Chemical Formula: C22H30O3
Chemical Formula C22H30O3
Found 99 metabolite its formula value is C22H30O3
Megestrol
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03A - Hormonal contraceptives for systemic use > G03AC - Progestogens G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03D - Progestogens > G03DB - Pregnadien derivatives L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02A - Hormones and related agents > L02AB - Progestogens C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents D000970 - Antineoplastic Agents
2alpha-Methyl-11-oxoprogesterone
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid is found in nuts. 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid is a minor constituent of cashew nut shel D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
Guggulsterone
Guggulsterone is an ingredient in many nutritional supplements. Guggulsterone is a plant sterol derived from the gum resin (guggulu) of the tree Commiphora mukul. This sterol can inhibit NF-κB activation and downregulate the expression of inflammatory gene products such as COX-2 and MMP-9, which are major players in the development of arthritis. Guggulsterone also can suppress osteoclastogenesis induced by RANKL (receptor activator of NF-κB ligand), a bone-resorbing cytokine. The anti-inflammatory activity of C. mukul (guggul) has been compared with that of NSAIDs, namely phenylbutazone and ibuprofen. Guggulsterone is used to treat obesity, diabetes, hyperlipidemia, atherosclerosis, and osteoarthritis, and has been recently shown to antagonize the farnesoid X receptor and decrease the expression of bile acid-activated genes. It modulates activation of NF-kappaB, which has been closely linked with inflammatory diseases affected by guggulsterone. (PMID: 17475558, 15322087) [HMDB] Guggulsterone is an ingredient in many nutritional supplements. Guggulsterone is a plant sterol derived from the gum resin (guggulu) of the tree Commiphora mukul. This sterol can inhibit NF-κB activation and downregulate the expression of inflammatory gene products such as COX-2 and MMP-9, which are major players in the development of arthritis. Guggulsterone also can suppress osteoclastogenesis induced by RANKL (receptor activator of NF-κB ligand), a bone-resorbing cytokine. The anti-inflammatory activity of C. mukul (guggul) has been compared with that of NSAIDs, namely phenylbutazone and ibuprofen. Guggulsterone is used to treat obesity, diabetes, hyperlipidemia, atherosclerosis, and osteoarthritis, and has been recently shown to antagonize the farnesoid X receptor and decrease the expression of bile acid-activated genes. It modulates activation of NF-kappaB, which has been closely linked with inflammatory diseases affected by guggulsterone. (PMID: 17475558, 15322087).
17-Hydroxymethylethisterone
17-Hydroxymethylethisterone is a metabolite of danazol. Danazol is a derivative of the synthetic steroid ethisterone, a modified testosterone. Also known as 17alpha-ethinyl testosterone. Before becoming available as a generic drug, Danazol was marketed as Danocrine in the United States. It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis in the early 1970s. Although effective for endometriosis, its use is limited by its masculinizing side-effects. (Wikipedia)
14-oxo-DoHE(1-)
14-oxo-DoHE(1-) is also known as 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-Docosahexaenoate. 14-oxo-DoHE(1-) is considered to be practically insoluble (in water) and acidic
Pregn-4-en-20-yn-3-one, 17-hydroxy-2-(hydroxymethyl)-, (2alpha,17alpha)-
2-Hydroxy-6-pentadeca-8,11,14-trienyl benzoic acid
Trimegestone
(E, E)-form/2, 5-Dihydroxy-3-(3, 7, 11-trimethyl-2, 6, 10-dodecatrienyl)benzaldehyde|3-farnesyl-2,5-dihydroxybenzaldehyde
20,21,22,23,24,25,26,27-octanorcucurbit-5-ene-3,7,16-trione|octanorcucurbitacin B
20,21,22,23,24,25,26,27-octanorcucurbit-5-ene-3,7,17-trione|octanorcucurbitacin A
10-acetoxy-9-hydroxyamphilecta-8,10,12,14-tetraene
2-(7-hydroxy-4,8-dimethyl-3E,8-nonadienyl)-5-hydroxy-2,7-dimethyl-2H-chromene|daurichromene A
5-methyl-2-[(2E,7Z)-3,7,11-trimethyl-2,7-dodecadien-9-onyl]benzo-1,4-quinone
2-[1,3,5,7-Tetramethyl-8-ethylbicyclo[4.2.0]octa-2,4-diene-7-yl]-3,5-dimethyl-6-methoxy-4H-pyran-4-one
5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6-dodecadien-9-onyl]benzo-1,4-quinone
Tricyclo[6.3.1.0(1,5)]dodecan-9-ol, 2-benzoyloxy-4,4,8-trimethyl-
2-(3-hydroxy-8-methyl-4-methyliden-7-nonaenyl)-5-hydroxy-2,7-dimethyl-2H-chromene|daurichromene B
7-oxo-20,21,22,23,24,25,26,27-octanor-14,18-cycloapotirucalla-1-en-3,4-olide|simaroubin E
2R-(9-hydroxy-4,8-dimethyl-3E,7E-nonadienyl)-5-hydroxy-2,7-dimethyl-2H-chromene|daurichromene D
2(R),3(S),4(S)-3,18-methylene-2alpha-acetoxyspongia-13(16),14-diene
12-Acetoxy-abieta-8,11,13-trien-7-on|12-acetoxy-abieta-8,11,13-trien-7-one|sugiol acetate|Sugiol-Acetat|Sugiolacetat
3-geranyl-4-hydroxy-5-(3,3-dimethylallyl)-benzoicacid|3-geranyl-4-hydroxy-5-(3,3-dimethylallyl)-benzoic acid|3-geranyl-4-hydroxy-5-(3-methyl-2-butenyl)benzoic acid|3-geranyl-4-hydroxy-5-(3?,3?-dimethylallyl)benzoic acid|5-geranyl-4-hydroxy-5-(3-methyl-2-butenyl)-benzoic acid|myrsinoic acid|myrsinoic acid A
2-(8-hydroxy-4,8-dimethyl-3E,6Z-nonadienyl)-5-hydroxy-2,7-dimethyl-2H-chromene|daurichromene C
5beta,19-epoxy-20,21,22,23,24,25,26,27-octanorcucurbit-6-ene-3,17-dione|octanorcucurbitacin C
C22H30O3_2-Hydroxy-6-[(8Z,11Z)-8,11,14-pentadecatrien-1-yl]benzoic acid
2-hydroxy-6-[(8Z,11Z)-pentadeca-8,11,14-trienyl]benzoic acid
4Z,7Z,10Z,13Z,15E,19Z-17-keto-docosapentaenoic acid
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
(6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Trimegestone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C389 - Oral Contraceptive
Myrsinoic acid A
A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a geranyl group at position 3 and a prenyl group at position 5. Isolated from Myrsine seguinii, it exhibits anti-inflammatory activity.
(4Z,7Z,10Z,12E,14E)-15-{(2S,3S)-3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,12,14-pentaenoic acid
(13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid
An epoxy fatty acid consisting of (4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid having an epoxy group at the 13,14-position. An intermediate lipid in specialized proresolving mediators
(4Z,7Z,10Z,13Z,15E,19Z)-17-Oxodocosahexaenoic acid
An oxodocosahexaenoic acid that is (4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoic acid in which the oxo group is located at position 17. An intermediate of specialised proresolving mediators.
(4Z,7Z,10Z,14E,16Z,19Z)-13-Oxodocosahexaenoic acid
An oxodocosahexaenoic acid that is (4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoic acid in which the oxo group is located at position 13. An intermediate of specialised proresolving mediators.
omega-(3-Oxo-17-beta-hydroxy-4-androsten-17-alpha-yl) propionic acid lactone
14-oxo-DoHE
An oxo fatty acid that consists of (4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoic acid carrying a single oxo substituent at position 14.
(4Z,7Z,10Z,13Z)-15-{(3R)-3-[(2Z)-pent-2-en-1-yl]oxiran-2-ylidene}pentadeca-4,7,10,13-tetraenoic acid
6beta,17-Dihydroxy-3,5-cyclo-5alpha,17alpha-pregn-20-ene-21-carboxylic acid, gamma-lactone
(4Z,7Z,10Z,13Z)-15-{(3S)-3-[(2Z)-pent-2-en-1-yl]oxiran-2-ylidene}pentadeca-4,7,10,13-tetraenoic acid
(17R)-17-ethynyl-17-hydroxy-2-(hydroxymethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
(2R,8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-spiro[cyclopenta[a]phenanthrene-17,2-furan]-3,5(2H,4H)-dione
(10,13-Dimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) propanoate
(4Z,8E,10Z,13Z,16Z,19Z)-7-oxodocosahexaenoic acid
A oxodocosahexaenoic acid that consists of (4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoic acid carrying an oxo substituent at position 7. An intermediate of specialised proresolving mediators.
(16S,17S)-epoxy-(4Z,7Z,10Z,12E,14E,19Z)-docosahexaenoic acid
An epoxy fatty acid consisting of (4Z,7Z,10Z,12E,14E,19Z)-docosahexaenoic acid having an epoxy group located at the 16,17-position. An intermediate lipid in specialized proresolving mediators.