Chemical Formula: C6H8O5
Chemical Formula C6H8O5
Found 40 metabolite its formula value is C6H8O5
2-Oxoadipic acid
2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein (PMID: 10655159, 16183823, 11083877). Oxoadipic acid is found to be associated with alpha-aminoadipic aciduria, which is an inborn error of metabolism. Present in pea seedlings KEIO_ID K009 Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
3-Oxoadipic acid
3-Oxoadipic acid is a regularly occurring Adipic dicarboxylic acid human metabolite found occasionally in biofluids of healthy individuals. (PMIDs 8340451, 1769109, 2338430) Increased amounts of 3-Oxoadipic acid are excreted after ingestion of Sebacic acid, supporting the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation. (PMID 3220884) [HMDB] 3-Oxoadipic acid is a regularly occurring Adipic dicarboxylic acid human metabolite found occasionally in biofluids of healthy individuals. (PMIDs 8340451, 1769109, 2338430) Increased amounts of 3-Oxoadipic acid are excreted after ingestion of Sebacic acid, supporting the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation. (PMID 3220884).
2-Methyl-4-oxopentanedioic acid
2-Methyl-4-oxopentanedioic acid is found in fruits. 2-Methyl-4-oxopentanedioic acid is a constituent of Tamarindus indica (tamarind). Constituent of Tamarindus indica (tamarind). 2-Methyl-4-oxopentanedioic acid is found in fruits.
(2R,3S)-2,3-dimethylmalate
(2r,3s)-2,3-dimethylmalate is soluble (in water) and a weakly acidic compound (based on its pKa). (2r,3s)-2,3-dimethylmalate can be found in a number of food items such as pepper (c. frutescens), oregon yampah, green bean, and red raspberry, which makes (2r,3s)-2,3-dimethylmalate a potential biomarker for the consumption of these food products.
5,6-Dihydro-3,5-dihydroxy-6-hydroxymethyl-2H-pyran-2-one
Oxoadipic acid
An oxo dicarboxylic acid that is adipic acid substituted by an oxo group at position 2. Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
3-ketoadipate
An oxo dicarboxylic acid consisting of adipic acid having a single oxo group at the 3-position.
Oxoadipate
Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
(2R,3R)-3,5-dihydroxy-2-(hydroxymethyl)-2,3-dihydropyran-4-one
(4R,5S,6R)-2,4,5,6-tetrahydroxycyclohex-2-en-1-one
2,4-didehydro-3-deoxy-L-rhamnonic acid
A ketoaldonic acid that is rhamnonic acid which is lacking the 3-hydroxy group, while those at positions 2 and 4 have been oxidised to the corresponding ketones.
3-hydroxy-3-methylglutarate(2-)
A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid.