on its pKa). Liriodenine can be found in cherimoya and custard apple, which makes liriodenine a potential biomarker for the consumption of these food products. Liriodenine is a bio-active isolate of the Chinese medicinal herb Zanthoxylum nitidum .
Anonaine
Alkaloid from Annona muricata (soursop) and Nelumbo nucifera (East India lotus). Anonaine is found in many foods, some of which are sugar apple, sacred lotus, fruits, and custard apple. Anonaine is found in cherimoya. Anonaine is an alkaloid from Annona muricata (soursop) and Nelumbo nucifera (East India lotus
Bullatanocin
12,15-cis-Sylvaticin is found in alcoholic beverages. 12,15-cis-Sylvaticin is isolated from Rollinia mucosa (biriba).
Asitribin
Asiminacin is found in fruits. Asiminacin is a constituent of Asimina triloba (pawpaw) and Annona squamosa (sugar apple). Constituent of the seeds of Asimina triloba (pawpaw). Asitribin is found in fruits.
12,15-cis-Squamostatin A
Constituent of the seeds of Annona atemoya (custard apple). Cytotoxic. 12,15-cis-Squamostatin A is found in fruits. Squamostatin B is found in fruits. Squamostatin B is a constituent of Annona squamosa (sugar apple).
Squamocin L
Isodesacetyluvaricin is found in fruits. Isodesacetyluvaricin is isolated from Annona species.
Motrilin
Asiminecin is found in fruits. Asiminecin is a constituent of Asimina triloba (pawpaw). Constituent of Asimina triloba (pawpaw). Asiminecin is found in fruits.
Rollitacin
Purpurediolin is found in beverages. Purpurediolin is a constituent of the seeds of Annona purpurea (soncoya) Constituent of the seeds of Annona purpurea (soncoya). Purpurediolin is found in beverages and fruits.
Liriodenine
Liriodenine is an oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities. It has a role as a metabolite, an antineoplastic agent, an antimicrobial agent, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an antifungal agent. It is a cyclic ketone, an oxacycle, an organic heteropentacyclic compound, an alkaloid antibiotic and an oxoaporphine alkaloid. It is functionally related to an aporphine. Liriodenine is a natural product found in Magnolia mexicana, Annona purpurea, and other organisms with data available. An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities.
anonaine
An aporphine alkaloid that exhibits anti-cancer, trypanocidal and antiplasmodial activites.
Asitribin
Squamocin L
Rollitacin
12,15-cis-Squamostatin A
(5s)-3-[(13r)-13-hydroxy-13-[(2r,2'r,5r,5's)-5'-[(1r,5r,6r)-1,5,6-trihydroxyundecyl]-[2,2'-bioxolan]-5-yl]tridecyl]-5-methyl-5h-furan-2-one
(9s)-5,15-dimethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-4,16-diol
(9s)-5,15-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-4,16-diol
C19H21NO4 (327.14705060000006)
(5s)-3-[(13r)-13-[(2s,2's,5r,5's)-5'-[(1s)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
(5s)-3-[(2r)-9-[(2r,5s)-5-[(1s,4r)-1,4-dihydroxy-4-[(2r,5r)-5-[(1r)-1-hydroxyundecyl]oxolan-2-yl]butyl]oxolan-2-yl]-2-hydroxynonyl]-5-methyl-5h-furan-2-one
(5s)-3-[(11r)-11-[(2s,2'r,5s,5'r)-5'-[(1r,5r)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-11-hydroxyundecyl]-5-methyl-5h-furan-2-one
(12bs)-10,11-dimethoxy-7,8,12b,13-tetrahydro-5h-6-azatetraphene-2,3-diol
C19H21NO4 (327.14705060000006)
(5s)-3-[(13s)-13-hydroxy-13-[(2s,2's,5s,5'r)-5'-[(1s)-1,5,6-trihydroxyundecyl]-[2,2'-bioxolan]-5-yl]tridecyl]-5-methyl-5h-furan-2-one
10',11'-dimethoxy-5'-azaspiro[cyclohexane-1,2'-tricyclo[6.3.1.0⁴,¹²]dodecane]-1'(11'),2,5,8'(12'),9'-pentaen-4-one
C18H19NO3 (297.13648639999997)
3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1,6,8(20),14,16,18-hexaen-13-ol
(5r)-3-[(2r)-9-[(2r,5s)-5-[(1s,4r)-1,4-dihydroxy-4-[(2r,5r)-5-[(1r)-1-hydroxyundecyl]oxolan-2-yl]butyl]oxolan-2-yl]-2-hydroxynonyl]-5-methyl-5h-furan-2-one
methyl (2e)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate
(5r)-3-[(13s)-13-[(2s,2's,5s,5's)-5'-[(1r,5s)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
(5r)-3-[(13s)-13-[(2s,2'r,5r,5's)-5'-[(1s,5r)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
(5s)-3-[(11r)-11-[(2s,2's,5r,5's)-5'-[(1s)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-11-hydroxyundecyl]-5-methyl-5h-furan-2-one
3-{13-hydroxy-13-[5'-(1,5,6-trihydroxyundecyl)-[2,2'-bioxolan]-5-yl]tridecyl}-5-methyl-5h-furan-2-one
(5r)-3-[(13r)-13-[(2r,2's,5s,5'r)-5'-[(1r,6s)-1,6-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
3-{13-hydroxy-13-[5'-(1-hydroxyundecyl)-[2,2'-bioxolan]-5-yl]tridecyl}-5-methyl-5h-furan-2-one
(5s)-3-[(13r)-13-hydroxy-13-[(2r,2'r,5r,5'r)-5'-[(1s)-1-hydroxyundecyl]-[2,2'-bioxolan]-5-yl]tridecyl]-5-methyl-5h-furan-2-one
(5r)-3-{9-[(2r,5r)-5-[(1s,4r)-4-[(2r,5s)-5-[(1s,5s)-1,5-dihydroxyundecyl]oxolan-2-yl]-1,4-dihydroxybutyl]oxolan-2-yl]nonyl}-5-methyl-5h-furan-2-one
3-{13-[5'-(1,5-dihydroxyundecyl)-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl}-5-methyl-5h-furan-2-one
(5s)-3-[(13r)-13-[(2s,2's,5r,5's)-5'-[(1s)-1,6-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
(5s)-3-[(13s)-13-[(2r,2'r,5r,5'r)-5'-[(1s,5r)-1,5-dihydroxyundecyl]-[2,2'-bioxolan]-5-yl]-13-hydroxytridecyl]-5-methyl-5h-furan-2-one
(5s)-3-{9-[(2s,5r)-5-[(1r,4s)-4-[(2r,5r)-5-[(1s,5r)-1,5-dihydroxyundecyl]oxolan-2-yl]-1,4-dihydroxybutyl]oxolan-2-yl]nonyl}-5-methyl-5h-furan-2-one
(5r)-3-[(13r)-13-hydroxy-13-[(2r,2'r,5r,5'r)-5'-[(1r)-1-hydroxyundecyl]-[2,2'-bioxolan]-5-yl]tridecyl]-5-methyl-5h-furan-2-one
3-(9-{5-[(1r,4r)-4-[(2r,5r)-5-[(1s)-1,5-dihydroxyundecyl]oxolan-2-yl]-1,4-dihydroxybutyl]oxolan-2-yl}nonyl)-5-methyl-5h-furan-2-one
3-{11-hydroxy-11-[5'-(1-hydroxyundecyl)-[2,2'-bioxolan]-5-yl]undecyl}-5-methyl-5h-furan-2-one
(12s)-18-methoxy-5,7-dioxa-13-azapentacyclo[10.7.1.0²,¹⁰.0⁴,⁸.0¹⁶,²⁰]icosa-1(19),2,4(8),9,16(20),17-hexaen-19-ol
C18H17NO4 (311.11575220000003)