NCBI Taxonomy: 1294634

Crocodylia (ncbi_taxid: 1294634)

found 37 associated metabolites at order taxonomy rank level.

Ancestor: Archosauria

Child Taxonomies: Longirostres, Alligatoridae

Squalene

InChI=1/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24

C30H50 (410.39123)


Squalene is an unsaturated aliphatic hydrocarbon (carotenoid) with six unconjugated double bonds found in human sebum (5\\\\%), fish liver oils, yeast lipids, and many vegetable oils (e.g. palm oil, cottonseed oil, rapeseed oil). Squalene is a volatile component of the scent material from Saguinus oedipus (cotton-top tamarin monkey) and Saguinus fuscicollis (saddle-back tamarin monkey) (Hawleys Condensed Chemical Reference). Squalene is a component of adult human sebum that is principally responsible for fixing fingerprints (ChemNetBase). It is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All higher organisms produce squalene, including humans. It is a hydrocarbon and a triterpene. Squalene is a biochemical precursor to the whole family of steroids. Oxidation of one of the terminal double bonds of squalene yields 2,3-squalene oxide which undergoes enzyme-catalyzed cyclization to afford lanosterol, which is then elaborated into cholesterol and other steroids. Squalene is a low-density compound often stored in the bodies of cartilaginous fishes such as sharks, which lack a swim bladder and must therefore reduce their body density with fats and oils. Squalene, which is stored mainly in the sharks liver, is lighter than water with a specific gravity of 0.855 (Wikipedia) Squalene is used as a bactericide. It is also an intermediate in the manufacture of pharmaceuticals, rubber chemicals, and colouring materials (Physical Constants of Chemical Substances). Trans-squalene is a clear, slightly yellow liquid with a faint odor. Density 0.858 g / cm3. Squalene is a triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. It has a role as a human metabolite, a plant metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. Squalene is originally obtained from shark liver oil. It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. It is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy. Squalene is a natural product found in Ficus septica, Garcinia multiflora, and other organisms with data available. squalene is a metabolite found in or produced by Saccharomyces cerevisiae. A natural 30-carbon triterpene. See also: Olive Oil (part of); Shark Liver Oil (part of). A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene also has anti-fungal activity and can be used for the research of Trichophyton mentagrophytes research[2]. Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene also has anti-fungal activity and can be used for the research of Trichophyton mentagrophytes research[2].

   

Neocembrene

1,5,9-Cyclotetradecatriene, 1,5,9-trimethyl-12-(1-methylethenyl)-

C20H32 (272.2503872)


   

Citronellyl acetate

(3R)-3,7-dimethyloct-6-en-1-yl acetate

C12H22O2 (198.1619712)


Citronellyl acetate is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") It is used as a food additive Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects[1]. Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects[1].

   

Citronellyl butyrate

Butyric acid, 3,7-dimethyl-6-octenyl ester (8ci)

C14H26O2 (226.1932696)


Constituent of Ceylon citronella oil, tomato, orange juice and passion fruit juice. Flavouring ingredient. Citronellyl butyrate is found in many foods, some of which are garden tomato, citrus, fruits, and herbs and spices. Citronellyl butyrate is found in citrus. Citronellyl butyrate is a constituent of Ceylon citronella oil, tomato, orange juice and passion fruit juice. Citronellyl butyrate is a flavouring ingredient.

   

Squalen

2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene

C30H50 (410.39123)


   

(E)-beta-farnesene

7,11-dimethyl-3-methylidenedodeca-1,6,10-triene

C15H24 (204.18779039999998)


(e)-beta-farnesene, also known as 7,11-dimethyl-3-methylenedodeca-1,6,10-triene, is a member of the class of compounds known as sesquiterpenoids. Sesquiterpenoids are terpenes with three consecutive isoprene units (e)-beta-farnesene can be found in a number of food items such as safflower, lemon thyme, cauliflower, and root vegetables, which makes (e)-beta-farnesene a potential biomarker for the consumption of these food products. (e)-β-farnesene, also known as 7,11-dimethyl-3-methylenedodeca-1,6,10-triene, is a member of the class of compounds known as sesquiterpenoids. Sesquiterpenoids are terpenes with three consecutive isoprene units (e)-β-farnesene can be found in a number of food items such as safflower, lemon thyme, cauliflower, and root vegetables, which makes (e)-β-farnesene a potential biomarker for the consumption of these food products. (E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis[1][2]. (E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis[1][2].

   

Squalene

InChI=1\C30H50\c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4\h15-18,23-24H,9-14,19-22H2,1-8H3\b27-17+,28-18+,29-23+,30-24

C30H50 (410.39123)


Squalene, also known as (e,e,e,e)-squalene or all-trans-squalene, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Squalene can be found in a number of food items such as apricot, savoy cabbage, peach (variety), and bitter gourd, which makes squalene a potential biomarker for the consumption of these food products. Squalene can be found primarily in blood, feces, and sweat, as well as throughout most human tissues. In humans, squalene is involved in several metabolic pathways, some of which include risedronate action pathway, steroid biosynthesis, alendronate action pathway, and fluvastatin action pathway. Squalene is also involved in several metabolic disorders, some of which include cholesteryl ester storage disease, CHILD syndrome, hyper-igd syndrome, and wolman disease. Squalene is a natural 30-carbon organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives. Yeast cells have been genetically engineered to produce commercially useful quantities of "synthetic" squalene . COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Window width to select the precursor ion was 3 Da.; CONE_VOLTAGE was 20 V.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 19HP8024 to the Mass Spectrometry Society of Japan. Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene also has anti-fungal activity and can be used for the research of Trichophyton mentagrophytes research[2]. Squalene is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene also has anti-fungal activity and can be used for the research of Trichophyton mentagrophytes research[2].

   

3,7,11-trimethyldodeca-2,4-diene

3,7,11-trimethyldodeca-2,4-diene

C15H28 (208.2190888)


   

Citronellyl acetate

(3R)-3,7-dimethyloct-6-en-1-yl acetate

C12H22O2 (198.1619712)


Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects[1]. Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects[1].

   

WE 16:1

3,7-dimethyloct-6-en-1-yl hexanoate

C16H30O2 (254.224568)


   

CITRONELLYL BUTYRATE

CITRONELLYL BUTYRATE

C14H26O2 (226.1932696)


   

(4e)-3,7,11-trimethyldodeca-2,4-diene

(4e)-3,7,11-trimethyldodeca-2,4-diene

C15H28 (208.2190888)


   

(2e,4e,7s)-3,7,11-trimethyldodeca-2,4,10-triene

(2e,4e,7s)-3,7,11-trimethyldodeca-2,4,10-triene

C15H26 (206.2034396)


   

3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

C20H32O (288.24530219999997)


   

(2z,4e,7r)-3,7,11-trimethyldodeca-2,4-diene

(2z,4e,7r)-3,7,11-trimethyldodeca-2,4-diene

C15H28 (208.2190888)


   

(2z,4e,7r,10e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

(2z,4e,7r,10e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

C20H34 (274.2660364)


   

(2s,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11s,11ar)-4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

(2s,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11s,11ar)-4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

C27H46O5 (450.3345066)


   

(2r,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11ar)-4,7-dihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

(2r,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11ar)-4,7-dihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

C27H46O4 (434.3395916)


   

2-methyl-6-{4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl}heptanoic acid

2-methyl-6-{4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl}heptanoic acid

C27H46O5 (450.3345066)


   

3,7-dimethylocta-2,4-diene

3,7-dimethylocta-2,4-diene

C10H18 (138.1408428)


   

(4e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

(4e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

C20H34 (274.2660364)


   

(2r,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11s,11ar)-4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

(2r,6r)-6-[(1r,3as,3br,4r,5as,7r,9as,9bs,11s,11ar)-4,7,11-trihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl]-2-methylheptanoic acid

C27H46O5 (450.3345066)


   

(3e,7e,10r,13s)-3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

(3e,7e,10r,13s)-3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

C20H32O (288.24530219999997)


   

(6e,10e)-7,11,15-trimethyl-3-methylidenehexadeca-1,6,10,14-tetraene

(6e,10e)-7,11,15-trimethyl-3-methylidenehexadeca-1,6,10,14-tetraene

C20H32 (272.2503872)


   

(2z,4e,7r)-3,7,11-trimethyldodeca-2,4,10-triene

(2z,4e,7r)-3,7,11-trimethyldodeca-2,4,10-triene

C15H26 (206.2034396)


   

(4e)-3,7,11-trimethyldodeca-2,4,10-triene

(4e)-3,7,11-trimethyldodeca-2,4,10-triene

C15H26 (206.2034396)


   

7,11,15-trimethyl-3-methylidenehexadeca-1,6,10,14-tetraene

7,11,15-trimethyl-3-methylidenehexadeca-1,6,10,14-tetraene

C20H32 (272.2503872)


   

(1e,5e,9e,12s)-1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradeca-1,5,9-triene

(1e,5e,9e,12s)-1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradeca-1,5,9-triene

C20H32 (272.2503872)


   

(2e,4e)-3,7-dimethylocta-2,4-diene

(2e,4e)-3,7-dimethylocta-2,4-diene

C10H18 (138.1408428)


   

3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

C20H34 (274.2660364)


   

(6e)-2,6-dimethyl-10-methylidenedodeca-2,6-diene

(6e)-2,6-dimethyl-10-methylidenedodeca-2,6-diene

C15H26 (206.2034396)


   

(3e,7e,10r,13r)-3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

(3e,7e,10r,13r)-3,7,13-trimethyl-10-(prop-1-en-2-yl)cyclotetradeca-3,7-dien-1-one

C20H32O (288.24530219999997)


   

(2e,4e,7r,10e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

(2e,4e,7r,10e)-3,7,11,15-tetramethylhexadeca-2,4,10,14-tetraene

C20H34 (274.2660364)


   

3,7,11-trimethyldodeca-2,4,10-triene

3,7,11-trimethyldodeca-2,4,10-triene

C15H26 (206.2034396)


   

(2e,4e,7s)-3,7,11-trimethyldodeca-2,4-diene

(2e,4e,7s)-3,7,11-trimethyldodeca-2,4-diene

C15H28 (208.2190888)


   

1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradeca-1,5,9-triene

1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradeca-1,5,9-triene

C20H32 (272.2503872)


   

6-{4,7-dihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl}-2-methylheptanoic acid

6-{4,7-dihydroxy-9a,11a-dimethyl-tetradecahydro-1h-cyclopenta[a]phenanthren-1-yl}-2-methylheptanoic acid

C27H46O4 (434.3395916)