Chemical Formula: C7H16N4O2

Chemical Formula C7H16N4O2

Found 33 metabolite its formula value is C7H16N4O2

Homo-L-arginine

(2S)-2-amino-6-carbamimidamidohexanoic acid

C7H16N4O2 (188.1273196)


L-homoarginine, also known as N6-(aminoiminomethyl)-L-lysine or N6-amidino-L-lysine, is a member of the class of compounds known as L-alpha-amino acids. L-alpha-amino acids are alpha amino acids which have the L-configuration of the alpha-carbon atom. More specifically, L-homoarginine is a naturally occurring, non-proteinogenic, cationic amino acid. It is formed in the liver in a reaction catalyzed by L-arginine:glycine amidinotransferase (AGAT) when transferring the amidino group from arginine to lysine. It is an alternative substrate for nitric oxide (NO) synthase. L-homoarginine increases the availability of NO and thereby affects endothelial function. High homoarginine levels may exert positive actions that are relevant to cardiovascular health, including enhanced endothelial function, inhibition of platelet aggregation and stimulation of insulin secretion (PMID: 30866658). Recent studies have demonstrated that low serum homoarginine levels are a strong predictor of cardiovascular mortality (PMID: 24583919). L-homoarginine is a substrate of the human cationic amino acid CAT1 [solute carrier family 7 (SLC7A1)], CAT2A (SLC7A2A) or CAT2B (SLC7A2B) (PMID: 28684763). According to published human metabolomic data, L-homoarginine can be found primarily in blood, cerebrospinal fluid (CSF), and urine, as well as in human intestinal and testes tissues. Moreover, L-homoarginine has been found to be associated with liver cirrhosis and the genetic disorder, hyperargininemia. Homoarginine is an organ-specific uncompetitive inhibitor of human liver and bone alkaline phosphohydrolase (PMID: 5063678). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

   

L-Targinine

(2S)-2-amino-5-(3-methylcarbamimidamido)pentanoic acid

C7H16N4O2 (188.12731960000002)


L-Targinine is found in pulses. L-Targinine is isolated from broad bean seed L-Targinine has been identified in the human placenta (PMID: 32033212). C471 - Enzyme Inhibitor > C29574 - Nitric Oxide Synthase Inhibitor D004791 - Enzyme Inhibitors

   

Methylarginine

2-amino-5-(N-methylcarbamimidamido)pentanoic acid

C7H16N4O2 (188.12731960000002)


   

delta-N-Methylarginine

2-amino-5-(N-methylcarbamimidamido)pentanoic acid

C7H16N4O2 (188.12731960000002)


   

Methyl L-argininate

methyl 2-amino-5-[(diaminomethylidene)amino]pentanoate

C7H16N4O2 (188.12731960000002)


   

N2-Methyl-L-arginine

5-[(diaminomethylidene)amino]-2-(methylamino)pentanoic acid

C7H16N4O2 (188.12731960000002)


   

(2S)-2-Amino-5-(diaminomethylideneamino)-4-methylpentanoic acid

(2S)-2-Amino-5-(diaminomethylideneamino)-4-methylpentanoic acid

C7H16N4O2 (188.12731960000002)


   
   

Homoarginine

Homo-L-arginine

C7H16N4O2 (188.12731960000002)


An L-lysine derivative that is the L-enantiomer of homoarginine. Homoarginine is a guanidino compounds of guanidinoethanesulfonic acid. It is an organ-specific uncompetitive inhibitor of human liver and bone alkaline phosphohydrolase. (PMID 5063678). L-Homoarginine is found in grass pea. H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

   
   
   
   
   
   
   
   

Heptanedioic acid,1,7-dihydrazide

Heptanedioic acid,1,7-dihydrazide

C7H16N4O2 (188.12731960000002)


   
   
   

delta-N-Methylarginine

2-amino-5-(N-methylcarbamimidamido)pentanoic acid

C7H16N4O2 (188.12731960000002)


   

3-Methylarginine

3-Methylarginine

C7H16N4O2 (188.12731960000002)


A non-proteinogenic alpha-amino acid that is arginine carrying a methyl group at position 3. It is a rare amino acid produced by Pseudomonas syringae syringae, with a strong toxicity against Pseudomonas syringae glycinea, two soybean pathogens.

   

(2S)-2-Amino-5-(diaminomethylideneamino)-4-methylpentanoic acid

(2S)-2-Amino-5-(diaminomethylideneamino)-4-methylpentanoic acid

C7H16N4O2 (188.12731960000002)


   

(2S)-2-ammonio-5-(N-methylcarbamimidamido)pentanoate

(2S)-2-ammonio-5-(N-methylcarbamimidamido)pentanoate

C7H16N4O2 (188.12731960000002)


   
   

5-methyl-L-arginine

5-methyl-L-arginine

C7H16N4O2 (188.12731960000002)


A non-proteinogenic L-alpha-amino acid that is L-arginine substituted by a methyl group at position 5.

   
   
   

Tilarginine

Tilarginine

C7H16N4O2 (188.12731960000002)


C471 - Enzyme Inhibitor > C29574 - Nitric Oxide Synthase Inhibitor D004791 - Enzyme Inhibitors

   

N(5)-methyl-L-arginine

N(5)-methyl-L-arginine

C7H16N4O2 (188.12731960000002)


A non-proteinogenic L-alpha-amino acid that is L-arginine substituted by a methyl group at N(5)-position.

   

N(omega)-methyl-L-arginine zwitterion

N(omega)-methyl-L-arginine zwitterion

C7H16N4O2 (188.12731960000002)


The zwitterion obtained from N(omega)-methyl-L-arginine by transfer of a proton from the carboxylic acid group to the alpha-amino group.

   

N(Omega)-methyl-L-arginine

N(Omega)-methyl-L-arginine

C7H16N4O2 (188.12731960000002)


A L-arginine derivative with a N(omega)-methyl substituent.

   

(3R)-3-Methyl-L-arginine

(2S,3R)-2-amino-5-(diaminomethylideneamino)-3-methylpentanoic acid

C7H16N4O2 (188.12731960000002)