Chemical Formula: C20H23N7O6
Chemical Formula C20H23N7O6
Found 15 metabolite its formula value is C20H23N7O6
5,10-Methylene-THF
5,10-Methylene-THF is an intermediate in glycine, serine and threonine metabolism and one carbon metabolism. 5,10-CH2-THF can also be used as a coenzyme in the biosynthesis of thymidine. More specifically it is the C1-donor in the reactions catalyzed by thymidylate synthase and thymidylate synthase (FAD). It also acts as a coenzyme in the synthesis of serine from glycine via the enzyme serine hydroxymethyl transferase. 5,10-Methylene-THF is a substrate for Methylenetetrahydrofolate reductase. This enzyme converts 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This reaction is required for the multistep process that converts the amino acid homocysteine to methionine. The body uses methionine to make proteins and other important compounds. 5,10-CH2-THF is a substrate for many enzymes including Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase (mitochondrial), Aminomethyltransferase (mitochondrial), Serine hydroxymethyltransferase (mitochondrial), Methylenetetrahydrofolate reductase, C-1-tetrahydrofolate synthase (cytoplasmic), Serine hydroxymethyltransferase (cytosolic) and Thymidylate synthase. 5,10-Methylene-THF is an intermediate in the metabolism of Methane and the metabolism of Nitrogen. It is a substrate for Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase (mitochondrial), Aminomethyltransferase (mitochondrial), Serine hydroxymethyltransferase (mitochondrial), Methylenetetrahydrofolate reductase, C-1-tetrahydrofolate synthase (cytoplasmic), Serine hydroxymethyltransferase (cytosolic) and Thymidylate synthase. [HMDB] COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
5-Methyldihydrofolic acid
5-Methyldihydrofolic acid is a biopterin derivative present in human body fluids and tissues. (PMID: 932231) [HMDB] 5-Methyldihydrofolic acid is a biopterin derivative present in human body fluids and tissues. (PMID: 932231).
(6R)-5,10-Methylenetetrahydrofolate
2-[[4-[(2-Amino-1-methyl-4-oxo-2,3-dihydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
2-[[4-[(2-Amino-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]-4-methylidenepentanedioic acid
5-Methyldihydrofolic acid
A member of the class of dihydrofolic acids that is dihydrofolic acid carrying a methyl substituent at position 5.
(6R)-5,10-Methylenetetrahydrofolate
C2140 - Adjuvant > C2078 - Folic Acid Derivative
5,10-Methylenetetrahydrofolic acid
C2140 - Adjuvant > C2078 - Folic Acid Derivative
(6R)-5,10-Methylenetetrahydrofolic acid
The (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid.
5-Methyltetrahydrofolate(2-)
A dicarboxylic acid dianion resulting from the deprotonation of the two carboxy groups of 5-methyltetrahydrofolic acid; major species at pH 7.3.