NCBI Taxonomy: 2013
Nocardiopsis (ncbi_taxid: 2013)
found 459 associated metabolites at genus taxonomy rank level.
Ancestor: Nocardiopsaceae
Child Taxonomies: Nocardiopsis alba, Nocardiopsis listeri, Nocardiopsis prasina, Nocardiopsis gilva, Nocardiopsis rosea, Nocardiopsis salina, Nocardiopsis terrae, Nocardiopsis oceani, Nocardiopsis potens, Nocardiopsis lucentensis, Nocardiopsis tropica, Nocardiopsis akebiae, Nocardiopsis deserti, Nocardiopsis suaedae, Nocardiopsis mwathae, Nocardiopsis coralli, Nocardiopsis dassonvillei, Nocardiopsis exhalans, environmental samples, Nocardiopsis composta, Nocardiopsis aegyptia, Nocardiopsis trehalosi, Nocardiopsis sediminis, Nocardiopsis eucommiae, Nocardiopsis halophila, Nocardiopsis mangrovei, Nocardiopsis flavescens, Nocardiopsis akesuensis, Nocardiopsis metallicus, Nocardiopsis alborubida, Nocardiopsis rhodophaea, Nocardiopsis fildesensis, Nocardiopsis algeriensis, Nocardiopsis valliformis, Nocardiopsis viridoflava, Nocardiopsis kunsanensis, Nocardiopsis endophytica, Nocardiopsis tangguensis, Nocardiopsis alkaliphila, Nocardiopsis nikkonensis, Nocardiopsis nanhaiensis, Nocardiopsis synnemataformans, Nocardiopsis sinuspersici, Nocardiopsis umidischolae, Nocardiopsis coralliicola, Nocardiopsis halotolerans, Nocardiopsis changdeensis, Nocardiopsis ansamitocini, unclassified Nocardiopsis, Nocardiopsis benisuefensis, Nocardiopsis quinghaiensis, Nocardiopsis ganjiahuensis, Nocardiopsis xinjiangensis, Nocardiopsis chromatogenes, Nocardiopsis baichengensis, Nocardiopsis yanglingensis, Nocardiopsis rhizosphaerae, Nocardiopsis synnemasporogenes, Candidatus Nocardiopsis merdipullorum
Novobiocin
Novobiocin is only found in individuals that have used or taken this drug. It is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) [PubChem]Novobiocin is an aminocoumarin. Aminocoumarins are very potent inhibitors of bacterial DNA gyrase and work by inhibiting the GyrB subunit of the enzyme involved in energy tranduction. Novobiocin as well as the other aminocoumarin antibiotics act as competitive inhibitors of the ATPase reaction catalysed by GyrB. D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic CONFIDENCE standard compound; INTERNAL_ID 1168 CONFIDENCE standard compound; INTERNAL_ID 1167 Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity[1][2][3][4][6].
K-252c
D004791 - Enzyme Inhibitors
6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one
D004791 - Enzyme Inhibitors
Novobiocin
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents A coumarin-derived antibiotic obtained from Streptomyces niveus. C254 - Anti-Infective Agent > C258 - Antibiotic Origin: Microbe, Coumarins Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity[1][2][3][4][6].
(2s)-2-({[(3r,4e)-1-[(2s)-6-carbamimidamido-2-[(1-hydroxy-3-methylbut-2-en-1-ylidene)amino]hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoic acid
(2s,4s,5s,6s)-4,5-dihydroxy-6-[3-(c-hydroxycarbonimidoylmethyl)-4-methoxyindol-1-yl]oxane-2-carboximidic acid
C17H21N3O6 (363.14302860000004)
3-[(4-hydroxyphenyl)methylidene]-5-methoxy-6-[(4-methoxyphenyl)methylidene]-1-methylpyrazin-2-one
C21H20N2O4 (364.14230000000003)
3,13,17,27-tetramethyl-1,15-diazacyclooctacosa-3,5,7,9,11,17,19,21,23,25-decaene-2,16-dione
C30H38N2O2 (458.29331279999997)
(7s)-4-(1-hydroxy-3-oxopentyl)-2,4,17,19-tetramethyl-5,26-dioxa-11-azatricyclo[21.2.1.0⁷,¹¹]hexacosa-13,19-diene-6,12,18-trione
(2r,3r,4s,5s,6r)-2-{[(2r,3r,4s,5s,6r)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
methyl 2-{3',4,9-trihydroxy-6'-methyl-4',5,10-trioxo-3,4-dihydrospiro[naphtho[2,3-c]pyran-1,2'-oxan]-3-yl}acetate
3-[(4-hydroxyphenyl)methyl]-6,12,15,18-tetraisopropyl-9-(2-methylpropyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
(2s,3r,4s)-4-[(2s,5r,7s,8r,9r,10r)-2-[(2s,2'r,3's,4r,5r,5'r)-5'-[(2s,3s,5s)-2-hydroxy-5-[(1r)-1-hydroxypropyl]-3,5-dimethyloxolan-2-yl]-4-{[(2s,5s,6r)-5-methoxy-6-methyloxan-2-yl]oxy}-2,3'-dimethyl-[2,2'-bioxolan]-5-yl]-9-methoxy-8,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoic acid
3,4,4'-trihydroxy-6-methyl-10'-(2-oxopropyl)-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-3',5',7'-triene-2',9',13'-trione
C23H24O10 (460.13694039999996)
(3s,6s,9s,12s,15s,18s)-3-[(2s)-butan-2-yl]-6,18-bis(1h-indol-3-ylmethyl)-12-isopropyl-9-methyl-15-(2-methylpropyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
(10s,13s)-10-[(2s)-butan-2-yl]-13-(hydroxymethyl)-9-methyl-5-(2-methylbut-3-en-2-yl)-3,9,12-triazatricyclo[6.6.1.0⁴,¹⁵]pentadeca-1,4,6,8(15),11-pentaen-11-ol
C23H33N3O2 (383.25726380000003)
10-[(3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl)oxy]-20-({2,4-dihydroxy-6-[2-({4-hydroxy-5-[(5-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy]-4,6-dimethyloxan-2-yl}oxy)-3-methoxypropyl]-3,5-dimethyloxan-2-yl}(hydroxy)methyl)-17-hydroxy-18-methoxy-3,5,7,9,13-pentamethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
(3e,5e,7e,9r,10r,11e,13e,17s,18s,20s)-10-{[(2r,3s,4s,5r,6s)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-20-[(r)-[(2r,3r,4s,5r,6r)-2,4-dihydroxy-6-[(2r)-2-{[(2r,4s,5s,6s)-4-hydroxy-5-{[(2s,4r,5r,6r)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,6-dimethyloxan-2-yl]oxy}-3-methoxypropyl]-3,5-dimethyloxan-2-yl](hydroxy)methyl]-17-hydroxy-18-methoxy-3,5,9,13-tetramethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
(2e,6r,7e,9s)-6-(2-hydroxypropan-2-yl)-3,9-dimethylcyclodeca-2,7-dien-1-one
(10'r,12'r,15'r)-1',6',9',10'-tetrahydroxy-12'-methyl-3h-13'-oxaspiro[pyran-2,16'-tetracyclo[7.6.1.0²,⁷.0¹⁰,¹⁵]hexadecane]-2',4',6'-triene-6,8',14'-trione
1-(5-amino-1h-imidazol-4-yl)-8-methylnonan-1-one
C13H23N3O (237.18410279999998)
4-(2-{5'-[2-hydroxy-5-(1-hydroxypropyl)-3,5-dimethyloxolan-2-yl]-4-[(5-methoxy-6-methyloxan-2-yl)oxy]-2,3'-dimethyl-[2,2'-bioxolan]-5-yl}-9-methoxy-8,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoic acid
(2s)-2-({[(3r,4e)-1-[(2s)-6-carbamimidamido-2-[(1-hydroxy-3-methylbutylidene)amino]hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-3-(1h-indol-3-yl)propanoic acid
C31H45N7O5 (595.3481999999999)
(1s,4s,12s,14s,17r,25r)-5,25-dimethyl-12-(3-methylbut-2-en-1-yl)-3,5,16,18-tetraazaheptacyclo[14.10.0.0³,¹⁴.0⁴,¹².0⁶,¹¹.0¹⁷,²⁵.0¹⁹,²⁴]hexacosa-6,8,10,19,21,23-hexaene-2,15-dione
C29H32N4O2 (468.25251319999995)
(3z,5e,7e,9r,10r,11e,13e,17s,18s,20s)-10-{[(2r,3s,4s,5r,6s)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-20-[(r)-[(2r,3r,4s,5r,6r)-2,4-dihydroxy-6-[(2r)-2-{[(2r,4s,5s,6s)-4-hydroxy-5-{[(2s,4r,5r,6r)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,6-dimethyloxan-2-yl]oxy}-3-methoxypropyl]-3,5-dimethyloxan-2-yl](hydroxy)methyl]-17-hydroxy-18-methoxy-3,5,7,9,13-pentamethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
6-[(2e)-but-2-en-2-yl]-3-(2-methylpropyl)pyran-2-one
2-(4-hydroxyphenyl)ethyl (3e)-4-phenylbut-3-enoate
3-(1-hydroxyethyl)-6-[(2e)-pent-2-en-2-yl]pyran-2-one
2-(7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)-4-hydroxycyclopentane-1-carboxylic acid
C28H43NO7 (505.30393680000003)
(2s)-2-({[(3r,4e)-1-[(2s)-6-carbamimidamido-2-[(1-hydroxy-3-methylbutylidene)amino]hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoic acid
2-[4-(hydroxymethyl)-4,5-dihydro-1,3-oxazol-2-yl]phenol
16-hydroxy-3,13,17,19,29-pentamethyl-1,15-diazacyclotriaconta-3,5,7,9,11,15,17,19,21,23,25,27-dodecaen-2-one
3,4'-dihydroxy-6-methyl-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-1'(10'),3',5',7'-tetraene-2',4,9',13'-tetrone
(1s,2e,6s,7e,9r)-9-(2-hydroxypropan-2-yl)-2,6-dimethylcyclodeca-2,7-dien-1-ol
(1s,2e,4e,6s,7r,8s,11r,12e,14e,16r,17r,18r,19s)-8-{[(2s,3r,4r,5r)-3-amino-4,5-dihydroxyoxan-2-yl]oxy}-7,18-dihydroxy-7,19-dimethyl-21-azatetracyclo[14.6.0.0⁶,¹¹.0¹⁷,²¹]docosa-2,4,9,12,14-pentaen-22-one
C28H38N2O7 (514.2678877999999)
2-{[(1-{6-carbamimidamido-2-[(1-hydroxy-3-methylbut-2-en-1-ylidene)amino]hexanoyl}-4-ethylidene-3-methylpyrrolidin-2-yl)(hydroxy)methylidene]amino}-4-methylpentanoic acid
(1r,2r,4r)-2-[(2s,8r,9s,11r,13s,15s,16s)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]-4-hydroxycyclopentane-1-carboxylic acid
C28H43NO7 (505.30393680000003)
(2s)-2-({[(2s,3r,4z)-1-[(2s)-6-carbamimidamido-2-{[hydroxy(phenyl)methylidene]amino}hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoic acid
(3e,9e,11z,13z,15s,19e,21e,23e,25e,27z,29z,31s)-3,7,15,19,23,31-hexamethyl-1,17-diazacyclodotriaconta-1,3,5,7,9,11,13,17,19,21,23,25,27,29-tetradecaene-2,18-diol
methyl (15s,16r,18r)-3,16-dihydroxy-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),3,7(27),8(13),9,11,20(25),21,23-decaene-16-carboxylate
C27H21N3O5 (467.14811360000004)
(3z,6z)-3-[(4-hydroxyphenyl)methylidene]-5-methoxy-6-[(4-methoxyphenyl)methylidene]-1-methylpyrazin-2-one
C21H20N2O4 (364.14230000000003)
(8r)-1-(5-amino-1h-imidazol-4-yl)-8-methyldecan-1-one
(2s,4ar,4bs,6s,6as,8s,10ar,10bs,11s,12as)-6,11-dihydroxy-2,4b,7,7,10a,12a-hexamethyl-12-methylidene-1,4-dioxo-decahydrophenanthro[1,2-c]pyran-8-yl acetate
5-(1,2-dihydroxy-2-methylpentyl)-3,5-dimethyloxolan-2-one
2-[(2-{[(14s,17e,31s)-17-ethylidene-12,15,22,29,36,39-hexahydroxy-14-[(1r)-1-hydroxyethyl]-20,31-dimethyl-38,41-dimethylidene-19,43-dioxa-9,26,33-trithia-3,13,16,23,30,37,40,45,46,47,48,49-dodecaazaheptacyclo[40.2.1.1⁸,¹¹.1¹⁸,²¹.1²⁵,²⁸.1³²,³⁵.0²,⁷]nonatetraconta-1(44),2,4,6,8(49),10,12,15,18(48),20,22,25(47),27,29,32(46),34,36,39,42(45)-nonadecaen-4-yl]formamido}-1-hydroxyprop-2-en-1-ylidene)amino]-n-(2-oxopropyl)prop-2-enimidic acid
C50H47N15O13S3 (1161.2639772000002)
9-(2-hydroxypropan-2-yl)-2,6-dimethylcyclodeca-2,7-dien-1-ol
(13s)-13-(hydroxymethyl)-9-methyl-5-(2-methylbut-3-en-2-yl)-10-(sec-butyl)-3,9,12-triazatricyclo[6.6.1.0⁴,¹⁵]pentadeca-1,4,6,8(15),11-pentaen-11-ol
C23H33N3O2 (383.25726380000003)
(2r,3r,4s,6r,11'r,15'r)-3,4,4'-trihydroxy-6-methyl-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-1'(10'),3',5',7'-tetraene-2',9',13'-trione
3,8,10,11-tetrahydroxy-2-(4-hydroxy-6-oxopyran-2-yl)-1-methyltetracene-5,12-dione
4-(1,3-dihydroxypentyl)-2,4,18,20-tetramethyl-5,27-dioxa-12-azatricyclo[22.2.1.0⁷,¹²]heptacosa-14,20-diene-6,13,19-trione
(2s)-2-({[(2s,3r,4e)-1-[(2s)-6-carbamimidamido-2-[(1-hydroxy-3-methylbutylidene)amino]hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-3-(1h-indol-3-yl)propanoic acid
C31H45N7O5 (595.3481999999999)
13-(hydroxymethyl)-10-isopropyl-9-methyl-5-(2-methylbut-3-en-2-yl)-3,9,12-triazatricyclo[6.6.1.0⁴,¹⁵]pentadeca-1,4,6,8(15),11-pentaen-11-ol
n-[(2r,3r,4s,5s,6s)-2-{[(5r,6r,9s,13r)-5,13-diethyl-14-hydroxy-9-methyl-1-azacyclotetradec-1(14)-en-6-yl]oxy}-3,5-dihydroxy-6-methyloxan-4-yl]ethanimidic acid
C26H48N2O6 (484.35121879999997)
(3r,5r)-5-(1,2-dihydroxy-2-methylpentyl)-3,5-dimethyloxolan-2-one
1,6-dihydroxy-5-oxo-5h-5λ⁵-phenazin-5-ylium-10-olate
2-(6-hydroxy-5-methylheptyl)-6-methoxy-3,5-dimethylpyran-4-one
2-hydroxy-1,7-dimethoxy-4,6,11-trioxo-3-propanoyl-4a,12-dihydro-1h-5-oxatetracene-12a-carboxylic acid
1,3,8,11-tetrahydroxy-9-(4-hydroxy-6-oxopyran-2-yl)-10-methyltetracene-5,12-dione
(3z,9r,10r,11z,13e,15e,17z,19z,21s)-7,21-dimethyl-1-azacyclodocosa-1,3,5,7,11,13,15,17,19-nonaene-2,9,10-triol
6-[(2e)-4-hydroxypent-2-en-2-yl]-3-methylpyran-2-one
(1'r,3's,7's,8r,12'r)-9,12'-dihydroxy-4,4,4',4',12',14'-hexamethyl-13'-oxo-9',14'-diazaspiro[[1,4]dioxepino[2,3-g]indole-8,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecan]-9'-ium-9'-olate
C28H35N3O6 (509.25257300000004)
4-methoxy-3,5-dimethyl-6-(5-methylhexyl)pyran-2-one
2-({[1-(6-carbamimidamido-2-{[hydroxy(phenyl)methylidene]amino}hexanoyl)-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoic acid
(1'r,3's,7's,8r,12's)-9-hydroxy-4,4,4',4',12',14'-hexamethyl-9',14'-diazaspiro[[1,4]dioxepino[2,3-g]indole-8,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecan]-13'-one
C28H35N3O4 (477.26274300000006)
(3e,5e,7e,9z,11z,13s,21e,23e,25z,27z,29s)-3,13,17,19,29-pentamethyl-1,15-diazacyclotriaconta-1,3,5,7,9,11,15,17,19,21,23,25,27-tridecaene-2,16-diol
(3e,5e,7e,9r,10r,11e,13e,18r,20s)-10-{[(2r,3s,4s,5r,6s)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-20-[(r)-[(2r,3r,4s,5r,6r)-2,4-dihydroxy-6-[(2r)-2-{[(2r,4s,5s,6s)-4-hydroxy-5-{[(2s,4r,5r,6r)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,6-dimethyloxan-2-yl]oxy}-3-methoxypropyl]-3,5-dimethyloxan-2-yl](hydroxy)methyl]-18-methoxy-3,5,7,9,13-pentamethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
(1'r,2s,3r,4s,6r,10's,13's)-3,4,7'-trihydroxy-6-methyl-2',9'-dioxo-12',15'-dioxaspiro[oxane-2,11'-tetracyclo[8.4.1.0¹,¹⁰.0³,⁸]pentadecane]-3',5',7'-trien-13'-ylacetic acid
(2s)-2-({[(3r,4e)-1-[(2s)-6-carbamimidamido-2-[(1-hydroxy-3-methylbut-2-en-1-ylidene)amino]hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-3-(1h-indol-3-yl)propanoic acid
C31H43N7O5 (593.3325507999999)
2-methoxy-3,5-dimethyl-6-(5-methylheptyl)pyran-4-one
(1r,2s,12r,21ar)-13-{[(2s,3r,4r,5r)-3-amino-4,5-dihydroxyoxan-2-yl]oxy}-1,12-dihydroxy-2,12-dimethyl-1h,2h,3h,13h,21ah-pyrrolo[1,2-a]azacyclononadecan-5-one
C28H38N2O7 (514.2678877999999)
5-(1,3-dihydroxy-2-methylpentyl)-3,5-dimethyloxolan-2-one
2-(1-hydroxy-5-methylhexyl)-6-methoxy-3,5-dimethylpyran-4-one
n-(23,25-dichloro-4-{[5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyloxan-2-yl]oxy}-14,22-dihydroxy-17-oxo-2,16-dioxapentacyclo[18.2.2.1⁹,¹³.0³,¹⁰.0⁴,⁸]pentacosa-1(22),5,7,9(25),10,12,20,23-octaen-19-yl)ethanimidic acid
C34H38Cl2N2O10 (704.1903388000001)
(3r,5r)-5-(1,3-dihydroxy-2-methylpentyl)-3,5-dimethyloxolan-2-one
2-[(2-{[17-ethylidene-12,15,22,29,36,39-hexahydroxy-14-(1-hydroxyethyl)-20,31-dimethyl-38,41-dimethylidene-19,43-dioxa-9,26,33-trithia-3,13,16,23,30,37,40,45,46,47,48,49-dodecaazaheptacyclo[40.2.1.1⁸,¹¹.1¹⁸,²¹.1²⁵,²⁸.1³²,³⁵.0²,⁷]nonatetraconta-1(44),2,4,6,8(49),10,12,15,18(48),20,22,25(47),27,29,32(46),34,36,39,42(45)-nonadecaen-4-yl]formamido}-1-hydroxyprop-2-en-1-ylidene)amino]-n-(2-oxopropyl)prop-2-enimidic acid
C50H47N15O13S3 (1161.2639772000002)
2-hydroxy-n-{2-hydroxy-5-[5-(hydroxymethyl)-1,3-benzoxazol-2-yl]phenyl}ethanimidic acid
{[(3r,4s,5r,6r)-5-hydroxy-6-({2-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-4-oxochromen-7-yl}oxy)-3-methoxy-2,2-dimethyloxan-4-yl]oxy}methanimidic acid
(2r,3r,4s,5r,6r)-2-{[(2r,3s,4s,5s,6r)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(1r,2r,4s)-2-[(2s,8r,9s,11r,13s,15s,16s)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]-4-hydroxycyclopentane-1-carboxylic acid
C28H43NO7 (505.30393680000003)
4-(1,3-dihydroxypentyl)-2,4,17,19-tetramethyl-5,26-dioxa-11-azatricyclo[21.2.1.0⁷,¹¹]hexacosa-13,19-diene-6,12,18-trione
(2s)-2-amino-n-[(2s)-1-{[(2s)-2-{[(2s)-2-amino-1-hydroxypropylidene]amino}-3-(1h-indol-3-yl)propanoyl]oxy}-3-(1h-indol-3-yl)-1-oxopropan-2-yl]propanimidic acid
n-{2-hydroxy-5-[5-(hydroxymethyl)-1,3-benzoxazol-2-yl]phenyl}carboximidic acid
5,6-dimethoxy-4,7-bis(4-methoxyphenyl)-1,3-benzothiazole
C23H21NO4S (407.1191226000001)
2-amino-4-[5-(hydroxymethyl)-1,3-benzoxazol-2-yl]phenol
3-[(4-hydroxyphenyl)methyl]-12,15,18-triisopropyl-9-(2-methylpropyl)-6-(sec-butyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
C36H58N6O7 (686.4366758000001)
(7s,14z,20z)-4-(1-hydroxy-3-oxopentyl)-2,4,18,20-tetramethyl-5,27-dioxa-12-azatricyclo[22.2.1.0⁷,¹²]heptacosa-14,20-diene-6,13,19-trione
(3s,6r,9r,12s,15r,18s)-3-[(2s)-butan-2-yl]-18-[(4-hydroxyphenyl)methyl]-9,12,15-triisopropyl-6-(2-methylpropyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
C36H58N6O7 (686.4366758000001)
(10s,13s)-13-(hydroxymethyl)-10-isopropyl-9-methyl-5-(2-methylbut-3-en-2-yl)-3,9,12-triazatricyclo[6.6.1.0⁴,¹⁵]pentadeca-1,4,6,8(15),11-pentaen-11-ol
4-hydroxy-3-methyl-6-(3-methylbutyl)-5-(2-methylpropyl)pyran-2-one
2-[(1s)-1-hydroxyheptyl]-6-methoxy-3,5-dimethylpyran-4-one
n-(2-{[5,13-diethyl-14-hydroxy-9-methyl-1-azacyclotetradec-1(14)-en-6-yl]oxy}-3,5-dihydroxy-6-methyloxan-4-yl)ethanimidic acid
C26H48N2O6 (484.35121879999997)
(3e,5e,7e,9s,10s,11e,13e,17r,18r,20r)-10-{[(2s,3r,4r,5s,6r)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-20-[(s)-[(2s,3s,4r,5s,6s)-2,4-dihydroxy-6-[(2s)-2-{[(2s,4r,5r,6r)-4-hydroxy-5-{[(2r,4s,5s,6s)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,6-dimethyloxan-2-yl]oxy}-3-methoxypropyl]-3,5-dimethyloxan-2-yl](hydroxy)methyl]-17-hydroxy-18-methoxy-3,5,7,9,13-pentamethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
3-acetyl-2,7-dihydroxy-1-methoxy-4,6,11-trioxo-4a,12-dihydro-1h-5-oxatetracene-12a-carboxylic acid
4',5,6-trimethoxy-4-(4-methoxyphenyl)-[1,1'-biphenyl]-2-ol
5-methoxy-6-[(4-methoxyphenyl)methylidene]-1-methyl-3-(phenylmethylidene)pyrazin-2-one
(3z,6z)-3-[(4-hydroxyphenyl)methylidene]-5-methoxy-6-[(4-methoxyphenyl)methylidene]pyrazin-2-ol
5,14-dihydroxy-3-(2-methylpropyl)-12-(sec-butyl)-1,4,10,13-tetraazatricyclo[13.3.0.0⁶,¹⁰]octadeca-4,13-diene-2,11-dione
5-(hydroxymethyl)-3-methyl-6-[(2r)-pentan-2-yl]pyran-2-one
2-methoxy-3,5-dimethyl-6-(5-methylhexanoyl)pyran-4-one
(3z,9s,10r,11z,13e,15e,17z,19z,21s)-7,21-dimethyl-1-azacyclodocosa-1,3,5,7,11,13,15,17,19-nonaene-2,9,10-triol
(7s)-4-(1,3-dihydroxypentyl)-2,4,17,19-tetramethyl-5,26-dioxa-11-azatricyclo[21.2.1.0⁷,¹¹]hexacosa-13,19-diene-6,12,18-trione
9,10-dihydroxy-7,21-dimethyl-1-azacyclodocosa-3,5,7,11,13,15,17,19-octaen-2-one
3,4,4'-trihydroxy-6-methyl-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-1'(10'),3',5',7'-tetraene-2',9',13'-trione
5-methoxy-4,7-bis(4-methoxyphenyl)-1,3-benzothiazol-6-ol
C22H19NO4S (393.1034734000001)
n-{2-hydroxy-5-[5-(hydroxymethyl)-1,3-benzoxazol-2-yl]phenyl}ethanimidic acid
(3s,6s,12s,15s)-3-[(2s)-butan-2-yl]-5,14-dihydroxy-12-(2-methylpropyl)-1,4,10,13-tetraazatricyclo[13.3.0.0⁶,¹⁰]octadeca-4,13-diene-2,11-dione
(7s,14z,20z)-4-(1,3-dihydroxypentyl)-2,4,18,20-tetramethyl-5,27-dioxa-12-azatricyclo[22.2.1.0⁷,¹²]heptacosa-14,20-diene-6,13,19-trione
(15s,16r,18r)-3,16-dihydroxy-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),3,7(27),8(13),9,11,20(25),21,23-decaene-16-carboxylic acid
C26H19N3O5 (453.13246440000006)
(3s,6s)-3-(1h-indol-3-ylmethyl)-6-methyl-3,6-dihydropyrazine-2,5-diol
(6z)-3-benzyl-6-[(4-methoxyphenyl)methylidene]-3h-pyrazine-2,5-diol
(2s)-2-({[(3r,4e)-1-[(2s)-6-carbamimidamido-2-{[hydroxy(phenyl)methylidene]amino}hexanoyl]-4-ethylidene-3-methylpyrrolidin-2-yl](hydroxy)methylidene}amino)-4-methylpentanoic acid
3,4'-dihydroxy-6-methyl-10'-(2-oxopropyl)-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-3',5',7'-triene-2',4,9',13'-tetrone
2-(5-hydroxy-5-methylhexyl)-6-methoxy-3,5-dimethylpyran-4-one
3,9-bis(1h-indol-3-ylmethyl)-15-isopropyl-12-methyl-18-(2-methylpropyl)-6-(sec-butyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
(1'r,3's,7's,8r,12's)-9-hydroxy-4,4,4',4',12',14'-hexamethyl-9',14'-diazaspiro[[1,4]dioxepino[2,3-g]indole-8,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecane]-10',13'-dione
C28H33N3O5 (491.24200880000006)
(3s,5s,13r,15r,17r,26r,28s,29r)-6,17,26-trimethyl-16-oxa-1,4,6,19-tetraazanonacyclo[17.9.1.1³,¹³.1⁴,²⁸.0⁵,¹³.0⁷,¹².0¹⁵,¹⁷.0²⁰,²⁵.0²⁶,²⁹]hentriaconta-7,9,11,20,22,24-hexaene-2,30-dione
C29H30N4O3 (482.23177899999996)
4-(1-hydroxy-3-oxopentyl)-2,4,18,20-tetramethyl-5,27-dioxa-12-azatricyclo[22.2.1.0⁷,¹²]heptacosa-14,20-diene-6,13,19-trione
3-[(4-hydroxyphenyl)methylidene]-5-methoxy-6-[(4-methoxyphenyl)methylidene]-1h-pyrazin-2-one
3,24-dimethoxy-2-methyl-4-(methylimino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1²,⁶.0⁷,²⁸.0⁸,¹³.0¹⁵,¹⁹.0²⁰,²⁷.0²¹,²⁶]nonacosa-8(13),9,11,14(28),15(19),16,20(27),21(26),22,24-decaen-16-ol
C29H26N4O4 (494.19539560000004)
6-benzyl-5-hydroxy-3-[(4-methoxyphenyl)methylidene]-1,6-dihydropyrazin-2-one
(1r,2r)-2-[(2s,4e,6z,8r,9s,11s,12s,13r,15s,16s)-7-cyano-8,12,16-trihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid
C28H43NO7 (505.30393680000003)
(1'r,3's,7's,8r,12'r)-9,12'-dihydroxy-4,4,4',4',12',14'-hexamethyl-9',14'-diazaspiro[[1,4]dioxepino[2,3-g]indole-8,5'-tetracyclo[5.5.2.0¹,⁹.0³,⁷]tetradecane]-10',13'-dione
C28H33N3O6 (507.23692380000006)
(1's,2r,3s,4s,6s,10's,11'r,15'r)-3,4,4'-trihydroxy-6-methyl-10'-(2-oxopropyl)-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-3',5',7'-triene-2',9',13'-trione
C23H24O10 (460.13694039999996)
3,13,23-triazahexacyclo[14.7.0.0²,¹⁰.0⁴,⁹.0¹¹,¹⁵.0¹⁷,²²]tricosa-1(16),2(10),4(9),5,7,11(15),12,17(22),18,20-decaen-12-ol
(2r,3r,6r,11'r,15'r)-3,4'-dihydroxy-6-methyl-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-1'(10'),3',5',7'-tetraene-2',4,9',13'-tetrone
n-[(3r,4r,14r,19s)-23,25-dichloro-4-{[(2s,3r,4r,5s)-5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyloxan-2-yl]oxy}-14,22-dihydroxy-17-oxo-2,16-dioxapentacyclo[18.2.2.1⁹,¹³.0³,¹⁰.0⁴,⁸]pentacosa-1(22),5,7,9(25),10,12,20,23-octaen-19-yl]ethanimidic acid
C34H38Cl2N2O10 (704.1903388000001)
(1r,3s,3'r,4's,6'r)-3',4',9-trihydroxy-6'-methyl-5,10-dioxo-3,4-dihydrospiro[naphtho[2,3-c]pyran-1,2'-oxan]-3-ylacetic acid
methyl 2-[(1s,3s,3'r,4s,6's)-3',4,9-trihydroxy-6'-methyl-4',5,10-trioxo-3,4-dihydrospiro[naphtho[2,3-c]pyran-1,2'-oxan]-3-yl]acetate
6-(2-hydroxypropan-2-yl)-3,9-dimethylcyclodeca-2,7-dien-1-one
(3s,6s)-3-benzyl-6-methyl-3,6-dihydropyrazine-2,5-diol
19-amino-23,25-dichloro-4-{[5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyloxan-2-yl]oxy}-14,22-dihydroxy-2,16-dioxapentacyclo[18.2.2.1⁹,¹³.0³,¹⁰.0⁴,⁸]pentacosa-1(22),5,7,9,11,13(25),20,23-octaen-17-one
C32H36Cl2N2O9 (662.1797746000001)
2,7-dihydroxy-1-methoxy-4,6,11-trioxo-3-propanoyl-4a,12-dihydro-1h-5-oxatetracene-12a-carboxylic acid
(1's,2r,3s,6s,10's,11'r,15'r)-3,4'-dihydroxy-6-methyl-10'-(2-oxopropyl)-12',16'-dioxaspiro[oxane-2,17'-tetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadecane]-3',5',7'-triene-2',4,9',13'-tetrone
3,4,7'-trihydroxy-6-methyl-2',9'-dioxo-12',15'-dioxaspiro[oxane-2,11'-tetracyclo[8.4.1.0¹,¹⁰.0³,⁸]pentadecane]-3',5',7'-trien-13'-ylacetic acid
3-benzyl-6-[(4-methoxyphenyl)methylidene]-1-methylpiperazine-2,5-dione
(3e,5e,7e,9r,10r,11e,13e,18r,20s)-10-{[(2r,3s,4s,5r,6s)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-20-{[(2s,3r,4s,5r,6r)-2,4-dihydroxy-6-[(2r)-2-{[(2r,4s,5s,6s)-4-hydroxy-5-{[(2s,4r,5r,6r)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,6-dimethyloxan-2-yl]oxy}-3-methoxypropyl]-3,5-dimethyloxan-2-yl]methyl}-18-methoxy-3,5,7,9,13-pentamethyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one
(6z)-5-methoxy-3,6-bis[(4-methoxyphenyl)methylidene]-1-methylpyrazin-2-one
2-{[(1-{6-carbamimidamido-2-[(1-hydroxy-3-methylbutylidene)amino]hexanoyl}-4-ethylidene-3-methylpyrrolidin-2-yl)(hydroxy)methylidene]amino}-3-(1h-indol-3-yl)propanoic acid
C31H45N7O5 (595.3481999999999)
2-(7-cyano-8,12,16-trihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid
C28H43NO7 (505.30393680000003)
(4r,7s,10s,13s,16r)-16-{[(2s)-2-{[(2s)-2-{[(2s)-2-{[(2s)-2-({[(3s,6s,12s,15s,23s,28as)-12-benzyl-23-(3-carbamimidamidopropyl)-1,4,7,10,13,18,21-heptahydroxy-3-(c-hydroxycarbonimidoylmethyl)-6-(1h-indol-3-ylmethyl)-24-oxo-3h,6h,9h,12h,15h,16h,17h,20h,23h,26h,27h,28h,28ah-pyrrolo[1,2-g]1,4,7,10,13,16,19,22-octaazacyclohexacosan-15-yl](hydroxy)methylidene}amino)-1-hydroxy-3-(c-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene]amino}-1-hydroxy-3-(1h-indol-3-yl)propylidene]amino}-1,3-dihydroxypropylidene]amino}-10-(3-carbamimidamidopropyl)-6,9,12,15-tetrahydroxy-7,13-diisopropyl-1,2-dithia-5,8,11,14-tetraazacycloheptadeca-5,8,11,14-tetraene-4-carboxylic acid
C88H121N27O24S2 (2003.8518786000002)
2-{[(1-{6-carbamimidamido-2-[(1-hydroxy-3-methylbutylidene)amino]hexanoyl}-4-ethylidene-3-methylpyrrolidin-2-yl)(hydroxy)methylidene]amino}-4-methylpentanoic acid
(3s,6s,9r,12r,15s,18r)-3-[(4-hydroxyphenyl)methyl]-6,12,15,18-tetraisopropyl-9-(2-methylpropyl)-1,4,7,10,13,16-hexaazacyclooctadeca-1,4,7,10,13,16-hexaene-2,5,8,11,14,17-hexol
methyl (15s,16s,18r)-3,16-dihydroxy-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),3,7(27),8(13),9,11,20(25),21,23-decaene-16-carboxylate
C27H21N3O5 (467.14811360000004)
2-{4-hydroxy-3-[(1-hydroxyethylidene)amino]phenyl}-1,3-benzoxazole-5-carboxylic acid
4-[5-(hydroxymethyl)-1,3-benzoxazol-2-yl]-3-methoxyphenol
3-ethyl-6-[(4s)-4-hydroxypent-2-en-2-yl]pyran-2-one
3',4',9-trihydroxy-6'-methyl-5,10-dioxo-3,4-dihydrospiro[naphtho[2,3-c]pyran-1,2'-oxan]-3-ylacetic acid
4-(1-hydroxy-3-oxopentyl)-2,4,17,19-tetramethyl-5,26-dioxa-11-azatricyclo[21.2.1.0⁷,¹¹]hexacosa-13,19-diene-6,12,18-trione
(3s,6z)-3-benzyl-5-hydroxy-6-[(4-methoxyphenyl)methylidene]-1-methyl-3h-pyrazin-2-one
13-(hydroxymethyl)-9-methyl-5-(2-methylbut-3-en-2-yl)-10-(sec-butyl)-3,9,12-triazatricyclo[6.6.1.0⁴,¹⁵]pentadeca-1,4,6,8(15),11-pentaen-11-ol
C23H33N3O2 (383.25726380000003)
3,7,15,19,23,31-hexamethyl-1,17-diazacyclodotriaconta-1,3,5,7,9,11,13,17,19,21,23,25,27,29-tetradecaene-2,18-diol
(3e,5e,7e,9z,11z,13s,17e,19e,21e,23z,25z,27s)-3,13,17,27-tetramethyl-1,15-diazacyclooctacosa-1,3,5,7,9,11,15,17,19,21,23,25-dodecaene-2,16-diol
C30H38N2O2 (458.29331279999997)