Chemical Formula: C11H15N5O5
Chemical Formula C11H15N5O5
Found 66 metabolite its formula value is C11H15N5O5
2-Methylguanosine
C11H15N5O5 (297.10731400000003)
2-Methylguanosine is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, the DNA becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. (PMID: 17336316, 17154124, 3506820, 17044778, 17264127) [HMDB] 2-Methylguanosine is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, the DNA becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. (PMID: 17336316, 17154124, 3506820, 17044778, 17264127). N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's. N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's.
1-Methylguanosine
C11H15N5O5 (297.10731400000003)
1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours. These nucleosides have been proposed as tumour markers. Their measurement could provide a non-invasive diagnostic method, help identify different cancers, and monitor any therapeutic effects (PMID:9129323). 1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours and they have been proposed as tumour markers. Their 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1]. 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1].
3'-O-Methylguanosine
C11H15N5O5 (297.10731400000003)
3-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. (PMID: 3506820, 17044778, 17264127, 16799933) [HMDB] 3-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. (PMID: 3506820, 17044778, 17264127, 16799933). 3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis[1].
Nelarabine
C11H15N5O5 (297.10731400000003)
Nelarabine is only found in individuals that have used or taken this drug. It is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity.Once nelarabine is metabolized into ara-GTP, the metabolite accumulates in leukemic blasts and incorporates into DNA to exert its S phase-specific cytotoxic effects, leading to the induction of fragmentation and apoptosis. Ara-GTP competes with endogenous deoxyGTP (dGTP) for incorporation into DNA. Once ara-GTP is incorporated at the 3 end of DNA, further DNA elongation is inhibited, which signals apoptosis and leads to cellular destruction. Additional cytotoxic activities may exist, but these are not fully understood. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01B - Antimetabolites > L01BB - Purine analogues C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL)[1].
2'-C-Methylguanosine
C11H15N5O5 (297.10731400000003)
2-O-methylguanosine
C11H15N5O5 (297.10731400000003)
Guanosine with the hydrogen on the hydroxyl at position C-2 substituted with a methyl group. CONFIDENCE standard compound; INTERNAL_ID 318 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].
7-Methylguanosine
C11H15N5O5 (297.10731400000003)
Nelarabine
C11H15N5O5 (297.10731400000003)
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01B - Antimetabolites > L01BB - Purine analogues C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL)[1].
1-methylguanosine
C11H15N5O5 (297.10731400000003)
Guanosine substituted with a methyl group at position N-1. 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1]. 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1].
3-O-Methylguanosine
C11H15N5O5 (297.10731400000003)
Guanosine with the hydrogen on the hydroxyl at position C-3 substituted with a methyl group. 3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis[1].
N-Methylguanosine
C11H15N5O5 (297.10731400000003)
CONFIDENCE standard compound; INTERNAL_ID 319 N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's. N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's.
7-Methylguanosine; AIF; CE0; CorrDec
C11H15N5O5 (297.10731400000003)
7-Methylguanosine; AIF; CE10; CorrDec
C11H15N5O5 (297.10731400000003)
7-Methylguanosine; AIF; CE30; CorrDec
C11H15N5O5 (297.10731400000003)
7-Methylguanosine; AIF; CE0; MS2Dec
C11H15N5O5 (297.10731400000003)
7-Methylguanosine; AIF; CE10; MS2Dec
C11H15N5O5 (297.10731400000003)
7-Methylguanosine; AIF; CE30; MS2Dec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE0; CorrDec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE10; CorrDec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE30; CorrDec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE0; MS2Dec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE10; MS2Dec
C11H15N5O5 (297.10731400000003)
N2-Methylguanosine; AIF; CE30; MS2Dec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE0; CorrDec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE10; CorrDec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE30; CorrDec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE0; MS2Dec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE10; MS2Dec
C11H15N5O5 (297.10731400000003)
N1-Methylguanosine; AIF; CE30; MS2Dec
C11H15N5O5 (297.10731400000003)
3-OMG
C11H15N5O5 (297.10731400000003)
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis[1].
n-[6,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6-oxo-1h-purin-2-yl]acetamide
C11H15N5O5 (297.10731400000003)
2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1H-purin-6-one
C11H15N5O5 (297.10731400000003)
N(2)-Methylguanosine
C11H15N5O5 (297.10731400000003)
Guanosine with the hydrogen on the amine at position N-2 substituted with a methyl group.
6-O-Methyl Guanosine
C11H15N5O5 (297.10731400000003)
6-O-Methyl Guanosine is a modified nucleoside[1]. 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line[2].
7-Methylguanosine
C11H15N5O5 (297.10731400000003)
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8?±?7.5?μM. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8?±?7.5?μM.
alpha-D-Arabinofuranosyladenine
C11H15N5O5 (297.10731400000003)
{"Ingredient_id": "HBIN015484","Ingredient_name": "alpha-D-Arabinofuranosyladenine","Alias": "(2S,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-methylol-tetrahydrofuran-3,4-diol; Adenine, 9-alpha-D-arabinofuranosyl-; (2S,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 9-alpha-D-Arabinofuranosyladenine; NSC 70422; 6936-84-1; AIDS023910; NSC 40584; 9H-Purin-6-amine, 9-alpha-D-arabinofuranosyl- (9CI); (2S,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenine, 9-alpha-D-arabinofuranosyl- (8CI); (2S,3S,4S,5R)-2-(6-amino-9-purinyl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; AIDS-023910","Ingredient_formula": "C11H15N5O5","Ingredient_Smile": "C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N","Ingredient_weight": "297.27","OB_score": "20.89729146","CAS_id": "6936-84-1","SymMap_id": "SMIT12080","TCMID_id": "NA","TCMSP_id": "MOL011145","TCM_ID_id": "NA","PubChem_id": "96368","DrugBank_id": "NA"}
(2r,3r,4s,5r)-2-(6-amino-2-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
C11H15N5O5 (297.10731400000003)
2-[6-hydroxy-2-(methylimino)-3h-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
C11H15N5O5 (297.10731400000003)